HK1199407A1 - 穩定化之蘿蔔硫素 - Google Patents

穩定化之蘿蔔硫素

Info

Publication number
HK1199407A1
HK1199407A1 HK14113030.9A HK14113030A HK1199407A1 HK 1199407 A1 HK1199407 A1 HK 1199407A1 HK 14113030 A HK14113030 A HK 14113030A HK 1199407 A1 HK1199407 A1 HK 1199407A1
Authority
HK
Hong Kong
Prior art keywords
stabilized sulforaphane
sulforaphane
stabilized
Prior art date
Application number
HK14113030.9A
Other languages
English (en)
Inventor
Albert Roger Frisbee
Peter Wyatt Newsome
Michel Pierre Baudet
Ido Dov Dagan
Original Assignee
Pharmagra Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39641899&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1199407(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmagra Labs Inc filed Critical Pharmagra Labs Inc
Publication of HK1199407A1 publication Critical patent/HK1199407A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/26—Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/18—Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms
    • C07C331/20—Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/26—Isothiocyanates having isothiocyanate groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/025—Purification; Separation; Stabilisation; Desodorisation of organo-phosphorus compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/16—Cyclodextrin; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
HK14113030.9A 2007-01-23 2014-12-29 穩定化之蘿蔔硫素 HK1199407A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88187507P 2007-01-23 2007-01-23

Publications (1)

Publication Number Publication Date
HK1199407A1 true HK1199407A1 (zh) 2015-07-03

Family

ID=39641899

Family Applications (2)

Application Number Title Priority Date Filing Date
HK14113030.9A HK1199407A1 (zh) 2007-01-23 2014-12-29 穩定化之蘿蔔硫素
HK19101165.6A HK1258801A1 (zh) 2007-01-23 2019-01-23 穩定的蘿蔔硫素

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK19101165.6A HK1258801A1 (zh) 2007-01-23 2019-01-23 穩定的蘿蔔硫素

Country Status (17)

Country Link
US (1) US7879822B2 (zh)
EP (4) EP3354267B1 (zh)
JP (4) JP2010516766A (zh)
AU (1) AU2008209543B2 (zh)
CA (1) CA2672971C (zh)
CY (1) CY1122136T1 (zh)
DK (2) DK3354267T3 (zh)
ES (2) ES2743043T3 (zh)
HK (2) HK1199407A1 (zh)
HR (1) HRP20191495T1 (zh)
HU (2) HUE046151T2 (zh)
LT (1) LT3354267T (zh)
PL (2) PL2796140T3 (zh)
PT (1) PT3354267T (zh)
SI (1) SI3354267T1 (zh)
TR (1) TR201808561T4 (zh)
WO (1) WO2008091608A1 (zh)

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BE1019434A3 (fr) * 2010-07-23 2012-07-03 Auriga Internat Stabilisation du sulforaphane.
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ES2425294B1 (es) * 2012-03-09 2014-09-02 Consejo Superior De Investigaciones Científicas (Csic) Compuestos derivados de sulforafano, método de obtención y su uso médico, alimenticio y cosmético
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DK2854861T3 (en) 2012-06-01 2018-01-02 Pharmagra Labs Inc PROCEDURE FOR SYNTHETIZING SULFORAPHAN
US10434081B2 (en) 2012-07-26 2019-10-08 The William M. Yarbrough Foundation Inhibitors of macrophage migration inhibitory factor
US9949943B2 (en) 2012-07-26 2018-04-24 The William M. Yarbrough Foundation Method for treating neurodegenerative diseases
US10434082B2 (en) 2012-07-26 2019-10-08 The William M. Yarbrough Foundation Isothiocyanate functional compounds augmented with secondary antineoplastic medicaments and associated methods for treating neoplasms
US10335387B2 (en) 2012-07-26 2019-07-02 The William M. Yarbrough Foundation Method for treating infectious diseases with isothiocyanate functional compounds
US9839621B2 (en) 2012-07-26 2017-12-12 The William M. Yarbrough Foundation Method for treating bladder cancer
US10080734B2 (en) 2012-07-26 2018-09-25 The William M. Yarbrough Foundation Method for treating autism and other neurodevelopmental disorders
US10441561B2 (en) 2012-07-26 2019-10-15 The William M. Yanbrough Foundation Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer
US8865772B2 (en) 2012-07-26 2014-10-21 The William M. Yarbrough Foundation Method for treating skin cancer
DE102014012367B3 (de) * 2014-08-25 2015-08-27 De Smaakmaker Holding B. V. Verfahren zum Bestimmen der Konzentration von Glucoraphanin und/oder von Sulforaphan in einer Pflanze
CN107468666B (zh) * 2017-08-18 2021-01-01 赣州华汉生物科技有限公司 一种可稳定保存的萝卜硫素胶囊及其制备方法
CN111902046A (zh) * 2018-02-02 2020-11-06 联邦科学技术研究组织 保护生物活性物和/或其前体
GB2574248B (en) * 2018-05-31 2021-03-03 Edwards Ltd Foreline for a vacuum pump
KR102457241B1 (ko) * 2020-02-26 2022-10-21 경일대학교산학협력단 페닐이소티오시아네이트를 처리하여 십자화과 식물로부터 설포라판을 생산하는 방법 및 보존하는 방법
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Also Published As

Publication number Publication date
EP2796140A2 (en) 2014-10-29
PT3354267T (pt) 2019-09-10
US20080176942A1 (en) 2008-07-24
EP2120969A1 (en) 2009-11-25
EP2796140B1 (en) 2018-05-02
SI3354267T1 (sl) 2019-11-29
AU2008209543B2 (en) 2014-03-13
DK3354267T3 (da) 2019-08-26
HUE039549T2 (hu) 2019-01-28
JP2014055140A (ja) 2014-03-27
EP3354267B1 (en) 2019-08-07
CY1122136T1 (el) 2020-11-25
EP2532352A1 (en) 2012-12-12
CA2672971A1 (en) 2008-07-31
CA2672971C (en) 2014-03-11
ES2743043T3 (es) 2020-02-18
HUE046151T2 (hu) 2020-02-28
WO2008091608A1 (en) 2008-07-31
DK2796140T3 (en) 2018-06-25
EP3354267A1 (en) 2018-08-01
HK1258801A1 (zh) 2019-11-22
ES2674052T3 (es) 2018-06-27
JP6677688B2 (ja) 2020-04-08
JP6566886B2 (ja) 2019-08-28
EP2796140A3 (en) 2014-12-24
US7879822B2 (en) 2011-02-01
TR201808561T4 (tr) 2018-07-23
HRP20191495T1 (hr) 2019-11-29
JP2016145218A (ja) 2016-08-12
JP2018027956A (ja) 2018-02-22
LT3354267T (lt) 2019-09-25
PL2796140T3 (pl) 2018-09-28
JP2010516766A (ja) 2010-05-20
EP2120969A4 (en) 2010-06-02
AU2008209543A1 (en) 2008-07-31
PL3354267T3 (pl) 2019-11-29

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