HK1184686A1 - 用於治療乾眼症的地誇磷索和透明質酸或其鹽 - Google Patents
用於治療乾眼症的地誇磷索和透明質酸或其鹽Info
- Publication number
- HK1184686A1 HK1184686A1 HK13112123.0A HK13112123A HK1184686A1 HK 1184686 A1 HK1184686 A1 HK 1184686A1 HK 13112123 A HK13112123 A HK 13112123A HK 1184686 A1 HK1184686 A1 HK 1184686A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- diquafosol
- salts
- treatment
- hyaluronic acid
- dry eye
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Non-Alcoholic Beverages (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2010203198 | 2010-09-10 | ||
PCT/JP2011/070578 WO2012033189A1 (ja) | 2010-09-10 | 2011-09-09 | P2y2受容体作動薬およびヒアルロン酸またはその塩を組み合わせたことを特徴とするドライアイ治療剤、ドライアイの治療方法、ならびにその使用 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1184686A1 true HK1184686A1 (zh) | 2014-01-30 |
Family
ID=45810785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK13112123.0A HK1184686A1 (zh) | 2010-09-10 | 2013-10-28 | 用於治療乾眼症的地誇磷索和透明質酸或其鹽 |
Country Status (19)
Country | Link |
---|---|
US (1) | US9006208B2 (zh) |
EP (1) | EP2614838B1 (zh) |
JP (1) | JP5956735B2 (zh) |
KR (2) | KR101707269B1 (zh) |
CN (2) | CN103096929A (zh) |
AU (2) | AU2011299851A1 (zh) |
BR (1) | BR112013005438B1 (zh) |
CA (1) | CA2810481C (zh) |
DK (1) | DK2614838T3 (zh) |
EA (1) | EA026680B1 (zh) |
ES (1) | ES2569246T3 (zh) |
HK (1) | HK1184686A1 (zh) |
MX (1) | MX336944B (zh) |
MY (1) | MY170198A (zh) |
NZ (1) | NZ608202A (zh) |
PL (1) | PL2614838T3 (zh) |
SG (1) | SG188482A1 (zh) |
TW (1) | TWI519301B (zh) |
WO (1) | WO2012033189A1 (zh) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140221306A1 (en) * | 2010-12-28 | 2014-08-07 | Santen Pharmaceutical Co. Ltd | Ophthalmic solution comprising diquafosol, method for producing the same, and method for inhibiting formation of insoluble precipitate |
TR201820073T4 (tr) | 2012-03-26 | 2019-01-21 | Santen Pharmaceutical Co Ltd | Diquafosol içeren göz damlası. |
EP3613423B1 (en) | 2013-07-10 | 2022-10-26 | Matrix Biology Institute | Compositions of hyaluronan with high elasticity and uses thereof |
US9289494B2 (en) | 2013-11-20 | 2016-03-22 | RestorTears, LLC | Method of treating ocular disorders with compounds found in Harderian gland secretions |
JP6267003B2 (ja) * | 2014-02-27 | 2018-01-24 | 参天製薬株式会社 | ジクアホソルまたはその塩およびレバミピドまたはその塩を組み合わせたことを特徴とする涙液分泌促進剤 |
CN113143948A (zh) * | 2015-06-05 | 2021-07-23 | 参天制药株式会社 | 以向佩戴有软性隐形眼镜的干眼症患者的眼中滴入的方式使用为特征的干眼症治疗剂 |
JP2017052723A (ja) * | 2015-09-10 | 2017-03-16 | 株式会社Lttバイオファーマ | ドライアイ改善剤 |
PL3352766T3 (pl) | 2015-09-24 | 2021-08-02 | Matrix Biology Institute | Kompozycie z hialuronanem o dużej elastyczności i sposoby ich użycia |
EP3871682A1 (en) * | 2016-10-14 | 2021-09-01 | i.com Medical GmbH | Method for establishing, restoring, and preserving homeostasis of the ocular surface |
KR20190071674A (ko) | 2016-10-21 | 2019-06-24 | 라이온 가부시키가이샤 | 안과용 제제 및 안과용 약 |
CN107096016B (zh) * | 2017-06-26 | 2021-04-06 | 蒋广伟 | 一种缓解视力疲劳的滴液 |
RU2652581C1 (ru) * | 2017-07-03 | 2018-04-26 | федеральное государственное бюджетное образовательное учреждение высшего образования "Приволжский исследовательский медицинский университет" Министерства здравоохранения Российской Федерации | Способ лечения роговично-конъюнктивального ксероза |
KR102108552B1 (ko) * | 2018-05-15 | 2020-05-08 | 한국세라믹기술원 | 히알루론산 마이크로비드의 제조 방법 및 상기 히알루론산 마이크로비드의 용도 |
CN109260146A (zh) * | 2018-10-12 | 2019-01-25 | 广州大光制药有限公司 | 地夸磷索钠眼用即用型凝胶滴眼液及制备方法 |
CN113518646B (zh) | 2019-02-27 | 2023-12-12 | 参天制药株式会社 | 含有地夸磷索或其盐,乙烯基系高分子及纤维素系高分子的眼科用组合物 |
TW202122094A (zh) * | 2019-08-27 | 2021-06-16 | 日商參天製藥股份有限公司 | 含有迪夸弗索(diquafosol)或其鹽、及聚乙烯吡咯烷酮之水性眼科用組合物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01115902A (ja) | 1987-10-30 | 1989-05-09 | Showa Sangyo Co Ltd | ヒアルロン酸の製造法 |
US5900407A (en) * | 1997-02-06 | 1999-05-04 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with uridine triphosphates and related compounds |
ES2264197T3 (es) | 1997-02-06 | 2006-12-16 | Inspire Pharmaceuticals, Inc. | Dinucleotidos y sus usos. |
US7223744B2 (en) | 1997-02-10 | 2007-05-29 | Inspire Pharmaceuticals, Inc. | Pharmaceutical formulation comprising dinucleoside polyphosphates and salts thereof |
KR20010013797A (ko) | 1997-07-25 | 2001-02-26 | 인스파이어 파마슈티컬스 인코퍼레이티드 | 디(우리딘 5'-테트라포스페이트) 염 및 그의 제조방법과용도 |
JP2003160491A (ja) | 2001-09-11 | 2003-06-03 | Santen Pharmaceut Co Ltd | ジウリジンリン酸含有点眼液 |
-
2011
- 2011-09-09 SG SG2013017652A patent/SG188482A1/en unknown
- 2011-09-09 DK DK11823663.7T patent/DK2614838T3/en active
- 2011-09-09 NZ NZ60820211A patent/NZ608202A/en not_active IP Right Cessation
- 2011-09-09 KR KR1020137008451A patent/KR101707269B1/ko active IP Right Grant
- 2011-09-09 US US13/821,717 patent/US9006208B2/en not_active Expired - Fee Related
- 2011-09-09 TW TW100132506A patent/TWI519301B/zh not_active IP Right Cessation
- 2011-09-09 EP EP11823663.7A patent/EP2614838B1/en active Active
- 2011-09-09 KR KR1020177003213A patent/KR20170018462A/ko not_active Application Discontinuation
- 2011-09-09 BR BR112013005438-7A patent/BR112013005438B1/pt not_active IP Right Cessation
- 2011-09-09 CN CN2011800435775A patent/CN103096929A/zh active Pending
- 2011-09-09 EA EA201390364A patent/EA026680B1/ru not_active IP Right Cessation
- 2011-09-09 MX MX2013002677A patent/MX336944B/es active IP Right Grant
- 2011-09-09 ES ES11823663.7T patent/ES2569246T3/es active Active
- 2011-09-09 CA CA2810481A patent/CA2810481C/en not_active Expired - Fee Related
- 2011-09-09 PL PL11823663.7T patent/PL2614838T3/pl unknown
- 2011-09-09 MY MYPI2013000810A patent/MY170198A/en unknown
- 2011-09-09 WO PCT/JP2011/070578 patent/WO2012033189A1/ja active Application Filing
- 2011-09-09 JP JP2011197020A patent/JP5956735B2/ja active Active
- 2011-09-09 AU AU2011299851A patent/AU2011299851A1/en not_active Abandoned
- 2011-09-09 CN CN201611152170.7A patent/CN106729718A/zh active Pending
-
2013
- 2013-10-28 HK HK13112123.0A patent/HK1184686A1/zh not_active IP Right Cessation
-
2017
- 2017-02-07 AU AU2017200821A patent/AU2017200821B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EA201390364A1 (ru) | 2013-08-30 |
MX336944B (es) | 2016-02-03 |
TWI519301B (zh) | 2016-02-01 |
MY170198A (en) | 2019-07-09 |
DK2614838T3 (en) | 2016-05-02 |
JP2012077080A (ja) | 2012-04-19 |
AU2017200821A1 (en) | 2017-03-02 |
CN103096929A (zh) | 2013-05-08 |
KR101707269B1 (ko) | 2017-02-15 |
US20130172287A1 (en) | 2013-07-04 |
CA2810481C (en) | 2018-06-19 |
BR112013005438B1 (pt) | 2021-09-21 |
MX2013002677A (es) | 2013-06-13 |
EA026680B1 (ru) | 2017-05-31 |
TW201216971A (en) | 2012-05-01 |
AU2011299851A1 (en) | 2013-04-04 |
EP2614838A1 (en) | 2013-07-17 |
US9006208B2 (en) | 2015-04-14 |
SG188482A1 (en) | 2013-04-30 |
ES2569246T3 (es) | 2016-05-09 |
BR112013005438A2 (pt) | 2016-05-17 |
PL2614838T3 (pl) | 2016-10-31 |
EP2614838B1 (en) | 2016-04-20 |
JP5956735B2 (ja) | 2016-07-27 |
WO2012033189A1 (ja) | 2012-03-15 |
KR20130109130A (ko) | 2013-10-07 |
EP2614838A4 (en) | 2014-02-26 |
KR20170018462A (ko) | 2017-02-17 |
AU2017200821B2 (en) | 2018-08-30 |
CA2810481A1 (en) | 2012-03-15 |
NZ608202A (en) | 2014-08-29 |
CN106729718A (zh) | 2017-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20220909 |