HK83293A - Composition of pregnanolole comprising a stable oil-in-water emulsion - Google Patents

Composition of pregnanolole comprising a stable oil-in-water emulsion Download PDF

Info

Publication number
HK83293A
HK83293A HK832/93A HK83293A HK83293A HK 83293 A HK83293 A HK 83293A HK 832/93 A HK832/93 A HK 832/93A HK 83293 A HK83293 A HK 83293A HK 83293 A HK83293 A HK 83293A
Authority
HK
Hong Kong
Prior art keywords
amount
oil
pregnanolone
composition
emulsion
Prior art date
Application number
HK832/93A
Other languages
German (de)
English (en)
French (fr)
Inventor
Roland Ingolf Jeppsson
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of HK83293A publication Critical patent/HK83293A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK832/93A 1986-02-13 1993-08-12 Composition of pregnanolole comprising a stable oil-in-water emulsion HK83293A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8600632A SE8600632D0 (sv) 1986-02-13 1986-02-13 Novel pharmaceutical composition

Publications (1)

Publication Number Publication Date
HK83293A true HK83293A (en) 1993-08-20

Family

ID=20363448

Family Applications (1)

Application Number Title Priority Date Filing Date
HK832/93A HK83293A (en) 1986-02-13 1993-08-12 Composition of pregnanolole comprising a stable oil-in-water emulsion

Country Status (14)

Country Link
US (1) US5028600A (cg-RX-API-DMAC10.html)
EP (1) EP0233849B1 (cg-RX-API-DMAC10.html)
JP (1) JPH0788305B2 (cg-RX-API-DMAC10.html)
AT (1) ATE64526T1 (cg-RX-API-DMAC10.html)
CA (1) CA1301651C (cg-RX-API-DMAC10.html)
DE (1) DE3770830D1 (cg-RX-API-DMAC10.html)
DK (1) DK175504B1 (cg-RX-API-DMAC10.html)
ES (1) ES2037742T3 (cg-RX-API-DMAC10.html)
FI (1) FI88676C (cg-RX-API-DMAC10.html)
GR (1) GR3002299T3 (cg-RX-API-DMAC10.html)
HK (1) HK83293A (cg-RX-API-DMAC10.html)
NO (1) NO175040B (cg-RX-API-DMAC10.html)
SE (1) SE8600632D0 (cg-RX-API-DMAC10.html)
SG (1) SG102892G (cg-RX-API-DMAC10.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302295D0 (sv) * 1993-07-02 1993-07-02 Kabi Pharmacia Ab New pharmaceutical composition
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
AU8779898A (en) * 1997-08-11 1999-03-01 Weider Nutrition International, Inc. Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
EP1105096B1 (en) 1998-08-19 2003-10-29 Skyepharma Canada Inc. Injectable aqueous dispersions of propofol
WO2002053102A2 (en) * 2000-12-29 2002-07-11 The Trustees Of Columbia University In The City Of New York Use of iv emulsions with different triglyceride composition, particle size and apolipoprotein e for targeted tissue delivery of hydrophobic compounds
KR101020687B1 (ko) 2002-07-02 2011-03-11 니코메드 게엠베하 사이클레소나이드 함유 멸균 수성 현탁액
PE20050941A1 (es) * 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
EP1799266A2 (en) * 2004-09-13 2007-06-27 Bharat Serums & Vaccines Ltd. Stable emulsion compositions for intravenous administration having antimicrobial preservative efficacy
CN104739765A (zh) * 2011-01-14 2015-07-01 卡思伯特·O·辛普金斯 用于处理与缺乏血液供给、休克和神经损伤相关的疾病的方法和组合物
WO2013043985A1 (en) * 2011-09-23 2013-03-28 The Regents Of The University Of California Edible oils to enhance delivery of orally administered steroids
RU2019104004A (ru) 2012-01-23 2019-03-07 Сейдж Терапьютикс, Инк. Лекарственные формы нейроактивных стероидов и способы лечения нарушений цнс
US20140050789A1 (en) 2012-08-13 2014-02-20 The Regents Of The University Of California Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids
LT2887944T (lt) 2012-08-21 2022-01-10 Sage Therapeutics, Inc. Alopregnanolonas, skirtas atsparios epileptinės būklės gydymui
EP2925327B1 (en) 2012-11-30 2024-01-10 The Regents of The University of California Allopregnanolone for treating, reducing or mitigating symptoms of post-partum depression
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
CN109414444A (zh) 2016-03-08 2019-03-01 萨奇治疗股份有限公司 神经活性类固醇、其组合物及用途
CA3123002A1 (en) * 2018-12-10 2020-06-18 Halo Science LLC Stable formulations of anesthetics and associated dosage forms
CA3151334C (en) * 2019-08-19 2024-04-09 Arizona Board Of Regents On Behalf Of The University Of Arizona Topical neurosteroid formulations
US11969434B1 (en) 2022-08-29 2024-04-30 Lipocine Inc. Oral allopregnanolone compositions and methods of use
CN114344309B (zh) * 2021-12-30 2024-02-06 南京迈诺威医药科技有限公司 一种别孕烷醇酮衍生物自乳化制剂及其制备方法
US12186327B2 (en) 2022-08-29 2025-01-07 Lipocine Inc. Oral allopregnanolone compositions and methods of use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1215702B (de) * 1962-07-03 1966-05-05 Merck Ag E Verfahren zur Herstellung von 1alpha-Alkylthio-3-keto-androstanen
CA895860A (en) * 1969-11-05 1972-03-21 Kruger Gunther PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXY-5.beta.-PREGNAN-20-ONE
US3917830A (en) * 1970-12-17 1975-11-04 Glaxo Lab Ltd Steroidal anaesthetic composition for intraveneous injection
US3900561A (en) * 1970-12-17 1975-08-19 Glaxo Lab Ltd Pharmaceutical compositions
US4168308A (en) * 1976-03-12 1979-09-18 Apoteksvarucentralen Vitrum Ab Composition for enhancing the administration of pharmacologically active agents
JPS609726B2 (ja) * 1980-05-15 1985-03-12 株式会社 ミドリ十字 ステロイド製剤
JPS5716818A (en) * 1981-04-25 1982-01-28 Green Cross Corp:The Steroid fatty emulsion
JPS60258110A (ja) * 1984-06-05 1985-12-20 Daigo Eiyou Kagaku Kk 静脈注射可能なプロゲステロン乳化注射液

Also Published As

Publication number Publication date
NO175040B (no) 1994-05-16
SG102892G (en) 1992-12-04
DK62187D0 (da) 1987-02-06
DK62187A (da) 1987-08-14
FI88676C (fi) 1993-06-28
CA1301651C (en) 1992-05-26
EP0233849B1 (en) 1991-06-19
NO175040C (cg-RX-API-DMAC10.html) 1994-08-24
SE8600632D0 (sv) 1986-02-13
ES2037742T3 (es) 1993-07-01
EP0233849A1 (en) 1987-08-26
DK175504B1 (da) 2004-11-15
DE3770830D1 (de) 1991-07-25
FI870589L (fi) 1987-08-14
FI870589A0 (fi) 1987-02-12
US5028600A (en) 1991-07-02
NO870560L (no) 1987-08-14
ATE64526T1 (de) 1991-07-15
GR3002299T3 (en) 1992-12-30
NO870560D0 (no) 1987-02-12
FI88676B (fi) 1993-03-15
JPS62192322A (ja) 1987-08-22
JPH0788305B2 (ja) 1995-09-27

Similar Documents

Publication Publication Date Title
EP0233849B1 (en) Composition of pregnanolole comprising a stable oil-in-water emulsion
DE3853191T2 (de) Arzneimittelträger.
DE69625213T2 (de) Mikroemulsionen zur verwendung als träger zur verabreichung von wirkstoffen
DE3686221T2 (de) Emulsionen zur parenteralen und/oder oralen verabreichung schwer wasserloeslicher ionisierbarer hydrophober arzneistoffe.
DE69909016T2 (de) Pharmazeutische Zusammensetzung von Estrogen und Progesteron
EP0171084A2 (en) Pharmaceutical oil-in-water type micro-emulsion
DE69924004T2 (de) Verabreichungssystem für wasserunlösliche arzneistoffe
DE3883206T3 (de) Arzneistoff enthaltende fettemulsion des typs "kurz vor gebrauch hergestellt" sowie verfahren zur herstellung einer arzneihaltigen fettemulsion.
JP2019510048A (ja) 週１回又は隔週１回の投与に適したリラグルチドの粘弾性ゲル
DE69525740T2 (de) Spezielle halofantrinhaltige Zusammensetzungen
WO2016124162A1 (zh) 一种丙泮尼地药物组合物及其制备方法
DE2611183C2 (de) Stabilisierte Formulierung prostaglandinartiger Arzneimittel des PGE-Typs
EP0418004B1 (en) Preventive and therapeutic agent for hepatitis
DE69130832T2 (de) Injizierbare amphotericin b enthaltende dispersion
HK101192A (en) Dry substances and stable suspensions
JP2930242B2 (ja) 非経口投与用エマルジヨン
RU2141313C1 (ru) Фармацевтическая эмульсия, содержащая биологически активные стероиды, и способ получения эмульсии
CH673395A5 (cg-RX-API-DMAC10.html)
DE60127140T2 (de) Amphotericin b enthaltende strukturierte emulsion
HU179942B (en) Process for preparing injectable pharmaceutical compositions against internal parasites,particularly for the treatment and prevention of rot of sheep
EP0409936A1 (de) Verfahren zur herstellung wässriger mischmicellösungen.
DE69113391T2 (de) Fettige Emulsion.
JPH0489430A (ja) 低血圧維持剤
DE3411910A1 (de) Galenische zubereitung

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20060129