HK50388A - Processes for the preparation of an oxo compound, and intermediates required therefor - Google Patents

Processes for the preparation of an oxo compound, and intermediates required therefor Download PDF

Info

Publication number
HK50388A
HK50388A HK503/88A HK50388A HK50388A HK 50388 A HK50388 A HK 50388A HK 503/88 A HK503/88 A HK 503/88A HK 50388 A HK50388 A HK 50388A HK 50388 A HK50388 A HK 50388A
Authority
HK
Hong Kong
Prior art keywords
dibenz
azepine
formula
cyano
compound
Prior art date
Application number
HK503/88A
Other languages
German (de)
English (en)
French (fr)
Inventor
Ernst Dr. Aufderhaar
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK50388A publication Critical patent/HK50388A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
HK503/88A 1979-10-30 1988-07-07 Processes for the preparation of an oxo compound, and intermediates required therefor HK50388A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH970379 1979-10-30

Publications (1)

Publication Number Publication Date
HK50388A true HK50388A (en) 1988-07-15

Family

ID=4354732

Family Applications (1)

Application Number Title Priority Date Filing Date
HK503/88A HK50388A (en) 1979-10-30 1988-07-07 Processes for the preparation of an oxo compound, and intermediates required therefor

Country Status (28)

Country Link
US (4) US4452738A (enExample)
EP (1) EP0028028B1 (enExample)
JP (5) JPS5673067A (enExample)
KR (1) KR850000945B1 (enExample)
AT (1) ATE13426T1 (enExample)
AU (1) AU538069B2 (enExample)
CA (1) CA1163993A (enExample)
CY (1) CY1418A (enExample)
DD (1) DD153835A5 (enExample)
DE (1) DE3070675D1 (enExample)
DK (5) DK163302C (enExample)
ES (1) ES8300708A1 (enExample)
FI (1) FI75561C (enExample)
GR (1) GR71889B (enExample)
HK (1) HK50388A (enExample)
HU (1) HU181208B (enExample)
IE (1) IE50723B1 (enExample)
IL (1) IL61360A (enExample)
KE (1) KE3791A (enExample)
LU (1) LU88347I2 (enExample)
NL (1) NL930105I2 (enExample)
NO (1) NO154725C (enExample)
NZ (1) NZ195395A (enExample)
PL (1) PL227523A1 (enExample)
PT (1) PT71992B (enExample)
SG (1) SG103787G (enExample)
YU (5) YU44318B (enExample)
ZA (1) ZA806643B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2051841T3 (es) * 1987-04-27 1994-07-01 Takeda Chemical Industries Ltd Reduccion de esteres carboxilicos.
US5472714A (en) * 1993-09-08 1995-12-05 Ciba-Geigy Corporation Double-layered oxcarbazepine tablets
PT101732B (pt) * 1995-06-30 1997-12-31 Portela & Ca Sa Novas di-hidrodibenzo<b,f>azepinas substituidas processo para a sua preparacao composicoes farmaceuticas que as contem e utilizacao dos novos compostos na preparacao de composicoes farmaceuticas empregues em doencas do sistema nervoso
PT101876B (pt) * 1996-05-27 1999-09-30 Portela & Ca Sa Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida
US20020022056A1 (en) 1997-02-14 2002-02-21 Burkhard Schlutermann Oxacarbazepine film-coated tablets
CO4920215A1 (es) * 1997-02-14 2000-05-29 Novartis Ag Tabletas de oxacarbazepina recubiertas de una pelicula y metodo para la produccion de estas formulaciones
AT408224B (de) * 1999-03-15 2001-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von oxcarbazepin
IT1317854B1 (it) * 2000-02-25 2003-07-15 Farchemia Srl 5-ciano-10-idrossi-10,11-diidro-5h-dibenz(b,f)azepina e procedimentiper la sua preparazione e per la sua conversione in
ES2211373T1 (es) * 2001-02-12 2004-07-16 Teva Pharmaceutical Industries Ltd. Nuevas formas cristalinas de oxcarbazepina y procedimientos para su preparacion.
CA2471666C (en) 2004-06-18 2009-10-13 Apotex Pharmachem Inc. An improved process for the preparation of oxcarbazepine and related intermediates
US20060252745A1 (en) 2005-05-06 2006-11-09 Almeida Jose L D Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
ES2396051T3 (es) * 2006-04-26 2013-02-18 Supernus Pharmaceuticals, Inc. Preparaciones de liberación controlada de oxcarbazepina que tienen perfil de liberación sigmoidal
CA2658675A1 (en) * 2006-07-24 2008-01-31 Jubilant Organosys Limited Process for producing 10-oxo-10, 11-dihydr0-5h-dibenz [b, f] azepine-5-carboxamide starting from 5-cyanoiminostilbene
GB0700773D0 (en) 2007-01-15 2007-02-21 Portela & Ca Sa Drug therapies
EP2195689A4 (en) * 2007-09-19 2012-05-02 Ravenbrick Llc WINDOW FILMS AND COATINGS WITH LOW EMISSIONS WITH NANOMASS BAR WIRE GRILES
CN100591672C (zh) * 2008-07-04 2010-02-24 浙江工业大学 一种奥卡西平的化学合成方法
WO2013008194A2 (en) 2011-07-13 2013-01-17 Ranbaxy Laboratories Limited Process for the preparation and purification of eslicarbazepine acetate and intermediates thereof
IN2015DN02296A (enExample) 2012-09-26 2015-08-21 Ranbaxy Lab Ltd
CN103288736B (zh) * 2013-02-05 2015-08-05 南京华威医药科技开发有限公司 一种艾司利卡西平中间体的制备方法
ES3053664T3 (en) 2017-09-22 2026-01-23 Unilever Ip Holdings B V Composition comprising vegetable oil and apple cider vinegar

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2762796A (en) * 1956-09-11 Iminodibenzyl derivative
BE597793A (fr) * 1960-12-05 1961-06-05 Geigy Ag J R Nouveaux dérivés de l'azépine et leur préparation.
US3420834A (en) * 1964-11-13 1969-01-07 Roussel Uclaf 2,3-dimethoxy-berbines substituted in the 10 position and process
FR1532301A (fr) * 1967-01-18 1968-07-12 Rhone Poulenc Sa Nouveaux dérivés de la dibenzazépine et leur préparation
CH500196A (de) * 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
NL144275B (nl) * 1969-06-24 1974-12-16 Rhone Poulenc Sa Werkwijze voor de bereiding van fungicide preparaten.
US3637661A (en) * 1970-03-04 1972-01-25 Ciba Geigy Corp 10-hydroxy-10 11-dihydro-dibenzazepine derivative
US4235895A (en) * 1978-11-10 1980-11-25 Ciba-Geigy Corporation Substituted 5H-dibenz[b,f]azepine
JPS5681565A (en) * 1979-10-30 1981-07-03 Ciba Geigy Ag Manufacture of nnheterocyclic compound

Also Published As

Publication number Publication date
US4452738A (en) 1984-06-05
DK99191A (da) 1991-05-24
JPS6445368A (en) 1989-02-17
JPS6445366A (en) 1989-02-17
NL930105I1 (nl) 1993-10-18
JPH0240660B2 (enExample) 1990-09-12
GR71889B (enExample) 1983-08-05
KR830004258A (ko) 1983-07-09
IE50723B1 (en) 1986-06-25
YU45521B (en) 1992-05-28
EP0028028A2 (de) 1981-05-06
DK99391D0 (da) 1991-05-24
JPH0314025B2 (enExample) 1991-02-25
DK99391A (da) 1991-05-24
YU44318B (en) 1990-06-30
IL61360A0 (en) 1980-12-31
DK99291A (da) 1991-05-24
YU136689A (en) 1990-02-28
EP0028028B1 (de) 1985-05-22
KE3791A (en) 1988-03-31
JPH0240662B2 (enExample) 1990-09-12
PT71992B (en) 1981-08-31
YU45522B (en) 1992-05-28
CY1418A (en) 1988-04-22
DK170335B1 (da) 1995-08-07
NO803228L (no) 1981-05-04
YU45520B (en) 1992-05-28
PL227523A1 (enExample) 1981-06-19
ZA806643B (en) 1981-10-28
NO154725B (no) 1986-09-01
IL61360A (en) 1984-04-30
DK99091A (da) 1991-05-24
HU181208B (en) 1983-06-28
ES496333A0 (es) 1982-11-01
FI75561C (fi) 1988-07-11
DE3070675D1 (en) 1985-06-27
JPS6445370A (en) 1989-02-17
US4540514A (en) 1985-09-10
DK99291D0 (da) 1991-05-24
FI803078A7 (fi) 1981-05-01
DK99191D0 (da) 1991-05-24
SG103787G (en) 1988-09-30
YU45519B (en) 1992-05-28
YU137289A (en) 1990-02-21
NO154725C (no) 1986-12-10
YU136489A (en) 1990-02-28
FI75561B (fi) 1988-03-31
ATE13426T1 (de) 1985-06-15
PT71992A (en) 1980-11-01
LU88347I2 (fr) 1994-05-04
JPS6445367A (en) 1989-02-17
JPH0114225B2 (enExample) 1989-03-10
US4559174A (en) 1985-12-17
YU136589A (en) 1990-02-28
JPH0240661B2 (enExample) 1990-09-12
AU538069B2 (en) 1984-07-26
AU6380580A (en) 1981-05-07
ES8300708A1 (es) 1982-11-01
DK163302C (da) 1992-07-06
CA1163993A (en) 1984-03-20
YU277880A (en) 1983-12-31
JPS5673067A (en) 1981-06-17
US4579683A (en) 1986-04-01
DD153835A5 (de) 1982-02-03
KR850000945B1 (ko) 1985-06-29
EP0028028A3 (en) 1981-08-26
NZ195395A (en) 1982-09-14
DK163302B (da) 1992-02-17
DK99091D0 (da) 1991-05-24
NL930105I2 (nl) 1995-02-16
DK457780A (da) 1981-05-01
IE802237L (en) 1981-04-30

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