HK1135693A1 - Camptothecin derivatives with antitumor activity - Google Patents

Camptothecin derivatives with antitumor activity

Info

Publication number
HK1135693A1
HK1135693A1 HK10100457.4A HK10100457A HK1135693A1 HK 1135693 A1 HK1135693 A1 HK 1135693A1 HK 10100457 A HK10100457 A HK 10100457A HK 1135693 A1 HK1135693 A1 HK 1135693A1
Authority
HK
Hong Kong
Prior art keywords
antitumor activity
camptothecin derivatives
antitumor
derivatives
camptothecin
Prior art date
Application number
HK10100457.4A
Other languages
English (en)
Inventor
Gabriele Fontana
Ezio Bombardelli
Carla Manzotti
Arturo Battaglia
Cristian Samori
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of HK1135693A1 publication Critical patent/HK1135693A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
HK10100457.4A 2006-07-26 2010-01-15 Camptothecin derivatives with antitumor activity HK1135693A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001475A ITMI20061475A1 (it) 2006-07-26 2006-07-26 Derivati della camptotecina ad attivita antitumorale
PCT/EP2007/006218 WO2008011992A1 (en) 2006-07-26 2007-07-12 Camptothecin derivatives with antitumor activity

Publications (1)

Publication Number Publication Date
HK1135693A1 true HK1135693A1 (en) 2010-06-11

Family

ID=38520867

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10100457.4A HK1135693A1 (en) 2006-07-26 2010-01-15 Camptothecin derivatives with antitumor activity

Country Status (22)

Country Link
US (1) US8076351B2 (xx)
EP (1) EP2044078B1 (xx)
JP (1) JP5198447B2 (xx)
KR (1) KR101398591B1 (xx)
CN (1) CN101495484B (xx)
AT (1) ATE482216T1 (xx)
AU (1) AU2007278587B2 (xx)
BR (1) BRPI0714669B8 (xx)
CA (1) CA2659050C (xx)
DE (1) DE602007009396D1 (xx)
DK (1) DK2044078T3 (xx)
ES (1) ES2350711T3 (xx)
HK (1) HK1135693A1 (xx)
IL (1) IL196654A (xx)
IT (1) ITMI20061475A1 (xx)
MX (1) MX2009000903A (xx)
NO (1) NO341743B1 (xx)
PL (1) PL2044078T3 (xx)
PT (1) PT2044078E (xx)
RU (1) RU2441009C2 (xx)
SI (1) SI2044078T1 (xx)
WO (1) WO2008011992A1 (xx)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2972955A (en) * 1957-03-21 1961-02-28 Richter Harald Submersible pump
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
US5637770A (en) * 1991-01-16 1997-06-10 Daiichi Pharmaceutical Co., Ltd. Hexa-cyclic compound
US5834479A (en) 1993-03-05 1998-11-10 Mayer; David J. Method and composition for alleviating pain
KR960029336A (ko) * 1995-01-09 1996-08-17 김충환 캄토테신 유도체, 그의 제조 방법 및 이를 함유하는 항암제
US5972955A (en) * 1995-06-06 1999-10-26 Dr. Reddy's Research Foundation Water soluble C-ring analogues of 20(S)-camptothecin
US6177439B1 (en) 1995-06-06 2001-01-23 Reddy's Research Foundation Water soluble analogues of 20(S)-camptothecin
US6214836B1 (en) * 1995-06-06 2001-04-10 Dr. Reddy's Research Foundation Water soluble analogues of 20(S)-camptothecin
JP3600248B2 (ja) * 1996-06-05 2004-12-15 ドクター・レディーズ・ラボラトリーズ・リミテッド ２０（ｓ）−カンプトテシンの新規な水溶性ｃ−環類似体
AU4822500A (en) 1999-05-04 2000-11-17 Bionumerik Pharmaceuticals, Inc. Novel highly lipophilic camptothecin analogs

Also Published As

Publication number Publication date
RU2009102229A (ru) 2010-07-27
ITMI20061475A1 (it) 2008-01-27
AU2007278587B2 (en) 2012-11-01
EP2044078A1 (en) 2009-04-08
IL196654A0 (en) 2009-11-18
PT2044078E (pt) 2010-11-18
US20100063082A1 (en) 2010-03-11
NO341743B1 (no) 2018-01-15
US8076351B2 (en) 2011-12-13
ATE482216T1 (de) 2010-10-15
JP5198447B2 (ja) 2013-05-15
MX2009000903A (es) 2009-02-04
DE602007009396D1 (en) 2010-11-04
CA2659050A1 (en) 2008-01-31
SI2044078T1 (sl) 2011-01-31
NO20090350L (no) 2009-01-23
WO2008011992A1 (en) 2008-01-31
IL196654A (en) 2015-03-31
DK2044078T3 (da) 2010-12-13
BRPI0714669B8 (pt) 2021-05-25
CA2659050C (en) 2014-09-23
CN101495484A (zh) 2009-07-29
BRPI0714669A2 (pt) 2013-04-24
ES2350711T3 (es) 2011-01-26
KR101398591B1 (ko) 2014-05-27
CN101495484B (zh) 2011-12-28
RU2441009C2 (ru) 2012-01-27
PL2044078T3 (pl) 2011-03-31
WO2008011992A8 (en) 2009-02-19
JP2010500970A (ja) 2010-01-14
KR20090040304A (ko) 2009-04-23
EP2044078B1 (en) 2010-09-22
AU2007278587A1 (en) 2008-01-31
BRPI0714669B1 (pt) 2020-11-17

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20210707