HK1113085A1 - Compounds, compositions and methods for the treatment of poxvirus infections - Google Patents

Compounds, compositions and methods for the treatment of poxvirus infections

Info

Publication number
HK1113085A1
HK1113085A1 HK08107120.0A HK08107120A HK1113085A1 HK 1113085 A1 HK1113085 A1 HK 1113085A1 HK 08107120 A HK08107120 A HK 08107120A HK 1113085 A1 HK1113085 A1 HK 1113085A1
Authority
HK
Hong Kong
Prior art keywords
compositions
compounds
treatment
methods
poxvirus infections
Prior art date
Application number
HK08107120.0A
Other languages
English (en)
Chinese (zh)
Inventor
Merrick R Almond
George R Painter
Original Assignee
Chimerix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chimerix Inc filed Critical Chimerix Inc
Publication of HK1113085A1 publication Critical patent/HK1113085A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/275—Poxviridae, e.g. avipoxvirus
    • A61K39/285—Vaccinia virus or variola virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK08107120.0A 2005-04-08 2008-06-26 Compounds, compositions and methods for the treatment of poxvirus infections HK1113085A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66973005P 2005-04-08 2005-04-08
PCT/US2006/013319 WO2006110655A2 (fr) 2005-04-08 2006-04-10 Composes, compositions et methodes de traitement des infections a poxvirus

Publications (1)

Publication Number Publication Date
HK1113085A1 true HK1113085A1 (en) 2008-09-26

Family

ID=37087597

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08107120.0A HK1113085A1 (en) 2005-04-08 2008-06-26 Compounds, compositions and methods for the treatment of poxvirus infections

Country Status (5)

Country Link
US (1) US8642577B2 (fr)
EP (1) EP1868628B1 (fr)
JP (2) JP2008535862A (fr)
HK (1) HK1113085A1 (fr)
WO (1) WO2006110655A2 (fr)

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CN105055432A (zh) 2008-01-25 2015-11-18 奇默里克斯公司 治疗病毒感染的方法
US20100082088A1 (en) * 2008-08-27 2010-04-01 Ali Fassih Treatment of sweating and hyperhydrosis
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US20120089232A1 (en) 2009-03-27 2012-04-12 Jennifer Hagyoung Kang Choi Medical devices with galvanic particulates
US8614200B2 (en) 2009-07-21 2013-12-24 Chimerix, Inc. Compounds, compositions and methods for treating ocular conditions
US20120164104A1 (en) 2009-08-03 2012-06-28 Chimerix, Inc. Composition and Methods of Treating Viral Infections and Viral Induced Tumors
JP2013509433A (ja) * 2009-10-30 2013-03-14 キメリクス，インコーポレイテッド ウイルス関連疾患を処置する方法
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US9006218B2 (en) 2010-02-12 2015-04-14 Chimerix Inc. Nucleoside phosphonate salts
US20110212042A1 (en) * 2010-03-01 2011-09-01 Prithwiraj Maitra Skin care composition having desirable bulk color
KR20160062208A (ko) 2010-03-23 2016-06-01 시가 테크놀로지스, 인크. 다형체 형태 ｓｔ―２４６ 및 제조방법
US20110236491A1 (en) * 2010-03-25 2011-09-29 Jeannette Chantalat Topical anti-inflammatory composition
CA2797601A1 (fr) 2010-04-26 2011-11-10 Chimerix, Inc. Methodes de traitement d'infections retrovirales et regimes posologiques associes
SG187243A1 (en) * 2010-08-05 2013-02-28 Siga Technologies Inc St-246 liquid formulations and methods
JP2013536865A (ja) 2010-08-31 2013-09-26 キメリクス，インコーポレイテッド ホスホン酸エステル誘導体およびその合成方法
AU2015201895B2 (en) * 2010-08-31 2016-11-17 Emergent Biodefence Operations Lansing Llc Phosphonate ester derivatives and methods of synthesis thereof
CN108210502A (zh) * 2012-07-03 2018-06-29 奇默里克斯公司 治疗逆转录病毒感染的方法和相关剂量方案
CA3090294C (fr) 2012-08-16 2023-01-24 Dongcheng Dai Procede de preparation de tecovirimat
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ES2685819T3 (es) 2013-11-15 2018-10-11 Chimerix, Inc. Formas mórficas de ésteres de hexadeciloxipropil-fosfonato
WO2016069630A1 (fr) 2014-10-27 2016-05-06 Concert Pharmaceuticals, Inc. Esters d'acide phosphonique de pyrimidine portant au moins un atome de deutérium
US20180296588A1 (en) 2017-04-14 2018-10-18 Contravir Pharmaceuticals, Inc. Combination therapy for treating viral infections
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EP1868628A4 (fr) 2009-12-02
WO2006110655A3 (fr) 2007-06-28
JP2013231058A (ja) 2013-11-14
JP2008535862A (ja) 2008-09-04
WO2006110655A2 (fr) 2006-10-19
US8642577B2 (en) 2014-02-04
US20070003516A1 (en) 2007-01-04
EP1868628B1 (fr) 2014-06-11
EP1868628A2 (fr) 2007-12-26

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