HK1209134A1 - Non-natural consensus albumin binding domains - Google Patents

Non-natural consensus albumin binding domains

Info

Publication number
HK1209134A1
HK1209134A1 HK15109729.2A HK15109729A HK1209134A1 HK 1209134 A1 HK1209134 A1 HK 1209134A1 HK 15109729 A HK15109729 A HK 15109729A HK 1209134 A1 HK1209134 A1 HK 1209134A1
Authority
HK
Hong Kong
Prior art keywords
binding domains
albumin binding
natural consensus
consensus albumin
natural
Prior art date
Application number
HK15109729.2A
Other languages
English (en)
Chinese (zh)
Inventor
Steven Jacobs
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of HK1209134A1 publication Critical patent/HK1209134A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15109729.2A 2012-05-25 2015-10-06 Non-natural consensus albumin binding domains HK1209134A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261651642P 2012-05-25 2012-05-25
US201361776918P 2013-03-12 2013-03-12
PCT/US2013/042429 WO2013177398A2 (fr) 2012-05-25 2013-05-23 Domaines consensus non endogènes de liaison à l'albumine

Publications (1)

Publication Number Publication Date
HK1209134A1 true HK1209134A1 (en) 2016-03-24

Family

ID=49622071

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109729.2A HK1209134A1 (en) 2012-05-25 2015-10-06 Non-natural consensus albumin binding domains

Country Status (16)

Country Link
US (3) US9156887B2 (fr)
EP (1) EP2855509B1 (fr)
JP (3) JP2015519345A (fr)
KR (1) KR102053674B1 (fr)
CN (1) CN104470944B (fr)
AU (2) AU2013266215B2 (fr)
BR (1) BR112014029409B1 (fr)
CA (1) CA2874646C (fr)
DK (1) DK2855509T3 (fr)
EA (1) EA036487B1 (fr)
ES (1) ES2670442T3 (fr)
HK (1) HK1209134A1 (fr)
IL (2) IL235808A (fr)
MX (1) MX355041B (fr)
PT (1) PT2855509T (fr)
WO (1) WO2013177398A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9695228B2 (en) 2012-11-21 2017-07-04 Janssen Biotech, Inc. EGFR and c-Met fibronectin type III domain binding molecules
WO2014140882A2 (fr) * 2013-03-14 2014-09-18 The Governing Council Of The University Of Toronto Banques peptidiques à base d'un échafaudage et leurs procédés d'élaboration et de criblage
JP2018518945A (ja) * 2015-04-29 2018-07-19 メディオラヌム・ファルマチェウティチ・ソチエタ・ペル・アツィオーニ 可溶性キメラインターロイキン−10受容体およびその療法使用
US10456442B2 (en) * 2015-06-18 2019-10-29 Albert Einstein College Of Medicine FGF receptor ligands for treating diabetes and obesity
CN106699842B (zh) * 2015-11-17 2020-06-12 上海交通大学 一种新的抗炎小分子多肽及其应用
CA3054286A1 (fr) 2016-03-01 2017-09-08 The Board Of Trustees Of The University Of Illinois Variants et proteines de fusion de l-asparaginase ayant une activite l-glutaminase reduite et une stabilite amelioree
CA3046963A1 (fr) 2016-12-14 2018-06-21 Janssen Biotech, Inc. Domaines de fibronectine de type iii se liant a cd8a
WO2018111978A1 (fr) 2016-12-14 2018-06-21 Janssen Biotech, Inc. Domaines de fibronectine de type iii à liaison au cd137
US10443049B2 (en) * 2017-01-24 2019-10-15 Northwestern University Active low molecular weight variants of angiotensin converting enzyme 2 (ACE2)
AU2018313253B2 (en) 2017-08-11 2024-09-26 The Board Of Trustees Of The University Of Illinois Truncated guinea pig L-asparaginase variants and methods of use
JP7545894B2 (ja) 2018-03-13 2024-09-05 アフィボディ アクティエボラーグ 新規足場に基づくポリペプチド
KR102282240B1 (ko) * 2018-12-06 2021-07-28 경상국립대학교산학협력단 지속형 엑센딘-4 및 이의 용도
US11781138B2 (en) 2019-10-14 2023-10-10 Aro Biotherapeutics Company FN3 domain-siRNA conjugates and uses thereof
WO2021076546A1 (fr) 2019-10-14 2021-04-22 Aro Biotherapeutics Company Domaines de type iii de fibronectine de liaison à cd137
AU2020405107A1 (en) * 2019-12-18 2022-07-14 Aro Biotherapeutics Company Serum albumin-binding fibronectin type III domains and uses thereof
BR112023021325A2 (pt) 2021-04-14 2023-12-19 Aro Biotherapeutics Company Domínios de fibronectina tipo iii de ligação a cd71
CN113336860B (zh) * 2021-06-02 2022-07-01 北京大学 一种具有靶向和长效功能的重组水蛭素融合蛋白及其编码基因和应用
WO2024102190A2 (fr) * 2022-11-09 2024-05-16 Avitide LLC Agents d'affinité
WO2024130179A1 (fr) 2022-12-16 2024-06-20 Repertoire Immune Medicines, Inc. Récepteurs de lymphocytes t se liant à des épitopes de hpv-16

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6267964B1 (en) 1989-08-01 2001-07-31 Affibody Technology Sweden Ab Stabilized protein or peptide conjugates able to bond albumin having extended biological half-lives
DK0640135T3 (da) * 1992-05-07 2001-02-05 Affitech As Immunoglobulinbindende proteiner, der er afledt af protein L, og anvendelser af disse
AU5670194A (en) 1992-11-20 1994-06-22 Enzon, Inc. Linker for linked fusion polypeptides
ES2340857T3 (es) 1997-09-16 2010-06-10 Centocor Ortho Biotech Inc. Metodo para la sintesis quimica completa y emsamblaje de genes y genomas.
US6670127B2 (en) 1997-09-16 2003-12-30 Egea Biosciences, Inc. Method for assembly of a polynucleotide encoding a target polypeptide
US20050287153A1 (en) 2002-06-28 2005-12-29 Genentech, Inc. Serum albumin binding peptides for tumor targeting
PT1240337E (pt) 1999-12-24 2007-01-31 Genentech Inc Métodos e composições para prolongar as meias-vidas de eliminação de compostos bioactivos
EP2190863B1 (fr) 2007-07-31 2015-09-02 Affibody AB Nouvelles compositions, nouveaux procédés et nouvelles utilisations
WO2010001908A1 (fr) 2008-06-30 2010-01-07 協和発酵キリン株式会社 Anticorps anti-cd27
AU2009308935B2 (en) * 2008-10-31 2015-02-26 Janssen Biotech, Inc. Fibronectin type III domain based scaffold compositions, methods and uses
JP5557254B2 (ja) * 2009-02-10 2014-07-23 国立大学法人 琉球大学 薬物運搬体並びにこれを利用したアジュバントおよびワクチン
JP5873335B2 (ja) 2009-02-12 2016-03-01 ヤンセン バイオテツク,インコーポレーテツド フィブロネクチンiii型ドメインに基づくスカフォールド組成物、方法及び使用
ES2548030T3 (es) * 2009-06-01 2015-10-13 Medimmune, Llc Moléculas con semividas prolongadas y usos de las mismas
WO2011130434A2 (fr) 2010-04-13 2011-10-20 Celldex Therapeutics Inc. Anticorps qui se lient au cd27 humain et utilisations de ceux-ci
PT2571531T (pt) * 2010-04-30 2016-08-31 Janssen Biotech Inc Composições do domínio da fibronectina estabilizadas, métodos e utilizações
US9695228B2 (en) * 2012-11-21 2017-07-04 Janssen Biotech, Inc. EGFR and c-Met fibronectin type III domain binding molecules

Also Published As

Publication number Publication date
MX2014014384A (es) 2015-05-11
CA2874646C (fr) 2020-12-01
IL254652A0 (en) 2017-11-30
KR102053674B1 (ko) 2019-12-09
US20180009854A1 (en) 2018-01-11
IL235808A (en) 2017-10-31
EP2855509A2 (fr) 2015-04-08
ES2670442T3 (es) 2018-05-30
JP7166081B2 (ja) 2022-11-07
CA2874646A1 (fr) 2013-11-28
AU2013266215A1 (en) 2014-12-04
CN104470944B (zh) 2021-09-14
IL254652B (en) 2019-12-31
JP2021019595A (ja) 2021-02-18
EA201590136A1 (ru) 2016-02-29
WO2013177398A2 (fr) 2013-11-28
IL235808A0 (en) 2015-01-29
AU2017261625B2 (en) 2019-11-21
US10280200B2 (en) 2019-05-07
EP2855509A4 (fr) 2016-01-13
WO2013177398A3 (fr) 2014-03-27
EA036487B1 (ru) 2020-11-16
CN104470944A (zh) 2015-03-25
US20160083436A1 (en) 2016-03-24
US9156887B2 (en) 2015-10-13
BR112014029409B1 (pt) 2022-11-29
US20130316952A1 (en) 2013-11-28
DK2855509T3 (en) 2018-07-23
KR20150016585A (ko) 2015-02-12
JP2018171063A (ja) 2018-11-08
EP2855509B1 (fr) 2018-05-02
MX355041B (es) 2018-03-28
PT2855509T (pt) 2018-08-03
AU2017261625A1 (en) 2017-12-07
AU2013266215B2 (en) 2017-12-07
JP2015519345A (ja) 2015-07-09
BR112014029409A2 (fr) 2017-08-15

Similar Documents

Publication Publication Date Title
IL254652B (en) Unnatural albumin binding sites
HK1211297A1 (en) Binding proteins comprising at least two repeat domains against her2 her2
HK1208707A1 (en) Cd3 binding polypeptides cd3
ME03796B (fr) Protéines de liaison anti-lag-3
HK1207656A1 (en) Albumin binding polypeptide
IL233793A0 (en) mica binders
GB2506862B (en) Book
PL2912054T3 (pl) Polipeptyd wiążący albuminę
HK1205524A1 (en) Engineered conformationally-stabilized proteins
EP2793918A4 (fr) Peptides de liaison à hdc-sign
HK1204948A1 (en) Radiation-sterilization-resistant protein composition
GB201418608D0 (en) Peridinin-chlorophyll binding proteins
GB201213672D0 (en) Protein
GB201200563D0 (en) Binding molecule
HK1211952A1 (en) Recombinant protein
GB201203944D0 (en) Binding polypeptides
GB201214293D0 (en) Binding surfaces
GB201215901D0 (en) Protein modification
GB201200743D0 (en) Protein bridges
GB201103961D0 (en) Binding polypeptides
GB201217550D0 (en) Stoarage book
GB201200679D0 (en) Document binding system