HK1206066A1 - 抗生素藥敏性的快速測試 - Google Patents

抗生素藥敏性的快速測試

Info

Publication number
HK1206066A1
HK1206066A1 HK15106373.7A HK15106373A HK1206066A1 HK 1206066 A1 HK1206066 A1 HK 1206066A1 HK 15106373 A HK15106373 A HK 15106373A HK 1206066 A1 HK1206066 A1 HK 1206066A1
Authority
HK
Hong Kong
Prior art keywords
susceptibility testing
antibiotic susceptibility
rapid antibiotic
rapid
testing
Prior art date
Application number
HK15106373.7A
Other languages
English (en)
Inventor
Michael Super
Donald E Ingber
Mark J Cartwright
Alexander Watters
John Samuel Workman
Daniel Levner
Martin Rottman
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of HK1206066A1 publication Critical patent/HK1206066A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56916—Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/24—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • G01N2333/245—Escherichia (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/305—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F)
    • G01N2333/31—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK15106373.7A 2012-02-29 2015-07-03 抗生素藥敏性的快速測試 HK1206066A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261604878P 2012-02-29 2012-02-29
US201261647860P 2012-05-16 2012-05-16
PCT/US2013/028409 WO2013130875A1 (en) 2012-02-29 2013-02-28 Rapid antibiotic susceptibility testing

Publications (1)

Publication Number Publication Date
HK1206066A1 true HK1206066A1 (zh) 2015-12-31

Family

ID=49083304

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15106373.7A HK1206066A1 (zh) 2012-02-29 2015-07-03 抗生素藥敏性的快速測試

Country Status (7)

Country Link
US (1) US9632085B2 (zh)
EP (1) EP2820147B1 (zh)
CN (1) CN104284984B (zh)
AU (1) AU2013225823A1 (zh)
CA (1) CA2865744A1 (zh)
HK (1) HK1206066A1 (zh)
WO (1) WO2013130875A1 (zh)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005027714A2 (en) 2003-07-12 2005-03-31 Accelr8 Technology Corporation Sensitive and rapid biodetection
US10254204B2 (en) 2011-03-07 2019-04-09 Accelerate Diagnostics, Inc. Membrane-assisted purification
EP2683831B1 (en) 2011-03-07 2015-09-23 Accelerate Diagnostics, Inc. Rapid cell purification systems
US9562253B1 (en) 2012-11-09 2017-02-07 Point Of Care Diagnostics, Llc Distinguishing between a bacterial and non-bacterial infection at the point of care
US10551379B2 (en) 2013-03-15 2020-02-04 President And Fellows Of Harvard College Methods and compositions for improving detection and/or capture of a target entity
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
AU2014268603B2 (en) 2013-05-21 2018-03-22 President And Fellows Of Harvard College Engineered heme-binding compositions and uses thereof
US9791440B2 (en) 2013-07-15 2017-10-17 President And Fellows Of Harvard College Assays for antimicrobial activity and applications thereof
EP3912986B1 (en) * 2013-12-18 2023-12-13 President and Fellows of Harvard College Crp capture/detection of bacteria
DE102014206140A1 (de) 2014-04-01 2015-10-01 Robert Bosch Gmbh Mikrofluidische Vorrichtung und Verfahren zum Analysieren einer Probe biologischen Materials
CA2946721C (en) * 2014-04-24 2022-10-25 Point Of Care Diagnostics, Llc Rapid determination of bacterial susceptibility to an antibiotic at the point of care
WO2016077067A2 (en) * 2014-10-27 2016-05-19 President And Fellows Of Harvard College Magnetic capture of a target from a fluid
US11542545B2 (en) 2014-11-05 2023-01-03 California Institute Of Technology Microfluidic measurements of the response of an organism to a drug
CN107646089B (zh) 2015-03-06 2020-12-08 英国质谱公司 光谱分析
CN108700590B (zh) 2015-03-06 2021-03-02 英国质谱公司 细胞群体分析
EP3726562B1 (en) 2015-03-06 2023-12-20 Micromass UK Limited Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue
EP3265820B1 (en) 2015-03-06 2023-12-13 Micromass UK Limited Spectrometric analysis of microbes
WO2016142685A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Collision surface for improved ionisation
US10026599B2 (en) 2015-03-06 2018-07-17 Micromass Uk Limited Rapid evaporative ionisation mass spectrometry (“REIMS”) and desorption electrospray ionisation mass spectrometry (“DESI-MS”) analysis of swabs and biopsy samples
US11289320B2 (en) 2015-03-06 2022-03-29 Micromass Uk Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
KR102092047B1 (ko) 2015-03-06 2020-03-24 마이크로매스 유케이 리미티드 생체내 내시경 조직 식별 도구
CN104744702B (zh) * 2015-03-26 2016-01-20 华中农业大学 牛血清白蛋白表面分子印迹聚合物及其制备方法
AU2016243656A1 (en) 2015-03-30 2017-11-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
US11071526B2 (en) 2015-04-29 2021-07-27 Perkinelmer Health Sciences, Inc. Specimen collection and delivery apparatus
US20180291364A1 (en) * 2015-05-08 2018-10-11 Biomagnetic Solutions Llc. Apparatus and method for immunomagnetic cell separation
FR3038915B1 (fr) * 2015-07-15 2019-05-17 Universite Joseph Fourier Procede de determination du degre de sensibilite d'une souche de champignon vis-a-vis d'un antifongique
CN108289928A (zh) 2015-08-06 2018-07-17 哈佛大学校长及研究员协会 改进的微生物-结合分子和其用途
AU2016321328A1 (en) 2015-09-09 2018-04-26 Psomagen, Inc. Method and system for microbiome-derived diagnostics and therapeutics infectious disease and other health conditions associated with antibiotic usage
NZ743000A (en) * 2015-12-14 2022-08-26 Otakaro Pathways Ltd Screening and culture method
BR112018014146A2 (pt) * 2016-01-21 2018-12-11 Selux Diagnostics Inc métodos de teste rápido de suscetibilidade antimicrobiana
US9834808B2 (en) * 2016-01-21 2017-12-05 SeLux Diagnostics, Inc. Methods for rapid antibiotic susceptibility testing
WO2017127727A1 (en) 2016-01-21 2017-07-27 T2 Biosystems, Inc. Rapid antimicrobial susceptibility testing using high-sensitivity direct detection methods
US11454611B2 (en) 2016-04-14 2022-09-27 Micromass Uk Limited Spectrometric analysis of plants
EP4303312A3 (en) * 2016-04-22 2024-03-13 Selux Diagnostics, Inc. Performing antimicrobial susceptibility testing and related systems and methods
WO2017189632A1 (en) * 2016-04-25 2017-11-02 Aperture Bio, LLC Systems, devices and methods for sequential analysis of complex matrix samples for high confidence bacterial detection and drug susceptibility prediction using a flow cytometer
EP3455378A1 (en) 2016-05-10 2019-03-20 Viasphere, LLC Compositions and methods for identifying, quantifying, and/or characterizing an analyte
WO2018058078A1 (en) 2016-09-23 2018-03-29 California Institute Of Technology Digital quantification of dna replication and/or chromosome segregation based determination of antimicrobial susceptibility
EP3301454B1 (en) * 2016-10-03 2019-08-28 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
WO2018127853A1 (en) * 2017-01-09 2018-07-12 Pocared Diagnostics Ltd. Rapid antimicrobial susceptibility testing based on a unique spectral intensity ratio analysis via single fluorescence membrane dye staining and flow cytometry
CN110234749B (zh) 2017-02-02 2023-06-30 PhAST公司 分析和使用微生物的运动性运动学
US20200010870A1 (en) * 2017-03-13 2020-01-09 Ian Lewis Device, Method, And System For Identifying Organisms And Determining Their Sensitivity To Toxic Substances Using The Changes In The Concentrations Of Metabolites Present In Growth Medium
EP3596228B1 (en) * 2017-03-14 2022-09-28 Tubitak Method for rapid identification of microorganisms producing nuclease enzymes
EP3601588B1 (en) * 2017-03-22 2023-06-28 Astrego Diagnostics AB Phenotypic characterization of cells
WO2018203868A1 (en) 2017-04-30 2018-11-08 Genefluidics, Inc. Generation of data for use with antimicrobials
CN107121375A (zh) * 2017-05-26 2017-09-01 同济大学 一种饮用水中四环素抗性细菌的流式细胞仪检测方法
US10787695B2 (en) 2017-06-01 2020-09-29 General Electric Company Systems and methods for rapidly sensing microbial metabolism
US10995358B2 (en) * 2017-07-13 2021-05-04 Pocared Diagnostics Ltd. Rapid antibiotic susceptibility test using membrane fluorescence staining and spectral intensity ratio improved by flow cytometry dead to live population ratio
US20200263224A1 (en) * 2017-08-18 2020-08-20 Microbedx, Inc. Methods for Antimicrobial Susceptibility Testing
US11827944B2 (en) 2017-10-11 2023-11-28 California Institute Of Technology Antibiotic susceptibility of microorganisms and related compositions, methods and systems
EP3717657A1 (en) * 2017-11-30 2020-10-07 Ascilion AB A system for assessing microbial susceptibility to antibiotic agents
US11268960B2 (en) 2018-01-10 2022-03-08 SeLux Diagnostics, Inc. Assays for improving automated antimicrobial susceptibility testing accuracy
GB201801022D0 (en) * 2018-01-22 2018-03-07 Q Linea Ab Single dye concentration determination
CN108398419B (zh) * 2018-03-30 2020-06-30 华南师范大学 一种利用竞争型的纳米传感器超灵敏检测凝血酶的方法
CN112135789B (zh) 2018-05-08 2023-09-08 生物磁性解决方案有限责任公司 从柔性一次性袋中分离细胞的刚性腔室
EP3803395A4 (en) * 2018-05-26 2022-03-30 Centre for Cellular and Molecular Platforms (C-CAMP) MICROFLUID CARTRIDGE, KIT AND TEST
CN108866152A (zh) * 2018-06-06 2018-11-23 苏州艾可瑞动物检测技术服务有限公司 一种供兽医临床使用的高通量快速药敏检测试剂盒
KR102084688B1 (ko) * 2018-06-18 2020-03-04 울산과학기술원 다중 프로브 혼성화를 이용한 미생물 검출 방법
JP2021530986A (ja) * 2018-07-11 2021-11-18 セルックス・ダイアグノスティクス・インコーポレイテッド 抗菌剤感受性試験のためのアッセイ及び試薬
CN108982872B (zh) * 2018-07-25 2022-04-05 苏州丰泰医疗用品贸易有限公司 一种基于微球和荧光标记的快速检测抗原或抗体方法
US10738342B2 (en) 2018-08-30 2020-08-11 Urinary Technologies, Inc. System for microbial species detection, quantification and antibiotic susceptibility identification
SG11202102841WA (en) * 2018-09-28 2021-04-29 Octane Biotech Inc Magnetic separation
WO2020073018A2 (en) * 2018-10-04 2020-04-09 First Light Diagnostics, Inc. Test cartridges
US20230082300A1 (en) * 2018-10-25 2023-03-16 Renascent Diagnostics, Llc System and method for detecting a target bacteria
US20210278402A1 (en) * 2018-11-27 2021-09-09 Module Innovations Private Limited Method for testing of antibiotic susceptibility in microorganisms
CN109992241B (zh) * 2019-03-22 2020-12-08 广州大学 Dna分子螺旋除法器的构建方法及dna分子螺旋除法器
CN111826415A (zh) * 2019-04-18 2020-10-27 山东鑫科生物科技股份有限公司 一种抗菌药物对细菌的抑制检测方法
WO2020223511A1 (en) * 2019-04-30 2020-11-05 SeLux Diagnostics, Inc. Rapid methods for determining microorganism growth in samples of human origin
CN110294810B (zh) * 2019-06-26 2021-05-04 中国疾病预防控制中心传染病预防控制所 一种含有人IgG1Fc和甘露聚糖结合凝集素C端的重组蛋白
EP4004227A4 (en) * 2019-07-29 2023-08-30 Microbedx Inc. PROCEDURE FOR ANTIBIOTIC SUSCEPTIBILITY ANALYSIS OF BLOOD SAMPLES
EP4022079A1 (en) 2019-08-27 2022-07-06 Selux Diagnostics, Inc. Systems and methods for performing antimicrobial susceptibility testing
CN110669820A (zh) * 2019-11-11 2020-01-10 郑州安图生物工程股份有限公司 一种微生物药敏快速检测方法
TWI717104B (zh) * 2019-11-15 2021-01-21 台灣奈米碳素股份有限公司 產品標籤、提供生鮮食品即時資訊的系統及方法
WO2021133963A1 (en) 2019-12-23 2021-07-01 Miraki Innovation Think Tank Llc Sample preparation and microbial analysis
WO2021133943A1 (en) 2019-12-23 2021-07-01 Miraki Innovation Think Tank Llc Compositions, devices and methods for diagnosing and treating infectious disease
CN110921820B (zh) * 2019-12-25 2021-12-03 北京工业大学 利用苄索氯铵快速启动城市污水常温短程硝化的方法
WO2021243107A1 (en) * 2020-05-27 2021-12-02 The Regents Of The University Of California Methods and systems for rapid antimicrobial susceptibility tests
CA3196472A1 (en) 2020-06-12 2021-12-16 Miraki Innovation Think Tank Llc Lateral flow assay for rapid detection of pathogens in samples
WO2022026800A2 (en) 2020-07-31 2022-02-03 Miraki Innovation Think Tank Llc Mbl-coated substrates having anti-thrombogenic properties
CN111855753B (zh) * 2020-08-05 2023-04-07 中国水产科学研究院黄海水产研究所 一种水体中副溶血弧菌的现场检测试剂盒和检测方法
WO2022046558A1 (en) 2020-08-28 2022-03-03 Miraki Innovation Think Tank Llc Therapeutic compositions comprising microbe-targeting molecules and their use in methods of preventing and treating infectious disease
US20240019435A1 (en) 2020-09-25 2024-01-18 Miraki Innovation Think Tank Llc Compositions, devices and methods comprising microbe-targeting molecules for diagnosing and treating infectious disease
WO2022072674A1 (en) 2020-10-01 2022-04-07 Miraki Innovation Think Tank Llc Compositions, devices and methods for identifying, treating and preventing infectious disease using microbe-targeting molecules
WO2022081978A1 (en) * 2020-10-15 2022-04-21 SeLux Diagnostics, Inc. Rapid methods for determining microorganism growth in whole blood samples
WO2022093935A1 (en) 2020-10-27 2022-05-05 Miraki Innovation Think Tank Llc Compositions, systems and methods for pathogen monitoring using microbe-targeting molecules
WO2022125632A1 (en) 2020-12-08 2022-06-16 Miraki Innovation Think Tank Llc Chimeric antigen receptor-expressing cells targeting microbe-associated molecular patterns
IT202100003080A1 (it) * 2021-02-11 2022-08-11 Mectron S P A Un metodo per la cattura di batteri da sospensioni e relativo dispositivo
CN112986375A (zh) * 2021-02-23 2021-06-18 浙江医院 一种基于基质辅助激光解吸/电离飞行时间质谱的细菌药敏检测试剂盒及其应用
CN113189078B (zh) * 2021-03-04 2024-04-16 吉林大学 一种靶向药物的高通量筛选方法
CN113058029A (zh) * 2021-03-18 2021-07-02 西安交通大学 胶原凝集素-11在制备防治泌尿系统感染的药物中的应用
EP4320260A1 (en) * 2021-04-05 2024-02-14 Victor Tets Products for regulation of eukaryotic and microbial cells growth
CN113151393A (zh) * 2021-05-26 2021-07-23 宁德师范学院 离心过滤结合荧光染色判定液体菌种细菌污染情况的方法
EP4104928A1 (en) * 2021-06-14 2022-12-21 ShanX Medtech BV A microfluidic extracellular environment monitoring device
US20230030454A1 (en) * 2021-07-27 2023-02-02 Chang Gung University Method for identifying and treating streptococcus pyogenes infection
CN113684152A (zh) * 2021-08-30 2021-11-23 贵州安康医学检验中心有限公司 一种细菌保藏培养基及其制备方法
WO2023034954A1 (en) * 2021-09-03 2023-03-09 University Of Massachusetts Amplifiable metabolic labeling for detection of bacterial viability, growth and antibiotic susceptibility
EP4198141A1 (en) 2021-12-14 2023-06-21 C4Diagnostics Method for detecting and optionally quantifying microorganisms
WO2023228142A1 (en) * 2022-05-27 2023-11-30 Papyrus Diagnostics Private Limited A device and method for phenotypic detection of antimicrobial resistance to drugs using paper microfluidics
EP4310192A1 (en) 2022-07-21 2024-01-24 C4Diagnostics Method of determining the existence and/or degree of resistance of microorganisms to antimicrobial agents

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2868777B2 (ja) 1987-08-20 1999-03-10 チルドレンズ・ホスピタル・コーポレイション ヒトマンノース結合タンパク質
US5270199A (en) 1987-08-20 1993-12-14 The Children's Medical Center Corporation Human mannose-binding protein
US5137810A (en) 1989-04-26 1992-08-11 The University Of North Carolina Method of determining the gram sign of bacteria
WO1992002139A1 (en) 1990-07-30 1992-02-20 Agricultural Genetics Company Limited Insecticidal proteins
GB9020075D0 (en) 1990-09-14 1990-10-24 Filler Aaron G Contrast agents for magnetic resonance imaging of axonal transport
AUPN214095A0 (en) 1995-04-03 1995-04-27 Australian Water Technologies Pty Ltd Method for detecting microorganisms using flow cytometry
WO1997035619A1 (en) 1996-03-28 1997-10-02 Genitrix, L.L.C. Opsonin-enhanced cells, and methods of modulating an immune response to an antigen
US6117977A (en) 1996-04-24 2000-09-12 Genentech, Inc. Type C lectins
ZA973051B (en) 1996-04-24 1998-10-12 Genentech Inc Type c lectins
EP0822261B1 (en) 1996-07-29 2002-07-03 Academia Sinica Methods for rapid antimicrobial susceptibility testing
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
US5935804A (en) * 1997-03-21 1999-08-10 Laine; Roger A. Method for detecting eubacteria in biological samples with catalytically inactive murein binding enzymes
CN1259957B (zh) 1997-04-22 2012-08-22 茵维特罗根公司 产生由多个亚单位组成的aslv逆转录酶的方法
US7049099B2 (en) 1998-01-23 2006-05-23 Fuso Pharmaceutical Industries, Ltd. Recombinant human mannan-binding proteins and producing method of the same
JPH11206378A (ja) 1998-01-23 1999-08-03 Fuso Pharmaceutical Industries Ltd 組換えヒトマンナン結合タンパク質およびその製造方法
US6528624B1 (en) 1998-04-02 2003-03-04 Genentech, Inc. Polypeptide variants
AU5670299A (en) * 1998-10-19 2000-05-08 Cbd Technologies Ltd. Methods of concentrating microorganisms using affinity separation
EP1177448A2 (en) 1999-04-29 2002-02-06 Dade MicroScan Inc. A combined rapid anti-microbial susceptibility assay and microorganism identification system
ATE336260T1 (de) 1999-05-14 2006-09-15 Steffen Thiel Neue indikationen für mannan-binding lectin (mbl) zur behandlung von immungeschwächten patienten
US6503761B1 (en) 1999-10-19 2003-01-07 Kimberly-Clark Worldwide, Inc. Selective removal of contaminants from a surface using articles having magnets
WO2002032292A2 (en) 2000-10-18 2002-04-25 The Board Of Trustess Of The Leland Stanford Junior University Methods for development and use of diagnostic and therapeutic agents
GB0119274D0 (en) 2001-08-08 2001-10-03 Univ Durham Fusion proteins for insect control
US6900292B2 (en) 2001-08-17 2005-05-31 Lee-Hwei K. Sun Fc fusion proteins of human erythropoietin with increased biological activities
WO2003054164A2 (en) 2001-12-19 2003-07-03 Immunex Corporation C-type lectin polypeptide, polynucleotide and methods of making and use thereof
EP1335003A3 (en) 2002-02-06 2004-04-07 Toyo Boseki Kabushiki Kaisha Magnetic carrier capable of binding with protein and purification method of protein utilizing the magnetic carrier
US7291480B2 (en) * 2002-03-13 2007-11-06 Black Jennifer A Device and method for detecting antibiotic-inactivating enzymes
EP1499741A4 (en) 2002-03-13 2006-07-05 Univ Creighton DEVICE AND METHOD FOR DETECTION OF ANTIBIOTIC-INACTIVATED ENZYMES
DK1344533T3 (da) 2002-03-15 2007-01-08 Natimmune As Farmaceutiske præparater, der omfatter mannosebindende lectin
US7211396B2 (en) 2002-04-18 2007-05-01 Antibodyshop A/S Antibody pairs and kits for immunochemical determination of mannan-binding lectin
CN1646152A (zh) 2002-04-24 2005-07-27 昆士兰医学研究学院理事会 甘露糖结合凝集素及其应用
JP4892705B2 (ja) 2002-08-20 2012-03-07 オプサニテクス エルエルシー レクチン組成物および抗原に対する免疫反応を調節するための方法
US20060188963A1 (en) 2002-09-10 2006-08-24 Natlmmune A/S Collectin-complement activating protein chimeras
GB2393728A (en) 2002-10-04 2004-04-07 Nanomagnetics Ltd Magnetic nanoparticles
EP1417965A1 (en) 2002-11-07 2004-05-12 Vereniging Voor Christelijk Wetenschappelijk Onderwijs C-type lectin binding molecules, identification and uses thereof
CA2516403C (en) 2003-01-17 2014-08-12 Aethlon Medical, Inc. Method for removal of viruses from blood by lectin affinity hemodialysis
US20050014932A1 (en) 2003-05-15 2005-01-20 Iogenetics, Llc Targeted biocides
DE10325752A1 (de) 2003-06-06 2004-12-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Lektin-Konjugate
US7341841B2 (en) 2003-07-12 2008-03-11 Accelr8 Technology Corporation Rapid microbial detection and antimicrobial susceptibility testing
SE0401033D0 (sv) 2004-04-20 2004-04-20 Amersham Biosciences Ab Device and method for protein analysis
WO2007001332A2 (en) * 2004-08-04 2007-01-04 University Of Massachusetts Anti-pathogen immunoadhesins
WO2006046786A1 (en) 2004-10-28 2006-05-04 Dobeel Co., Ltd. Method for the mass production of multimeric mannose binding lectin
US20060141547A1 (en) 2004-11-16 2006-06-29 Das Hasi R Novel diagnostic marker, a diagnostic kit and a method for diagnosis of rheumatoid arthritis
US8084275B2 (en) 2005-02-08 2011-12-27 Fujifilm Corporation Magnetic composite body, production method thereof, method for removing substance with mannose on its surface, and method for concentrating substance with mannose on its surface
US9220831B2 (en) 2005-10-06 2015-12-29 Children's Medical Center Corporation Device and method for combined microfluidic-micromagnetic separation of material in continuous flow
US20070269818A1 (en) 2005-12-28 2007-11-22 Affymetrix, Inc. Carbohydrate arrays
US20090181041A1 (en) 2006-01-23 2009-07-16 Jan Holgersson Production of proteins carrying oligomannose or human-like glycans in yeast and methods of use thereof
US8088596B2 (en) 2006-10-10 2012-01-03 Oakland University Method of microorganism detection using carbohydrate and lectin recognition
GB0702183D0 (en) * 2007-02-05 2007-03-14 Iti Scotland Ltd Pathogen binding
US8292083B2 (en) 2007-04-19 2012-10-23 The Charles Stark Draper Laboratory, Inc. Method and apparatus for separating particles, cells, molecules and particulates
AU2008319384A1 (en) 2007-10-29 2009-05-07 Virginia Tech Intellectual Properties, Inc. Porcine DC-SIGN , ICAM-3 and LSECtin and uses thereof
US20110027267A1 (en) 2007-11-09 2011-02-03 Anaphore, Inc. Fusion Proteins of Mannose Binding Lectins for Treatment of Disease
WO2009079232A2 (en) * 2007-12-05 2009-06-25 Pathogen Control Associates (Dba Pathcon Laboratories) Method and apparatus for micro-organism capture
US20100266558A1 (en) 2007-12-18 2010-10-21 Dov Zipori Method and assay for glycosylation pattern detection related to cell state of stem cells
US20110183398A1 (en) 2007-12-31 2011-07-28 3M Innovative Properties Microorganism-capturing compositions and methods
US20100331240A1 (en) 2008-01-18 2010-12-30 The General Hospital Corporation Methods for prevention and treatment of infections with supraphysiological doses of mannan-binding lectin (mbl) and ficolin-mbl fusion proteins
US20110053250A1 (en) 2008-03-31 2011-03-03 Japan Tobacco Inc. Enrichment method of virus
WO2009123347A1 (ja) 2008-03-31 2009-10-08 日本たばこ産業株式会社 ウイルス定量法
US20100323429A1 (en) 2008-04-10 2010-12-23 Yu-Chen Hu Methods for purifying baculovirus
US8865876B2 (en) 2008-06-02 2014-10-21 California Institute Of Technology Engineered lectin oligomers with antiviral activity
US20110159000A1 (en) 2008-09-05 2011-06-30 The Regents Of The University Of California Antibodies with mannose binding lectin effector function for inhibiting pathologic inflammatory conditions
WO2010065765A2 (en) 2008-12-04 2010-06-10 Aethlon Medical, Inc. Affinity capture of circulating biomarkers
WO2010088261A1 (en) 2009-01-28 2010-08-05 Smartcells, Inc. Binding-site modified lectins and uses thereof
WO2010114727A1 (en) * 2009-04-03 2010-10-07 3M Innovative Properties Company Microorganism concentration process and device
DK2526119T3 (en) * 2010-01-19 2018-07-30 Harvard College Manipulated opsonin for pathogen detection and treatment
US20130157283A1 (en) * 2010-01-19 2013-06-20 President And Fellows Of Harvard College Rapid pathogen diagnostic device and method
CA2825008C (en) 2011-01-19 2020-10-13 President And Fellows Of Harvard College Slippery surfaces with high pressure stability, optical transparency, and self-healing characteristics
RU2013148071A (ru) * 2011-04-01 2015-05-10 Президент Энд Феллоуз Ов Харвард Колледж Аналогичное диализу терапевтическое (dlt) устройство
WO2013012924A2 (en) 2011-07-18 2013-01-24 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
WO2014014788A2 (en) 2012-07-18 2014-01-23 President And Fellows Of Harvard College Modification of surfaces for simulataneous repellency and targeted binding of desired moieties

Also Published As

Publication number Publication date
CN104284984A (zh) 2015-01-14
AU2013225823A1 (en) 2014-09-18
EP2820147A4 (en) 2015-10-14
CN104284984B (zh) 2017-10-13
EP2820147A1 (en) 2015-01-07
WO2013130875A1 (en) 2013-09-06
EP2820147B1 (en) 2018-08-08
US20150064703A1 (en) 2015-03-05
CA2865744A1 (en) 2013-09-06
US9632085B2 (en) 2017-04-25

Similar Documents

Publication Publication Date Title
HK1206066A1 (zh) 抗生素藥敏性的快速測試
EP2930491A4 (en) TEST DEVICE
EP2814984A4 (en) MIRNA ANALYSIS PROCEDURE
EP2887699A4 (en) TEST DEVICE FOR HEADPHONES
EP2715599A4 (en) APPLICATION SAFETY TEST
SG2013079553A (en) Rf testing system
GB2500074B (en) Debug architecture
EP2930707A4 (en) TEST DEVICE
EP2901346A4 (en) SAFETY TESTING OF AN APPLICATION
GB2499104B (en) Abrasion test methods and devices
EP2878953A4 (en) ANALYSIS DEVICE
PL2844762T3 (pl) Badanie wrażliwości na antybiotyki przy użyciu sond do pre-rybosomalnego RNA
EP2877926A4 (en) SAFETY TESTING OF AN APPLICATION
GB2507980B (en) Inspection arrangement
GB2507283B (en) Probe
GB2503882B (en) Debug architecture
EP2845006A4 (en) SAMPLE INTRODUCTION SYSTEM
EP2938865A4 (en) RETENTION OF COMPONENTS BY A PROBE
EP2832302A4 (en) PROBE
GB2501333B (en) Debug architecture
HK1215730A1 (zh) 樣品測試裝置
HK1207454A1 (zh) 場分析儀
EP2899655A4 (en) ANALYSIS DEVICE
PL2919622T3 (pl) Narzędzie pomiarowe
EP2826412A4 (en) PROBE