HK1083227A1 - Circulating mrna as diagnostic markers for pregnancy-related disorders - Google Patents
Circulating mrna as diagnostic markers for pregnancy-related disordersInfo
- Publication number
- HK1083227A1 HK1083227A1 HK06103112A HK06103112A HK1083227A1 HK 1083227 A1 HK1083227 A1 HK 1083227A1 HK 06103112 A HK06103112 A HK 06103112A HK 06103112 A HK06103112 A HK 06103112A HK 1083227 A1 HK1083227 A1 HK 1083227A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pregnancy
- amount
- mrna species
- related disorders
- human
- Prior art date
Links
- 108020004999 messenger RNA Proteins 0.000 title abstract 3
- 230000035935 pregnancy Effects 0.000 title abstract 2
- 101000895481 Homo sapiens Corticoliberin Proteins 0.000 abstract 2
- 102000013599 Kisspeptins Human genes 0.000 abstract 2
- 108010012048 Kisspeptins Proteins 0.000 abstract 2
- 102100026181 Placenta-specific protein 1 Human genes 0.000 abstract 2
- 108050005093 Placenta-specific protein 1 Proteins 0.000 abstract 2
- 102000004576 Placental Lactogen Human genes 0.000 abstract 2
- 108010003044 Placental Lactogen Proteins 0.000 abstract 2
- 239000000381 Placental Lactogen Substances 0.000 abstract 2
- 102000006602 glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 abstract 2
- 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 abstract 2
- KAHDONZOCXSKII-NJVVDGNHSA-N kisspeptin Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H]1N(CCC1)C(=O)[C@H]1N(CCC1)C(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)O)C1=CN=CN1 KAHDONZOCXSKII-NJVVDGNHSA-N 0.000 abstract 2
- 241000894007 species Species 0.000 abstract 2
- 102000011022 Chorionic Gonadotropin Human genes 0.000 abstract 1
- 108010062540 Chorionic Gonadotropin Proteins 0.000 abstract 1
- 208000006399 Premature Obstetric Labor Diseases 0.000 abstract 1
- 208000036878 aneuploidy Diseases 0.000 abstract 1
- 231100001075 aneuploidy Toxicity 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000002759 chromosomal effect Effects 0.000 abstract 1
- 230000001605 fetal effect Effects 0.000 abstract 1
- 229940084986 human chorionic gonadotropin Drugs 0.000 abstract 1
- 230000008774 maternal effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 201000011461 pre-eclampsia Diseases 0.000 abstract 1
- 102000055046 tissue-factor-pathway inhibitor 2 Human genes 0.000 abstract 1
- 108010016054 tissue-factor-pathway inhibitor 2 Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44090603P | 2003-01-17 | 2003-01-17 | |
PCT/GB2004/000145 WO2004065629A1 (en) | 2003-01-17 | 2004-01-16 | Circulating mrna as diagnostic markers for pregnancy-related disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1083227A1 true HK1083227A1 (en) | 2006-06-30 |
Family
ID=32771876
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06103112A HK1083227A1 (en) | 2003-01-17 | 2006-03-10 | Circulating mrna as diagnostic markers for pregnancy-related disorders |
HK08113913.9A HK1122338A1 (en) | 2003-01-17 | 2008-12-23 | Circulating mrna as diagnostic markers for pregnancy-related disorders |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08113913.9A HK1122338A1 (en) | 2003-01-17 | 2008-12-23 | Circulating mrna as diagnostic markers for pregnancy-related disorders |
Country Status (9)
Country | Link |
---|---|
US (3) | US7235359B2 (xx) |
EP (1) | EP1583846B1 (xx) |
JP (1) | JP4624977B2 (xx) |
CN (3) | CN101245376A (xx) |
AT (1) | ATE533857T1 (xx) |
AU (1) | AU2004205774B2 (xx) |
CA (1) | CA2513292C (xx) |
HK (2) | HK1083227A1 (xx) |
WO (1) | WO2004065629A1 (xx) |
Families Citing this family (108)
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CN110846400A (zh) * | 2019-10-30 | 2020-02-28 | 吉林大学 | 人外周血循环FST mRNA检测试剂盒及其用途 |
CA3131748A1 (en) * | 2019-11-22 | 2021-05-27 | Sarah E. SHULTZABERGER | Circulating rna signatures specific to preeclampsia |
CN110938687B (zh) * | 2019-12-26 | 2023-06-27 | 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) | 胎盘植入性疾病标志物 |
CN110951863B (zh) * | 2019-12-26 | 2023-06-02 | 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) | 胎盘植入性疾病标志物 |
KR20220102743A (ko) * | 2021-01-14 | 2022-07-21 | 연세대학교 산학협력단 | 자간전증 또는 자간증의 예방 또는 치료용 조성물 |
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US5629147A (en) * | 1992-07-17 | 1997-05-13 | Aprogenex, Inc. | Enriching and identifying fetal cells in maternal blood for in situ hybridization |
US5750339A (en) * | 1994-11-30 | 1998-05-12 | Thomas Jefferson University | Methods for identifying fetal cells |
FR2745638A1 (fr) * | 1996-03-04 | 1997-09-05 | Roussy Inst Gustave | Procede pour la detection de la transformation maligne de cellules humaines |
AU5794498A (en) * | 1996-12-10 | 1998-07-03 | Genetrace Systems, Inc. | Releasable nonvolatile mass-label molecules |
GB9704444D0 (en) * | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
AU2001273318A1 (en) * | 2000-07-07 | 2002-01-21 | Genetics Institute, Llc | Methods and compositions for diagnosing and treating preeclampsia and gestational trophoblast disorders |
US6664056B2 (en) * | 2000-10-17 | 2003-12-16 | The Chinese University Of Hong Kong | Non-invasive prenatal monitoring |
NZ529254A (en) | 2001-06-19 | 2006-01-27 | Idaho Res Foundation | Determination of pregnancy status in an ungulate animal |
EP1428835B1 (en) * | 2001-09-19 | 2007-04-18 | Takeda Pharmaceutical Company Limited | Antibody against metastin and use of the same in the diagnosis of pregnancy |
US20040009518A1 (en) | 2002-05-14 | 2004-01-15 | The Chinese University Of Hong Kong | Methods for evaluating a disease condition by nucleic acid detection and fractionation |
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AU2004205774B2 (en) | 2006-12-14 |
US20040203037A1 (en) | 2004-10-14 |
JP4624977B2 (ja) | 2011-02-02 |
CN1723289A (zh) | 2006-01-18 |
US20080153090A1 (en) | 2008-06-26 |
US20090162842A1 (en) | 2009-06-25 |
HK1122338A1 (en) | 2009-05-15 |
CA2513292A1 (en) | 2004-08-05 |
AU2004205774A1 (en) | 2004-08-05 |
JP2006515517A (ja) | 2006-06-01 |
CA2513292C (en) | 2016-04-05 |
CN101245376A (zh) | 2008-08-20 |
EP1583846B1 (en) | 2011-11-16 |
CN101260429A (zh) | 2008-09-10 |
CN101260429B (zh) | 2011-03-30 |
CN100379882C (zh) | 2008-04-09 |
WO2004065629A1 (en) | 2004-08-05 |
US7235359B2 (en) | 2007-06-26 |
US7829285B2 (en) | 2010-11-09 |
ATE533857T1 (de) | 2011-12-15 |
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