HK1160139A1 - Biocidal boronophthalide compounds 2-[c] - Google Patents

Biocidal boronophthalide compounds 2-[c]

Info

Publication number
HK1160139A1
HK1160139A1 HK12100416.2A HK12100416A HK1160139A1 HK 1160139 A1 HK1160139 A1 HK 1160139A1 HK 12100416 A HK12100416 A HK 12100416A HK 1160139 A1 HK1160139 A1 HK 1160139A1
Authority
HK
Hong Kong
Prior art keywords
boronophthalide
biocidal
compounds
boronophthalide compounds
biocidal boronophthalide
Prior art date
Application number
HK12100416.2A
Other languages
English (en)
Chinese (zh)
Inventor
Stephen Baker
Tsutomu Akama
Carolyn Bellinger-Kawahara
Vincent Hernandez
Hold Karin G
James Leyden
Kirk Maples
Jacob Plattner
Virginia Sanders
Yong-Kang Zhang
Original Assignee
Anacor Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36917059&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1160139(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Anacor Pharmaceuticals Inc filed Critical Anacor Pharmaceuticals Inc
Publication of HK1160139A1 publication Critical patent/HK1160139A1/xx

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61P31/14—Antivirals for RNA viruses
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04—Amoebicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/027—Organoboranes and organoborohydrides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
HK12100416.2A 2005-02-16 2008-03-11 Biocidal boronophthalide compounds 2-[c] HK1160139A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65406005P 2005-02-16 2005-02-16

Publications (1)

Publication Number Publication Date
HK1160139A1 true HK1160139A1 (en) 2012-08-10

Family

ID=36917059

Family Applications (3)

Application Number Title Priority Date Filing Date
HK08102801.7A HK1109735A1 (en) 2005-02-16 2008-03-11 Halogen-substituted boronophthalides for the treatment of infections
HK12100416.2A HK1160139A1 (en) 2005-02-16 2008-03-11 Biocidal boronophthalide compounds 2-[c]
HK16110032.1A HK1221956A1 (zh) 2005-02-16 2016-08-23 用於治療感染的鹵代類苯酞化硼

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK08102801.7A HK1109735A1 (en) 2005-02-16 2008-03-11 Halogen-substituted boronophthalides for the treatment of infections

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK16110032.1A HK1221956A1 (zh) 2005-02-16 2016-08-23 用於治療感染的鹵代類苯酞化硼

Country Status (26)

Country Link
US (11) US7582621B2 (fr)
EP (4) EP2343304B1 (fr)
JP (6) JP5038912B2 (fr)
KR (4) KR101337045B1 (fr)
CN (2) CN101160124A (fr)
AU (3) AU2006214247C1 (fr)
BR (1) BRPI0608431B8 (fr)
CA (1) CA2597982C (fr)
CY (3) CY1120695T1 (fr)
DK (3) DK2343304T3 (fr)
ES (4) ES2872962T3 (fr)
FR (1) FR20C1024I2 (fr)
HK (3) HK1109735A1 (fr)
HU (4) HUE054365T2 (fr)
IL (2) IL185080A (fr)
LT (1) LTC2343304I2 (fr)
LU (1) LUC00157I2 (fr)
MX (1) MX369262B (fr)
NL (1) NL301049I2 (fr)
NZ (3) NZ598441A (fr)
PL (4) PL3424932T3 (fr)
PT (4) PT2987796T (fr)
RU (3) RU2414906C2 (fr)
SI (3) SI2343304T1 (fr)
WO (1) WO2006089067A2 (fr)
ZA (4) ZA200707408B (fr)

Families Citing this family (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820186B2 (en) 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
HUE054365T2 (hu) 2005-02-16 2021-09-28 Anacor Pharmaceuticals Inc Bór-ftalidok terápiás alkalmazásra
US7767657B2 (en) 2005-02-16 2010-08-03 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US7793666B2 (en) * 2005-07-28 2010-09-14 Innovation Biomedical Devices, Inc. Apparatus and method for treatment of infected nail
RU2642628C2 (ru) * 2006-02-16 2018-01-25 Анакор Фармасьютикалз, Инк. Бор-содержащие малые молекулы в качестве противовоспалительных средств
JP2009536660A (ja) * 2006-05-02 2009-10-15 アナコール ファーマシューティカルズ，インコーポレイテッド 加水分解耐性ホウ素含有治療剤及びその使用方法
EP1900378A1 (fr) * 2006-08-31 2008-03-19 Novartis AG Compositions pharmaceutiques pour le traitment d'infections fongiques
JO3598B1 (ar) 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
FR2910320B1 (fr) * 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
FR2910321B1 (fr) 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc Gel creme comprenant au moins un retinoide et du peroxyde de benzole
JO3396B1 (ar) 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون
US20090175810A1 (en) 2008-01-03 2009-07-09 Gareth Winckle Compositions and methods for treating diseases of the nail
JP2015178508A (ja) * 2008-01-09 2015-10-08 アナコール ファーマシューティカルズ，インコーポレイテッド 抗炎症剤としてのホウ素含有小分子
EP2187893A4 (fr) * 2008-03-06 2012-02-22 Anacor Pharmaceuticals Inc Petites molécules contenant du bore utilisées en tant qu'agents anti-inflammatoires
KR20150065941A (ko) 2008-03-06 2015-06-15 아나코르 파마슈티칼스 인코포레이티드 소염제로써 붕소가 함유된 소분자
TW201000107A (en) 2008-04-09 2010-01-01 Infinity Pharmaceuticals Inc Inhibitors of fatty acid amide hydrolase
WO2009140309A2 (fr) * 2008-05-12 2009-11-19 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore
US20100021530A1 (en) * 2008-07-25 2010-01-28 Innovation Biomedical Devices, Inc. Enhanced trans-keratin drug delivery
WO2010028005A1 (fr) 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore
EP2348863A4 (fr) 2008-09-04 2012-03-07 Anacor Pharmaceuticals Inc Petites molécules contenant du bore
US9493489B2 (en) 2008-10-15 2016-11-15 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agents
WO2010080558A1 (fr) * 2008-12-17 2010-07-15 Anacor Pharmaceuticals, Inc. Formes polymorphiques du (s)-3-aminométhyl-7-(3-hydroxy-propoxy)-3h-benzo[c][1,2]oxaborol-1-ol
WO2010118159A1 (fr) 2009-04-07 2010-10-14 Infinity Pharmaceuticals, Inc. Inhibiteurs d'hydrolase d'amide d'acide gras
AU2010234445A1 (en) 2009-04-07 2011-11-03 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
JP2013500974A (ja) 2009-07-28 2013-01-10 アナコール ファーマシューティカルズ，インコーポレイテッド 三置換ホウ素含有分子
WO2011019612A1 (fr) 2009-08-14 2011-02-17 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore en tant qu'agents antiprotozoaires
WO2011019616A1 (fr) 2009-08-14 2011-02-17 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore à titre d'agents anti-protozoaires
AP4039A (en) 2009-08-14 2017-02-28 Daitao Chen Boron-containing small molecules as antiprotozoal agents
MX2012002031A (es) 2009-08-19 2012-07-04 Anacor Pharmaceuticals Inc Moleculas pequeñas que contienen boro como agentes antiprotozoarios.
WO2011037731A1 (fr) 2009-09-25 2011-03-31 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore
US8979820B2 (en) 2009-10-09 2015-03-17 Cynthia S. Bailey Method and apparatus for improving the appearance of nails affected by onychomycosis through the topical application of an aqueous solution containing boric acid and camphor or other terpenes
WO2011049971A1 (fr) 2009-10-20 2011-04-28 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore comme agents antiprotozoaires
WO2011060199A1 (fr) 2009-11-11 2011-05-19 Anacor Pharmaceuticals, Inc. Petites molecules contenant du bore
WO2011063293A1 (fr) 2009-11-20 2011-05-26 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore en tant qu'agents antihelminthes
WO2011094450A1 (fr) 2010-01-27 2011-08-04 Anacor Pharmaceuticals, Inc Petites molecules contenant du bore
RU2569061C2 (ru) 2010-02-03 2015-11-20 Инфинити Фармасьютикалз, Инк. Ингибиторы амид-гидролазы жирных кислот
WO2011116348A1 (fr) 2010-03-19 2011-09-22 Anacor Pharmaceuticals, Inc. Petites molécules borées en tant qu'agent anti-protozoaire
US8039494B1 (en) 2010-07-08 2011-10-18 Dow Pharmaceutical Sciences, Inc. Compositions and methods for treating diseases of the nail
KR102087313B1 (ko) * 2010-08-10 2020-03-11 렘펙스 파머수티클스 인코퍼레이티드 고리형 보론산 에스터 유도체의 제조방법
HRP20211762T1 (hr) 2010-09-07 2022-02-18 Anacor Pharmaceuticals, Inc. Derivati benzoksaborola za liječenje bakterijskih infekcija
US9012491B2 (en) 2011-08-31 2015-04-21 Rempex Pharmaceuticals, Inc. Heterocyclic boronic acid ester derivatives and therapeutic uses thereof
US9162999B2 (en) 2011-09-28 2015-10-20 Wisconsin Alumni Research Foundation Catalytic conversion of cellulose to fuels and chemicals using boronic acids
BR112014008186A2 (pt) * 2011-10-07 2017-04-11 Syngenta Participations Ag método para proteção de plantas úteis ou material de propagação de plantas
AR088668A1 (es) * 2011-11-21 2014-06-25 Lilly Co Eli Moleculas pequeñas que contienen boro
AR088669A1 (es) 2011-11-21 2014-06-25 Lilly Co Eli Derivados de dihidrodibenzo[c][1,2]oxaborol y dihidroisoxazol utiles para el control de ectoparasitos
US9156858B2 (en) 2012-05-23 2015-10-13 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US10561675B2 (en) 2012-06-06 2020-02-18 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
WO2014007831A1 (fr) 2012-07-06 2014-01-09 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore
US9241947B2 (en) 2013-01-04 2016-01-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
MX2015008627A (es) 2013-01-04 2015-09-23 Rempex Pharmaceuticals Inc Derivados de acido boronico y usos terapeuticos de los mismos.
EA201591003A1 (ru) 2013-01-04 2015-12-30 Ремпекс Фармасьютикалз, Инк. Производные бороновой кислоты и их терапевтическое применение
US9101638B2 (en) 2013-01-04 2015-08-11 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US8669207B1 (en) * 2013-01-30 2014-03-11 Dow Agrosciences, Llc. Compounds and compositions
US11039617B2 (en) 2013-01-30 2021-06-22 Agrofresh Inc. Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
US10070649B2 (en) 2013-01-30 2018-09-11 Agrofresh Inc. Volatile applications against pathogens
JP5927686B1 (ja) 2013-01-30 2016-06-01 アグロフレッシュ インコーポレイテッド 食肉、植物または植物の一部分に対する揮発性抗菌剤としてのベンゾオキサボロールの使用
US9585396B2 (en) 2013-01-30 2017-03-07 Agrofresh Inc. Volatile applications against pathogens
US8778365B1 (en) 2013-01-31 2014-07-15 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US9452173B2 (en) 2013-01-31 2016-09-27 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US9446131B2 (en) 2013-01-31 2016-09-20 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US9433680B2 (en) 2013-01-31 2016-09-06 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
AP2015008638A0 (en) 2013-02-01 2015-08-31 Anacor Pharmaceuticals Inc Boron-containing small molecules as antiprotozoal agents
AR094961A1 (es) 2013-03-15 2015-09-09 Lilly Co Eli 1-hidroxi-benzooxaboroles como agentes antiparasitarios
AU2014202928B1 (en) * 2013-06-05 2014-09-11 Agrofresh Inc. Compounds and compositions
CN104224810B (zh) * 2013-06-20 2017-04-19 中国科学院上海生命科学研究院 一种化合物及其衍生物治疗肺炎球菌感染性疾病的用途
KR101636431B1 (ko) 2013-07-30 2016-07-05 동아에스티 주식회사 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
EP4029870A1 (fr) 2013-08-09 2022-07-20 GlaxoSmithKline Intellectual Property (No.2) Limited Composés de benzoxaborole tricyclique et leurs utilisations
CA2924748C (fr) 2013-10-03 2019-09-03 Dow Pharmaceutical Sciences, Inc. Formules d'efinaconazole stabilise
EP3071295A4 (fr) 2013-11-22 2017-05-31 Dow Pharmaceutical Sciences, Inc. Procédés, compositions et dispositifs anti-infectieux
CA2938799A1 (fr) 2014-02-17 2015-08-20 Syngenta Paticipations Ag Benzoxaboroles a effet microbiocide
WO2015134500A1 (fr) 2014-03-03 2015-09-11 Cook Medical Technologies Llc Dilatateur mécanique
JP2015212249A (ja) * 2014-05-05 2015-11-26 アナコール ファーマシューティカルズ，インコーポレイテッド 化合物および爪光沢剤
EP3139930A4 (fr) 2014-05-05 2018-01-17 Rempex Pharmaceuticals, Inc. Sels et polymorphes de dérivés cycliques d'ester d'acide boronique, et leurs utilisations thérapeutiques
US10385074B2 (en) 2014-05-05 2019-08-20 Rempex Pharmaceuticals, Inc. Synthesis of boronate salts and uses thereof
AU2015259744B2 (en) * 2014-05-12 2020-04-30 Agrofresh Inc. Volatile applications against pathogens
JP6672176B2 (ja) 2014-05-19 2020-03-25 レンペックス・ファーマシューティカルズ・インコーポレイテッド ボロン酸誘導体およびその治療的使用
WO2016001834A1 (fr) 2014-07-01 2016-01-07 Daiichi Sankyo Company, Limited Benzoxaboroles tricycliques en tant qu'agents antibactériens
AU2015284307A1 (en) 2014-07-01 2017-02-02 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
HUE056178T2 (hu) 2014-10-21 2022-01-28 Hexima Ltd Módszer gombafertõzések kezelésére
US10662205B2 (en) 2014-11-18 2020-05-26 Qpex Biopharma, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
MA41494B1 (fr) 2015-02-12 2020-10-28 Glaxosmithkline Ip No 2 Ltd Composés benzoxaborole substitués en position 4 et utilisations associées
US20180051041A1 (en) 2015-03-17 2018-02-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
KR101580077B1 (ko) * 2015-03-28 2015-12-24 한국콜마주식회사 시크로피록스 함유 네일락카 조성물
BR112017021380A2 (pt) 2015-04-09 2018-07-03 Anacor Pharmaceuticals Inc composto, combinação, formulação farmacêutica, método de extermínio e/ou prevenção do crescimento de um protozoário, e, uso de composto
EP3280262B1 (fr) * 2015-04-09 2022-07-06 The Penn State Research Foundation Composition antifongicide contenant du benzoxaborole
WO2016201440A1 (fr) * 2015-06-12 2016-12-15 The Regents Of The University Of California Spiro-indolinones et leurs utilisations thérapeutiques
US10160867B2 (en) * 2015-08-06 2018-12-25 The Penn State Research Foundation Benzoxaborole-containing coating resistant to cellulose-supportable fungus
CN106467557B (zh) * 2015-08-18 2019-05-03 北京海美桐医药科技有限公司 他瓦硼罗的一种制备方法
SI3383363T1 (sl) * 2015-11-30 2021-03-31 Anacor Pharmaceuticals, Inc. Topične farmacevtske formulacije za zdravljenje vnetnih bolezenskih stanj
US10611781B2 (en) 2016-03-02 2020-04-07 Bill And Melinda Gates Foundation Boron-containing small molecules
US10874679B2 (en) 2016-03-02 2020-12-29 Bill & Melinda Gates Foundation Boron-containing small molecules
WO2017151489A1 (fr) 2016-03-02 2017-09-08 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore
AU2017229098B2 (en) 2016-03-07 2021-05-27 Agrofresh Inc. Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops
WO2017155877A1 (fr) 2016-03-07 2017-09-14 Agrofresh Inc. Administration vaporisée de pesticides
CN108884111A (zh) * 2016-05-09 2018-11-23 苏州科睿思制药有限公司 克立硼罗游离形式的晶型及其制备方法和用途
US11447506B2 (en) 2016-05-09 2022-09-20 Anacor Pharmaceuticals, Inc. Crystal forms of crisaborole in free form and preparation method and use thereof
UA124464C2 (uk) 2016-06-30 2021-09-22 Кьюпекс Біофарма, Інк. Похідні боронової кислоти та їх терапевтичні застосування
WO2018013655A1 (fr) 2016-07-12 2018-01-18 Pliva Hrvatska D.O.O. Formes à l'état solide de crisaborole
US10743232B1 (en) 2016-11-15 2020-08-11 Sprint Spectrum L.P. Controlling handover based on carrier-aggregation policies and UE capabilities
WO2018115362A1 (fr) 2016-12-22 2018-06-28 Laboratorios Lesvi, Sl Procédé de préparation de 4-[(1-hydroxy-1,3-dihydro -2,1-benzoxaborol-5-yl)oxy]benzonitrile (crisaborole)
GB201701583D0 (en) * 2017-01-31 2017-03-15 Drug Delivery Solutions Ltd Topical composition
WO2018150327A1 (fr) * 2017-02-14 2018-08-23 Wavelength Enterprises Ltd Procédé de production de crisaborole
EP3576747A4 (fr) * 2017-03-09 2020-12-16 The Penn State Research Foundation Petites molécules contenant du bore pour inhiber l'activité d'une protéine tyrosine phosphatase de type récepteur
WO2018207216A1 (fr) 2017-05-12 2018-11-15 Biophore India Pharmaceuticals Pvt. Ltd. Procédé de préparation de 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile (crisaborole)
US10865217B2 (en) 2017-05-23 2020-12-15 Msn Laboratories Private Limited, R & D Center Process for the preparation of 5-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and polymorphs thereof
CA3078627A1 (fr) 2017-10-11 2019-04-18 Qpex Biopharma, Inc. Derives d'acide boronique et synthese de ces derniers
EP3704100B1 (fr) 2017-11-02 2023-08-30 Halcyon Labs Private Limited Nouveau procédé de préparation de tavaborole et de ses intermédiaires
CN111655035A (zh) 2017-11-30 2020-09-11 博瑞金股份有限公司 苯并氧杂硼杂环戊烯化合物和其制剂
US10329311B1 (en) 2017-12-21 2019-06-25 Olon S.P.A. Process for the preparation of crisaborole
CN108148085B (zh) 2018-01-04 2019-11-01 合肥医工医药股份有限公司 具有抑制磷酸二酯酶4的化合物、制法及其药物用途
MX2020007091A (es) 2018-01-09 2020-09-22 Halcyon Labs Private Ltd Proceso para la preparacion de crisaborola y sus intermediarios.
US10597410B2 (en) 2018-02-02 2020-03-24 Dipharma Francis S.R.L. Intermediates and process for the preparation of a crystalline form of a topical anti-inflammatory agent
CN108451898A (zh) * 2018-04-03 2018-08-28 苏州尚宜佳生物科技有限公司 一种克立硼罗温敏凝胶剂及其制备方法和应用
GB201809378D0 (en) * 2018-06-07 2018-07-25 Glaxosmithkline Ip Dev Ltd Novel compounds
CN108659024A (zh) * 2018-07-24 2018-10-16 武汉轻工大学 克立硼罗的制备方法
CN112384201A (zh) * 2018-07-31 2021-02-19 Mc2疗法有限公司 局部组合物
AU2019325436B2 (en) 2018-08-18 2023-10-26 5Metis, Inc. Solid forms of substituted benzoxaborole and compositions thereof
CN113166177A (zh) 2018-10-05 2021-07-23 辉瑞公司 含硼的pde4抑制剂
WO2020187803A1 (fr) 2019-03-20 2020-09-24 Rita Dobmeyer Composition pharmaceutique
CN110664756B (zh) * 2019-10-09 2020-11-17 吉林大学 一种小儿外伤喷雾剂及其制备方法
WO2022043936A1 (fr) 2020-08-31 2022-03-03 Pfizer Inc. Procédés de protection de l'arn
CN114644645B (zh) * 2022-03-08 2023-05-26 南京农业大学 3-吲哚取代苯硼唑类化合物及其制备方法和应用
WO2023246841A1 (fr) * 2022-06-23 2023-12-28 Shanghai Micurx Pharmaceutical Co., Ltd. Procédés et utilisations de composés de bore dans le traitement d'infections par mycobactéries non tuberculeuses et compositions pharmaceutiques pour le traitement de celles-ci

Family Cites Families (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2260336A (en) * 1939-10-16 1941-10-28 Dow Chemical Co Method of preparation of organic borates
US3686398A (en) 1970-07-20 1972-08-22 Chevron Res 10,9-boroxarophenanthrene as fungicides
GB1396904A (en) * 1972-08-11 1975-06-11 Ici Ltd Method for the control of micro-organisms
US4602011A (en) 1975-10-24 1986-07-22 Chapman Chemical Company Antimicrobial compositions and methods of using same
US4766113A (en) 1975-10-24 1988-08-23 Chapman Chemical Company Antimicrobial compositions and methods of using same
US4716035A (en) * 1985-05-24 1987-12-29 The Procter & Gamble Company Oral compositions and methods for treating gingivitis
US5962498A (en) * 1986-06-11 1999-10-05 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity
US4894220A (en) * 1987-01-30 1990-01-16 Colgate-Palmolive Company Antibacterial antiplaque oral composition
US4919934A (en) 1989-03-02 1990-04-24 Richardson-Vicks Inc. Cosmetic sticks
US5514696A (en) * 1992-05-06 1996-05-07 Bristol-Myers Squibb Co. Phenyl sulfonamide endothelin antagonists
SG47101A1 (en) * 1992-07-31 1998-03-20 Us Bioscience Crystalline amifostine compositions and methods for the preparation and use of same
US5348947A (en) * 1993-05-07 1994-09-20 American Cyanamid Company Diarylboron ester and thioester fungicidal agents
US5348948A (en) * 1993-05-07 1994-09-20 American Cyanamid Company 2,2-diaryl-1-(oxa and thia)-2a-azonia-2-borataacenaphthene fungicidal
US5594151A (en) * 1994-01-28 1997-01-14 Prolinx, Inc. Phenylboronic acid complexing reagents derived from aminosalicylic acid
GB9411587D0 (en) * 1994-06-09 1994-08-03 Zeneca Ltd Compound, composition and use
US5688258A (en) 1995-05-02 1997-11-18 The Procter & Gamble Company Disposable cover for an absorbent materials
US6083903A (en) * 1994-10-28 2000-07-04 Leukosite, Inc. Boronic ester and acid compounds, synthesis and uses
GB9500856D0 (en) * 1995-01-17 1995-03-08 Zeneca Ltd Composition and use
JPH09124620A (ja) * 1995-10-11 1997-05-13 Bristol Myers Squibb Co 置換ビフェニルスルホンアミドエンドセリン拮抗剤
US6766183B2 (en) 1995-11-22 2004-07-20 Medtronic Minimed, Inc. Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers
GB9604926D0 (en) * 1996-03-08 1996-05-08 Sandoz Ltd Organic compounds
EP0934307B1 (fr) * 1996-06-19 2011-04-27 Aventis Pharma Limited Composes azabicycliques substitues et leur utilisation en tant qu'inhibiteurs de la production de tnf et de la photodiesterase cyclique d'amp
US5831046A (en) * 1996-08-05 1998-11-03 Prolinx, Incorporated Boronic acid-contaning nucleic acid monomers
US6413751B1 (en) 1996-09-19 2002-07-02 The Board Of Trustees Of The Leland Stanford Jr. University DNA adenine methyltransferases and uses thereof
WO1998024753A1 (fr) 1996-12-02 1998-06-11 Chisso Corporation Derives de nitro-alcool actifs optiquement, derives d'amino-alcool actifs optiquement et leur procede de preparation
US6221640B1 (en) 1997-05-14 2001-04-24 Cubist Pharmaceuticals, Inc. Enterococcal aminoacyl-trna synthetase proteins, nucleic acids and strains comprising same
US6140328A (en) 1997-12-12 2000-10-31 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
DE19829947A1 (de) 1998-07-04 2000-01-05 Bayer Ag Elektrolumineszierende Anordnungen mit Bor-Chelaten
US6462036B1 (en) 1998-11-06 2002-10-08 Basf Aktiengesellschaft Tricyclic pyrazole derivatives
SK5282001A3 (en) 1998-11-06 2002-01-07 Knoll Gmbh Tricyclic pyrazole derivatives
EP1155698A4 (fr) 1999-01-29 2003-01-15 Nitto Kasei Co Ltd Composes organobores presentant une activite de coccidiostats
WO2000075142A2 (fr) 1999-05-25 2000-12-14 The Penn State Research Foundation Inhibiteurs de methyltransferase d'adn
US6306628B1 (en) * 1999-08-25 2001-10-23 Ambergen, Incorporated Methods for the detection, analysis and isolation of Nascent proteins
EP1767629B1 (fr) 1999-08-25 2011-04-20 Ambergen, Inc. Techniques de détection, d'analyse et d'isolation de nouvelles protéines
US6921763B2 (en) * 1999-09-17 2005-07-26 Abbott Laboratories Pyrazolopyrimidines as therapeutic agents
US6369098B1 (en) * 1999-10-05 2002-04-09 Bethesda Pharmaceuticals, Inc. Dithiolane derivatives
EP1250142A4 (fr) 2000-01-06 2007-07-11 Marantech Holding Llc Compositions electroactives multivalentes et procedes de fabrication et d'utilisation de telles compositions
US6521619B2 (en) * 2000-06-29 2003-02-18 Icos Corporation Aryl phenylcyclopropyl sulfide derivatives and their use as cell adhesion inhibiting anti-inflammatory and immune suppressive agents
EP1303625A2 (fr) * 2000-07-14 2003-04-23 Zycos Inc. Composes en rapport avec alpha-msh et methodes d'utilisation
CA2428191A1 (fr) 2000-11-07 2002-05-30 Bristol-Myers Squibb Company Derives d'acide utiles comme inhibiteurs de serines proteases
EP1339725B1 (fr) 2000-11-30 2006-11-22 The Penn State Research Foundation Inhibiteurs des adn methyltransferases
DE10110051C2 (de) * 2001-03-02 2003-07-03 Clariant Gmbh Verfahren zur Herstellung von Boron- und Borinsäuren
EP1383731B1 (fr) 2001-04-06 2009-08-05 Biocryst Pharmaceuticals, Inc. Composes biaryle utilises comme inhibiteurs de serine protease
GB0117645D0 (en) * 2001-07-19 2001-09-12 Isis Innovation Therapeutic stratergies for prevention and treatment of alzheimers disease
DE10143979A1 (de) * 2001-09-07 2003-03-27 Clariant Gmbh Verfahren zur Herstellung von Bisallylboranen und nicht-aromatischen Boronsäuren
JPWO2003033002A1 (ja) * 2001-10-11 2005-02-03 御子柴　克彦 細胞内カルシウム濃度上昇抑制剤
CN1325504C (zh) 2002-01-10 2007-07-11 宾夕法尼亚州研究基金会 制备二芳基硼酸烷基酯和络合的二芳基硼酸的方法
EP1578362A4 (fr) * 2002-07-09 2008-11-05 Point Therapeutics Inc Polytherapie a base de composes de boroproline
CA2504941C (fr) 2002-11-08 2012-06-26 Neurogen Corporation 6-arylpyridines substituees en position 3
WO2004050585A1 (fr) 2002-12-02 2004-06-17 Solvias Ag Hydrogenation catalytique de doubles liaisons carbone-heteroatome
NZ540870A (en) * 2002-12-18 2008-09-26 Anacor Pharmaceuticals Inc Antibiotics containing borinic acid complexes and methods of use
US7390806B2 (en) * 2002-12-18 2008-06-24 Anacor Pharmaceuticals, Inc. Antibiotics containing borinic acid complexes and methods of use
CA2519107A1 (fr) 2003-03-14 2004-09-23 Astrazeneca Ab Triazolones fusionnees et utilisations de celles-ci
US20050125852A1 (en) * 2003-05-09 2005-06-09 Sugen, Inc. Novel kinases
US7465836B2 (en) * 2003-06-16 2008-12-16 Anacor Pharmaceuticals, Inc. Hydrolytically-resistant boron-containing therapeutics and methods of use
JP2005022986A (ja) * 2003-06-30 2005-01-27 Sankyo Co Ltd Ｅｄｇ受容体拮抗作用を有するアルキン誘導体
NZ544244A (en) 2003-07-03 2008-10-31 Hoffmann La Roche Dual NK1/NK3 antagonists for treating schizophrenia
CA2552101A1 (fr) 2003-12-29 2005-07-21 3M Innovative Properties Company Composes de cycles accoles imidazo de piperazine, [1,4]diazepane, [1,4]diazocane, et [1,5]diazocane
WO2005112970A2 (fr) * 2004-05-12 2005-12-01 The Brigham And Women's Hospital, Inc. Utilisation de gelsoline pour le traitement d'infections
AR049915A1 (es) 2004-06-14 2006-09-13 Anacor Pharmaceuticals Inc Compuestos con contenido de boro y metodos de uso de los mismos
KR100624238B1 (ko) 2004-06-22 2006-09-19 한국화학연구원 알파-아릴메톡시아크릴레이트 유도체를 함유하는 대사성골 질환의 예방 및 치료용 약학 조성물
WO2006062731A1 (fr) 2004-11-19 2006-06-15 University Of North Texas Health Science Center At Fort Worth Utilisation de la phenanthroline et de ses derives pour abaisser la tension intraoculaire d'un oeil affecte
GB0501944D0 (en) 2005-01-31 2005-03-09 Univ Cambridge Tech Compounds for use in chemical detection and/or quantitation
HUE054365T2 (hu) * 2005-02-16 2021-09-28 Anacor Pharmaceuticals Inc Bór-ftalidok terápiás alkalmazásra
US7767657B2 (en) * 2005-02-16 2010-08-03 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
EP1856113B1 (fr) 2005-03-08 2016-01-06 Agency for Science, Technology and Research Catalyseurs chiraux a base de bisoxazoline
UY29449A1 (es) * 2005-03-30 2006-10-02 Astion Dev As Tratamiento de enfermedades dermatólogicas y del prurito.
US20080234229A1 (en) 2005-08-18 2008-09-25 Auspex Pharmaceuticals, Inc. Novel Therapeutic Agents for the Treatment of Cancer, Metabolic Diseases and Skin Disorders
RU2642628C2 (ru) 2006-02-16 2018-01-25 Анакор Фармасьютикалз, Инк. Бор-содержащие малые молекулы в качестве противовоспалительных средств
US20070286822A1 (en) * 2006-06-12 2007-12-13 Anacor Pharmaceuticals Inc. Compounds for the Treatment of Periodontal Disease
RU2008152367A (ru) 2006-06-12 2010-07-20 Анакор Фармасьютикалз, Инк. (Us) Соединения для лечения периодонтального заболевания
KR100848491B1 (ko) 2007-01-16 2008-07-28 영진약품공업주식회사 베타아미노기를 갖는 2-싸이아졸리딘 유도체, 이의약학적으로 허용 가능한 염 및 이의 제조 방법
JO3396B1 (ar) 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون
KR100895300B1 (ko) 2007-07-20 2009-05-07 한국전자통신연구원 생체신호 측정의복과 생체신호 처리시스템
EP2187893A4 (fr) 2008-03-06 2012-02-22 Anacor Pharmaceuticals Inc Petites molécules contenant du bore utilisées en tant qu'agents anti-inflammatoires
KR20150065941A (ko) 2008-03-06 2015-06-15 아나코르 파마슈티칼스 인코포레이티드 소염제로써 붕소가 함유된 소분자
WO2009140309A2 (fr) 2008-05-12 2009-11-19 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore
WO2010028005A1 (fr) 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore
WO2010045505A1 (fr) 2008-10-15 2010-04-22 Anacor Pharmaceuticals, Inc Petites molécules contenant du bore en tant qu’agents antiprotozoaires
US9493489B2 (en) 2008-10-15 2016-11-15 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agents
AR088669A1 (es) * 2011-11-21 2014-06-25 Lilly Co Eli Derivados de dihidrodibenzo[c][1,2]oxaborol y dihidroisoxazol utiles para el control de ectoparasitos
AR088668A1 (es) * 2011-11-21 2014-06-25 Lilly Co Eli Moleculas pequeñas que contienen boro

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PT2343304E (pt) 2015-08-26
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US20190048026A1 (en) 2019-02-14
RU2016145916A3 (fr) 2020-07-21
US20190330245A1 (en) 2019-10-31
PL1853251T3 (pl) 2013-09-30
EP1853251A4 (fr) 2010-01-13
LUC00157I2 (fr) 2021-07-06
HUE040060T2 (hu) 2019-02-28
KR20070112390A (ko) 2007-11-23
SI2987796T1 (sl) 2018-11-30
JP2010248265A (ja) 2010-11-04
CY2020027I2 (el) 2021-01-27
LTPA2020524I1 (lt) 2020-09-10
AU2006214247B2 (en) 2010-08-05
CA2597982A1 (fr) 2006-08-24
AU2006214247A1 (en) 2006-08-24
IL185080A (en) 2012-07-31
JP2016020374A (ja) 2016-02-04
HUS2000019I1 (hu) 2020-07-28
US7582621B2 (en) 2009-09-01
RU2007134429A (ru) 2009-03-27
PT3424932T (pt) 2021-05-19
AU2010203096C1 (en) 2012-09-20
HK1109735A1 (en) 2008-06-20
LUC00157I1 (fr) 2020-06-08
PT2987796T (pt) 2018-10-18
KR20100105869A (ko) 2010-09-30
EP2343304B1 (fr) 2015-06-10
ES2686981T3 (es) 2018-10-23
PL2987796T3 (pl) 2018-12-31
CN101914109A (zh) 2010-12-15
CN101160124A (zh) 2008-04-09
US20130244980A1 (en) 2013-09-19
BRPI0608431B1 (pt) 2020-09-15
ES2872962T3 (es) 2021-11-03
PT1853251E (pt) 2013-07-19
JP2017105826A (ja) 2017-06-15
BRPI0608431A2 (pt) 2009-12-29
US20210070780A1 (en) 2021-03-11
NZ598441A (en) 2013-07-26
CA2597982C (fr) 2014-07-08
ZA200905950B (en) 2010-11-24
NZ578297A (en) 2010-11-26
RU2016145916A (ru) 2018-05-23
US20170066788A1 (en) 2017-03-09
KR20130095330A (ko) 2013-08-27
KR101337045B1 (ko) 2013-12-05
RU2010133524A (ru) 2012-02-20
BRPI0608431B8 (pt) 2021-05-25
AU2010203096A1 (en) 2010-08-12
MX369262B (es) 2019-11-04
US20110319361A1 (en) 2011-12-29
NZ560448A (en) 2009-08-28
ZA200707408B (en) 2009-11-25
IL207156A (en) 2014-04-30
KR101426220B1 (ko) 2014-08-05
US8039451B2 (en) 2011-10-18
CN101914109B (zh) 2014-07-23
AU2010203096B2 (en) 2010-12-02
KR20130100019A (ko) 2013-09-06
JP6046876B2 (ja) 2016-12-21
DK2343304T3 (en) 2015-06-29
EP3424932A1 (fr) 2019-01-09

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