HK1139652A1 - Biaryl ether urea compounds - Google Patents
Biaryl ether urea compoundsInfo
- Publication number
- HK1139652A1 HK1139652A1 HK10105310.0A HK10105310A HK1139652A1 HK 1139652 A1 HK1139652 A1 HK 1139652A1 HK 10105310 A HK10105310 A HK 10105310A HK 1139652 A1 HK1139652 A1 HK 1139652A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- urea compounds
- ether urea
- biaryl ether
- biaryl
- compounds
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82996606P | 2006-10-18 | 2006-10-18 | |
US96521007P | 2007-08-17 | 2007-08-17 | |
PCT/IB2007/003202 WO2008047229A2 (fr) | 2006-10-18 | 2007-10-05 | Composés d'urée de bisaryle éther |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1139652A1 true HK1139652A1 (en) | 2010-09-24 |
Family
ID=39314409
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10105310.0A HK1139652A1 (en) | 2006-10-18 | 2010-05-31 | Biaryl ether urea compounds |
Country Status (39)
Country | Link |
---|---|
US (1) | US8044052B2 (fr) |
EP (1) | EP2076508B1 (fr) |
JP (1) | JP4434313B2 (fr) |
KR (1) | KR101181194B1 (fr) |
CN (1) | CN101595102B (fr) |
AP (1) | AP2780A (fr) |
AR (1) | AR063331A1 (fr) |
AT (1) | ATE493984T1 (fr) |
AU (1) | AU2007311591B2 (fr) |
BR (1) | BRPI0717596B8 (fr) |
CA (1) | CA2663984C (fr) |
CL (1) | CL2007003000A1 (fr) |
CR (2) | CR10701A (fr) |
CY (1) | CY1111170T1 (fr) |
DE (1) | DE602007011793D1 (fr) |
DK (1) | DK2076508T3 (fr) |
EA (1) | EA015488B1 (fr) |
ES (1) | ES2357340T3 (fr) |
GE (1) | GEP20125425B (fr) |
HK (1) | HK1139652A1 (fr) |
HN (1) | HN2007000407A (fr) |
HR (1) | HRP20110158T1 (fr) |
IL (1) | IL197664A (fr) |
MA (1) | MA30801B1 (fr) |
ME (1) | ME01308B (fr) |
MX (1) | MX2009004233A (fr) |
MY (1) | MY145460A (fr) |
NO (1) | NO342266B1 (fr) |
NZ (1) | NZ575624A (fr) |
PE (1) | PE20081265A1 (fr) |
PL (1) | PL2076508T3 (fr) |
PT (1) | PT2076508E (fr) |
RS (2) | RS20090154A (fr) |
SI (1) | SI2076508T1 (fr) |
TN (1) | TN2009000138A1 (fr) |
TW (1) | TWI404715B (fr) |
UY (1) | UY30649A1 (fr) |
WO (1) | WO2008047229A2 (fr) |
ZA (1) | ZA200902548B (fr) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2937341T3 (en) | 2004-12-30 | 2017-09-11 | Janssen Pharmaceutica Nv | 4- (BENZYL) -PIPERAZINE-1-CARBOXYLIC ACID PHENYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF FATTY ACID HYDROLASE (FAAH) FOR TREATING ANALYSIS, PAIN AND OTHER CONDITIONS |
JO3598B1 (ar) | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
PT2076508E (pt) | 2006-10-18 | 2011-03-07 | Pfizer Prod Inc | Compostos de ureia de éter biarílico |
PE20091838A1 (es) | 2008-04-09 | 2009-12-18 | Infinity Pharmaceuticals Inc | Inhibidores de amida hidrolasa de acido graso |
JP2011518143A (ja) * | 2008-04-17 | 2011-06-23 | ファイザー・インク | Faah阻害剤として有用なエーテルベンジリデンピペリジンアリールカルボキサミド化合物 |
JP2011518142A (ja) * | 2008-04-17 | 2011-06-23 | ファイザー・インク | Faah阻害剤として有用なエーテルベンジリデンピペリジン5員アリールカルボキサミド化合物 |
EP2276737A1 (fr) * | 2008-04-17 | 2011-01-26 | Pfizer Inc. | Composés aryl carboxamides de 4-[3-(aryloxy)benzylidène]-3-méthyl pipéridine utiles comme inhibiteurs de la faah |
US20110053950A1 (en) * | 2008-04-17 | 2011-03-03 | Pfizer, Inc. | 4-benzylidene-3-methylpiperidine aryl carboxamide compounds useful as faah inhibitors |
JP2011518145A (ja) * | 2008-04-17 | 2011-06-23 | ファイザー・インク | Faah阻害剤として有用な4−[3−(アリールオキシ)ベンジリデン]−3−メチルピペリジン5員アリールカルボキサミド化合物 |
US8461159B2 (en) | 2008-11-25 | 2013-06-11 | Jannsen Pharmaceutica BV | Heteroaryl-substituted urea modulators of fatty acid amide hydrolase |
WO2010068452A1 (fr) | 2008-11-25 | 2010-06-17 | Janssen Pharmaceutica Nv | Modulateurs à base d’urée à substitution hétéroaryle d'amide d’acide gras hydrolase |
WO2010064597A1 (fr) * | 2008-12-01 | 2010-06-10 | 武田薬品工業株式会社 | Dérivé de pipéridine |
BRPI1006128A2 (pt) | 2009-01-12 | 2016-11-01 | Cagen Inc | derivados de sulfonamida |
ES2493916T3 (es) | 2009-04-07 | 2014-09-12 | Infinity Pharmaceuticals, Inc. | Inhibidores de hidrolasa de amida de ácidos grasos |
US8541581B2 (en) | 2009-04-07 | 2013-09-24 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
US9062116B2 (en) | 2009-04-23 | 2015-06-23 | Infinity Pharmaceuticals, Inc. | Anti-fatty acid amide hydrolase-2 antibodies and uses thereof |
US8765735B2 (en) | 2009-05-18 | 2014-07-01 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
US8927551B2 (en) | 2009-05-18 | 2015-01-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
US9149465B2 (en) | 2009-05-18 | 2015-10-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
US8901111B2 (en) | 2009-06-05 | 2014-12-02 | Janssen Pharmaceutica Nv | Aryl-substituted heterocyclic urea modulators of fatty acid amide hydrolase |
WO2010141817A1 (fr) | 2009-06-05 | 2010-12-09 | Janssen Pharmaceutica Nv | Modulateurs d'amide d'acide gras hydrolase de type diamine urée spirocyclique substituée par un groupe hétéroaryle |
EP2476682B1 (fr) | 2009-09-09 | 2017-04-26 | Sumitomo Dainippon Pharma Co., Ltd. | Dérivé de 8-oxodihydropurine |
WO2011077313A1 (fr) | 2009-12-22 | 2011-06-30 | Pfizer Inc. | Pipéridinecarboxamides en tant qu'inhibiteurs de mpges - 1 |
WO2011085216A2 (fr) | 2010-01-08 | 2011-07-14 | Ironwood Pharmaceuticals, Inc. | Utilisation d'inhibiteurs de faah pour traiter la maladie de parkinson et le syndrome des jambes sans repos |
MX336742B (es) | 2010-02-03 | 2016-01-29 | Infinity Pharmaceuticals Inc | Inhibidores de amida hidrolasa de acido graso. |
CA2789606A1 (fr) | 2010-02-25 | 2011-09-01 | Pfizer Limited | Analogues peptidiques en tant qu'agonistes des recepteurs opioides |
WO2011123719A2 (fr) | 2010-03-31 | 2011-10-06 | Ironwood Pharmaceuticals, Inc. | Utilisation d'inhibiteurs de faah pour le traitement des douleurs abdominales, viscérales et pelviennes |
UA108233C2 (uk) | 2010-05-03 | 2015-04-10 | Модулятори активності гідролази амідів жирних кислот | |
JP5830534B2 (ja) | 2010-07-09 | 2015-12-09 | ファイザー・リミテッドPfizer Limited | 化合物 |
US9096558B2 (en) | 2010-07-09 | 2015-08-04 | Pfizer Limited | N-sulfonylbenzamide compounds |
CA2804716A1 (fr) | 2010-07-12 | 2012-01-19 | Pfizer Limited | Composes chimiques |
EP2593432B1 (fr) | 2010-07-12 | 2014-10-22 | Pfizer Limited | Dérivés de n-sulfonylbenzamide utiles comme inhibiteurs du canal sodique voltage-dépendant |
US8772343B2 (en) | 2010-07-12 | 2014-07-08 | Pfizer Limited | Chemical compounds |
ES2532357T3 (es) | 2010-07-12 | 2015-03-26 | Pfizer Limited | Derivados de sulfonamida como inhibidores de Nav1.7 para el tratamiento del dolor |
EP2593431B1 (fr) | 2010-07-12 | 2014-11-19 | Pfizer Limited | N-sulfonylbenzamides comme inhibiteurs des canaux sodiques voltage-dépendant |
WO2012095781A1 (fr) | 2011-01-13 | 2012-07-19 | Pfizer Limited | Dérivés d'indazole comme inhibiteurs des canaux sodiques |
BR112013025792A2 (pt) | 2011-04-05 | 2018-04-24 | Pfizer Ltd | Inibidores de quinase relacionada à pirrolo[2,3-d] pirimidina tropomisina |
US8957025B2 (en) | 2011-07-13 | 2015-02-17 | Pfizer Inc. | Enkephalin analogues |
EP2758375A1 (fr) * | 2011-09-23 | 2014-07-30 | Advinus Therapeutics Limited | Composés amides, compositions et applications de ceux-ci |
WO2013054185A1 (fr) | 2011-10-13 | 2013-04-18 | Pfizer, Inc. | Dérivés de pyrimidine et de pyridine utiles en thérapie |
EP2771335A2 (fr) | 2011-10-26 | 2014-09-03 | Pfizer Limited | Composés chimiques |
CN106220572B (zh) | 2011-10-28 | 2019-12-13 | 因西必泰克新有限公司 | 哒嗪衍生物的化合物、用途、组合物和试剂盒及制备方法 |
EP2791108B1 (fr) | 2011-12-15 | 2016-07-27 | Pfizer Limited | Dérivés sulfonamides |
WO2013093688A1 (fr) | 2011-12-19 | 2013-06-27 | Pfizer Limited | Dérivés sulfonamides et leur utilisation en tant qu'inhibiteurs de vgsc |
WO2013102826A1 (fr) | 2012-01-04 | 2013-07-11 | Pfizer Limited | N-aminosulfonylbenzamides |
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