NO20090350L - Kamptotecinderivater med antitumor-aktivitet - Google Patents

Kamptotecinderivater med antitumor-aktivitet

Info

Publication number
NO20090350L
NO20090350L NO20090350A NO20090350A NO20090350L NO 20090350 L NO20090350 L NO 20090350L NO 20090350 A NO20090350 A NO 20090350A NO 20090350 A NO20090350 A NO 20090350A NO 20090350 L NO20090350 L NO 20090350L
Authority
NO
Norway
Prior art keywords
antitumor activity
camptothecin derivatives
antitumor
derivatives
camptothecin
Prior art date
Application number
NO20090350A
Other languages
English (en)
Other versions
NO341743B1 (no
Inventor
Gabriele Fontana
Ezio Bombardelli
Cristian Samori
Arturo Battaglia
Carla Manzotti
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of NO20090350L publication Critical patent/NO20090350L/no
Publication of NO341743B1 publication Critical patent/NO341743B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Nye kamptothecin-derivater med antitumoraktivitet, fremgangsmåter for fremstilling derav, anvendelse derav som antitumormedikamenter samt farmasøytiske sammensetninger innholdende dem.
NO20090350A 2006-07-26 2009-01-23 Kamptotecinderivater med antitumor-aktivitet NO341743B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001475A ITMI20061475A1 (it) 2006-07-26 2006-07-26 Derivati della camptotecina ad attivita antitumorale
PCT/EP2007/006218 WO2008011992A1 (en) 2006-07-26 2007-07-12 Camptothecin derivatives with antitumor activity

Publications (2)

Publication Number Publication Date
NO20090350L true NO20090350L (no) 2009-01-23
NO341743B1 NO341743B1 (no) 2018-01-15

Family

ID=38520867

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090350A NO341743B1 (no) 2006-07-26 2009-01-23 Kamptotecinderivater med antitumor-aktivitet

Country Status (22)

Country Link
US (1) US8076351B2 (no)
EP (1) EP2044078B1 (no)
JP (1) JP5198447B2 (no)
KR (1) KR101398591B1 (no)
CN (1) CN101495484B (no)
AT (1) ATE482216T1 (no)
AU (1) AU2007278587B2 (no)
BR (1) BRPI0714669B8 (no)
CA (1) CA2659050C (no)
DE (1) DE602007009396D1 (no)
DK (1) DK2044078T3 (no)
ES (1) ES2350711T3 (no)
HK (1) HK1135693A1 (no)
IL (1) IL196654A (no)
IT (1) ITMI20061475A1 (no)
MX (1) MX2009000903A (no)
NO (1) NO341743B1 (no)
PL (1) PL2044078T3 (no)
PT (1) PT2044078E (no)
RU (1) RU2441009C2 (no)
SI (1) SI2044078T1 (no)
WO (1) WO2008011992A1 (no)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2972955A (en) * 1957-03-21 1961-02-28 Richter Harald Submersible pump
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
US5637770A (en) * 1991-01-16 1997-06-10 Daiichi Pharmaceutical Co., Ltd. Hexa-cyclic compound
US5834479A (en) 1993-03-05 1998-11-10 Mayer; David J. Method and composition for alleviating pain
KR960029336A (ko) * 1995-01-09 1996-08-17 김충환 캄토테신 유도체, 그의 제조 방법 및 이를 함유하는 항암제
US5972955A (en) * 1995-06-06 1999-10-26 Dr. Reddy's Research Foundation Water soluble C-ring analogues of 20(S)-camptothecin
US6177439B1 (en) 1995-06-06 2001-01-23 Reddy's Research Foundation Water soluble analogues of 20(S)-camptothecin
US6214836B1 (en) * 1995-06-06 2001-04-10 Dr. Reddy's Research Foundation Water soluble analogues of 20(S)-camptothecin
JP3600248B2 (ja) * 1996-06-05 2004-12-15 ドクター・レディーズ・ラボラトリーズ・リミテッド ２０（ｓ）−カンプトテシンの新規な水溶性ｃ−環類似体
AU4822500A (en) 1999-05-04 2000-11-17 Bionumerik Pharmaceuticals, Inc. Novel highly lipophilic camptothecin analogs

Also Published As

Publication number Publication date
RU2009102229A (ru) 2010-07-27
ITMI20061475A1 (it) 2008-01-27
AU2007278587B2 (en) 2012-11-01
EP2044078A1 (en) 2009-04-08
IL196654A0 (en) 2009-11-18
PT2044078E (pt) 2010-11-18
US20100063082A1 (en) 2010-03-11
NO341743B1 (no) 2018-01-15
US8076351B2 (en) 2011-12-13
ATE482216T1 (de) 2010-10-15
JP5198447B2 (ja) 2013-05-15
MX2009000903A (es) 2009-02-04
DE602007009396D1 (en) 2010-11-04
CA2659050A1 (en) 2008-01-31
SI2044078T1 (sl) 2011-01-31
WO2008011992A1 (en) 2008-01-31
IL196654A (en) 2015-03-31
HK1135693A1 (en) 2010-06-11
DK2044078T3 (da) 2010-12-13
BRPI0714669B8 (pt) 2021-05-25
CA2659050C (en) 2014-09-23
CN101495484A (zh) 2009-07-29
BRPI0714669A2 (pt) 2013-04-24
ES2350711T3 (es) 2011-01-26
KR101398591B1 (ko) 2014-05-27
CN101495484B (zh) 2011-12-28
RU2441009C2 (ru) 2012-01-27
PL2044078T3 (pl) 2011-03-31
WO2008011992A8 (en) 2009-02-19
JP2010500970A (ja) 2010-01-14
KR20090040304A (ko) 2009-04-23
EP2044078B1 (en) 2010-09-22
AU2007278587A1 (en) 2008-01-31
BRPI0714669B1 (pt) 2020-11-17

Similar Documents

Publication Publication Date Title
NO20090251L (no) Camptotecinderivater med antitumoraktivitet
TNSN08326A1 (en) Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
DK1951729T3 (da) Oxygenbundne pyrimidinderivater
ZA200807274B (en) Novel pyridine derivatives
TW200800968A (en) Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs
UY31673A1 (es) "derivados heterocíclicos de urea y métodos de uso de los mismos-211"
IL193772A0 (en) 4-oxoquinoline derivatives,methods for the preparation thereof and pharmaceutical compositions containing the same
MY149854A (en) Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
SG148192A1 (en) Azabenzimidazole derivatives, their manufacture and use as anti-cancer agents
WO2009071689A3 (de) 5-halogen-substituierte oxindol-derivate und ihre verwendung zur behandlung von vasopressin-abhängigen erkrankungen
HK1105419A1 (en) Camptothecin derivatives and their uses
SE0300457D0 (sv) Novel compounds
GB0615105D0 (en) Novel compounds
NO20090252L (no) Camptotecinderivater med antitumoraktivitet
CY1110787T1 (el) Νεα μορφινικα παραγωγα
GB0620619D0 (en) Novel compounds
UY30235A1 (es) Inhibidores de la adenilato ciclasa soluble
DK2044078T3 (da) Camptothecinderivater med antitumoraktivitet
NO20085267L (no) Derivater av 2-alkoksy -3,4,5-trihydroksy-alkyl amider, fremstilling og anvendelse derav, samt sammensetninger inneholdende samme
UY30236A1 (es) Inhibidores de la adenilato ciclasa soluble
DOP2007000060A (es) Inhibidores de la adenilato ciclasa soluble
MX2009009178A (es) Bis-fosforatos de bazedoxifeno.
TNSN08442A1 (en) 2-alkoxy-3,4,5-trihydroxy-alkylamide-benzothiazepines, the preparation and use thereof, and compositions containing the same

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees