HK1091814A1 - Aminocyclohexyl ether compounds and uses thereof - Google Patents

Aminocyclohexyl ether compounds and uses thereof

Info

Publication number
HK1091814A1
HK1091814A1 HK06112250.4A HK06112250A HK1091814A1 HK 1091814 A1 HK1091814 A1 HK 1091814A1 HK 06112250 A HK06112250 A HK 06112250A HK 1091814 A1 HK1091814 A1 HK 1091814A1
Authority
HK
Hong Kong
Prior art keywords
ether compounds
aminocyclohexyl ether
compounds
compositions
present
Prior art date
Application number
HK06112250.4A
Other languages
English (en)
Inventor
Gregory N Beatch
Lewis Siu Leung Choi
Grace Jung
Liu Yuzhong
Bertrand Plouvier
Richard Wall
Jeff Zhu
Alexander Zolotoy
G M Barrett Anthony
Tao Sheng
Michael J A Walker
Sandro L Yong
Doug Ta Hung Chou
Original Assignee
Cardiome Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiome Pharma Corp filed Critical Cardiome Pharma Corp
Publication of HK1091814A1 publication Critical patent/HK1091814A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
HK06112250.4A 2003-05-02 2006-11-08 Aminocyclohexyl ether compounds and uses thereof HK1091814A1 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US46715903P 2003-05-02 2003-05-02
US47608303P 2003-06-04 2003-06-04
US47588403P 2003-06-05 2003-06-05
US47591203P 2003-06-05 2003-06-05
US47644703P 2003-06-05 2003-06-05
US48965903P 2003-07-23 2003-07-23
US49339203P 2003-08-07 2003-08-07
PCT/US2003/034655 WO2004099137A1 (fr) 2003-05-02 2003-10-31 Composes a base d'aminocyclohexyle-ether et leurs utilisations

Publications (1)

Publication Number Publication Date
HK1091814A1 true HK1091814A1 (en) 2007-01-26

Family

ID=33437310

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06112250.4A HK1091814A1 (en) 2003-05-02 2006-11-08 Aminocyclohexyl ether compounds and uses thereof

Country Status (22)

Country Link
US (3) US20070099983A1 (fr)
EP (3) EP1560812B1 (fr)
JP (2) JP4919661B2 (fr)
KR (1) KR101059379B1 (fr)
AT (2) ATE529401T1 (fr)
AU (2) AU2003287378B2 (fr)
BR (2) BR122018009866B8 (fr)
CA (1) CA2524323C (fr)
CY (1) CY1105137T1 (fr)
DE (1) DE60305200T2 (fr)
DK (1) DK1560812T3 (fr)
ES (2) ES2264776T3 (fr)
HK (1) HK1091814A1 (fr)
IL (2) IL171653A (fr)
NO (1) NO334094B1 (fr)
NZ (1) NZ543921A (fr)
PL (1) PL227937B1 (fr)
PT (1) PT1560812E (fr)
RU (1) RU2478617C2 (fr)
SG (2) SG167670A1 (fr)
SI (1) SI1560812T1 (fr)
WO (1) WO2004099137A1 (fr)

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EP1560812B1 (fr) 2003-05-02 2006-05-10 Cardiome Pharma Corp. Composes a base d'aminocyclohexyle-ether et leurs utilisations
US7345086B2 (en) 2003-05-02 2008-03-18 Cardiome Pharma Corp. Uses of ion channel modulating compounds
US7674820B2 (en) 2003-08-07 2010-03-09 Cardiome Pharma Corp. Ion channel modulating activity I
US7345087B2 (en) 2003-10-31 2008-03-18 Cardiome Pharma Corp. Aminocyclohexyl ether compounds and uses thereof
WO2005113011A2 (fr) 2004-04-01 2005-12-01 Cardiome Pharma Corp. Promedicaments de composes modulant les canaux ioniques et leurs utilisations
US8058304B2 (en) 2004-04-01 2011-11-15 Cardiome Pharma Corp. Merged ion channel modulating compounds and uses thereof
US7705036B2 (en) 2004-04-01 2010-04-27 Cardiome Pharma Corp. Deuterated aminocyclohexyl ether compounds and processes for preparing same
US7786119B2 (en) 2004-04-01 2010-08-31 Cardiome Pharma Corp. Drug conjugates of ion channel modulating compounds
CA2586918C (fr) 2004-11-08 2021-01-19 Cardiome Pharma Corp. Utilisations de composes modulant les canaux ioniques pour le traitement de la fibrillation auriculaire aigue chez l'humain
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Also Published As

Publication number Publication date
PT1560812E (pt) 2006-09-29
EP2298735A1 (fr) 2011-03-23
EP1560812B1 (fr) 2006-05-10
CA2524323C (fr) 2012-05-15
BR122018009866B8 (pt) 2021-07-27
SI1560812T1 (sl) 2006-10-31
AU2011201015A1 (en) 2011-03-31
PL378918A1 (pl) 2006-06-12
NO20055130D0 (no) 2005-11-02
JP4919661B2 (ja) 2012-04-18
ES2264776T3 (es) 2007-01-16
US8163938B2 (en) 2012-04-24
IL216579A0 (en) 2012-01-31
PL227937B1 (pl) 2018-01-31
WO2004099137A1 (fr) 2004-11-18
KR20060057531A (ko) 2006-05-26
US20070254945A1 (en) 2007-11-01
SG167670A1 (en) 2011-01-28
CY1105137T1 (el) 2010-03-03
EP1560812A1 (fr) 2005-08-10
RU2478617C2 (ru) 2013-04-10
DE60305200T2 (de) 2007-05-10
CA2524323A1 (fr) 2004-11-18
NZ543921A (en) 2008-11-28
EP1666459B1 (fr) 2011-10-19
DE60305200D1 (de) 2006-06-14
NO20055130L (no) 2005-12-01
EP1666459A2 (fr) 2006-06-07
AU2003287378B2 (en) 2010-12-16
BR122018009866B1 (pt) 2018-12-18
IL216579A (en) 2015-02-26
BR0318278A (pt) 2006-05-23
SG2010079697A (en) 2016-09-29
RU2008104198A (ru) 2009-08-10
NO334094B1 (no) 2013-12-09
BRPI0318278B1 (pt) 2018-11-06
US7767830B2 (en) 2010-08-03
EP1666459A3 (fr) 2006-09-20
ATE529401T1 (de) 2011-11-15
ES2375820T3 (es) 2012-03-06
BRPI0318278B8 (pt) 2024-01-09
US20110004006A1 (en) 2011-01-06
AU2003287378A1 (en) 2004-11-26
JP2007077162A (ja) 2007-03-29
AU2011201015B2 (en) 2012-02-02
DK1560812T3 (da) 2006-09-04
KR101059379B1 (ko) 2011-08-26
IL171653A (en) 2013-06-27
JP2006525227A (ja) 2006-11-09
US20070099983A1 (en) 2007-05-03
ATE325789T1 (de) 2006-06-15

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