HK1182387A1 - '- 用於抗病毒治療的 '-取代- -核苷前藥 - Google Patents
'- 用於抗病毒治療的 '-取代- -核苷前藥Info
- Publication number
- HK1182387A1 HK1182387A1 HK13109734.7A HK13109734A HK1182387A1 HK 1182387 A1 HK1182387 A1 HK 1182387A1 HK 13109734 A HK13109734 A HK 13109734A HK 1182387 A1 HK1182387 A1 HK 1182387A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- carba
- substituted
- antiviral treatment
- nucleoside prodrugs
- nucleoside
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000002777 nucleoside Substances 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34959710P | 2010-05-28 | 2010-05-28 | |
| US35335110P | 2010-06-10 | 2010-06-10 | |
| US36604110P | 2010-07-20 | 2010-07-20 | |
| PCT/US2011/038253 WO2011150288A1 (en) | 2010-05-28 | 2011-05-26 | 1'-substituted-carba-nucleoside prodrugs for antiviral treatment |
| US13/117,060 US8415308B2 (en) | 2010-05-28 | 2011-05-26 | 1′-substituted-carba-nucleoside prodrugs for antiviral treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1182387A1 true HK1182387A1 (zh) | 2013-11-29 |
Family
ID=45375840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK13109734.7A HK1182387A1 (zh) | 2010-05-28 | 2013-08-20 | '- 用於抗病毒治療的 '-取代- -核苷前藥 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8415308B2 (zh) |
| EP (1) | EP2576534B1 (zh) |
| JP (4) | JP5837577B2 (zh) |
| AR (1) | AR084389A1 (zh) |
| CY (1) | CY1115479T1 (zh) |
| DK (1) | DK2576534T3 (zh) |
| ES (1) | ES2465265T3 (zh) |
| HK (1) | HK1182387A1 (zh) |
| HR (1) | HRP20140370T1 (zh) |
| ME (1) | ME01882B (zh) |
| PL (1) | PL2576534T3 (zh) |
| PT (1) | PT2576534E (zh) |
| RS (1) | RS53244B (zh) |
| SI (1) | SI2576534T1 (zh) |
| SM (1) | SMT201400048B (zh) |
| TW (1) | TW201201815A (zh) |
| UY (1) | UY33414A (zh) |
| WO (1) | WO2011150288A1 (zh) |
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| EA020659B1 (ru) | 2008-04-23 | 2014-12-30 | Джилид Сайэнс, Инк. | 1'-замещённые карбануклеозидные аналоги для противовирусной терапии |
| CA2773773C (en) | 2009-09-21 | 2019-04-23 | Gilead Sciences, Inc. | Processes and intermediates for the preparation of 1'-substituted carba-nucleoside analogs |
| TW201201815A (en) * | 2010-05-28 | 2012-01-16 | Gilead Sciences Inc | 1'-substituted-carba-nucleoside prodrugs for antiviral treatment |
| KR102108864B1 (ko) | 2010-07-19 | 2020-05-12 | 길리애드 사이언시즈, 인코포레이티드 | 부분입체 이성질성으로 순수한 포스포라미데이트 전구약물의 제조 방법 |
| SI2595980T1 (sl) | 2010-07-22 | 2014-11-28 | Gilead Sciences, Inc. | Postopki in sestavki za zdravljenje paramyxoviridae virusnih infekcij |
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| JP2014514295A (ja) | 2011-03-31 | 2014-06-19 | アイディニックス ファーマシューティカルズ インコーポレイテッド | ウイルス感染の治療のための化合物および薬学的組成物 |
| TW201329096A (zh) | 2011-09-12 | 2013-07-16 | Idenix Pharmaceuticals Inc | 經取代羰氧基甲基磷酸醯胺化合物及用於治療病毒感染之藥學組成物 |
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| SG11201407674TA (en) | 2012-05-22 | 2014-12-30 | Idenix Pharmaceuticals Inc | D-amino acid compounds for liver disease |
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| EP2909222B1 (en) | 2012-10-22 | 2021-05-26 | Idenix Pharmaceuticals LLC | 2',4'-bridged nucleosides for hcv infection |
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| UA119050C2 (uk) | 2013-11-11 | 2019-04-25 | Ґілеад Саєнсиз, Інк. | ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ |
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| TWI678369B (zh) | 2014-07-28 | 2019-12-01 | 美商基利科學股份有限公司 | 用於治療呼吸道合胞病毒感染之噻吩並［３,２-ｄ］嘧啶、呋喃並［３,２-ｄ］嘧啶及吡咯並［３,２-ｄ］嘧啶化合物類 |
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| US7973013B2 (en) | 2009-09-21 | 2011-07-05 | Gilead Sciences, Inc. | 2'-fluoro substituted carba-nucleoside analogs for antiviral treatment |
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2011
- 2011-05-25 TW TW100118301A patent/TW201201815A/zh unknown
- 2011-05-26 PT PT117258384T patent/PT2576534E/pt unknown
- 2011-05-26 ES ES11725838.4T patent/ES2465265T3/es active Active
- 2011-05-26 SI SI201130154T patent/SI2576534T1/sl unknown
- 2011-05-26 WO PCT/US2011/038253 patent/WO2011150288A1/en active Application Filing
- 2011-05-26 EP EP11725838.4A patent/EP2576534B1/en active Active
- 2011-05-26 JP JP2013512264A patent/JP5837577B2/ja active Active
- 2011-05-26 ME MEP-2014-58A patent/ME01882B/me unknown
- 2011-05-26 US US13/117,060 patent/US8415308B2/en active Active
- 2011-05-26 PL PL11725838T patent/PL2576534T3/pl unknown
- 2011-05-26 DK DK11725838.4T patent/DK2576534T3/da active
- 2011-05-26 RS RS20140150A patent/RS53244B/en unknown
- 2011-05-27 AR ARP110101821A patent/AR084389A1/es not_active Application Discontinuation
- 2011-05-27 UY UY0001033414A patent/UY33414A/es active IP Right Grant
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2013
- 2013-08-20 HK HK13109734.7A patent/HK1182387A1/zh unknown
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2014
- 2014-04-02 CY CY20141100249T patent/CY1115479T1/el unknown
- 2014-04-11 SM SM201400048T patent/SMT201400048B/xx unknown
- 2014-04-22 HR HRP20140370AT patent/HRP20140370T1/hr unknown
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2015
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Also Published As
| Publication number | Publication date |
|---|---|
| JP6193332B2 (ja) | 2017-09-06 |
| WO2011150288A1 (en) | 2011-12-01 |
| SI2576534T1 (sl) | 2014-06-30 |
| HRP20140370T1 (hr) | 2014-05-23 |
| US8415308B2 (en) | 2013-04-09 |
| JP2018162268A (ja) | 2018-10-18 |
| DK2576534T3 (da) | 2014-04-22 |
| EP2576534A1 (en) | 2013-04-10 |
| JP5837577B2 (ja) | 2015-12-24 |
| AR084389A1 (es) | 2013-05-15 |
| PT2576534E (pt) | 2014-05-29 |
| EP2576534B1 (en) | 2014-03-19 |
| JP2013528184A (ja) | 2013-07-08 |
| US20120020921A1 (en) | 2012-01-26 |
| SMT201400048B (it) | 2014-05-07 |
| JP2016094404A (ja) | 2016-05-26 |
| UY33414A (es) | 2011-12-30 |
| ES2465265T3 (es) | 2014-06-05 |
| CY1115479T1 (el) | 2017-01-04 |
| PL2576534T3 (pl) | 2014-07-31 |
| TW201201815A (en) | 2012-01-16 |
| JP2018012706A (ja) | 2018-01-25 |
| ME01882B (me) | 2014-12-20 |
| RS53244B (en) | 2014-08-29 |
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