HK1089438A1 - Quinoline and quinazoline derivatives having affinity for 5ht1-type receptors - Google Patents
Quinoline and quinazoline derivatives having affinity for 5ht1-type receptorsInfo
- Publication number
- HK1089438A1 HK1089438A1 HK06109772A HK06109772A HK1089438A1 HK 1089438 A1 HK1089438 A1 HK 1089438A1 HK 06109772 A HK06109772 A HK 06109772A HK 06109772 A HK06109772 A HK 06109772A HK 1089438 A1 HK1089438 A1 HK 1089438A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- quinoline
- affinity
- quinazoline derivatives
- type receptors
- receptors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Manufacturing & Machinery (AREA)
- Ceramic Engineering (AREA)
- Structural Engineering (AREA)
- Psychiatry (AREA)
- Inorganic Chemistry (AREA)
- Materials Engineering (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0316915.8A GB0316915D0 (en) | 2003-07-18 | 2003-07-18 | Compounds |
| PCT/EP2004/008000 WO2005014552A1 (fr) | 2003-07-18 | 2004-07-15 | Derives de quinoline et de quinazoline presentant une affinite vis-a-vis des recepteurs du type 5ht1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1089438A1 true HK1089438A1 (en) | 2006-12-01 |
Family
ID=27764115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK06109772A HK1089438A1 (en) | 2003-07-18 | 2006-09-01 | Quinoline and quinazoline derivatives having affinity for 5ht1-type receptors |
Country Status (29)
| Country | Link |
|---|---|
| US (5) | US7279481B2 (fr) |
| EP (3) | EP1646613B1 (fr) |
| JP (1) | JP2006528146A (fr) |
| KR (1) | KR20060041242A (fr) |
| CN (1) | CN100441571C (fr) |
| AR (1) | AR046394A1 (fr) |
| AT (2) | ATE389637T1 (fr) |
| AU (1) | AU2004263268B2 (fr) |
| BR (1) | BRPI0412695A (fr) |
| CA (1) | CA2532452A1 (fr) |
| CY (1) | CY1107974T1 (fr) |
| DE (2) | DE602004024141D1 (fr) |
| DK (1) | DK1646613T3 (fr) |
| ES (2) | ES2302543T3 (fr) |
| GB (1) | GB0316915D0 (fr) |
| HK (1) | HK1089438A1 (fr) |
| HR (1) | HRP20080226T3 (fr) |
| IL (1) | IL173036A0 (fr) |
| IS (1) | IS2744B (fr) |
| MA (1) | MA27926A1 (fr) |
| MX (1) | MXPA06000716A (fr) |
| NO (1) | NO20060774L (fr) |
| NZ (1) | NZ544586A (fr) |
| PL (1) | PL1646613T3 (fr) |
| PT (1) | PT1646613E (fr) |
| RU (1) | RU2402533C2 (fr) |
| SI (1) | SI1646613T1 (fr) |
| TW (1) | TW200521115A (fr) |
| WO (1) | WO2005014552A1 (fr) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0316915D0 (en) | 2003-07-18 | 2003-08-20 | Glaxo Group Ltd | Compounds |
| SG149027A1 (en) * | 2004-06-17 | 2009-01-29 | Cytokinetics Inc | Substituted urea derivatives for treating cardiac diseases |
| KR100817538B1 (ko) * | 2006-07-05 | 2008-03-27 | 한국화학연구원 | 신규 치환된―１ｈ―퀴나졸린―２,４―디온 유도체, 이의제조방법 및 이를 함유하는 약학적 조성물 |
| MX2009006672A (es) * | 2006-12-19 | 2009-10-26 | Univ Virginia | Efectos combinados de topiramato y ondansetron sobre el consumo de alcohol. |
| CA2677205A1 (fr) * | 2007-01-31 | 2008-08-07 | University Of Virginia Patent Foundation | Topiramate plus naltrexone pour le traitement de troubles addictifs |
| ATE499099T1 (de) | 2007-07-19 | 2011-03-15 | Esteve Labor Dr | Substituierte tetrahydro- chinolinsulfonamidverbindungen, ihre herstellung und ihre verwendung als medikamente |
| US20110065628A1 (en) * | 2007-08-27 | 2011-03-17 | University Of Virginia Patent Foundation | Medication Combinations for the Treatment of Alcoholism and Drug Addiction |
| US8697361B2 (en) | 2008-02-28 | 2014-04-15 | University Of Virginia Patent Foundation | Serotonin transporter gene and treatment of alcoholism |
| JP2011518836A (ja) | 2008-04-24 | 2011-06-30 | インサイト・コーポレイション | 大環状化合物およびそれらのキナーゼ阻害剤としての使用 |
| ES2358718T3 (es) * | 2008-05-06 | 2011-05-13 | Biedermann Motech Gmbh | Implante en forma de varilla, en concreto para la estabilización dinámica de la columna vertebral. |
| US20100298397A1 (en) * | 2009-05-19 | 2010-11-25 | Singh Nikhilesh N | Method of treatment of obsessive compulsive disorder with ondansetron |
| CN101671336B (zh) | 2009-09-23 | 2013-11-13 | 辽宁利锋科技开发有限公司 | 芳杂环并嘧啶衍生物和类似物及其制备方法和用途 |
| EP2308850A1 (fr) * | 2009-10-06 | 2011-04-13 | Laboratorios Del. Dr. Esteve, S.A. | Dérivés d'éthylamine-phényle substitué d'hétérocyclyle, leur préparation et utilisation en tant que médicaments |
| HUE035574T2 (en) | 2010-07-02 | 2018-05-28 | Univ Virginia Patent Foundation | Molecular genetic approach to treatment and diagnosis of alcohol and drug addiction |
| EP2743256B1 (fr) | 2011-08-09 | 2018-06-27 | Takeda Pharmaceutical Company Limited | Composés de cyclopropanamine |
| WO2013036721A1 (fr) | 2011-09-09 | 2013-03-14 | University Of Virginia Patent Foundation | Approche génétique moléculaire pour le traitement et le diagnostic d'une dépendance à l'alcool et d'une pharmacodépendance |
| GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| US9951088B2 (en) * | 2012-05-09 | 2018-04-24 | Sunovion Pharmaceuticals Inc. | D2 receptor modulators and methods of use thereof in the treatment of diseases and disorders |
| CN103508927A (zh) * | 2012-06-25 | 2014-01-15 | 天津药物研究院 | 一种2-甲磺酰氨基二苯醚的制备方法 |
| US9751885B2 (en) | 2012-10-12 | 2017-09-05 | Takeda Pharmaceutical Company Limited | Cyclopropanamine compound and use thereof |
| GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
| WO2015076310A1 (fr) | 2013-11-20 | 2015-05-28 | 株式会社 三和化学研究所 | Nouveau dérivé 3-azabicyclo[3.1.0]hexane et son utilisation à des fins médicales |
| US10053456B2 (en) | 2014-04-11 | 2018-08-21 | Takeda Pharmaceutical Company Limited | Cyclopropanamine compound and use thereof |
| WO2016075314A1 (fr) | 2014-11-13 | 2016-05-19 | Institut National De La Recherche Agronomique | Identification de facteurs de transcription de yarrowia lipolytica affectant la production de proteines |
| FR3028527A1 (fr) | 2014-11-13 | 2016-05-20 | Pivert | Identification de facteurs de transcription de yarrowia lipolytica |
| SI3193901T1 (en) | 2014-12-23 | 2018-06-29 | 4D Pharma Research Limited | Pirin polypeptide and immune modulation |
| ES2658310T3 (es) | 2014-12-23 | 2018-03-09 | 4D Pharma Research Limited | Una cepa de bacteroides thetaiotaomicron y su uso en la reducción de la inflamación |
| MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| MD3307288T2 (ro) | 2015-06-15 | 2019-12-31 | 4D Pharma Res Ltd | Compoziții care conțin tulpini bacteriene |
| MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| EP3650033B1 (fr) | 2015-06-15 | 2022-02-16 | 4D Pharma Research Limited | Compositions comprenant des souches bactériennes |
| HUE045754T2 (hu) | 2015-06-15 | 2020-01-28 | 4D Pharma Res Ltd | Blautia stercosis és wexlerae gyulladásos és autoimmun betegségek kezelésében történõ alkalmazásra |
| GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| TWI797067B (zh) | 2015-11-20 | 2023-04-01 | 英商4D製藥研究有限公司 | 包含細菌菌株之組合物 |
| GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
| CN114712405A (zh) | 2016-03-04 | 2022-07-08 | 4D制药有限公司 | 包含细菌菌株的组合物 |
| TW201821093A (zh) | 2016-07-13 | 2018-06-16 | 英商４Ｄ製藥有限公司 | 包含細菌菌株之組合物 |
| GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
| WO2018215758A1 (fr) | 2017-05-22 | 2018-11-29 | 4D Pharma Research Limited | Compositions comprenant des souches bactériennes |
| EP3630942B1 (fr) | 2017-05-24 | 2022-11-30 | 4D Pharma Research Limited | Compositions comprenant des souches bactériennes |
| PT3638271T (pt) | 2017-06-14 | 2021-01-05 | 4D Pharma Res Ltd | Composições contendo estirpes bacterianas |
| CA3066561C (fr) | 2017-06-14 | 2022-07-19 | 4D Pharma Research Limited | Compositions comprenant une souche bacterienne du genre megasphera et leurs utilisations |
| CN108047143A (zh) * | 2017-12-18 | 2018-05-18 | 刘凤娟 | 一种用于治疗功能性胃肠病的5-羟色胺受体拮抗剂的合成方法 |
| CN112654621B (zh) | 2018-06-27 | 2024-05-14 | 百时美施贵宝公司 | 可作为t细胞活化剂的经取代萘啶酮化合物 |
| US11866430B2 (en) | 2018-06-27 | 2024-01-09 | Bristol-Myers Squibb Company | Naphthyridinone compounds useful as T cell activators |
| AR119821A1 (es) | 2019-08-28 | 2022-01-12 | Bristol Myers Squibb Co | Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t |
| AR120823A1 (es) | 2019-12-23 | 2022-03-23 | Bristol Myers Squibb Co | Compuestos bicíclicos sustituidos útiles como activadores de células t |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2641602A (en) | 1950-11-29 | 1953-06-09 | Eastman Kodak Co | 1, 8-dihydroxy-5-nitro-4-hydroxyethylphenyl aminoanthraquinone compounds |
| US3992537A (en) * | 1971-06-07 | 1976-11-16 | Boehringer Ingelheim Gmbh | Pharmaceutical compositions containing an N-phenyl-imidazolidine-2-one and method of use |
| US3937708A (en) * | 1971-06-07 | 1976-02-10 | Boehringer Ingelheim Gmbh | N-phenyl-imidazolidine-1-ones |
| US3975525A (en) * | 1971-06-07 | 1976-08-17 | Boehringer Ingelheim Gmbh | N-[4'-Imidazolidinon-(2)-yl-phenethyl]-N'-pyridyl-piperazines and salts thereof |
| JPS5883677A (ja) | 1981-11-11 | 1983-05-19 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| US4891275A (en) * | 1982-10-29 | 1990-01-02 | Norsk Hydro A.S. | Aluminum shapes coated with brazing material and process of coating |
| JPS6354363A (ja) | 1986-08-26 | 1988-03-08 | Ss Pharmaceut Co Ltd | キノリン誘導体 |
| FI95572C (fi) | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| US4933447A (en) | 1987-09-24 | 1990-06-12 | Ss Pharmaceutical Co., Ltd. | Quinoline derivatives |
| US4891375A (en) * | 1988-01-13 | 1990-01-02 | Pfizer Inc. | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds |
| JP2777159B2 (ja) | 1988-12-22 | 1998-07-16 | エーザイ株式会社 | 環状アミン誘導体を含有する医薬 |
| GB9300195D0 (en) * | 1993-01-06 | 1993-03-03 | Wyeth John & Brother Ltd | Piperazine derivatives |
| GB9300194D0 (en) | 1993-01-06 | 1993-03-03 | Wyeth John & Brother Ltd | Piperazine derivatives |
| GB9308725D0 (en) * | 1993-04-27 | 1993-06-09 | Wyeth John & Brother Ltd | Piperazine derivatives |
| PL189256B1 (pl) * | 1996-03-29 | 2005-07-29 | Duphar Int Res | Związki piperazyny i piperydyny, sposób ich wytwarzania, kompozycja farmaceutyczna zawierająca te związki, zastosowanie tych związków do wytwarzania leków |
| WO1997041108A1 (fr) * | 1996-04-30 | 1997-11-06 | Warner-Lambert Company | Piperazines et piperidines substituees a titre d'agents actifs au niveau du systeme nerveux central |
| GB2312843A (en) | 1996-05-07 | 1997-11-12 | Merck & Co Inc | Method of treating rheumatoid arthritis |
| AU5522498A (en) | 1996-12-13 | 1998-07-03 | Merck & Co., Inc. | Substituted aryl piperazines as modulators of chemokine receptor activity |
| EP0900792B1 (fr) * | 1997-09-02 | 2003-10-29 | Duphar International Research B.V | Dérivés de pipéridine et de pipérazine comme agonistes du récepteur 5-HT1 |
| ATE253058T1 (de) * | 1997-09-02 | 2003-11-15 | Duphar Int Res | Piperidin- und piperazin derivate als 5-ht1- rezeptor-agonisten |
| DE69842058D1 (de) * | 1997-10-27 | 2011-01-27 | Neurosearch As | Heteroaryl Diazacycloalkane als cholinergische Ligande für Nikotin-Acetylcholin-Rezeptoren |
| CA2313125A1 (fr) * | 1997-12-12 | 1999-06-24 | Laramie Mary Gaster | Derives de quinoleinepiperazine et de quinoleinepiperidine, leur preparation et leur utilisation en tant qu'antagonistes combines des recepteurs 5-ht1a, 5-ht1b et 5-ht1d |
| UA62015C2 (en) * | 1998-12-28 | 2003-12-15 | Pfizer Prod Inc | Benzoizoxazol derivatives, a pharmaceutical composition (variants) based thereon (variants) and a method for treatment (variants) |
| WO2000078716A1 (fr) | 1999-06-24 | 2000-12-28 | Toray Industries, Inc. | ANTAGONISTES DU RECEPTEUR ADRENERGIQUE-α¿1B? |
| DE60017446T2 (de) * | 1999-11-05 | 2006-03-02 | Smithkline Beecham P.L.C., Brentford | Isochinolin- und Chinazolinderivate mit kombinierter 5-HT1A-, 5-HT1B- und 5-HT1D- Rezeptoraffinität |
| ATE357448T1 (de) | 2000-10-26 | 2007-04-15 | Smithkline Beecham Plc | Benzoxazinonderivative, deren herstellung und verwendung |
| CA2364211A1 (fr) * | 2000-12-05 | 2002-06-05 | Phillip Branch Chappell | Traitement combine de la depression, de l'anxiete et de la psychose |
| GB0106419D0 (en) * | 2001-03-15 | 2001-05-02 | Smithkline Beecham Plc | Novel compounds |
| MY140679A (en) | 2001-05-24 | 2010-01-15 | Avanir Pharmaceuticals | Inhibitors of macrohage migration inhibitory factor and methods for identifying the same |
| GB0203804D0 (en) | 2002-02-18 | 2002-04-03 | Glaxo Group Ltd | Compounds |
| GB0224084D0 (en) | 2002-10-16 | 2002-11-27 | Glaxo Group Ltd | Novel compounds |
| AU2003272030A1 (en) | 2002-11-08 | 2004-06-07 | Warner-Lambert Company Llc | Phenylalkyl and pyridylalkyl piperazine derivatives |
| GB0227240D0 (en) | 2002-11-21 | 2002-12-31 | Glaxo Group Ltd | Compounds |
| TW200418829A (en) | 2003-02-14 | 2004-10-01 | Avanir Pharmaceutics | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same |
| US6759435B1 (en) * | 2003-07-03 | 2004-07-06 | A.P. Group Inc. | Antidepressant drugs and methods |
| GB0316915D0 (en) | 2003-07-18 | 2003-08-20 | Glaxo Group Ltd | Compounds |
| US20050124625A1 (en) | 2003-10-21 | 2005-06-09 | Salvati Mark E. | Piperazine derivatives and their use as modulators of nuclear hormone receptor function |
| WO2005087742A1 (fr) | 2004-03-08 | 2005-09-22 | Exelixis, Inc. | Modulateurs metaboliques de kinases et leurs procedes d'utilisation en tant que pesticides |
| US20070185149A1 (en) | 2004-03-10 | 2007-08-09 | Altana Pharma Ag | Novel amido-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibtors |
| PE20060653A1 (es) | 2004-08-31 | 2006-09-27 | Glaxo Group Ltd | Derivados triciclicos condensados como moduladores del receptor 5-ht1 |
-
2003
- 2003-07-18 GB GBGB0316915.8A patent/GB0316915D0/en not_active Ceased
-
2004
- 2004-07-15 PL PL04763307T patent/PL1646613T3/pl unknown
- 2004-07-15 JP JP2006520756A patent/JP2006528146A/ja not_active Ceased
- 2004-07-15 EP EP04763307A patent/EP1646613B1/fr active Active
- 2004-07-15 DE DE602004024141T patent/DE602004024141D1/de active Active
- 2004-07-15 BR BRPI0412695-5A patent/BRPI0412695A/pt not_active IP Right Cessation
- 2004-07-15 DK DK04763307T patent/DK1646613T3/da active
- 2004-07-15 PT PT04763307T patent/PT1646613E/pt unknown
- 2004-07-15 US US10/565,066 patent/US7279481B2/en not_active Expired - Fee Related
- 2004-07-15 CA CA002532452A patent/CA2532452A1/fr not_active Abandoned
- 2004-07-15 AT AT04763307T patent/ATE389637T1/de active
- 2004-07-15 ES ES04763307T patent/ES2302543T3/es active Active
- 2004-07-15 WO PCT/EP2004/008000 patent/WO2005014552A1/fr active IP Right Grant
- 2004-07-15 AU AU2004263268A patent/AU2004263268B2/en not_active Ceased
- 2004-07-15 KR KR1020067001103A patent/KR20060041242A/ko not_active Application Discontinuation
- 2004-07-15 DE DE602004012564T patent/DE602004012564T2/de active Active
- 2004-07-15 SI SI200430699T patent/SI1646613T1/sl unknown
- 2004-07-15 CN CNB2004800270575A patent/CN100441571C/zh not_active Expired - Fee Related
- 2004-07-15 NZ NZ544586A patent/NZ544586A/en unknown
- 2004-07-15 ES ES07118193T patent/ES2336148T3/es active Active
- 2004-07-15 EP EP09175186A patent/EP2145622A1/fr not_active Withdrawn
- 2004-07-15 MX MXPA06000716A patent/MXPA06000716A/es active IP Right Grant
- 2004-07-15 AT AT07118193T patent/ATE448205T1/de not_active IP Right Cessation
- 2004-07-15 EP EP07118193A patent/EP1876174B1/fr active Active
- 2004-07-15 RU RU2006104993/04A patent/RU2402533C2/ru not_active IP Right Cessation
- 2004-07-16 AR ARP040102527A patent/AR046394A1/es not_active Application Discontinuation
- 2004-07-16 TW TW093121227A patent/TW200521115A/zh unknown
-
2006
- 2006-01-09 IL IL173036A patent/IL173036A0/en unknown
- 2006-01-18 MA MA28738A patent/MA27926A1/fr unknown
- 2006-02-15 IS IS8304A patent/IS2744B/is unknown
- 2006-02-17 NO NO20060774A patent/NO20060774L/no not_active Application Discontinuation
- 2006-09-01 HK HK06109772A patent/HK1089438A1/xx not_active IP Right Cessation
-
2007
- 2007-03-16 US US11/687,098 patent/US7459456B2/en not_active Expired - Fee Related
-
2008
- 2008-05-23 HR HR20080226T patent/HRP20080226T3/xx unknown
- 2008-05-29 CY CY20081100555T patent/CY1107974T1/el unknown
- 2008-07-02 US US12/166,547 patent/US7592346B2/en not_active Expired - Fee Related
-
2009
- 2009-08-13 US US12/540,452 patent/US7732600B2/en not_active Expired - Fee Related
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2010
- 2010-04-23 US US12/766,053 patent/US20100204273A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20120715 |