NO20090251L - Camptotecinderivater med antitumoraktivitet - Google Patents

Camptotecinderivater med antitumoraktivitet

Info

Publication number
NO20090251L
NO20090251L NO20090251A NO20090251A NO20090251L NO 20090251 L NO20090251 L NO 20090251L NO 20090251 A NO20090251 A NO 20090251A NO 20090251 A NO20090251 A NO 20090251A NO 20090251 L NO20090251 L NO 20090251L
Authority
NO
Norway
Prior art keywords
tumor activity
derivatives
camptotecin
camptotecin derivatives
activity
Prior art date
Application number
NO20090251A
Other languages
English (en)
Other versions
NO341812B1 (no
Inventor
Gabriele Fontana
Ezio Bombardelli
Carla Manzotti
Arturo Battaglia
Cristian Samori
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of NO20090251L publication Critical patent/NO20090251L/no
Publication of NO341812B1 publication Critical patent/NO341812B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

Nye camptotecinderivater som har antitumoraktivitet, prosessen for fremstilling derav, anvendelsen derav som antitumorlegemiddel og farmasøytiske sammensetninger inneholdende dem.
NO20090251A 2006-07-26 2009-01-16 Camptotecinderivater med antitumoraktivitet NO341812B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001473A ITMI20061473A1 (it) 2006-07-26 2006-07-26 Derivati della camptotecina ad attivita antitumorale
PCT/EP2007/006243 WO2008011994A1 (en) 2006-07-26 2007-07-13 Camptothecin derivatives with antitumor activity

Publications (2)

Publication Number Publication Date
NO20090251L true NO20090251L (no) 2009-01-16
NO341812B1 NO341812B1 (no) 2018-01-29

Family

ID=38668829

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090251A NO341812B1 (no) 2006-07-26 2009-01-16 Camptotecinderivater med antitumoraktivitet

Country Status (21)

Country Link
US (1) US8217053B2 (no)
EP (1) EP2044079B1 (no)
JP (1) JP5313894B2 (no)
KR (1) KR101412157B1 (no)
CN (1) CN101495486B (no)
AU (1) AU2007278500B2 (no)
BR (1) BRPI0714553B8 (no)
CA (1) CA2658900C (no)
DK (1) DK2044079T3 (no)
ES (1) ES2561356T3 (no)
HK (1) HK1135691A1 (no)
HU (1) HUE027890T2 (no)
IL (1) IL196653A (no)
IT (1) ITMI20061473A1 (no)
MX (1) MX2009000827A (no)
NO (1) NO341812B1 (no)
PL (1) PL2044079T3 (no)
PT (1) PT2044079E (no)
RU (1) RU2450008C2 (no)
SI (1) SI2044079T1 (no)
WO (1) WO2008011994A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2907824T (pt) 2012-10-11 2018-06-07 Daiichi Sankyo Co Ltd Conjugado de anticorpo-fármaco
WO2014061277A1 (ja) 2012-10-19 2014-04-24 第一三共株式会社 親水性構造を含むリンカーで結合させた抗体－薬物コンジュゲート
KR101586030B1 (ko) * 2014-01-22 2016-01-15 주식회사 엘지생활건강 캄프토테신을 유효성분으로 포함하는 체모 성장 억제용 조성물
KR102275925B1 (ko) 2014-01-31 2021-07-12 다이이찌 산쿄 가부시키가이샤 항-her2 항체-약물 접합체
HUE061408T2 (hu) 2015-06-29 2023-06-28 Daiichi Sankyo Co Ltd Eljárás antitest-gyógyszer konjugátum szelektív elõállítására
SG10201912575RA (en) 2016-12-12 2020-02-27 Daiichi Sankyo Co Ltd Combination of antibody-drug conjugate and immune checkpoint inhibitor
TWI780104B (zh) 2017-01-17 2022-10-11 日商第一三共股份有限公司 抗ｇｐｒ２０抗體及抗ｇｐｒ２０抗體-藥物結合物、以及其製造方法及用途
TWI794230B (zh) 2017-05-15 2023-03-01 日商第一三共股份有限公司 抗ｃｄｈ６抗體及抗ｃｄｈ６抗體-藥物結合物、以及其製造方法
SG11202001514XA (en) 2017-08-31 2020-03-30 Daiichi Sankyo Co Ltd Novel method for producing antibody-drug conjugate
CN111051330A (zh) 2017-08-31 2020-04-21 第一三共株式会社 抗体-药物缀合物的改进制备方法
US20210221910A1 (en) 2018-05-18 2021-07-22 Glycotope Gmbh Anti-muc1 antibody
US10568873B1 (en) * 2019-02-14 2020-02-25 United Arab Emirates University Safranal-sorafenib combination therapy for liver cancer
CN112905237A (zh) 2019-12-04 2021-06-04 北京百度网讯科技有限公司 指令预取方法、装置、设备和介质
CN112225745B (zh) * 2020-11-16 2021-10-12 烟台大学 一种具有抗肿瘤活性的异片螺素类化合物、制备方法及用途
CN117510515A (zh) * 2022-07-28 2024-02-06 明慧医药（杭州）有限公司 适用于抗体-药物偶联物的毒素分子

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4391909A (en) * 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US5972955A (en) * 1995-06-06 1999-10-26 Dr. Reddy's Research Foundation Water soluble C-ring analogues of 20(S)-camptothecin
FR2757515B1 (fr) * 1996-12-20 2000-05-05 Sod Conseils Rech Applic Formes prodrogues et nouveaux analogues de la camptothecine, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
US6881555B2 (en) * 1999-03-19 2005-04-19 Aventis Pharmaceuticals Inc. AKT nucleic acids, polypeptides, and uses thereof
PL368229A1 (en) * 2001-09-25 2005-03-21 Dr.Reddy's Laboratories Limited Pharmaceutically acceptable salts of 20(s)-camptothecins
US20060084167A1 (en) * 2004-10-16 2006-04-20 Cohenford Menashi A Formation of Hybrid Cells by Fusion of Lineage Committed Cells with Stem Cells

Also Published As

Publication number Publication date
CN101495486A (zh) 2009-07-29
AU2007278500A2 (en) 2010-09-09
BRPI0714553B1 (pt) 2020-11-17
PT2044079E (pt) 2016-03-09
RU2009102243A (ru) 2010-07-27
US8217053B2 (en) 2012-07-10
PL2044079T3 (pl) 2016-06-30
AU2007278500B2 (en) 2012-06-07
KR101412157B1 (ko) 2014-06-25
CA2658900C (en) 2015-09-15
AU2007278500A1 (en) 2008-01-31
JP2009544634A (ja) 2009-12-17
SI2044079T1 (sl) 2016-02-29
ES2561356T3 (es) 2016-02-25
DK2044079T3 (en) 2016-02-29
HUE027890T2 (en) 2016-11-28
MX2009000827A (es) 2009-02-03
JP5313894B2 (ja) 2013-10-09
HK1135691A1 (en) 2010-06-11
BRPI0714553A2 (pt) 2013-03-26
WO2008011994A1 (en) 2008-01-31
BRPI0714553B8 (pt) 2021-05-25
EP2044079B1 (en) 2015-12-09
IL196653A (en) 2015-04-30
NO341812B1 (no) 2018-01-29
ITMI20061473A1 (it) 2008-01-27
CA2658900A1 (en) 2008-01-31
EP2044079A1 (en) 2009-04-08
KR20090033456A (ko) 2009-04-03
CN101495486B (zh) 2013-05-15
RU2450008C2 (ru) 2012-05-10
US20100120816A1 (en) 2010-05-13
IL196653A0 (en) 2009-11-18

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