HK1129111A1 - Tiotropium salts, pharmaceutical formulations containing the salts and the use thereof - Google Patents

Tiotropium salts, pharmaceutical formulations containing the salts and the use thereof

Info

Publication number
HK1129111A1
HK1129111A1 HK09108607.9A HK09108607A HK1129111A1 HK 1129111 A1 HK1129111 A1 HK 1129111A1 HK 09108607 A HK09108607 A HK 09108607A HK 1129111 A1 HK1129111 A1 HK 1129111A1
Authority
HK
Hong Kong
Prior art keywords
salts
pharmaceutical formulations
formulations containing
tiotropium
tiotropium salts
Prior art date
Application number
HK09108607.9A
Other languages
English (en)
Inventor
Rolf Banholzer
Waldemar Pfrengle
Peter Sieger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34530660&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1129111(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of HK1129111A1 publication Critical patent/HK1129111A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK09108607.9A 2003-11-03 2007-05-25 Tiotropium salts, pharmaceutical formulations containing the salts and the use thereof HK1129111A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03025075 2003-11-03

Publications (1)

Publication Number Publication Date
HK1129111A1 true HK1129111A1 (en) 2009-11-20

Family

ID=34530660

Family Applications (3)

Application Number Title Priority Date Filing Date
HK07105532.7A HK1099748A1 (en) 2003-11-03 2007-05-25 Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same
HK09108607.9A HK1129111A1 (en) 2003-11-03 2007-05-25 Tiotropium salts, pharmaceutical formulations containing the salts and the use thereof
HK11107748.7A HK1153409A1 (en) 2003-11-03 2011-07-26 Crystalline tiotropium iodide, the pharmaceutical formulation containing the same and the use thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK07105532.7A HK1099748A1 (en) 2003-11-03 2007-05-25 Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK11107748.7A HK1153409A1 (en) 2003-11-03 2011-07-26 Crystalline tiotropium iodide, the pharmaceutical formulation containing the same and the use thereof

Country Status (35)

Country Link
US (1) US8686148B2 (es)
EP (3) EP2336126A1 (es)
JP (1) JP5165244B2 (es)
KR (1) KR20060117334A (es)
CN (3) CN101407514B (es)
AR (1) AR046317A1 (es)
AT (1) ATE460414T1 (es)
AU (1) AU2004285683C1 (es)
BR (1) BRPI0416136A (es)
CA (1) CA2544348A1 (es)
CO (1) CO5690553A2 (es)
CY (2) CY1110048T1 (es)
DE (1) DE502004010885D1 (es)
DK (2) DK2067779T3 (es)
EA (1) EA012326B1 (es)
ES (2) ES2342468T3 (es)
HK (3) HK1099748A1 (es)
HR (1) HRP20100149T1 (es)
IL (1) IL175023A (es)
ME (1) ME00361B (es)
MX (1) MXPA06004697A (es)
MY (1) MY143364A (es)
NO (1) NO335814B1 (es)
NZ (1) NZ547276A (es)
PE (1) PE20050446A1 (es)
PL (2) PL1682541T3 (es)
PT (2) PT1682541E (es)
RS (2) RS20060292A (es)
SG (1) SG137859A1 (es)
SI (2) SI2067779T1 (es)
TW (2) TWI363758B (es)
UA (1) UA82413C2 (es)
UY (1) UY28590A1 (es)
WO (1) WO2005042526A1 (es)
ZA (1) ZA200602342B (es)

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CN1875020B (zh) * 2003-11-03 2010-04-28 贝林格尔.英格海姆国际有限公司 新颖的噻托铵盐,其制备方法及其药物制剂
SG137859A1 (en) 2003-11-03 2007-12-28 Boehringer Ingelheim Int Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same
US20060079544A1 (en) * 2004-08-13 2006-04-13 Boehringer Ingelheim International Gmbh Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
JP5315048B2 (ja) * 2005-06-15 2013-10-16 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規チオトロピウム塩の製造方法、新規チオトロピウム塩及びその医薬組成物
DE102005035112A1 (de) * 2005-07-27 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neues Verfahren zur Herstellung von Tiotropiumsalzen unter Anwendung von in organischen Lösungsmitteln löslichen N-Methylscopiniumsalzen
TW200738634A (en) * 2005-08-02 2007-10-16 Astrazeneca Ab New salt
PL2123650T3 (pl) 2005-12-19 2012-09-28 Sicor Inc Nowa postać bromku tiotropium i sposób jej wytwarzania
DE602006020620D1 (de) * 2006-01-04 2011-04-21 Boehringer Ingelheim Pharma Verwendung von tiotropium-salzen bei der behandlung von mässigem persistierendem asthma
EP1953156A1 (de) * 2007-01-29 2008-08-06 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung von Scopiniumsalzen
CZ201241A3 (cs) * 2012-01-20 2013-07-31 Zentiva, K.S. Nové polymorfní formy tiotropium jodidu a zpusob jejich prípravy
WO2014042605A1 (en) * 2012-09-11 2014-03-20 Mahmut Bilgic New tiotropium bromide crystalline form
JP6042197B2 (ja) * 2012-12-11 2016-12-14 エア・ウォーター株式会社 肺障害治療剤

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SG137859A1 (en) 2003-11-03 2007-12-28 Boehringer Ingelheim Int Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same
CN1875020B (zh) 2003-11-03 2010-04-28 贝林格尔.英格海姆国际有限公司 新颖的噻托铵盐,其制备方法及其药物制剂
SE0303270L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
DE102004041253A1 (de) * 2004-08-26 2006-03-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neues Verfahren zur Herstellung von Tiotropiumsalzen
JP5315048B2 (ja) * 2005-06-15 2013-10-16 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規チオトロピウム塩の製造方法、新規チオトロピウム塩及びその医薬組成物

Also Published As

Publication number Publication date
NO20061440L (no) 2006-07-12
BRPI0416136A (pt) 2007-01-02
MXPA06004697A (es) 2006-07-05
EP2067779B9 (de) 2013-10-16
EP2067779B1 (de) 2013-04-24
CN101407514A (zh) 2009-04-15
DK2067779T3 (da) 2013-07-29
MEP51308A (en) 2011-05-10
SI1682541T1 (sl) 2010-06-30
NO335814B1 (no) 2015-02-23
UA82413C2 (uk) 2008-04-10
PT1682541E (pt) 2010-04-14
EP2067779A1 (de) 2009-06-10
ATE460414T1 (de) 2010-03-15
AR046317A1 (es) 2005-11-30
TWI435876B (zh) 2014-05-01
ZA200602342B (en) 2007-06-27
CY1110048T1 (el) 2015-01-14
JP5165244B2 (ja) 2013-03-21
CN101407514B (zh) 2013-05-29
CO5690553A2 (es) 2006-10-31
ME00361B (me) 2011-10-10
AU2004285683B2 (en) 2011-04-21
HK1153409A1 (en) 2012-03-30
DK1682541T3 (da) 2010-06-28
SG137859A1 (en) 2007-12-28
DE502004010885D1 (de) 2010-04-22
EA200600886A1 (ru) 2006-10-27
CN102070630A (zh) 2011-05-25
TW200526653A (en) 2005-08-16
US8686148B2 (en) 2014-04-01
CN1882582A (zh) 2006-12-20
CN102070630B (zh) 2013-04-17
UY28590A1 (es) 2005-06-30
KR20060117334A (ko) 2006-11-16
RS51758B (en) 2011-12-31
EP1682541A1 (de) 2006-07-26
JP2007509893A (ja) 2007-04-19
MY143364A (en) 2011-04-29
CY1114157T1 (el) 2016-08-31
EA012326B1 (ru) 2009-08-28
IL175023A0 (en) 2006-08-20
CA2544348A1 (en) 2005-05-12
AU2004285683C1 (en) 2011-09-08
TWI363758B (en) 2012-05-11
ES2342468T3 (es) 2010-07-07
AU2004285683A1 (en) 2005-05-12
PL2067779T3 (pl) 2013-09-30
EP1682541B1 (de) 2010-03-10
PE20050446A1 (es) 2005-08-02
PL1682541T3 (pl) 2010-08-31
NZ547276A (en) 2009-08-28
RS20060292A (en) 2008-08-07
CN100549010C (zh) 2009-10-14
HK1099748A1 (en) 2007-08-24
ES2422729T3 (es) 2013-09-13
HRP20100149T1 (hr) 2010-04-30
IL175023A (en) 2011-02-28
TW201231465A (en) 2012-08-01
WO2005042526A1 (de) 2005-05-12
US20050131007A1 (en) 2005-06-16
SI2067779T1 (sl) 2013-08-30
PT2067779E (pt) 2013-07-25
EP2336126A1 (de) 2011-06-22

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