PT1646613E - Derivados de quinolina e quinazolina tendo afinidade para os receptores do tipo 5ht1 - Google Patents

Derivados de quinolina e quinazolina tendo afinidade para os receptores do tipo 5ht1 Download PDF

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Publication number
PT1646613E
PT1646613E PT04763307T PT04763307T PT1646613E PT 1646613 E PT1646613 E PT 1646613E PT 04763307 T PT04763307 T PT 04763307T PT 04763307 T PT04763307 T PT 04763307T PT 1646613 E PT1646613 E PT 1646613E
Authority
PT
Portugal
Prior art keywords
quinoline
affinity
quinazoline derivatives
type receptors
receptors
Prior art date
Application number
PT04763307T
Other languages
English (en)
Inventor
Markus Bergauer
Barbara Bertani
Matteo Biagetti
Steven Mark Bromidge
Alessandro Falchi
Colin Philip Leslie
Giancarlo Merlo
Domenica Antonia Pizzi
Marilisa Rinaldi
Luigi Piero Stasi
Jessica Tibasco
Antonio Kuok Keong Vong
Simon Edward Ward
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of PT1646613E publication Critical patent/PT1646613E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04BLIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/622Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/626Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
    • C04B35/63Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
    • C04B35/632Organic additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing & Machinery (AREA)
  • Ceramic Engineering (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Psychiatry (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
PT04763307T 2003-07-18 2004-07-15 Derivados de quinolina e quinazolina tendo afinidade para os receptores do tipo 5ht1 PT1646613E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0316915.8A GB0316915D0 (en) 2003-07-18 2003-07-18 Compounds

Publications (1)

Publication Number Publication Date
PT1646613E true PT1646613E (pt) 2008-06-19

Family

ID=27764115

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04763307T PT1646613E (pt) 2003-07-18 2004-07-15 Derivados de quinolina e quinazolina tendo afinidade para os receptores do tipo 5ht1

Country Status (29)

Country Link
US (5) US7279481B2 (pt)
EP (3) EP1646613B1 (pt)
JP (1) JP2006528146A (pt)
KR (1) KR20060041242A (pt)
CN (1) CN100441571C (pt)
AR (1) AR046394A1 (pt)
AT (2) ATE448205T1 (pt)
AU (1) AU2004263268B2 (pt)
BR (1) BRPI0412695A (pt)
CA (1) CA2532452A1 (pt)
CY (1) CY1107974T1 (pt)
DE (2) DE602004012564T2 (pt)
DK (1) DK1646613T3 (pt)
ES (2) ES2302543T3 (pt)
GB (1) GB0316915D0 (pt)
HK (1) HK1089438A1 (pt)
HR (1) HRP20080226T3 (pt)
IL (1) IL173036A0 (pt)
IS (1) IS2744B (pt)
MA (1) MA27926A1 (pt)
MX (1) MXPA06000716A (pt)
NO (1) NO20060774L (pt)
NZ (1) NZ544586A (pt)
PL (1) PL1646613T3 (pt)
PT (1) PT1646613E (pt)
RU (1) RU2402533C2 (pt)
SI (1) SI1646613T1 (pt)
TW (1) TW200521115A (pt)
WO (1) WO2005014552A1 (pt)

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Also Published As

Publication number Publication date
IS8304A (is) 2006-02-15
NO20060774L (no) 2006-04-06
ATE389637T1 (de) 2008-04-15
US7279481B2 (en) 2007-10-09
KR20060041242A (ko) 2006-05-11
JP2006528146A (ja) 2006-12-14
IS2744B (is) 2011-08-15
PL1646613T3 (pl) 2008-08-29
EP1876174A1 (en) 2008-01-09
MA27926A1 (fr) 2006-06-01
US20080280919A1 (en) 2008-11-13
US7459456B2 (en) 2008-12-02
CN100441571C (zh) 2008-12-10
SI1646613T1 (sl) 2008-08-31
US20060229312A1 (en) 2006-10-12
EP1646613A1 (en) 2006-04-19
BRPI0412695A (pt) 2006-10-03
CA2532452A1 (en) 2005-02-17
EP1876174B1 (en) 2009-11-11
US7592346B2 (en) 2009-09-22
US20090312546A1 (en) 2009-12-17
RU2006104993A (ru) 2006-08-10
WO2005014552A1 (en) 2005-02-17
RU2402533C2 (ru) 2010-10-27
MXPA06000716A (es) 2006-03-30
AU2004263268B2 (en) 2010-12-16
CY1107974T1 (el) 2013-09-04
GB0316915D0 (en) 2003-08-20
EP2145622A1 (en) 2010-01-20
HK1089438A1 (en) 2006-12-01
ATE448205T1 (de) 2009-11-15
US20070167423A1 (en) 2007-07-19
DK1646613T3 (da) 2008-07-14
US7732600B2 (en) 2010-06-08
TW200521115A (en) 2005-07-01
AR046394A1 (es) 2005-12-07
US20100204273A1 (en) 2010-08-12
DE602004024141D1 (de) 2009-12-24
ES2302543T3 (es) 2008-07-16
CN1852896A (zh) 2006-10-25
DE602004012564T2 (de) 2009-04-30
ES2336148T3 (es) 2010-04-08
IL173036A0 (en) 2006-06-11
HRP20080226T3 (en) 2008-06-30
NZ544586A (en) 2009-05-31
AU2004263268A1 (en) 2005-02-17
EP1646613B1 (en) 2008-03-19
DE602004012564D1 (de) 2008-04-30

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