HK1176629A1 - Radiopaque, non- biodegradable, water - insoluble iodinated benzyl ethers of poly (vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof () - Google Patents

Radiopaque, non- biodegradable, water - insoluble iodinated benzyl ethers of poly (vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof ()

Info

Publication number
HK1176629A1
HK1176629A1 HK13103365.6A HK13103365A HK1176629A1 HK 1176629 A1 HK1176629 A1 HK 1176629A1 HK 13103365 A HK13103365 A HK 13103365A HK 1176629 A1 HK1176629 A1 HK 1176629A1
Authority
HK
Hong Kong
Prior art keywords
radiopaque
biodegradable
poly
preparation
water
Prior art date
Application number
HK13103365.6A
Other languages
English (en)
Chinese (zh)
Inventor
伊夫．謝瓦利埃
傑拉爾丁．阿古斯蒂
柯拉麗．紐芬愛格
埃裡克．德爾克
奧利弗．喬丹
格特．安德森
Original Assignee
克勞德伯納德裡昂第大學
國家科學研究中心
安蒂亞治療公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 克勞德伯納德裡昂第大學, 國家科學研究中心, 安蒂亞治療公司 filed Critical 克勞德伯納德裡昂第大學
Publication of HK1176629A1 publication Critical patent/HK1176629A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0442—Polymeric X-ray contrast-enhancing agent comprising a halogenated group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F116/00—Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical
    • C08F116/02—Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical by an alcohol radical
    • C08F116/04—Acyclic compounds
    • C08F116/06—Polyvinyl alcohol ; Vinyl alcohol
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F16/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical
    • C08F16/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical by an alcohol radical
    • C08F16/04—Acyclic compounds
    • C08F16/06—Polyvinyl alcohol ; Vinyl alcohol
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/18—Introducing halogen atoms or halogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D129/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Coating compositions based on hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Coating compositions based on derivatives of such polymers
    • C09D129/02—Homopolymers or copolymers of unsaturated alcohols
    • C09D129/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Surgical Instruments (AREA)
HK13103365.6A 2010-03-10 2013-03-18 Radiopaque, non- biodegradable, water - insoluble iodinated benzyl ethers of poly (vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof () HK1176629A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10156039A EP2365009A1 (en) 2010-03-10 2010-03-10 Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof
PCT/EP2011/053536 WO2011110589A1 (en) 2010-03-10 2011-03-09 Radiopaque, non- biodegradable, water - insoluble iodinated benzyl ethers of poly (vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof

Publications (1)

Publication Number Publication Date
HK1176629A1 true HK1176629A1 (en) 2013-08-02

Family

ID=42035808

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13103365.6A HK1176629A1 (en) 2010-03-10 2013-03-18 Radiopaque, non- biodegradable, water - insoluble iodinated benzyl ethers of poly (vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof ()

Country Status (13)

Country Link
US (2) US9115230B2 (pl)
EP (2) EP2365009A1 (pl)
JP (1) JP5696165B2 (pl)
KR (1) KR101753441B1 (pl)
CN (1) CN102781974B (pl)
AU (1) AU2011226138B2 (pl)
BR (1) BR112012019754B1 (pl)
CA (1) CA2786398C (pl)
DK (1) DK2545085T3 (pl)
ES (1) ES2603607T3 (pl)
HK (1) HK1176629A1 (pl)
PL (1) PL2545085T3 (pl)
WO (1) WO2011110589A1 (pl)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101443926B1 (ko) 2006-06-15 2014-10-02 마이크로벤션, 인코포레이티드 팽창성 중합체로 제조된 색전술용 장치
WO2009086208A2 (en) 2007-12-21 2009-07-09 Microvention, Inc. Hydrogel filaments for biomedical uses
US10716573B2 (en) 2008-05-01 2020-07-21 Aneuclose Janjua aneurysm net with a resilient neck-bridging portion for occluding a cerebral aneurysm
US10028747B2 (en) 2008-05-01 2018-07-24 Aneuclose Llc Coils with a series of proximally-and-distally-connected loops for occluding a cerebral aneurysm
KR101745748B1 (ko) 2009-10-26 2017-06-12 마이크로벤션, 인코포레이티드 팽창성 중합체로부터 제작된 색전술 장치
US9358140B1 (en) 2009-11-18 2016-06-07 Aneuclose Llc Stent with outer member to embolize an aneurysm
WO2012145431A2 (en) 2011-04-18 2012-10-26 Microvention, Inc. Embolic devices
WO2013158781A1 (en) 2012-04-18 2013-10-24 Microvention, Inc. Embolic devices
CA2876474C (en) 2012-06-14 2021-06-22 Microvention, Inc. Polymeric treatment compositions
WO2014062696A1 (en) 2012-10-15 2014-04-24 Microvention, Inc. Polymeric treatment compositions
CN117982687A (zh) * 2013-03-15 2024-05-07 生物兼容英国有限公司 可成像栓塞微球
GB2519738A (en) 2013-09-06 2015-05-06 Biocompatibles Uk Ltd Radiopaque polymers
GB2521997A (en) * 2013-09-06 2015-07-15 Biocompatibles Uk Ltd Radiopaque polymers
WO2015153996A1 (en) 2014-04-03 2015-10-08 Micro Vention, Inc. Embolic devices
EP3137124B1 (en) 2014-04-29 2019-01-09 Microvention, Inc. Polymers including active agents
US10092663B2 (en) 2014-04-29 2018-10-09 Terumo Corporation Polymers
WO2016201250A1 (en) 2015-06-11 2016-12-15 Microvention, Inc. Expansile device for implantation
CN108883189B (zh) * 2016-03-14 2022-06-21 生物相容性英国公司 包含颗粒的乳液
US10368874B2 (en) 2016-08-26 2019-08-06 Microvention, Inc. Embolic compositions
US10576182B2 (en) 2017-10-09 2020-03-03 Microvention, Inc. Radioactive liquid embolic
CN107899064A (zh) * 2017-10-27 2018-04-13 华威（深圳）医疗器械有限责任公司 一种可载药且兼具显影性的液体栓塞剂的制备方法及其用途
CN107754007A (zh) * 2017-12-06 2018-03-06 华威（深圳）医疗器械有限责任公司 一种核素的载体组合物及制备方法、液体栓塞剂及使用方法以及核素混合物
GB201810784D0 (en) * 2018-06-29 2018-08-15 Biocompatibles Uk Ltd Radiopaque polymers
GB201810788D0 (en) 2018-06-29 2018-08-15 Biocompatibles Uk Ltd Biodegradable polymer
WO2020003147A2 (en) 2018-06-29 2020-01-02 Biocompatibles Uk Limited Radiopaque polymers
CN109224119B (zh) * 2018-10-30 2021-02-23 北京大学深圳医院 一种π共轭纳米自组装颗粒瘤内注射栓塞肿瘤血管抗癌剂
CN113348001B (zh) * 2018-11-13 2022-10-21 上海盛迪医药有限公司 一种聚合物及其组合物
WO2020202210A1 (en) * 2019-04-03 2020-10-08 Sree Chitra Tirunal Institute For Medical Sciences And Technology A radiopaque polymeric liquid embolic system
GB201910286D0 (en) * 2019-07-18 2019-09-04 Biocompatibles Uk Ltd Radiopaque polymers
CN110372484B (zh) * 2019-07-23 2020-05-22 赵修文 一种不透射线的聚乙烯醇微球
WO2021102241A1 (en) * 2019-11-20 2021-05-27 The Regents Of The University Of California Liquid embolic material composition
US20210290816A1 (en) * 2020-03-17 2021-09-23 Microvention, Inc. Liquid embolics
CN113651906B (zh) * 2020-05-12 2024-02-20 上海盛迪医药有限公司 一种共聚物及其组合物
US20220242817A1 (en) 2021-01-12 2022-08-04 Boston Scientific Scimed Inc. Iodinated compounds having radiocontrast properties
US11801058B2 (en) * 2021-03-04 2023-10-31 Accumedical Beijing Ltd. Liquid embolic compositions
CN117915963A (zh) 2021-07-12 2024-04-19 波士顿科学国际有限公司 不透射线组合物
CN113995884A (zh) * 2021-09-10 2022-02-01 苏州浩微生物医疗科技有限公司 一种液体栓塞剂及其制备方法
CN116115818B (zh) * 2021-11-12 2024-06-28 重庆百迈腾世医药科技有限公司 活性金属微球、基于活性金属微球的复合栓塞剂及其应用
CN114146190B (zh) * 2021-12-30 2024-01-26 科睿驰（深圳）医疗科技发展有限公司 一种高悬浮性显影微球及其制备方法
CN114262279B (zh) * 2021-12-30 2022-12-16 上海汇禾医疗科技有限公司 一种x射线可显影分子、栓塞微球及其制备方法
CN114805644B (zh) * 2022-06-24 2022-09-16 苏州美创医疗科技有限公司 一种不透射聚合物及其制备方法和应用
CN115490639B (zh) * 2022-09-19 2023-05-16 科睿驰（深圳）医疗科技发展有限公司 X射线显影化合物及其制备方法、x射线显影栓塞材料及其制备方法
CN115590984B (zh) * 2022-09-22 2023-07-14 科睿驰（深圳）医疗科技发展有限公司 X射线显影化合物及其制备方法、x射线显影微球及其制备方法
CN117586440B (zh) * 2024-01-17 2024-04-09 苏州美创医疗科技有限公司 一种碘化多羟基聚合物、制备方法及其制备的液体栓塞剂
CN117582535B (zh) * 2024-01-18 2024-04-26 上海汇禾医疗科技股份有限公司 一种液体栓塞剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4406878A (en) * 1978-08-02 1983-09-27 Eastman Kodak Company Iodinated contrast agent for radiography
US5667767A (en) 1995-07-27 1997-09-16 Micro Therapeutics, Inc. Compositions for use in embolizing blood vessels
US5580568A (en) 1995-07-27 1996-12-03 Micro Therapeutics, Inc. Cellulose diacetate compositions for use in embolizing blood vessels
US5695480A (en) 1996-07-29 1997-12-09 Micro Therapeutics, Inc. Embolizing compositions
JP2001524096A (ja) * 1997-04-24 2001-11-27 ニコムド イメージング エイエス コントラスト剤を含む不溶性微粒子または小胞を使用する塞栓治療
WO1999012577A1 (en) * 1997-09-05 1999-03-18 Nycomed Imaging As Polymer particles made of polyvinyl alcohol and comprising a contrast agent for chemoembolization
ATE273341T1 (de) * 1997-11-07 2004-08-15 Univ Rutgers Strikt alternierende poly(alkylenoxid)copolymere
US6365169B1 (en) * 1999-09-30 2002-04-02 Solomon Rosenblatt Polymeric broad spectrum antimicrobial coatings
US20060292077A1 (en) * 2005-03-18 2006-12-28 Zhao Jonathon Z Dendritic and star-shaped contrast agents for medical devices and bioabsorbable radiopaque bulk material and method for producing same
WO2006125452A1 (en) 2005-05-23 2006-11-30 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
JP4344779B2 (ja) * 2007-03-20 2009-10-14 国立大学法人九州大学 鉄錯体及び該鉄錯体を触媒とする重合体の製造方法
CN101513542B (zh) * 2009-03-27 2012-08-15 山东大正医疗器械股份有限公司 一种含碘可长期自身显影液体栓塞剂的制备方法

Also Published As

Publication number Publication date
JP2013521087A (ja) 2013-06-10
CN102781974A (zh) 2012-11-14
CA2786398A1 (en) 2011-09-15
DK2545085T3 (en) 2016-12-05
WO2011110589A1 (en) 2011-09-15
EP2365009A1 (en) 2011-09-14
US20130108574A1 (en) 2013-05-02
ES2603607T3 (es) 2017-02-28
US9434800B2 (en) 2016-09-06
AU2011226138B2 (en) 2015-01-22
CA2786398C (en) 2017-06-13
KR101753441B1 (ko) 2017-07-03
EP2545085A1 (en) 2013-01-16
AU2011226138A1 (en) 2012-07-26
US9115230B2 (en) 2015-08-25
BR112012019754A2 (pt) 2016-05-10
JP5696165B2 (ja) 2015-04-08
PL2545085T3 (pl) 2017-08-31
US20150335779A1 (en) 2015-11-26
CN102781974B (zh) 2014-10-15
EP2545085B1 (en) 2016-10-19
KR20130051916A (ko) 2013-05-21
BR112012019754B1 (pt) 2020-10-20

Similar Documents

Publication Publication Date Title
HK1176629A1 (en) Radiopaque, non- biodegradable, water - insoluble iodinated benzyl ethers of poly (vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof ()
HK1247133A1 (zh) 低醚組合物及輸送裝置
IL224984A (en) Coding agent cd33, a method of preparation and a pharmaceutical composition containing it
BR112012000652A2 (pt) composições contendo partículas de liberação de agente de benefício
IL225637A0 (en) The compositions, tablets containing such compositions, their use and a process for their preparation
EP2231133A4 (en) METHOD AND COMPOSITION FOR THE ADMINISTRATION OF RESVERATROL AND PTEROSTILS
IL212081A0 (en) Pharmaceutical compositions with attenuated release of phenolic opioids
EP2512460A4 (en) METHOD AND COMPOSITIONS FOR STABLE LIQUID ACTIVE FORMULATIONS
EP2299828A4 (en) COMPOSITIONS FOR LOW USE AGRICULTURE AND METHODS OF USE
HK1144787A1 (en) Anti-fmd vaccine composition and preparation and use thereof
EP2429591A4 (en) FLUORESCENT PHOSPHOLIPIDETHEROL COMPOUNDS AND COMPOSITIONS AND METHOD FOR THEIR USE
EP2447253A4 (en) DIHYDROPYRIMIDIN COMPOUNDS AND MANUFACTURING METHOD, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
IL215684A0 (en) Trehalulose-containing composition, its preparation and use
IL213452A0 (en) Phenylpyrimidone compounds, pharmaceutical compositions, preparation methods and uses thereof
HK1179962A1 (en) Tricyclic indazole compound, method of preparation and pharmaceutical composition containing it
EP2504331A4 (en) COMPOUND, SOME NEW FORMS THEREOF, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF PREPARATION AND USE
HRP20180793T1 (hr) Farmaceutski pripravak i oblik doziranja koji sadrži dronedaron, te postupak njegove priprave
ZA201201442B (en) Benzyl aralkyl ether compounds, methods for preparing same, intermediate compounds, use of said compounds, method for treatment and/or prevention, pharmaceutical composition and medicament containing same
EP2604289A4 (en) RADIALFORM OF A POLYMER COMPOUND WITH JOD, METHOD OF MANUFACTURING THEREOF, AND CT CONTRASTING COMPOSITION THEREWITH
IL210279A0 (en) Extended release compositions for high solubility, high permeability acdtive pharmaceutical ingredients
ZA201203531B (en) Certain crystalline hydrates, pharmaceutical compositions thereof and methods for preparation and use thereof
GB201210536D0 (en) Composition, use and method of preparation thereof
HK1169986A1 (en) New bicyclic dioxanes, their preparation and their use as fragrant compounds
EP2452681A4 (en) SALTS OF 13A- (S-) DESOXYTYLPHORININE, METHOD FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF
GB0801159D0 (en) New glass ionomer cement formulations with enhanced physical properties, for application in dentistry and orthopaedics as bone cement

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230313