HK1077578B - 用於制备5-(2'-吡啶基)-2-吡啶酮衍生物的方法 - Google Patents

用於制备5-(2'-吡啶基)-2-吡啶酮衍生物的方法 Download PDF

Info

Publication number
HK1077578B
HK1077578B HK05112103.4A HK05112103A HK1077578B HK 1077578 B HK1077578 B HK 1077578B HK 05112103 A HK05112103 A HK 05112103A HK 1077578 B HK1077578 B HK 1077578B
Authority
HK
Hong Kong
Prior art keywords
formula
derivative
atom
agent
pyridyl
Prior art date
Application number
HK05112103.4A
Other languages
English (en)
Chinese (zh)
Other versions
HK1077578A1 (en
Inventor
小役丸健一
福永佳美
佐竹庸一
Original Assignee
可乐丽股份有限公司
卫材R&D管理有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 可乐丽股份有限公司, 卫材R&D管理有限公司 filed Critical 可乐丽股份有限公司
Publication of HK1077578A1 publication Critical patent/HK1077578A1/xx
Publication of HK1077578B publication Critical patent/HK1077578B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK05112103.4A 2002-07-23 2003-07-23 用於制备5-(2'-吡啶基)-2-吡啶酮衍生物的方法 HK1077578B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002214098A JP4208512B2 (ja) 2002-07-23 2002-07-23 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法
JP2002-214098 2002-07-23
PCT/JP2003/009316 WO2004009553A1 (ja) 2002-07-23 2003-07-23 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法

Publications (2)

Publication Number Publication Date
HK1077578A1 HK1077578A1 (en) 2006-02-17
HK1077578B true HK1077578B (zh) 2009-03-27

Family

ID=30767870

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05112103.4A HK1077578B (zh) 2002-07-23 2003-07-23 用於制备5-(2'-吡啶基)-2-吡啶酮衍生物的方法

Country Status (13)

Country Link
US (1) US7524967B2 (enExample)
EP (1) EP1553086B1 (enExample)
JP (1) JP4208512B2 (enExample)
KR (1) KR101025528B1 (enExample)
CN (1) CN100393702C (enExample)
AT (1) ATE444952T1 (enExample)
AU (1) AU2003252241B2 (enExample)
CA (1) CA2493036C (enExample)
DE (1) DE60329615D1 (enExample)
HK (1) HK1077578B (enExample)
IL (1) IL166451A (enExample)
MX (1) MXPA05000944A (enExample)
WO (1) WO2004009553A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY148809A (en) 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
ME01224B (me) * 2005-04-04 2013-06-20 Eisai R&D Man Co Ltd Jedinjenja dihidropiridina za liječenje neurodegenerativnih bolesti i demencije
AU2006285145A1 (en) 2005-08-29 2007-03-08 Vertex Pharmaceuticals Incorporated 3,5-disubstituted pyrid-2-ones useful as inhibitors of Tec family of non-.receptor tyrosine kinases
WO2007027594A1 (en) * 2005-08-29 2007-03-08 Vertex Pharmaceuticals Incorporated 3,5-disubstituted pyrid-2-ones useful as inhibitors of tec family of non-receptor tyrosine kinases
ATE528302T1 (de) 2005-08-29 2011-10-15 Vertex Pharma 3,5-disubstituierte pyrid-2-one, die als hemmer der tec-familie von nicht-rezeptor tyrosin- kinasen nützlich sind
JP4865337B2 (ja) * 2006-01-24 2012-02-01 富士フイルムファインケミカルズ株式会社 2,3’−ビピリジル−6’−オンの製造方法
US20100016603A1 (en) * 2007-01-29 2010-01-21 Fujifilm Finechemicals Co., Ltd. Production process of 2,3'-bipyridyl-6'-one
JP2010520154A (ja) * 2007-03-05 2010-06-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 神経変性疾患のためのampaレセプターアンタゴニストおよびnmdaレセプターアンタゴニスト
WO2008139984A1 (en) * 2007-04-26 2008-11-20 Eisai R & D Management Co., Ltd. Cinnamide compounds for dementia
US8742127B2 (en) 2007-12-21 2014-06-03 Kuraray Co., Ltd. Production method of 6-halogeno-3-arylpyridine derivative
ITMI20111952A1 (it) 2011-10-27 2013-04-28 Italiana Sint Spa Procedimento per la prepazione di 2-metossi-5-(piridin-2-il)piridina, un intermedio del perampanel
EP2800747A4 (en) 2012-01-03 2015-12-09 Mapi Pharma Ltd POLYMORPHY OF PERAMPANEL
EP3024821B1 (en) 2013-07-25 2017-09-27 Teva Pharmaceuticals International GmbH Process for the preparation of perampanel
CN104725301A (zh) * 2013-12-20 2015-06-24 北京蓝贝望生物医药科技股份有限公司 一种1,2-二氢吡啶-2-酮衍生物的制备方法
US10111867B2 (en) 2015-02-17 2018-10-30 Mapi Pharma Ltd. Process and intermediates for the preparation of perampanel
CA3109115A1 (en) 2018-08-06 2020-02-13 Olive Seed Industries, Llc Methods and systems for personalizing visitor experience at a venue
CN116930351A (zh) * 2023-06-08 2023-10-24 上海现代制药股份有限公司 一种hplc测定吡仑帕奈关键起始物料有关物质的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693611A (en) 1996-02-01 1997-12-02 Eli Lilly And Company Cyclic peptide antifungal agents
DE19633746A1 (de) 1996-08-22 1998-02-26 Basf Ag Substituierte 2-Phenylpyridine
DE19636995A1 (de) 1996-09-12 1998-03-19 Basf Ag Verfahren zur Herstellung substituierter Phenylpyridine
JP4176201B2 (ja) 1998-09-02 2008-11-05 株式会社クラレ 5−ハロゲノ−2−置換ピリジンの製造方法
JP2003511452A (ja) 1999-10-11 2003-03-25 ファイザー・インク ホスホジエステラーゼ阻害剤としての5−(2−置換−5−ヘテロシクリルスルホニルピリド−3−イル)−ジヒドロピラゾロ[4,3−d]ピリミジン−7−オン
US20020045613A1 (en) 2000-04-27 2002-04-18 Heinz Pauls 1-aroyl-piperidinyl benzamidines
CN1245386C (zh) * 2000-06-12 2006-03-15 卫材株式会社 1,2-二氢吡啶化合物及其制备方法和用途

Also Published As

Publication number Publication date
MXPA05000944A (es) 2005-10-18
ATE444952T1 (de) 2009-10-15
IL166451A (en) 2011-07-31
CN100393702C (zh) 2008-06-11
CA2493036C (en) 2011-03-22
EP1553086A1 (en) 2005-07-13
US20060004205A1 (en) 2006-01-05
AU2003252241B2 (en) 2008-12-04
US7524967B2 (en) 2009-04-28
EP1553086B1 (en) 2009-10-07
WO2004009553A1 (ja) 2004-01-29
JP4208512B2 (ja) 2009-01-14
EP1553086A4 (en) 2007-04-25
DE60329615D1 (de) 2009-11-19
HK1077578A1 (en) 2006-02-17
KR101025528B1 (ko) 2011-04-04
CN1671665A (zh) 2005-09-21
IL166451A0 (en) 2006-01-15
JP2004051592A (ja) 2004-02-19
AU2003252241A1 (en) 2004-02-09
KR20050019919A (ko) 2005-03-03
CA2493036A1 (en) 2004-01-29

Similar Documents

Publication Publication Date Title
HK1077578B (zh) 用於制备5-(2'-吡啶基)-2-吡啶酮衍生物的方法
KR100423627B1 (ko) 캄프토테신유도체(씨피티-11)및관련화합물의제조를위한신규중간체및제조방법
US10329311B1 (en) Process for the preparation of crisaborole
EP0551459B1 (en) Method for the preparation of 3-amino-2-chloro-4-alkylpyridines
CN113135869A (zh) 一种制备α-芳基羰基化合物的方法及产品
HK1077579A (en) Process for producing 5-(2'-pyridyl)-2-pyridone derivative
US5677458A (en) Method of preparing azatetralones
JP4119114B2 (ja) 新規なジヒドロキシ(3−ピリジル)ボラン類
JP2583062B2 (ja) 複素環化合物の製造法
JPS6343389B2 (enExample)
JPH0421674A (ja) 2―クロロ―5―(アミノメチル)チアゾールの製造方法
JPH0586940B2 (enExample)
Picci et al. 3, 5-dichloro-4-pyridinecarbonitrile: a multisite substrate for carbon nucleophiles
JP2000080082A (ja) 5−ハロゲノ−2−置換ピリジンの製造方法
WO2000076976A1 (en) Process for the production of 2-pyridylpyridine derivatives
JPH0959254A (ja) 2−ヒドロキシピリジン類および/または2(1h)−ピリドン類の製造法
JP4675234B2 (ja) 光学活性なキノロンカルボン酸誘導体の製造中間体およびその製造法
US20070105857A1 (en) Process for Making Heteroaryl Amine Intermediate Compounds
JP3272170B2 (ja) ピリジン誘導体の製造法
US5744608A (en) Method for manufacturing 3-(aminomethyl)-6-chloropyridines
JP4287083B2 (ja) 2−または4−モノ置換ピリジンの製造方法並びに4−モノ置換ピリジンまたはその塩の選択的製造方法および分離方法
JPH0959253A (ja) 2−アラルキルオキシピリジン類の製造法
JP3569877B2 (ja) m−置換−α−ヒドロキシメチルスチレン誘導体の製造法および3−クロロ−α−ブロモスチレン
JPH01313462A (ja) 2‐ヒドロキシピリジンの製造方法
JP2003321468A (ja) ピリドン化合物の製造法およびその中間体

Legal Events

Date Code Title Description
CHRG Changes in the register

Free format text: CORRECTION OF THE TITLE OF INVENTION FROM PROCESS FOR PRODUCING 5- (2"-PYRIDYL)-2-PYRIDONE DERIVATIVE TO PROCESS FOR PRODUCING 5-(2 - PYRIDYL)-2-PYRIDONE DERIVATIVE

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150723