DE3770830D1 - Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion. - Google Patents

Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion.

Info

Publication number
DE3770830D1
DE3770830D1 DE8787850029T DE3770830T DE3770830D1 DE 3770830 D1 DE3770830 D1 DE 3770830D1 DE 8787850029 T DE8787850029 T DE 8787850029T DE 3770830 T DE3770830 T DE 3770830T DE 3770830 D1 DE3770830 D1 DE 3770830D1
Authority
DE
Germany
Prior art keywords
water emulsion
pregnanolol
preparation
stable oil
pregnanolone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787850029T
Other languages
German (de)
English (en)
Inventor
Roland Ingolf Jeppsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Kabi Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia AB filed Critical Kabi Pharmacia AB
Application granted granted Critical
Publication of DE3770830D1 publication Critical patent/DE3770830D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8787850029T 1986-02-13 1987-01-29 Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion. Expired - Fee Related DE3770830D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8600632A SE8600632D0 (sv) 1986-02-13 1986-02-13 Novel pharmaceutical composition

Publications (1)

Publication Number Publication Date
DE3770830D1 true DE3770830D1 (de) 1991-07-25

Family

ID=20363448

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787850029T Expired - Fee Related DE3770830D1 (de) 1986-02-13 1987-01-29 Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion.

Country Status (14)

Country Link
US (1) US5028600A (cg-RX-API-DMAC10.html)
EP (1) EP0233849B1 (cg-RX-API-DMAC10.html)
JP (1) JPH0788305B2 (cg-RX-API-DMAC10.html)
AT (1) ATE64526T1 (cg-RX-API-DMAC10.html)
CA (1) CA1301651C (cg-RX-API-DMAC10.html)
DE (1) DE3770830D1 (cg-RX-API-DMAC10.html)
DK (1) DK175504B1 (cg-RX-API-DMAC10.html)
ES (1) ES2037742T3 (cg-RX-API-DMAC10.html)
FI (1) FI88676C (cg-RX-API-DMAC10.html)
GR (1) GR3002299T3 (cg-RX-API-DMAC10.html)
HK (1) HK83293A (cg-RX-API-DMAC10.html)
NO (1) NO175040B (cg-RX-API-DMAC10.html)
SE (1) SE8600632D0 (cg-RX-API-DMAC10.html)
SG (1) SG102892G (cg-RX-API-DMAC10.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302295D0 (sv) * 1993-07-02 1993-07-02 Kabi Pharmacia Ab New pharmaceutical composition
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
WO1999007381A1 (en) * 1997-08-11 1999-02-18 Weider Nutrition International, Inc. Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
CA2338703C (en) 1998-08-19 2009-03-24 Rtp Pharma Inc. Injectable aqueous dispersions of propofol
US20020155161A1 (en) * 2000-12-29 2002-10-24 Deckelbaum Richard J. Use of IV emulsions with different triglyceride composition, particle size and apolipoprotein E for targeted tissue delivery of hydrophobic compounds
MXPA04012756A (es) * 2002-07-02 2005-03-23 Altana Pharma Ag Suspension acuosa esteril que contiene ciclesonida.
PE20050941A1 (es) * 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
KR20070058608A (ko) * 2004-09-13 2007-06-08 바라트 쎄럼스 앤드 백신스 리미티드 항미생물 방부 효능을 갖는 정맥 내 투여를 위한 안정한에멀젼 조성물
EP2663326B2 (en) * 2011-01-14 2021-09-29 Vivacelle Bio, Inc. Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
US10478505B2 (en) 2011-09-23 2019-11-19 The Regents Of The University Of California Edible oils to enhance delivery of orally administered steroids
RU2681835C2 (ru) 2012-01-23 2019-03-13 Сейдж Терапьютикс, Инк. Лекарственные формы нейроактивных стероидов и способы лечения нарушений цнс
US20140050789A1 (en) 2012-08-13 2014-02-20 The Regents Of The University Of California Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids
IL294306B2 (en) 2012-08-21 2024-01-01 Sage Therapeutics Inc Methods of treating epilepsy or status epilepticus
AU2013352141B2 (en) 2012-11-30 2018-04-05 The Regents Of The University Of California Anticonvulsant activity of steroids
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
KR20220084418A (ko) 2016-03-08 2022-06-21 세이지 테라퓨틱스, 인크. 신경활성 스테로이드, 조성물, 및 그의 용도
CA3123002A1 (en) * 2018-12-10 2020-06-18 Halo Science LLC Stable formulations of anesthetics and associated dosage forms
CN114269347A (zh) * 2019-08-19 2022-04-01 亚利桑那大学董事会 局部神经类固醇制剂
US11969434B1 (en) 2022-08-29 2024-04-30 Lipocine Inc. Oral allopregnanolone compositions and methods of use
CN114344309B (zh) * 2021-12-30 2024-02-06 南京迈诺威医药科技有限公司 一种别孕烷醇酮衍生物自乳化制剂及其制备方法
US12186327B2 (en) 2022-08-29 2025-01-07 Lipocine Inc. Oral allopregnanolone compositions and methods of use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1215702B (de) * 1962-07-03 1966-05-05 Merck Ag E Verfahren zur Herstellung von 1alpha-Alkylthio-3-keto-androstanen
CA895860A (en) * 1969-11-05 1972-03-21 Kruger Gunther PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXY-5.beta.-PREGNAN-20-ONE
US3900561A (en) * 1970-12-17 1975-08-19 Glaxo Lab Ltd Pharmaceutical compositions
US3917830A (en) * 1970-12-17 1975-11-04 Glaxo Lab Ltd Steroidal anaesthetic composition for intraveneous injection
US4168308A (en) * 1976-03-12 1979-09-18 Apoteksvarucentralen Vitrum Ab Composition for enhancing the administration of pharmacologically active agents
JPS609726B2 (ja) * 1980-05-15 1985-03-12 株式会社 ミドリ十字 ステロイド製剤
JPS5716818A (en) * 1981-04-25 1982-01-28 Green Cross Corp:The Steroid fatty emulsion
JPS60258110A (ja) * 1984-06-05 1985-12-20 Daigo Eiyou Kagaku Kk 静脈注射可能なプロゲステロン乳化注射液

Also Published As

Publication number Publication date
ES2037742T3 (es) 1993-07-01
EP0233849A1 (en) 1987-08-26
FI870589A0 (fi) 1987-02-12
DK62187A (da) 1987-08-14
GR3002299T3 (en) 1992-12-30
US5028600A (en) 1991-07-02
SG102892G (en) 1992-12-04
DK175504B1 (da) 2004-11-15
FI88676C (fi) 1993-06-28
DK62187D0 (da) 1987-02-06
EP0233849B1 (en) 1991-06-19
NO870560L (no) 1987-08-14
HK83293A (en) 1993-08-20
NO175040B (no) 1994-05-16
ATE64526T1 (de) 1991-07-15
NO870560D0 (no) 1987-02-12
NO175040C (cg-RX-API-DMAC10.html) 1994-08-24
JPS62192322A (ja) 1987-08-22
FI88676B (fi) 1993-03-15
SE8600632D0 (sv) 1986-02-13
JPH0788305B2 (ja) 1995-09-27
FI870589L (fi) 1987-08-14
CA1301651C (en) 1992-05-26

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee