HK1126183A1 - Polynucleotide labelling reagent - Google Patents

Polynucleotide labelling reagent

Info

Publication number
HK1126183A1
HK1126183A1 HK09104557.8A HK09104557A HK1126183A1 HK 1126183 A1 HK1126183 A1 HK 1126183A1 HK 09104557 A HK09104557 A HK 09104557A HK 1126183 A1 HK1126183 A1 HK 1126183A1
Authority
HK
Hong Kong
Prior art keywords
nucleotide
acc
modified oligonucleotide
new
heterocycle
Prior art date
Application number
HK09104557.8A
Other languages
English (en)
Inventor
Dieter Heindl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2006/011122 external-priority patent/WO2007059912A1/fr
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1126183A1 publication Critical patent/HK1126183A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00—Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK09104557.8A 2005-11-23 2009-05-19 Polynucleotide labelling reagent HK1126183A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05025499A EP1801114B8 (fr) 2005-11-23 2005-11-23 Polynucléotides contenant des phosphates mimétiques
PCT/EP2006/008842 WO2007059816A1 (fr) 2005-11-23 2006-09-12 Polynucleotide contenant un mimetique de phosphate
PCT/EP2006/011122 WO2007059912A1 (fr) 2005-11-23 2006-11-21 Reactif de marquage de polynucleotide

Publications (1)

Publication Number Publication Date
HK1126183A1 true HK1126183A1 (en) 2009-08-28

Family

ID=36128618

Family Applications (2)

Application Number Title Priority Date Filing Date
HK09104559.6A HK1126224A1 (zh) 2005-11-23 2009-05-19 含有磷酸酯模擬物的多聚核苷酸
HK09104557.8A HK1126183A1 (en) 2005-11-23 2009-05-19 Polynucleotide labelling reagent

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK09104559.6A HK1126224A1 (zh) 2005-11-23 2009-05-19 含有磷酸酯模擬物的多聚核苷酸

Country Status (13)

Country Link
US (2) US7741472B2 (fr)
EP (3) EP1801114B8 (fr)
JP (2) JP5155177B2 (fr)
KR (2) KR101028980B1 (fr)
CN (2) CN101312985B (fr)
AT (2) ATE443072T1 (fr)
AU (1) AU2006317195B2 (fr)
BR (2) BRPI0618833B1 (fr)
CA (2) CA2627208C (fr)
DE (2) DE502005008153D1 (fr)
ES (2) ES2332139T3 (fr)
HK (2) HK1126224A1 (fr)
WO (1) WO2007059816A1 (fr)

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WO2012085064A1 (fr) 2010-12-23 2012-06-28 Roche Diagnostics Gmbh Détection d'un polypeptide à modification post-translationnelle par un agent de liaison bivalent
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ES2472965T3 (es) 2011-03-04 2014-07-03 F. Hoffmann-La Roche Ag Nuevo tipo de sondas universales para la detección de variantes gen�micas
KR101411013B1 (ko) 2011-12-01 2014-06-23 제일모직주식회사 (메타)아크릴로일 이미노포스파젠계 화합물, 그 제조방법 및 이를 포함한 공중합체
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EP2867253B1 (fr) 2012-06-27 2016-09-14 F. Hoffmann-La Roche AG Méthode de sélection et de production d'entités de ciblage personnalisées fortement sélectives et multi-spécifiques renfermant au moins deux entités de liaison différentes et leurs utilisations
JP6445429B2 (ja) 2012-06-27 2018-12-26 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 少なくとも２つの異なる標的化実体を含むテーラーメイドで選択的かつ多重特異性治療用分子を選択および作製するための方法およびその使用
CA2871882A1 (fr) 2012-06-27 2014-01-03 F. Hoffmann-La Roche Ag Methode de fabrication de conjugues d'anticorps a region fc comprenant au moins une entite de liaison qui se lie specifiquement a une cible et leurs utilisations
US9382581B2 (en) * 2012-12-13 2016-07-05 Roche Molecular Systems, Inc. Primers with modified phosphate and base in allele-specific PCR
RU2708237C2 (ru) 2014-08-22 2019-12-05 Общество с ограниченной ответственностью "НооГен" Модифицированные олигонуклеотиды и способ их получения
CN107001482B (zh) 2014-12-03 2021-06-15 豪夫迈·罗氏有限公司 多特异性抗体
JPWO2017111137A1 (ja) * 2015-12-22 2018-10-18 味の素株式会社 オリゴヌクレオチドの製造方法
RU2740501C2 (ru) * 2017-02-21 2021-01-14 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) МОДИФИЦИРОВАННЫЕ ОЛИГОНУКЛЕОТИДЫ, АКТИВИРУЮЩИЕ РНКазу Н
JP2020522510A (ja) 2017-06-02 2020-07-30 ウェイブ ライフ サイエンシズ リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． オリゴヌクレオチド組成物及びその使用方法
TW201904587A (zh) 2017-06-02 2019-02-01 新加坡商波濤生命科學有限公司 寡核苷酸組合物及其使用方法
MX2020011570A (es) 2018-05-07 2020-11-24 Alnylam Pharmaceuticals Inc Administracion extrahepatica.
US11384376B2 (en) 2018-05-31 2022-07-12 Roche Molecular Systems, Inc. Reagents and methods for post-synthetic modification of nucleic acids
JP2022544587A (ja) 2019-08-15 2022-10-19 アイオーニス ファーマシューティカルズ， インコーポレーテッド 結合修飾オリゴマー化合物及びその使用
WO2022081046A1 (fr) * 2020-10-12 2022-04-21 Максим Сергеевич КУПРЮШКИН Composé chimique avec un groupe triazine et procédé de production

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Also Published As

Publication number Publication date
JP2009516521A (ja) 2009-04-23
EP1801114B1 (fr) 2009-09-16
CA2627216C (fr) 2011-05-31
DE502005008153D1 (de) 2009-10-29
ATE443072T1 (de) 2009-10-15
US20090005550A1 (en) 2009-01-01
EP1954671B1 (fr) 2012-10-31
KR20080059323A (ko) 2008-06-26
CN101312941A (zh) 2008-11-26
HK1126224A1 (zh) 2009-08-28
US7741472B2 (en) 2010-06-22
AU2006317195B2 (en) 2010-04-01
EP1954671A1 (fr) 2008-08-13
EP1954707B1 (fr) 2010-08-18
EP1801114A1 (fr) 2007-06-27
KR101032008B1 (ko) 2011-05-02
CA2627216A1 (fr) 2007-05-31
KR20080056314A (ko) 2008-06-20
CN101312985B (zh) 2015-08-19
JP5364380B2 (ja) 2013-12-11
BRPI0618833A2 (pt) 2011-09-13
ATE478087T1 (de) 2010-09-15
CN101312941B (zh) 2012-04-18
ES2349129T3 (es) 2010-12-28
WO2007059816A1 (fr) 2007-05-31
CA2627208A1 (fr) 2007-05-31
JP5155177B2 (ja) 2013-02-27
DE602006016325D1 (de) 2010-09-30
ES2349129T8 (es) 2011-02-08
AU2006317195A1 (en) 2007-05-31
US20090012279A1 (en) 2009-01-08
BRPI0618833B1 (pt) 2015-06-16
US7795423B2 (en) 2010-09-14
EP1954707A1 (fr) 2008-08-13
JP2009516715A (ja) 2009-04-23
ES2332139T3 (es) 2010-01-27
KR101028980B1 (ko) 2011-04-12
EP1801114B8 (fr) 2009-12-02
CN101312985A (zh) 2008-11-26
BRPI0618855A2 (pt) 2011-09-13
CA2627208C (fr) 2011-11-01

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20171121