HK1247911A1 - 多環化合物及其使用方法 - Google Patents
多環化合物及其使用方法Info
- Publication number
- HK1247911A1 HK1247911A1 HK18107195.8A HK18107195A HK1247911A1 HK 1247911 A1 HK1247911 A1 HK 1247911A1 HK 18107195 A HK18107195 A HK 18107195A HK 1247911 A1 HK1247911 A1 HK 1247911A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- multicyclic compounds
- multicyclic
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C—CHEMISTRY; METALLURGY
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
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- C07D277/62—Benzothiazoles
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- C07D277/82—Nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/76—Dibenzothiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/20—Spiro-condensed systems
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26688009P | 2009-12-04 | 2009-12-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1247911A1 true HK1247911A1 (zh) | 2018-10-05 |
Family
ID=44115515
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15105471.0A HK1212969A1 (zh) | 2009-12-04 | 2015-06-09 | 多環化合物及其使用方法 |
HK18107195.8A HK1247911A1 (zh) | 2009-12-04 | 2018-05-31 | 多環化合物及其使用方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15105471.0A HK1212969A1 (zh) | 2009-12-04 | 2015-06-09 | 多環化合物及其使用方法 |
Country Status (19)
Country | Link |
---|---|
US (7) | US8710245B2 (zh) |
EP (2) | EP2507245B1 (zh) |
JP (7) | JP5778168B2 (zh) |
KR (7) | KR102307413B1 (zh) |
CN (4) | CN102762575B (zh) |
AU (3) | AU2010325925B2 (zh) |
BR (2) | BR122021013836B1 (zh) |
CA (1) | CA2781716A1 (zh) |
DK (1) | DK2507245T3 (zh) |
ES (1) | ES2625330T3 (zh) |
HK (2) | HK1212969A1 (zh) |
IL (6) | IL272376B1 (zh) |
MX (2) | MX2012006326A (zh) |
NZ (5) | NZ731621A (zh) |
PT (1) | PT2507245T (zh) |
RU (3) | RU2557059C2 (zh) |
SG (3) | SG10201401661RA (zh) |
WO (1) | WO2011069063A2 (zh) |
ZA (1) | ZA201203533B (zh) |
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CN102762575B (zh) * | 2009-12-04 | 2015-04-15 | 桑诺维恩药品公司 | 多环化合物及其使用方法 |
WO2013066152A1 (en) * | 2011-10-31 | 2013-05-10 | N.V. Nutricia | Method for improving executive function |
US10189825B2 (en) * | 2012-02-08 | 2019-01-29 | Sunovion Pharmaceuticals Inc. | Heteroaryl compounds and methods of use thereof |
CN103755727B (zh) * | 2013-12-20 | 2015-12-30 | 南京华威医药科技开发有限公司 | 布林佐胺中间体制备方法 |
EP3096755A4 (en) * | 2014-01-23 | 2017-12-27 | Sova Pharmaceuticals, Inc. | CYSTATHIONINE-(gamma)-LYASE (CSE) INHIBITORS FOR TREATING PAIN |
CN104193722A (zh) * | 2014-08-27 | 2014-12-10 | 湖南华腾制药有限公司 | 一种n-叔丁氧羰基-3-甲胺噻吩的制备方法 |
MA48048A (fr) | 2014-08-27 | 2020-02-12 | Prexton Therapeutics Sa | Nouveau dérivé d'oxime de chromone et son utilisation comme modulateur allostérique de récepteurs métabotropiques du glutamate |
MX371404B (es) * | 2015-02-11 | 2020-01-29 | Sunovion Pharmaceuticals Inc | Compuestos y analogos de 1-heterociclil isocromanilo para el tratamiento de trastornos del sistema nervioso central (snc). |
BR112017017349B1 (pt) * | 2015-02-11 | 2024-01-23 | Pgi Drug Discovery Llc | Composto e seu uso, composição, processo para preparar um composto e processo para separar um composto |
EP3341380B1 (en) | 2015-08-27 | 2019-11-13 | Prexton Therapeutics SA | Brain-penetrant chromone oxime derivative for the therapy of levodopa-induced dyskinesia |
AR105821A1 (es) * | 2015-09-09 | 2017-11-15 | Lilly Co Eli | COMPUESTOS ÚTILES PARA INHIBIR ROR-g-T |
EP3407888B1 (en) * | 2016-01-26 | 2020-12-30 | Intra-Cellular Therapies, Inc. | Pyridopyrroloquinoxaline compounds, their compositions and uses |
WO2017144341A1 (de) | 2016-02-23 | 2017-08-31 | Bayer Cropscience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
CN116283877A (zh) | 2016-07-29 | 2023-06-23 | 赛诺维信制药公司 | 化合物、组合物及其用途 |
EA201990399A1 (ru) | 2016-07-29 | 2019-07-31 | Суновион Фармасьютикалз, Инк. | Соединения, композиции и их применение |
US11129807B2 (en) * | 2017-02-16 | 2021-09-28 | Sunovion Pharmaceuticals Inc. | Methods of treating schizophrenia |
WO2018166855A1 (en) | 2017-03-16 | 2018-09-20 | Basf Se | Heterobicyclic substituted dihydroisoxazoles |
EA202090414A1 (ru) | 2017-08-02 | 2020-05-28 | Суновион Фармасьютикалз Инк. | Соединения и их применение |
CA3091292A1 (en) * | 2018-02-16 | 2019-08-22 | Sunovion Pharmaceuticals Inc. | Salts, crystal forms, and production methods thereof |
US20210008030A1 (en) * | 2018-02-16 | 2021-01-14 | Sunovion Pharmaceuticals Inc. | Methods of treating social function disorders |
CA3122261A1 (en) | 2018-12-06 | 2020-06-11 | Sunovion Pharmaceuticals Inc. | Methods of treating neurological and psychiatric disorders |
AU2020236225A1 (en) | 2019-03-14 | 2021-09-16 | Sunovion Pharmaceuticals Inc. | Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
CN110894195A (zh) * | 2019-12-09 | 2020-03-20 | 门希国 | 一种新的2-噻吩乙酸的制备新方法 |
US20230147129A1 (en) | 2020-03-27 | 2023-05-11 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of synucleinopathies |
MX2022012833A (es) | 2020-04-14 | 2022-11-07 | Sunovion Pharmaceuticals Inc | (s)-(4,5-dihidro-7h-tieno[2,3-c]piran-7-il)-n-metilmetanamina para tratar trastornos neurologicos y psiquiatricos. |
WO2022060758A1 (en) * | 2020-09-16 | 2022-03-24 | Teva Pharmaceuticals International Gmbh | Solid state forms of sep-363856 and process for preparation thereof |
EP4317164A1 (en) * | 2021-03-29 | 2024-02-07 | Shujing Biopharma Co., Ltd | Spiro-containing derivative, and preparation method therefor and use thereof |
JPWO2022215754A1 (zh) * | 2021-04-10 | 2022-10-13 | ||
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WO2023078392A1 (zh) * | 2021-11-04 | 2023-05-11 | 上海翰森生物医药科技有限公司 | 2-(芳基-2-基)吗啉及其氘代衍生物、制备方法和应用 |
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WO2023246872A1 (zh) * | 2022-06-24 | 2023-12-28 | 山东绿叶制药有限公司 | 作为taar1配体激动剂的杂环化合物 |
WO2024050323A1 (en) | 2022-08-30 | 2024-03-07 | Sunovion Pharmaceuticals Inc. | Ulotaront for the adjuvant treatment of major depressive disorder |
WO2024067542A1 (zh) * | 2022-09-27 | 2024-04-04 | 上海枢境生物科技有限公司 | 一种含螺环类衍生物的盐、晶型及其制备方法和应用 |
WO2024081828A1 (en) | 2022-10-13 | 2024-04-18 | Sunovion Pharmaceuticals Inc. | Methods of reducing physical dependence to neuropsychiatric treatments |
CN115677719A (zh) * | 2022-10-27 | 2023-02-03 | 复旦大学 | 一种芳基并杂环化合物及其制备方法和用途 |
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