ES8502869A1 - Procedimiento para la estabilizacion de preparados farmaceuticos de prostaglandinas. - Google Patents

Procedimiento para la estabilizacion de preparados farmaceuticos de prostaglandinas.

Info

Publication number
ES8502869A1
ES8502869A1 ES500225A ES500225A ES8502869A1 ES 8502869 A1 ES8502869 A1 ES 8502869A1 ES 500225 A ES500225 A ES 500225A ES 500225 A ES500225 A ES 500225A ES 8502869 A1 ES8502869 A1 ES 8502869A1
Authority
ES
Spain
Prior art keywords
blood serum
prostaglandins
stabilizing
stabilization
prostaglandin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES500225A
Other languages
English (en)
Other versions
ES500225A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES500225A0 publication Critical patent/ES500225A0/es
Publication of ES8502869A1 publication Critical patent/ES8502869A1/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA ESTABILIZACION DE PREPATADOS FARMACEUTICOS DE PROSTAGLANDINAS.CONSISTE EN: A) SEPARAR LOS COMPONENTES DE ALTO PESO MOLECULAR DE SUERO SANGUINEO MEDIANTE REACCIONES USUALES DE PRECIPITACION DE PROTEINAS O MEDIANTE EL USO DE TAMICES MOLECULARES; B) RECUPERAR COMO SUSTANCIA ACTIVA, A PARTIR DE LA FRACCION RESTANTE DE BAIO PESO MOLECULAR, UNA FRACCION CON PESO MOLECULAR INFERIOR A 2.000, MEDIANTE LA UTILIZACION REPETIDA DE METODOS CROMATOGRAFICOS; Y C) MEZCLAR LA FRACCION RECUPERADA, COMO ELUATO DE LA CROMATOGRAFIA EN COLUMNA, CON EL PREPARADO ACUOSO DE UNA PROSTAGLANDINA, O BIEN, DESPUES DE LA ELIMINACION DEL AGUA DEL ELUATO POR METODOS USUALES, COMO CONCENTRACION POR EVAPORACION, CONCENTRACION EN EVAPORADOR ROTATORIO O LIOFILIZACION, SE MEZCLA, COMO SUSTANCIA ACTIVA SOLIDA, CON UNA PROSTAGLANDINA SOLIDA, EN PROPORCION 10:1 A 10:1.
ES500225A 1980-03-15 1981-03-10 Procedimiento para la estabilizacion de preparados farmaceuticos de prostaglandinas. Expired ES8502869A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803010002 DE3010002A1 (de) 1980-03-15 1980-03-15 Prostaglandine enthaltende pharmazeutische zubereitung

Publications (2)

Publication Number Publication Date
ES500225A0 ES500225A0 (es) 1985-02-01
ES8502869A1 true ES8502869A1 (es) 1985-02-01

Family

ID=6097308

Family Applications (2)

Application Number Title Priority Date Filing Date
ES500225A Expired ES8502869A1 (es) 1980-03-15 1981-03-10 Procedimiento para la estabilizacion de preparados farmaceuticos de prostaglandinas.
ES510484A Granted ES510484A0 (es) 1980-03-15 1982-03-16 "procedimiento para preparar una sustancia activa adecuada para la estabilizacion de prostaglandinas y sus derivados".

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES510484A Granted ES510484A0 (es) 1980-03-15 1982-03-16 "procedimiento para preparar una sustancia activa adecuada para la estabilizacion de prostaglandinas y sus derivados".

Country Status (9)

Country Link
US (1) US4333948A (es)
EP (1) EP0036514B1 (es)
JP (1) JPS56150018A (es)
AT (1) ATE16809T1 (es)
AU (1) AU545065B2 (es)
CA (1) CA1164343A (es)
DE (2) DE3010002A1 (es)
ES (2) ES8502869A1 (es)
ZA (1) ZA811672B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102832880B (zh) 2011-06-17 2017-03-01 迪尔阿扣基金两合公司 控制转换器的方法
PL2536019T3 (pl) 2011-06-17 2018-06-29 Diehl Ako Stiftung & Co. Kg Sposób sterowania falownikiem

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1535488A (fr) * 1966-04-20 1968-08-09 Behringwerke Ag Substance à bas poids moléculaire et son isolement à partir de fractions sanguines
DE1617510A1 (de) * 1966-04-20 1971-03-11 Wolfgang Dr Med Helmbold Verfahren zur Gewinnung wachstums- und stoffwechselfoerdernder niedermolekularer Substanzen
US4113882A (en) * 1974-10-21 1978-09-12 Yamanouchi Pharmaceutical Co., Ltd. Stabilized oral prostaglandin formulation and the process for the preparation thereof
GB2021581B (en) * 1978-05-17 1982-10-20 Wellcome Found Stabilisation of pgl derivatives
ZA787353B (en) * 1978-05-17 1980-08-27 Wellcome Found Pharmaceutical formulations
US4178454A (en) * 1978-10-11 1979-12-11 Toray Industries, Inc. Stabilized prostaglandin E composition

Also Published As

Publication number Publication date
US4333948A (en) 1982-06-08
ES500225A0 (es) 1985-02-01
CA1164343A (en) 1984-03-27
DE3173084D1 (en) 1986-01-16
ZA811672B (en) 1982-03-31
AU545065B2 (en) 1985-06-27
AU6835881A (en) 1981-09-24
ATE16809T1 (de) 1985-12-15
EP0036514A2 (de) 1981-09-30
JPS56150018A (en) 1981-11-20
EP0036514B1 (de) 1985-12-04
EP0036514A3 (en) 1982-06-09
ES8303324A1 (es) 1983-02-01
ES510484A0 (es) 1983-02-01
DE3010002A1 (de) 1981-10-01

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