PL2796140T3 - Stabilizowany sulforafan - Google Patents

Stabilizowany sulforafan

Info

Publication number
PL2796140T3
PL2796140T3 PL14166888T PL14166888T PL2796140T3 PL 2796140 T3 PL2796140 T3 PL 2796140T3 PL 14166888 T PL14166888 T PL 14166888T PL 14166888 T PL14166888 T PL 14166888T PL 2796140 T3 PL2796140 T3 PL 2796140T3
Authority
PL
Poland
Prior art keywords
stabilized sulforaphane
sulforaphane
stabilized
Prior art date
Application number
PL14166888T
Other languages
English (en)
Inventor
Albert Roger Frisbee
Peter Wyatt Newsome
Michel Pierre Baudet
Ido Dov Dagan
Original Assignee
Pharmagra Labs, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39641899&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2796140(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmagra Labs, Inc. filed Critical Pharmagra Labs, Inc.
Publication of PL2796140T3 publication Critical patent/PL2796140T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/26Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16Isothiocyanates
    • C07C331/18Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms
    • C07C331/20Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16Isothiocyanates
    • C07C331/26Isothiocyanates having isothiocyanate groups bound to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/025Purification; Separation; Stabilisation; Desodorisation of organo-phosphorus compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/16Cyclodextrin; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/36Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
PL14166888T 2007-01-23 2008-01-23 Stabilizowany sulforafan PL2796140T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88187507P 2007-01-23 2007-01-23
EP08724719A EP2120969A4 (en) 2007-01-23 2008-01-23 STABILIZED SULFORAPHANE
EP14166888.9A EP2796140B1 (en) 2007-01-23 2008-01-23 Stabilized Sulforaphane

Publications (1)

Publication Number Publication Date
PL2796140T3 true PL2796140T3 (pl) 2018-09-28

Family

ID=39641899

Family Applications (2)

Application Number Title Priority Date Filing Date
PL14166888T PL2796140T3 (pl) 2007-01-23 2008-01-23 Stabilizowany sulforafan
PL18162130T PL3354267T3 (pl) 2007-01-23 2008-01-23 Stabilizowany sulforafan

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL18162130T PL3354267T3 (pl) 2007-01-23 2008-01-23 Stabilizowany sulforafan

Country Status (17)

Country Link
US (1) US7879822B2 (pl)
EP (4) EP2532352A1 (pl)
JP (4) JP2010516766A (pl)
AU (1) AU2008209543B2 (pl)
CA (1) CA2672971C (pl)
CY (1) CY1122136T1 (pl)
DK (2) DK3354267T3 (pl)
ES (2) ES2674052T3 (pl)
HK (2) HK1199407A1 (pl)
HR (1) HRP20191495T1 (pl)
HU (2) HUE039549T2 (pl)
LT (1) LT3354267T (pl)
PL (2) PL2796140T3 (pl)
PT (1) PT3354267T (pl)
SI (1) SI3354267T1 (pl)
TR (1) TR201808561T4 (pl)
WO (1) WO2008091608A1 (pl)

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PT3354267T (pt) * 2007-01-23 2019-09-10 Pharmagra Labs Inc Sulforafano estabilizado
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BE1019434A3 (fr) * 2010-07-23 2012-07-03 Auriga Internat Stabilisation du sulforaphane.
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US10273205B2 (en) 2011-01-03 2019-04-30 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating isothiocyanate functional surfactants and associated methods for treating biofilms
US11279674B2 (en) 2011-01-03 2022-03-22 The William M. Yarbrough Foundation Isothiocyanate functional surfactant and associated method of use
US9962361B2 (en) 2011-01-03 2018-05-08 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
US10308599B2 (en) 2011-01-03 2019-06-04 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
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ES2425294B1 (es) * 2012-03-09 2014-09-02 Consejo Superior De Investigaciones Científicas (Csic) Compuestos derivados de sulforafano, método de obtención y su uso médico, alimenticio y cosmético
CN102697764A (zh) * 2012-05-03 2012-10-03 苏州纳晶医药技术有限公司 一种含有异硫氰酸苯乙酯的肠溶固体制剂
CN104640573B (zh) * 2012-06-01 2017-08-01 法玛格拉实验室公司 萝卜硫烷的分离和纯化
DK2854861T3 (en) 2012-06-01 2018-01-02 Pharmagra Labs Inc PROCEDURE FOR SYNTHETIZING SULFORAPHAN
US8865772B2 (en) 2012-07-26 2014-10-21 The William M. Yarbrough Foundation Method for treating skin cancer
US10434082B2 (en) 2012-07-26 2019-10-08 The William M. Yarbrough Foundation Isothiocyanate functional compounds augmented with secondary antineoplastic medicaments and associated methods for treating neoplasms
US9949943B2 (en) 2012-07-26 2018-04-24 The William M. Yarbrough Foundation Method for treating neurodegenerative diseases
US9839621B2 (en) 2012-07-26 2017-12-12 The William M. Yarbrough Foundation Method for treating bladder cancer
US10335387B2 (en) 2012-07-26 2019-07-02 The William M. Yarbrough Foundation Method for treating infectious diseases with isothiocyanate functional compounds
US10441561B2 (en) 2012-07-26 2019-10-15 The William M. Yanbrough Foundation Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer
US10080734B2 (en) 2012-07-26 2018-09-25 The William M. Yarbrough Foundation Method for treating autism and other neurodevelopmental disorders
US10434081B2 (en) 2012-07-26 2019-10-08 The William M. Yarbrough Foundation Inhibitors of macrophage migration inhibitory factor
DE102014012367B3 (de) * 2014-08-25 2015-08-27 De Smaakmaker Holding B. V. Verfahren zum Bestimmen der Konzentration von Glucoraphanin und/oder von Sulforaphan in einer Pflanze
CN107468666B (zh) * 2017-08-18 2021-01-01 赣州华汉生物科技有限公司 一种可稳定保存的萝卜硫素胶囊及其制备方法
KR20200123795A (ko) * 2018-02-02 2020-10-30 커먼웰쓰 사이언티픽 앤드 인더스트리얼 리서치 오가니제이션 생체활성물 및/또는 이의 전구체의 보호
GB2574248B (en) * 2018-05-31 2021-03-03 Edwards Ltd Foreline for a vacuum pump
KR102457241B1 (ko) * 2020-02-26 2022-10-21 경일대학교산학협력단 페닐이소티오시아네이트를 처리하여 십자화과 식물로부터 설포라판을 생산하는 방법 및 보존하는 방법
GB202005238D0 (en) * 2020-04-08 2020-05-20 Evgen Pharma Plc Crystalline complexes
CA3175531A1 (en) 2020-04-23 2021-10-28 V. Theocharis KOFTIS Compositions for stabilizing an isothiocyanate
WO2023037934A1 (ja) * 2021-09-13 2023-03-16 富士フイルム株式会社 ビシクロアルカン化合物の包摂体の製造方法
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PT3354267T (pt) * 2007-01-23 2019-09-10 Pharmagra Labs Inc Sulforafano estabilizado

Also Published As

Publication number Publication date
EP2120969A4 (en) 2010-06-02
DK2796140T3 (en) 2018-06-25
PT3354267T (pt) 2019-09-10
HK1199407A1 (en) 2015-07-03
CY1122136T1 (el) 2020-11-25
CA2672971A1 (en) 2008-07-31
HK1258801A1 (zh) 2019-11-22
JP6677688B2 (ja) 2020-04-08
EP2796140A2 (en) 2014-10-29
JP2016145218A (ja) 2016-08-12
SI3354267T1 (sl) 2019-11-29
JP2010516766A (ja) 2010-05-20
JP6566886B2 (ja) 2019-08-28
CA2672971C (en) 2014-03-11
HRP20191495T1 (hr) 2019-11-29
WO2008091608A1 (en) 2008-07-31
AU2008209543B2 (en) 2014-03-13
JP2018027956A (ja) 2018-02-22
EP2532352A1 (en) 2012-12-12
US7879822B2 (en) 2011-02-01
AU2008209543A1 (en) 2008-07-31
HUE046151T2 (hu) 2020-02-28
TR201808561T4 (tr) 2018-07-23
DK3354267T3 (da) 2019-08-26
LT3354267T (lt) 2019-09-25
US20080176942A1 (en) 2008-07-24
HUE039549T2 (hu) 2019-01-28
EP3354267B1 (en) 2019-08-07
EP2796140B1 (en) 2018-05-02
ES2674052T3 (es) 2018-06-27
JP2014055140A (ja) 2014-03-27
PL3354267T3 (pl) 2019-11-29
EP2796140A3 (en) 2014-12-24
ES2743043T3 (es) 2020-02-18
EP3354267A1 (en) 2018-08-01
EP2120969A1 (en) 2009-11-25

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