HK18396A - Cephem compound and a process for preparation thereof - Google Patents

Cephem compound and a process for preparation thereof

Info

Publication number
HK18396A
HK18396A HK18396A HK18396A HK18396A HK 18396 A HK18396 A HK 18396A HK 18396 A HK18396 A HK 18396A HK 18396 A HK18396 A HK 18396A HK 18396 A HK18396 A HK 18396A
Authority
HK
Hong Kong
Prior art keywords
preparation
cephem compound
cephem
compound
Prior art date
Application number
HK18396A
Other languages
English (en)
Inventor
Kazuo Sakane
Kohji Kawabata
Kenzi Miyai
Yoshiko Inamoto
Original Assignee
Fujisawa Pharmceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878721568A external-priority patent/GB8721568D0/en
Priority claimed from GB888815361A external-priority patent/GB8815361D0/en
Application filed by Fujisawa Pharmceutical Co Ltd filed Critical Fujisawa Pharmceutical Co Ltd
Publication of HK18396A publication Critical patent/HK18396A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK18396A 1987-09-14 1996-02-01 Cephem compound and a process for preparation thereof HK18396A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878721568A GB8721568D0 (en) 1987-09-14 1987-09-14 Cephem compounds
GB888815361A GB8815361D0 (en) 1988-06-28 1988-06-28 New cephem compound & process for preparation thereof

Publications (1)

Publication Number Publication Date
HK18396A true HK18396A (en) 1996-02-09

Family

ID=26292732

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18396A HK18396A (en) 1987-09-14 1996-02-01 Cephem compound and a process for preparation thereof

Country Status (22)

Country Link
US (1) US4952578A (fr)
EP (1) EP0307804B1 (fr)
JP (1) JPH01151589A (fr)
KR (1) KR0133560B1 (fr)
CN (1) CN1024669C (fr)
AU (1) AU617358B2 (fr)
CA (1) CA1338842C (fr)
DE (1) DE3885688T2 (fr)
DK (1) DK509988A (fr)
ES (1) ES2061581T3 (fr)
FI (1) FI92322C (fr)
HK (1) HK18396A (fr)
HU (1) HU211830A9 (fr)
IE (1) IE63094B1 (fr)
IL (1) IL87731A (fr)
NO (1) NO171853C (fr)
NZ (1) NZ226143A (fr)
OA (1) OA09014A (fr)
PH (1) PH24719A (fr)
PT (1) PT88481B (fr)
RU (1) RU1787158C (fr)
UA (1) UA41865C2 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194432A (en) * 1985-11-22 1993-03-16 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US5162520A (en) * 1986-09-22 1992-11-10 Fujisawa Pharmaceutical Co., Ltd. Intermediates for cephem compounds
CA1293719C (fr) * 1986-09-22 1991-12-31 Takao Takaya Composes de cephem et procede de preparation
US5663163A (en) * 1987-09-07 1997-09-02 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
GB8905301D0 (en) * 1989-03-08 1989-04-19 Fujisawa Pharmaceutical Co New cephem compound and a process for preparation thereof
EP0517041A1 (fr) * 1991-06-07 1992-12-09 Fujisawa Pharmaceutical Co., Ltd. Dérivés céphem
ES2254671T3 (es) * 2001-05-01 2006-06-16 Astellas Pharma Inc. Compuestos de cefem.
KR100463920B1 (ko) * 2002-10-18 2004-12-30 제일약품주식회사 신규 세프디토렌 피복실 메지틸렌 설폰산염 및 그 제조방법
DK1556389T6 (da) * 2002-10-30 2015-05-11 Astellas Pharma Inc Cephemforbindelser
AU2003902380A0 (en) * 2003-05-16 2003-06-05 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
MXPA06003068A (es) * 2003-09-18 2006-08-25 Astellas Pharma Inc Compuestos de cefem.
CN1321109C (zh) * 2003-11-07 2007-06-13 天津药物研究院 一种头孢烯类鎓盐化合物及其制备方法和以该化合物合成硫酸头孢吡唑的方法
CN101747348B (zh) * 2008-12-11 2013-02-06 石药集团中奇制药技术（石家庄）有限公司 一种硫酸头孢噻利晶型及其制备方法
CN101781318B (zh) * 2010-02-26 2013-07-31 烟台宝华生物技术有限公司 头孢母核衍生化合物、由其制备的头孢烯类鎓盐化合物及采用其制备硫酸头孢吡唑的方法
CN101830913B (zh) * 2010-04-09 2012-10-31 烟台宝华生物技术有限公司 头孢母核衍生化合物、由其制备的头孢烯类鎓盐化合物及采用其制备硫酸头孢吡唑的方法
CN101993450B (zh) * 2010-11-03 2011-11-30 湖南欧亚生物有限公司 一种硫酸头孢噻利的制备方法
CN102336771A (zh) * 2011-07-11 2012-02-01 珠海联邦制药股份有限公司 一种硫酸头孢噻利中间体的制备方法
EP2862569A1 (fr) 2011-09-09 2015-04-22 Cubist Pharmaceuticals, Inc. Procédés pour traiter des infections intrapulmonaires
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
CN102875572B (zh) * 2012-10-26 2014-07-30 四川科伦药物研究有限公司 一种硫酸头孢噻利中间体的精制方法
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
EP2893929A1 (fr) 2013-03-15 2015-07-15 Cubist Pharmaceuticals, Inc. Compositions antibiotiques à base de ceftolozane
US20140275000A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
WO2015035376A2 (fr) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Traitement d'infections au moyen de ceftolozane/tazobactam chez des sujets ayant une fonction rénale altérée
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
GB2037281B (en) * 1978-11-15 1983-01-19 Glaxo Group Ltd 7( -(2-amino-4-thiozolyl)-2-hydroximino-acetanuds)-cephalosporins
DE3279470D1 (en) * 1981-04-03 1989-04-06 Fujisawa Pharmaceutical Co New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds
JPS584789A (ja) * 1981-04-03 1983-01-11 Fujisawa Pharmaceut Co Ltd 新規セフエム化合物およびその製造法
US4401668A (en) * 1981-10-02 1983-08-30 Eli Lilly And Company Pyrazinium substituted cephalosporins
DE3687200T2 (de) * 1985-09-03 1993-05-27 Otsuka Kagaku Kk Cephalosporinderivate.
DE3539901A1 (de) * 1985-11-11 1987-05-14 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
CN86107947A (zh) * 1985-11-22 1987-05-27 藤沢药品工业株式会社 新的头孢烯化合物及其制备方法

Also Published As

Publication number Publication date
US4952578A (en) 1990-08-28
JPH0576950B2 (fr) 1993-10-25
PH24719A (en) 1990-10-01
FI92322C (fi) 1994-10-25
FI884193A0 (fi) 1988-09-13
NO884058L (no) 1989-03-15
NO171853B (no) 1993-02-01
DK509988D0 (da) 1988-09-13
ES2061581T3 (es) 1994-12-16
IL87731A (en) 1993-05-13
IL87731A0 (en) 1989-02-28
IE63094B1 (en) 1995-03-22
EP0307804A3 (en) 1989-11-08
HU211830A9 (en) 1995-12-28
KR0133560B1 (ko) 1998-04-23
KR890005124A (ko) 1989-05-11
DK509988A (da) 1989-03-15
NO884058D0 (no) 1988-09-13
NO171853C (no) 1993-05-12
PT88481A (pt) 1988-10-01
DE3885688D1 (de) 1993-12-23
AU2227188A (en) 1989-03-16
IE882692L (en) 1989-03-14
UA41865C2 (uk) 2001-10-15
NZ226143A (en) 1990-11-27
CA1338842C (fr) 1997-01-14
CN1024669C (zh) 1994-05-25
FI92322B (fi) 1994-07-15
OA09014A (fr) 1991-03-31
DE3885688T2 (de) 1994-04-07
EP0307804A2 (fr) 1989-03-22
JPH01151589A (ja) 1989-06-14
PT88481B (pt) 1992-11-30
FI884193A (fi) 1989-03-15
AU617358B2 (en) 1991-11-28
CN1032540A (zh) 1989-04-26
RU1787158C (ru) 1993-01-07
EP0307804B1 (fr) 1993-11-18

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)