EP2187893A4 - Petites molécules contenant du bore utilisées en tant qu'agents anti-inflammatoires - Google Patents

Petites molécules contenant du bore utilisées en tant qu'agents anti-inflammatoires

Info

Publication number
EP2187893A4
EP2187893A4 EP09700012A EP09700012A EP2187893A4 EP 2187893 A4 EP2187893 A4 EP 2187893A4 EP 09700012 A EP09700012 A EP 09700012A EP 09700012 A EP09700012 A EP 09700012A EP 2187893 A4 EP2187893 A4 EP 2187893A4
Authority
EP
European Patent Office
Prior art keywords
boron
small molecules
inflammatory agents
containing small
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09700012A
Other languages
German (de)
English (en)
Other versions
EP2187893A2 (fr
Inventor
Tsutomu Akama
Yong-Kang Zhang
Charles Z Ding
Jacob J Plattner
Kirk R Maples
Yvonne Freund
Virginia Sanders
Yi Xia
Stephen J Baker
James A Niemann
Xiaosong Lu
Marcelo Sales
Rashmi Sharma
Rajeshwar Singh
Robert Jacobs
Daitao Chen
Michael Richard Kevin Alley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anacor Pharmaceuticals Inc
Original Assignee
Anacor Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anacor Pharmaceuticals Inc filed Critical Anacor Pharmaceuticals Inc
Priority to EP17158536.7A priority Critical patent/EP3246034A1/fr
Priority to EP12178640.4A priority patent/EP2564857B1/fr
Publication of EP2187893A2 publication Critical patent/EP2187893A2/fr
Publication of EP2187893A4 publication Critical patent/EP2187893A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
EP09700012A 2008-03-06 2009-03-05 Petites molécules contenant du bore utilisées en tant qu'agents anti-inflammatoires Withdrawn EP2187893A4 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP17158536.7A EP3246034A1 (fr) 2008-03-06 2009-03-05 Petites molécules contenant du bore en tant qu'agents anti-inflammatoires
EP12178640.4A EP2564857B1 (fr) 2008-03-06 2009-03-05 Petites molécules contenant du bore en tant qu'agents anti-inflammatoires

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US3437108P 2008-03-06 2008-03-06
US5263708P 2008-05-12 2008-05-12
US9440608P 2008-09-04 2008-09-04
US10599008P 2008-10-16 2008-10-16
US11090308P 2008-11-03 2008-11-03
US14370009P 2009-01-09 2009-01-09
US14873109P 2009-01-30 2009-01-30
PCT/US2009/036250 WO2009111676A2 (fr) 2008-03-06 2009-03-05 Petites molécules contenant du bore utilisées en tant qu'agents anti-inflammatoires

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP17158536.7A Division EP3246034A1 (fr) 2008-03-06 2009-03-05 Petites molécules contenant du bore en tant qu'agents anti-inflammatoires
EP12178640.4A Division EP2564857B1 (fr) 2008-03-06 2009-03-05 Petites molécules contenant du bore en tant qu'agents anti-inflammatoires

Publications (2)

Publication Number Publication Date
EP2187893A2 EP2187893A2 (fr) 2010-05-26
EP2187893A4 true EP2187893A4 (fr) 2012-02-22

Family

ID=41056660

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09700012A Withdrawn EP2187893A4 (fr) 2008-03-06 2009-03-05 Petites molécules contenant du bore utilisées en tant qu'agents anti-inflammatoires

Country Status (2)

Country Link
EP (1) EP2187893A4 (fr)
WO (1) WO2009111676A2 (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767657B2 (en) 2005-02-16 2010-08-03 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
HUE054365T2 (hu) 2005-02-16 2021-09-28 Anacor Pharmaceuticals Inc Bór-ftalidok terápiás alkalmazásra
RU2642628C2 (ru) 2006-02-16 2018-01-25 Анакор Фармасьютикалз, Инк. Бор-содержащие малые молекулы в качестве противовоспалительных средств
KR20150065941A (ko) 2008-03-06 2015-06-15 아나코르 파마슈티칼스 인코포레이티드 소염제로써 붕소가 함유된 소분자
EP2348863A4 (fr) 2008-09-04 2012-03-07 Anacor Pharmaceuticals Inc Petites molécules contenant du bore
WO2010028005A1 (fr) 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore
US9493489B2 (en) 2008-10-15 2016-11-15 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agents
WO2010080558A1 (fr) 2008-12-17 2010-07-15 Anacor Pharmaceuticals, Inc. Formes polymorphiques du (s)-3-aminométhyl-7-(3-hydroxy-propoxy)-3h-benzo[c][1,2]oxaborol-1-ol
JP2013500974A (ja) 2009-07-28 2013-01-10 アナコール ファーマシューティカルズ，インコーポレイテッド 三置換ホウ素含有分子
AP4039A (en) 2009-08-14 2017-02-28 Daitao Chen Boron-containing small molecules as antiprotozoal agents
MX2012002031A (es) 2009-08-19 2012-07-04 Anacor Pharmaceuticals Inc Moleculas pequeñas que contienen boro como agentes antiprotozoarios.
WO2011049971A1 (fr) 2009-10-20 2011-04-28 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore comme agents antiprotozoaires
WO2011060199A1 (fr) 2009-11-11 2011-05-19 Anacor Pharmaceuticals, Inc. Petites molecules contenant du bore
WO2011063293A1 (fr) * 2009-11-20 2011-05-26 Anacor Pharmaceuticals, Inc. Petites molécules contenant du bore en tant qu'agents antihelminthes
WO2011094450A1 (fr) * 2010-01-27 2011-08-04 Anacor Pharmaceuticals, Inc Petites molecules contenant du bore
WO2011116348A1 (fr) 2010-03-19 2011-09-22 Anacor Pharmaceuticals, Inc. Petites molécules borées en tant qu'agent anti-protozoaire
HRP20211762T1 (hr) 2010-09-07 2022-02-18 Anacor Pharmaceuticals, Inc. Derivati benzoksaborola za liječenje bakterijskih infekcija
WO2013028371A1 (fr) 2011-08-19 2013-02-28 Glaxo Group Limited Composés benzofuranes pour le traitement d'infections par le virus de l'hépatite c
JP5927686B1 (ja) 2013-01-30 2016-06-01 アグロフレッシュ インコーポレイテッド 食肉、植物または植物の一部分に対する揮発性抗菌剤としてのベンゾオキサボロールの使用
US10070649B2 (en) 2013-01-30 2018-09-11 Agrofresh Inc. Volatile applications against pathogens
US9585396B2 (en) 2013-01-30 2017-03-07 Agrofresh Inc. Volatile applications against pathogens
US8669207B1 (en) 2013-01-30 2014-03-11 Dow Agrosciences, Llc. Compounds and compositions
US11039617B2 (en) 2013-01-30 2021-06-22 Agrofresh Inc. Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
WO2016001834A1 (fr) 2014-07-01 2016-01-07 Daiichi Sankyo Company, Limited Benzoxaboroles tricycliques en tant qu'agents antibactériens
WO2017089347A1 (fr) 2015-11-25 2017-06-01 Inserm (Institut National De La Sante Et De La Recherche Medicale) Procédés et compositions pharmaceutiques pour le traitement de mélanomes résistant aux inhibiteurs de braf
SI3383363T1 (sl) 2015-11-30 2021-03-31 Anacor Pharmaceuticals, Inc. Topične farmacevtske formulacije za zdravljenje vnetnih bolezenskih stanj
AU2017229098B2 (en) 2016-03-07 2021-05-27 Agrofresh Inc. Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops
US11447506B2 (en) 2016-05-09 2022-09-20 Anacor Pharmaceuticals, Inc. Crystal forms of crisaborole in free form and preparation method and use thereof
WO2017203514A1 (fr) * 2016-05-26 2017-11-30 Perrigo Api Ltd Polymorphes de crisaborole et procédés pour les produire
EP3609504A4 (fr) 2017-03-01 2021-03-03 Anacor Pharmaceuticals, Inc. Nouveaux analogues d'oxaborole et utilisations de ces derniers
WO2018207216A1 (fr) * 2017-05-12 2018-11-15 Biophore India Pharmaceuticals Pvt. Ltd. Procédé de préparation de 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile (crisaborole)
US10865217B2 (en) 2017-05-23 2020-12-15 Msn Laboratories Private Limited, R & D Center Process for the preparation of 5-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and polymorphs thereof
CN111655035A (zh) 2017-11-30 2020-09-11 博瑞金股份有限公司 苯并氧杂硼杂环戊烯化合物和其制剂
AU2019325436B2 (en) 2018-08-18 2023-10-26 5Metis, Inc. Solid forms of substituted benzoxaborole and compositions thereof
CN113166177A (zh) 2018-10-05 2021-07-23 辉瑞公司 含硼的pde4抑制剂
WO2020179859A1 (fr) 2019-03-06 2020-09-10 第一三共株式会社 Dérivé de pyrrolopyrazole
CN112174989B (zh) * 2019-07-02 2023-06-20 江西同和药业股份有限公司 一种克立硼罗的制备方法
WO2022043936A1 (fr) 2020-08-31 2022-03-03 Pfizer Inc. Procédés de protection de l'arn
WO2024038090A1 (fr) * 2022-08-18 2024-02-22 Mitodicure Gmbh Utilisation de composés de benzofurane et de benzoxazole substitués pour le traitement et la prévention de maladies associées à la fatigue chronique, à l'épuisement et/ou à l'intolérance à l'effort
CN116239498B (zh) * 2023-05-11 2023-07-21 北京元延医药科技股份有限公司 制备克立硼罗中间体的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060234981A1 (en) * 2005-02-16 2006-10-19 Anacor Pharmaceuticals Boron-containing small molecules

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596985B2 (en) * 2000-02-22 2003-07-22 Rioch Company, Ltd. Multi-beam scanning device, multi-beam scanning method, light source device, and image forming apparatus
UY29449A1 (es) * 2005-03-30 2006-10-02 Astion Dev As Tratamiento de enfermedades dermatólogicas y del prurito.
RU2642628C2 (ru) * 2006-02-16 2018-01-25 Анакор Фармасьютикалз, Инк. Бор-содержащие малые молекулы в качестве противовоспалительных средств

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060234981A1 (en) * 2005-02-16 2006-10-19 Anacor Pharmaceuticals Boron-containing small molecules

Also Published As

Publication number Publication date
WO2009111676A8 (fr) 2010-09-30
WO2009111676A3 (fr) 2010-04-01
EP2187893A2 (fr) 2010-05-26
WO2009111676A2 (fr) 2009-09-11

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Inventor name: ALLEY, MICHAEL RICHARD KEVIN

Inventor name: CHEN, DAITAO

Inventor name: JACOBS, ROBERT

Inventor name: SINGH, RAJESHWAR

Inventor name: SHARMA, RASHMI

Inventor name: SALES, MARCELO

Inventor name: LU, XIAOSONG

Inventor name: NIEMANN, JAMES A.

Inventor name: BAKER, STEPHEN J.

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Inventor name: SANDERS, VIRGINIA

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Inventor name: MAPLES, KIRK R.

Inventor name: PLATTNER, JACOB J.

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