HK1208365A1 - 包括二脫水半乳糖醇和類似物的經取代的己糖醇類於治療包括多形性膠質母細胞瘤和成神經管細胞瘤的腫瘤疾病和癌症幹細胞的用途 - Google Patents

包括二脫水半乳糖醇和類似物的經取代的己糖醇類於治療包括多形性膠質母細胞瘤和成神經管細胞瘤的腫瘤疾病和癌症幹細胞的用途

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Publication number
HK1208365A1
HK1208365A1 HK15109103.8A HK15109103A HK1208365A1 HK 1208365 A1 HK1208365 A1 HK 1208365A1 HK 15109103 A HK15109103 A HK 15109103A HK 1208365 A1 HK1208365 A1 HK 1208365A1
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HK
Hong Kong
Prior art keywords
multforme
medulloblastoma
analogs
stem cells
cancer stem
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HK15109103.8A
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English (en)
Inventor
．巴沙
．杜恩
．布朗
Original Assignee
Brown Ennis
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48799821&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1208365(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Brown Ennis filed Critical Brown Ennis
Publication of HK1208365A1 publication Critical patent/HK1208365A1/zh

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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HK15109103.8A 2012-01-20 2015-09-17 包括二脫水半乳糖醇和類似物的經取代的己糖醇類於治療包括多形性膠質母細胞瘤和成神經管細胞瘤的腫瘤疾病和癌症幹細胞的用途 HK1208365A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261589029P 2012-01-20 2012-01-20
PCT/US2013/022505 WO2013110058A2 (en) 2012-01-20 2013-01-22 Use of substituted hexitols including dianhydrogalactitol and analogs to treat neoplastic disease and cancer stem cells including glioblastoma multforme and medulloblastoma

Publications (1)

Publication Number Publication Date
HK1208365A1 true HK1208365A1 (zh) 2016-03-04

Family

ID=48799821

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109103.8A HK1208365A1 (zh) 2012-01-20 2015-09-17 包括二脫水半乳糖醇和類似物的經取代的己糖醇類於治療包括多形性膠質母細胞瘤和成神經管細胞瘤的腫瘤疾病和癌症幹細胞的用途

Country Status (14)

Country Link
US (6) US10201521B2 (zh)
EP (1) EP2804602A4 (zh)
JP (4) JP2015511936A (zh)
KR (3) KR20220137154A (zh)
CN (4) CN110711188A (zh)
AU (3) AU2013209394A1 (zh)
BR (1) BR112014017833A2 (zh)
CA (1) CA2862706C (zh)
CL (1) CL2014001917A1 (zh)
HK (1) HK1208365A1 (zh)
IL (2) IL233722B (zh)
MX (2) MX367614B (zh)
SG (1) SG11201404216TA (zh)
WO (1) WO2013110058A2 (zh)

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WO2013110058A2 (en) * 2012-01-20 2013-07-25 Bacha Jeffrey Use of substituted hexitols including dianhydrogalactitol and analogs to treat neoplastic disease and cancer stem cells including glioblastoma multforme and medulloblastoma
JP2016519684A (ja) * 2013-04-08 2016-07-07 デニス エム ブラウン 準最適に投与された薬物療法の有効性を改善するための及び／又は副作用を低減するための方法および組成物
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US20160067241A1 (en) * 2013-06-13 2016-03-10 Dennis M. Brown Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted naphthalimides such as amonafide for the treatment of immunological, metabolic, infectious, and benign or neoplastic hyperproliferative disease conditions
KR102359214B1 (ko) * 2014-04-04 2022-02-07 델 마 파마슈티컬스 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체
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US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
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US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US10654783B2 (en) * 2015-06-16 2020-05-19 Targent, Llc Crystalline polymorphs of 1,6-dibromo-1,6-dideoxy-dulcitol
WO2017042634A2 (en) * 2015-09-10 2017-03-16 Del Mar Pharmaceuticals Use of dianhydrogalactitol or derivatives and analogs thereof for treatment of non-small-cell lung carcinoma, glioblastoma, and ovarian carcinoma by induction of dna damage and stalling of cell cycle
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CN105663076A (zh) * 2016-02-23 2016-06-15 广西梧州制药（集团）股份有限公司 一种起效快防潮好的去水卫矛醇薄膜包衣片及其制备方法
CN105663075B (zh) * 2016-02-23 2018-09-14 广西梧州制药（集团）股份有限公司 一种二溴卫矛醇肠溶片及其制备方法
CN105663060B (zh) * 2016-02-23 2018-08-14 广西梧州制药（集团）股份有限公司 一种去水卫矛醇脂质体冻干粉针剂及其制备方法
CN105663072B (zh) * 2016-02-23 2018-09-28 广西梧州制药（集团）股份有限公司 一种去水卫矛醇薄膜包衣片及其制备方法
US20190133980A1 (en) * 2016-06-02 2019-05-09 Yale University Compositions and methods for targeting and treating homologous recombination-deficient tumors
WO2018204412A1 (en) * 2017-05-01 2018-11-08 Thomas Jefferson University Systems-level analysis of tcga cancers reveals disease trna fragmentation patterns and associations with messenger rnas and repeat
US20200062839A1 (en) * 2017-05-01 2020-02-27 Del Mar Pharmaceuticals (Bc) Ltd. Use of dianhydrogalactitol or analogs and derivatives in combination with vegf inhibitors to treat cancer
KR20200055722A (ko) 2017-09-20 2020-05-21 오클라호마 메디컬 리써치 화운데이션 약물 내성 신경아교종의 치료
US11717505B2 (en) 2017-12-01 2023-08-08 Del Mar Pharmaceuticals (Bc) Limited Dianhydrogalactitol for the treatment of diffuse intrinsic pontine gliomas
CN112236140A (zh) * 2018-02-12 2021-01-15 美迪诺亚公司 用于癌症治疗的使用异丁司特和第二药剂的方法和剂量方案
US11311538B2 (en) 2018-07-13 2022-04-26 Yale University Compositions and methods for targeting cancers
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