HK1077578B - 用於制备5-(2'-吡啶基)-2-吡啶酮衍生物的方法 - Google Patents

用於制备5-(2'-吡啶基)-2-吡啶酮衍生物的方法 Download PDF

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Publication number
HK1077578B
HK1077578B HK05112103.4A HK05112103A HK1077578B HK 1077578 B HK1077578 B HK 1077578B HK 05112103 A HK05112103 A HK 05112103A HK 1077578 B HK1077578 B HK 1077578B
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HK
Hong Kong
Prior art keywords
formula
derivative
atom
agent
pyridyl
Prior art date
Application number
HK05112103.4A
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English (en)
Chinese (zh)
Other versions
HK1077578A1 (en
Inventor
小役丸健一
福永佳美
佐竹庸一
Original Assignee
可乐丽股份有限公司
卫材R&D管理有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 可乐丽股份有限公司, 卫材R&D管理有限公司 filed Critical 可乐丽股份有限公司
Publication of HK1077578A1 publication Critical patent/HK1077578A1/xx
Publication of HK1077578B publication Critical patent/HK1077578B/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK05112103.4A 2002-07-23 2003-07-23 用於制备5-(2'-吡啶基)-2-吡啶酮衍生物的方法 HK1077578B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002214098A JP4208512B2 (ja) 2002-07-23 2002-07-23 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法
JP2002-214098 2002-07-23
PCT/JP2003/009316 WO2004009553A1 (ja) 2002-07-23 2003-07-23 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法

Publications (2)

Publication Number Publication Date
HK1077578A1 HK1077578A1 (en) 2006-02-17
HK1077578B true HK1077578B (zh) 2009-03-27

Family

ID=30767870

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05112103.4A HK1077578B (zh) 2002-07-23 2003-07-23 用於制备5-(2'-吡啶基)-2-吡啶酮衍生物的方法

Country Status (13)

Country Link
US (1) US7524967B2 (enExample)
EP (1) EP1553086B1 (enExample)
JP (1) JP4208512B2 (enExample)
KR (1) KR101025528B1 (enExample)
CN (1) CN100393702C (enExample)
AT (1) ATE444952T1 (enExample)
AU (1) AU2003252241B2 (enExample)
CA (1) CA2493036C (enExample)
DE (1) DE60329615D1 (enExample)
HK (1) HK1077578B (enExample)
IL (1) IL166451A (enExample)
MX (1) MXPA05000944A (enExample)
WO (1) WO2004009553A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY148809A (en) 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
JP5180816B2 (ja) * 2005-04-04 2013-04-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 神経変性疾患および認知症のためのジヒドロピリジン化合物
JP5112317B2 (ja) 2005-08-29 2013-01-09 バーテックス ファーマシューティカルズ インコーポレイテッド 非受容体型チロシンキナーゼのtecファミリーの阻害剤として有用な3,5−二置換ピリド−2−オン
WO2007027729A1 (en) 2005-08-29 2007-03-08 Vertex Pharmaceuticals Incorporated 3, 5-disubstituted pyrid-2-ones useful as inhibitors of tec family of non-receptor tyrosine kinases
AU2006285038A1 (en) * 2005-08-29 2007-03-08 Vertex Pharmaceuticals Incorporated 3,5-disubstituted pyrid-2-ones useful as inhibitors of Tec family of non-receptor tyrosine kinases
JP4865337B2 (ja) * 2006-01-24 2012-02-01 富士フイルムファインケミカルズ株式会社 2,3’−ビピリジル−6’−オンの製造方法
US20100016603A1 (en) * 2007-01-29 2010-01-21 Fujifilm Finechemicals Co., Ltd. Production process of 2,3'-bipyridyl-6'-one
US20100099714A1 (en) * 2007-03-05 2010-04-22 Eisai R&D Management Co., Ltd. AMPA and NMDA Receptor Antagonists for Neurodegenerative Diseases
WO2008139984A1 (en) * 2007-04-26 2008-11-20 Eisai R & D Management Co., Ltd. Cinnamide compounds for dementia
WO2009081872A1 (ja) * 2007-12-21 2009-07-02 Kuraray Co., Ltd. 6-ハロゲノ-3-アリールピリジン誘導体の製造方法
ITMI20111952A1 (it) 2011-10-27 2013-04-28 Italiana Sint Spa Procedimento per la prepazione di 2-metossi-5-(piridin-2-il)piridina, un intermedio del perampanel
US9096574B2 (en) 2012-01-03 2015-08-04 Mapi Pharma Ltd. Polymorphs of perampanel
EA031384B1 (ru) 2013-07-25 2018-12-28 Тева Фармасьютикалз Интернэшнл Гмбх Улучшенные способы получения перампанеля
CN104725301A (zh) * 2013-12-20 2015-06-24 北京蓝贝望生物医药科技股份有限公司 一种1,2-二氢吡啶-2-酮衍生物的制备方法
US10111867B2 (en) 2015-02-17 2018-10-30 Mapi Pharma Ltd. Process and intermediates for the preparation of perampanel
AU2019317366A1 (en) 2018-08-06 2021-03-04 Olive Seed Industries, Llc Methods and systems for personalizing visitor experience at a venue
US20240247019A1 (en) * 2021-05-24 2024-07-25 Sumitomo Chemical Company, Limited Method for producing bipyridine derivative, method for producing macrocyclic compound, method for producing metal complex containing macrocyclic compound as ligand, metal complex, electrode for air battery, and air battery
CN116930351A (zh) * 2023-06-08 2023-10-24 上海现代制药股份有限公司 一种hplc测定吡仑帕奈关键起始物料有关物质的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693611A (en) 1996-02-01 1997-12-02 Eli Lilly And Company Cyclic peptide antifungal agents
DE19633746A1 (de) 1996-08-22 1998-02-26 Basf Ag Substituierte 2-Phenylpyridine
DE19636995A1 (de) * 1996-09-12 1998-03-19 Basf Ag Verfahren zur Herstellung substituierter Phenylpyridine
JP4176201B2 (ja) 1998-09-02 2008-11-05 株式会社クラレ 5−ハロゲノ−2−置換ピリジンの製造方法
HK1049834A1 (zh) 1999-10-11 2003-05-30 辉瑞大药厂 用作磷酸二酯酶抑制剂的5-(2-取代的-5-杂环基磺酰基吡啶-3-基)-二氢吡唑并[4,3-d]嘧啶-7-酮类化合物
US20020045613A1 (en) 2000-04-27 2002-04-18 Heinz Pauls 1-aroyl-piperidinyl benzamidines
WO2001096308A1 (en) 2000-06-12 2001-12-20 Eisai Co., Ltd. 1,2-dihydropyridine compounds, process for preparation of the same and use thereof

Also Published As

Publication number Publication date
KR101025528B1 (ko) 2011-04-04
HK1077578A1 (en) 2006-02-17
JP2004051592A (ja) 2004-02-19
WO2004009553A1 (ja) 2004-01-29
ATE444952T1 (de) 2009-10-15
EP1553086A1 (en) 2005-07-13
US20060004205A1 (en) 2006-01-05
CN100393702C (zh) 2008-06-11
US7524967B2 (en) 2009-04-28
JP4208512B2 (ja) 2009-01-14
CA2493036C (en) 2011-03-22
AU2003252241A1 (en) 2004-02-09
IL166451A0 (en) 2006-01-15
CA2493036A1 (en) 2004-01-29
IL166451A (en) 2011-07-31
DE60329615D1 (de) 2009-11-19
MXPA05000944A (es) 2005-10-18
CN1671665A (zh) 2005-09-21
KR20050019919A (ko) 2005-03-03
EP1553086B1 (en) 2009-10-07
AU2003252241B2 (en) 2008-12-04
EP1553086A4 (en) 2007-04-25

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Free format text: CORRECTION OF THE TITLE OF INVENTION FROM PROCESS FOR PRODUCING 5- (2"-PYRIDYL)-2-PYRIDONE DERIVATIVE TO PROCESS FOR PRODUCING 5-(2 - PYRIDYL)-2-PYRIDONE DERIVATIVE

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150723