HK1091731A1 - Pharmaceutical use of fused heterocyclic compounds as scce inhibitors for the treatment of skin conditions or cancer - Google Patents
Pharmaceutical use of fused heterocyclic compounds as scce inhibitors for the treatment of skin conditions or cancerInfo
- Publication number
- HK1091731A1 HK1091731A1 HK06112281.7A HK06112281A HK1091731A1 HK 1091731 A1 HK1091731 A1 HK 1091731A1 HK 06112281 A HK06112281 A HK 06112281A HK 1091731 A1 HK1091731 A1 HK 1091731A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cancer
- treatment
- heterocyclic compounds
- pharmaceutical use
- skin conditions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200300844 | 2003-06-06 | ||
DKPA200300840 | 2003-06-06 | ||
DKPA200300843 | 2003-06-06 | ||
DKPA200300842 | 2003-06-06 | ||
PCT/DK2004/000388 WO2004108139A2 (en) | 2003-06-06 | 2004-06-07 | Use of fused heterocyclic compounds as scce inhibitors for the treatment of skin conditions or cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1091731A1 true HK1091731A1 (en) | 2007-01-26 |
Family
ID=33514772
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06112281.7A HK1091731A1 (en) | 2003-06-06 | 2006-11-08 | Pharmaceutical use of fused heterocyclic compounds as scce inhibitors for the treatment of skin conditions or cancer |
HK08110652.0A HK1120209A1 (en) | 2003-06-06 | 2008-09-25 | Use of fused heterocyclic compounds as scce inhibitors |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08110652.0A HK1120209A1 (en) | 2003-06-06 | 2008-09-25 | Use of fused heterocyclic compounds as scce inhibitors |
Country Status (18)
Country | Link |
---|---|
US (1) | US7872052B2 (xx) |
EP (1) | EP1631295B1 (xx) |
JP (1) | JP5044214B2 (xx) |
KR (2) | KR101205257B1 (xx) |
CN (1) | CN101152185B (xx) |
AT (1) | ATE459359T1 (xx) |
CA (1) | CA2525383C (xx) |
CY (1) | CY1110084T1 (xx) |
DE (1) | DE602004025803D1 (xx) |
DK (1) | DK1631295T3 (xx) |
ES (1) | ES2341545T3 (xx) |
HK (2) | HK1091731A1 (xx) |
NO (1) | NO20060091L (xx) |
NZ (1) | NZ543636A (xx) |
PL (1) | PL1631295T3 (xx) |
PT (1) | PT1631295E (xx) |
SI (1) | SI1631295T1 (xx) |
WO (1) | WO2004108139A2 (xx) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10238724A1 (de) | 2002-08-23 | 2004-03-04 | Bayer Ag | Alkyl-substituierte Pyrazolpyrimidine |
DE10238722A1 (de) | 2002-08-23 | 2004-03-11 | Bayer Ag | Selektive Phosphodiesterase 9A-Inhibitoren als Arzneimittel zur Verbesserung kognitiver Prozesse |
DE10320785A1 (de) * | 2003-05-09 | 2004-11-25 | Bayer Healthcare Ag | 6-Arylmethyl-substituierte Pyrazolopyrimidine |
US8044060B2 (en) | 2003-05-09 | 2011-10-25 | Boehringer Ingelheim International Gmbh | 6-cyclylmethyl- and 6-alkylmethyl pyrazolo[3,4-D]pyrimidines, methods for their preparation and methods for their use to treat impairments of perception, concentration learning and/or memory |
DE102004001873A1 (de) | 2004-01-14 | 2005-09-29 | Bayer Healthcare Ag | Cyanopyrimidinone |
EP1909788A2 (en) * | 2005-07-29 | 2008-04-16 | Resverlogix Corp. | Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
WO2008036379A2 (en) | 2006-09-21 | 2008-03-27 | Activx Biosciences, Inc. | Serine hydrolase inhibitors |
EP2079739A2 (en) | 2006-10-04 | 2009-07-22 | Pfizer Products Inc. | Pyrido[4,3-d]pyrimidin-4(3h)-one derivatives as calcium receptor antagonists |
DK2118074T3 (en) | 2007-02-01 | 2014-03-10 | Resverlogix Corp | Compounds for the prevention and treatment of cardiovascular diseases |
AU2008290567B2 (en) | 2007-08-17 | 2011-05-12 | Novartis Ag | Cyclic depsipeptides |
JP5401459B2 (ja) * | 2007-08-17 | 2014-01-29 | ノバルティス アーゲー | カリクレイン7を阻害するための環状デプシペプチドの使用 |
EP2217602B1 (en) | 2007-11-30 | 2018-08-29 | Boehringer Ingelheim International GmbH | 1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one derivatives and their use as pde9a modulators for the treatment of cns disorders |
UA105362C2 (xx) | 2008-04-02 | 2014-05-12 | Бьорингер Ингельхайм Интернациональ Гмбх | Похідні 1-гетероцикліл-1,5-дигідропіразоло$3,4-d]піримідин-4-ону та їх застосування як модулятори pde9a$производные 1-гетероциклил-1,5-дигидропиразоло$3,4-d] пиримидин-4-она и их применение в качестве модуляторов pde9a |
EA201100446A1 (ru) | 2008-09-08 | 2011-10-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Пиразолопиримидины и их применение для лечения нарушений цнс |
JP5635535B2 (ja) | 2009-01-08 | 2014-12-03 | レスバーロジックス コーポレイション | 心血管疾患の予防および治療のための化合物 |
JP5645839B2 (ja) * | 2009-03-05 | 2014-12-24 | 武田薬品工業株式会社 | Cdc7キナーゼ阻害剤としてのチエノピリミジン |
CA2992231C (en) | 2009-03-18 | 2022-03-29 | Resverlogix Corp. | Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents |
GEP20146098B (en) | 2009-03-31 | 2014-05-27 | Boehringer Ingelheim Int | 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their usage as pde9a modulators |
KR20190091564A (ko) | 2009-04-22 | 2019-08-06 | 리스버로직스 코퍼레이션 | 신규한 소염제 |
TWI419884B (zh) * | 2010-06-24 | 2013-12-21 | Univ Chang Gung | 苯并雜氧嗪酮衍生物,其製備方法以及包含有此等衍生物的藥學組成物 |
CN103052639B (zh) | 2010-08-12 | 2016-02-17 | 贝林格尔.英格海姆国际有限公司 | 6-环烷基-1,5-二氢-吡唑并[3,4-d]嘧啶-4-酮衍生物及其作为PDE9A抑制剂的用途 |
WO2012088266A2 (en) | 2010-12-22 | 2012-06-28 | Incyte Corporation | Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3 |
US8809345B2 (en) | 2011-02-15 | 2014-08-19 | Boehringer Ingelheim International Gmbh | 6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders |
US8680054B2 (en) | 2011-04-20 | 2014-03-25 | Novartis Ag | Suspension type topical formulations comprising cyclic depsipeptide |
AR086168A1 (es) | 2011-04-20 | 2013-11-27 | Novartis Ag | Procesos para la elaboracion de depsipeptidos macrociclicos e intermediarios |
CN103945848B (zh) | 2011-11-01 | 2016-09-07 | 雷斯韦洛吉克斯公司 | 被取代的喹唑啉酮的口服即释制剂 |
RU2014141674A (ru) | 2012-03-16 | 2016-05-10 | Аксикин Фармасьютикалз, Инк. | 3,5-диаминопиразоловые ингибиторы киназы |
CN107652289B (zh) | 2012-06-13 | 2020-07-21 | 因塞特控股公司 | 作为fgfr抑制剂的取代的三环化合物 |
WO2014026125A1 (en) | 2012-08-10 | 2014-02-13 | Incyte Corporation | Pyrazine derivatives as fgfr inhibitors |
US9067978B2 (en) | 2012-10-09 | 2015-06-30 | Novartis Ag | Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates |
US8987413B2 (en) | 2012-10-09 | 2015-03-24 | Novartis Ag | Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates |
WO2014080290A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Cyclic amines as bromodomain inhibitors |
WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
US9266892B2 (en) | 2012-12-19 | 2016-02-23 | Incyte Holdings Corporation | Fused pyrazoles as FGFR inhibitors |
CA2895905A1 (en) | 2012-12-21 | 2014-06-26 | Zenith Epigenetics Corp. | Novel heterocyclic compounds as bromodomain inhibitors |
JP6449244B2 (ja) | 2013-04-19 | 2019-01-09 | インサイト・ホールディングス・コーポレイションIncyte Holdings Corporation | Fgfr抑制剤としての二環式複素環 |
NZ631142A (en) | 2013-09-18 | 2016-03-31 | Axikin Pharmaceuticals Inc | Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors |
RS61142B1 (sr) | 2014-01-23 | 2020-12-31 | Sixera Pharma Ab | Novi inhibitori kalikreina 7 |
AU2015209761B2 (en) * | 2014-01-23 | 2018-11-29 | Sixera Pharma Ab | Benzoxazinone derivatives for treatment of skin diseases |
US10851105B2 (en) | 2014-10-22 | 2020-12-01 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
KR102034202B1 (ko) | 2014-12-23 | 2019-10-18 | 에스엠에이 세라퓨틱스 아이엔씨. | 3,5-디아미노피라졸 키나제 억제제 |
US9580423B2 (en) | 2015-02-20 | 2017-02-28 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
MA41551A (fr) | 2015-02-20 | 2017-12-26 | Incyte Corp | Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4 |
WO2016134320A1 (en) | 2015-02-20 | 2016-08-25 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
KR102662814B1 (ko) | 2015-03-13 | 2024-05-03 | 리스버로직스 코퍼레이션 | 보체 관련 질환을 치료하기 위한 조성물 및 치료 방법 |
AR111960A1 (es) | 2017-05-26 | 2019-09-04 | Incyte Corp | Formas cristalinas de un inhibidor de fgfr y procesos para su preparación |
WO2019074979A1 (en) | 2017-10-09 | 2019-04-18 | Girafpharma, Llc | HETEROCYCLIC COMPOUNDS AND USES THEREOF |
AU2018347307A1 (en) * | 2017-10-09 | 2020-04-23 | Nuvation Bio Inc. | Heterocyclic compounds and uses thereof |
CN108421034A (zh) * | 2018-04-24 | 2018-08-21 | 济南磐升生物技术有限公司 | 激肽释放酶7在皮肤创伤愈合中的应用 |
DK3788047T3 (da) | 2018-05-04 | 2024-09-16 | Incyte Corp | Faste former af en FGFR-inhibitor og fremgangsmåder til fremstilling deraf |
SG11202010882XA (en) | 2018-05-04 | 2020-11-27 | Incyte Corp | Salts of an fgfr inhibitor |
US11628162B2 (en) | 2019-03-08 | 2023-04-18 | Incyte Corporation | Methods of treating cancer with an FGFR inhibitor |
MX2021012418A (es) | 2019-04-09 | 2021-11-12 | Nuvation Bio Inc | Compuestos heterociclicos y sus usos. |
WO2021007269A1 (en) | 2019-07-09 | 2021-01-14 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
US11643420B2 (en) | 2019-10-01 | 2023-05-09 | Molecular Skin Therapeutics, Inc. | Benzoxazinone compounds as KLK5/7 dual inhibitors |
MX2022004513A (es) | 2019-10-14 | 2022-07-19 | Incyte Corp | Heterociclos biciclicos como inhibidores de los receptores del factor de crecimiento de fibroblastos (fgfr). |
WO2021076728A1 (en) | 2019-10-16 | 2021-04-22 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
JP2023505258A (ja) | 2019-12-04 | 2023-02-08 | インサイト・コーポレイション | Fgfr阻害剤としての三環式複素環 |
BR112022010664A2 (pt) | 2019-12-04 | 2022-08-16 | Incyte Corp | Derivados de um inibidor de fgfr |
US12012409B2 (en) | 2020-01-15 | 2024-06-18 | Incyte Corporation | Bicyclic heterocycles as FGFR inhibitors |
JP7502945B2 (ja) | 2020-09-08 | 2024-06-19 | 花王株式会社 | デリケートエリアのかぶれの検査方法 |
EP4323405A1 (en) | 2021-04-12 | 2024-02-21 | Incyte Corporation | Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent |
WO2022253911A1 (en) | 2021-06-01 | 2022-12-08 | Sixera Pharma Ab | Oil-in-water emulsion of 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,l-benzoxazin-4-one |
CA3220274A1 (en) | 2021-06-09 | 2022-12-15 | Incyte Corporation | Tricyclic heterocycles as fgfr inhibitors |
WO2023250321A1 (en) * | 2022-06-21 | 2023-12-28 | Dana-Farber Cancer Institute, Inc. | Fused bicyclic egfr inhibitors and methods of use thereof |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1153994A (en) * | 1965-07-21 | 1969-06-04 | Aspro Nicholas Ltd | Hydroxyphenyl Anthranilic Acid Derivatives Capable of Absorbing 'Ultra-Violet Light and Compositions containing them |
FR2121341A1 (en) | 1971-01-04 | 1972-08-25 | Ferlux | 2-substd-3,1-benzoxazin-4-ones - antiinflammatories, analgesics sedatives and diuretics |
IT1050750B (it) * | 1975-12-05 | 1981-03-20 | Erba Carlo Spa | Derivati della 3.4 di idro chinazolina |
JPS5576868A (en) | 1978-12-01 | 1980-06-10 | Hisamitsu Pharmaceut Co Inc | Novel 3,1-bezoxazine derivative |
GB8817651D0 (en) * | 1988-07-25 | 1988-09-01 | Smith Kline French Lab | Chemical compounds |
EP0459983A1 (en) | 1988-12-21 | 1991-12-11 | PHARMACIA & UPJOHN COMPANY | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
JP2685648B2 (ja) * | 1990-02-15 | 1997-12-03 | 帝人株式会社 | 4h−3.1−ベンズオキサジン−4−オン化合物 |
JPH07316056A (ja) * | 1990-02-15 | 1995-12-05 | Teijin Ltd | エラスターゼ阻害用医薬組成物 |
WO1991019707A2 (en) * | 1990-06-20 | 1991-12-26 | The Upjohn Company | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
WO1992020642A1 (en) * | 1991-05-10 | 1992-11-26 | Rhone-Poulenc Rorer International (Holdings) Inc. | Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase |
US5480883A (en) * | 1991-05-10 | 1996-01-02 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
US5346886A (en) * | 1993-11-15 | 1994-09-13 | John Lezdey | Topical α-1-antitrypsin, non-aqueous lipid miscible, benzalkonium chloride compositions for treating skin |
AU1375000A (en) * | 1998-11-26 | 2000-06-13 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
JP5020451B2 (ja) * | 1999-09-10 | 2012-09-05 | ザ プロクター アンド ギャンブル カンパニー | 酵素インヒビター |
WO2002062135A2 (en) | 2001-02-09 | 2002-08-15 | Egelrud Torbjoern | Scce modified transgenic mammals and their use as models of human disease |
AU2002317377A1 (en) * | 2001-07-20 | 2003-03-03 | Cancer Research Technology Limited | Biphenyl apurinic/apyrimidinic site endonuclease inhibitors to treat cancer |
WO2004031180A1 (ja) * | 2002-10-03 | 2004-04-15 | Institute Of Medicinal Molecular Design. Inc. | キナゾリン−4−オン誘導体 |
AU2003291761A1 (en) * | 2002-11-04 | 2004-06-07 | Nps Pharmaceuticals, Inc. | Quinazolinone compounds as calcilytics |
PE20040950A1 (es) * | 2003-02-14 | 2005-01-01 | Theravance Inc | DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS |
-
2004
- 2004-06-07 CA CA2525383A patent/CA2525383C/en not_active Expired - Fee Related
- 2004-06-07 EP EP04736195A patent/EP1631295B1/en not_active Expired - Lifetime
- 2004-06-07 PT PT04736195T patent/PT1631295E/pt unknown
- 2004-06-07 DE DE602004025803T patent/DE602004025803D1/de not_active Expired - Lifetime
- 2004-06-07 NZ NZ543636A patent/NZ543636A/en not_active IP Right Cessation
- 2004-06-07 AT AT04736195T patent/ATE459359T1/de active
- 2004-06-07 PL PL04736195T patent/PL1631295T3/pl unknown
- 2004-06-07 SI SI200431406T patent/SI1631295T1/sl unknown
- 2004-06-07 WO PCT/DK2004/000388 patent/WO2004108139A2/en active Application Filing
- 2004-06-07 DK DK04736195.1T patent/DK1631295T3/da active
- 2004-06-07 CN CN2007101613027A patent/CN101152185B/zh not_active Expired - Fee Related
- 2004-06-07 KR KR1020117022051A patent/KR101205257B1/ko not_active IP Right Cessation
- 2004-06-07 JP JP2006508134A patent/JP5044214B2/ja not_active Expired - Fee Related
- 2004-06-07 ES ES04736195T patent/ES2341545T3/es not_active Expired - Lifetime
- 2004-06-07 KR KR1020057023349A patent/KR101099409B1/ko not_active IP Right Cessation
- 2004-06-07 US US10/559,322 patent/US7872052B2/en active Active
-
2006
- 2006-01-06 NO NO20060091A patent/NO20060091L/no not_active Application Discontinuation
- 2006-11-08 HK HK06112281.7A patent/HK1091731A1/xx not_active IP Right Cessation
-
2008
- 2008-09-25 HK HK08110652.0A patent/HK1120209A1/xx not_active IP Right Cessation
-
2010
- 2010-05-21 CY CY20101100450T patent/CY1110084T1/el unknown
Also Published As
Publication number | Publication date |
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CA2525383A1 (en) | 2004-12-16 |
ATE459359T1 (de) | 2010-03-15 |
DK1631295T3 (da) | 2010-06-21 |
KR20110120960A (ko) | 2011-11-04 |
CY1110084T1 (el) | 2015-01-14 |
CA2525383C (en) | 2012-03-06 |
PT1631295E (pt) | 2010-05-24 |
ES2341545T3 (es) | 2010-06-22 |
CN101152185B (zh) | 2010-12-08 |
US7872052B2 (en) | 2011-01-18 |
KR101099409B1 (ko) | 2011-12-27 |
SI1631295T1 (sl) | 2010-06-30 |
KR20060008331A (ko) | 2006-01-26 |
WO2004108139A2 (en) | 2004-12-16 |
HK1120209A1 (en) | 2009-03-27 |
KR101205257B1 (ko) | 2012-11-27 |
DE602004025803D1 (de) | 2010-04-15 |
PL1631295T3 (pl) | 2010-09-30 |
NZ543636A (en) | 2009-07-31 |
AU2004244704A1 (en) | 2004-12-16 |
EP1631295B1 (en) | 2010-03-03 |
JP2006526581A (ja) | 2006-11-24 |
CN101152185A (zh) | 2008-04-02 |
US20060258651A1 (en) | 2006-11-16 |
NO20060091L (no) | 2006-03-06 |
WO2004108139A8 (en) | 2005-04-28 |
EP1631295A2 (en) | 2006-03-08 |
WO2004108139A3 (en) | 2005-03-10 |
JP5044214B2 (ja) | 2012-10-10 |
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