HK1074458A1 - Thermostable taq polymerase fragment - Google Patents

Thermostable taq polymerase fragment

Info

Publication number
HK1074458A1
HK1074458A1 HK05105938.9A HK05105938A HK1074458A1 HK 1074458 A1 HK1074458 A1 HK 1074458A1 HK 05105938 A HK05105938 A HK 05105938A HK 1074458 A1 HK1074458 A1 HK 1074458A1
Authority
HK
Hong Kong
Prior art keywords
delta
taq
taqwt
nucleic acid
well
Prior art date
Application number
HK05105938.9A
Other languages
English (en)
Inventor
Waltraud Ankenbauer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1074458A1 publication Critical patent/HK1074458A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
HK05105938.9A 2003-08-12 2005-07-12 Thermostable taq polymerase fragment HK1074458A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03017636 2003-08-12

Publications (1)

Publication Number Publication Date
HK1074458A1 true HK1074458A1 (en) 2005-11-11

Family

ID=34130067

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05105938.9A HK1074458A1 (en) 2003-08-12 2005-07-12 Thermostable taq polymerase fragment

Country Status (15)

Country Link
US (1) US7972830B2 (de)
EP (1) EP1507002B1 (de)
JP (1) JP3929061B2 (de)
KR (1) KR100626578B1 (de)
CN (1) CN1590543B (de)
AT (1) ATE348881T1 (de)
AU (1) AU2004203649B2 (de)
BR (1) BRPI0403221A (de)
CA (1) CA2474734C (de)
DE (1) DE602004003755T2 (de)
DK (1) DK1507002T3 (de)
ES (1) ES2278249T3 (de)
HK (1) HK1074458A1 (de)
MX (1) MXPA04007721A (de)
SG (1) SG109552A1 (de)

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DE102006025154A1 (de) * 2006-05-30 2007-12-06 Universität Konstanz Mutierte DNA-Polymerase mit erhöhter Reverse Transkriptase Aktivität
EP2113574A1 (de) 2008-04-28 2009-11-04 Biotype AG Stoffe und Verfahren für Profilierungstest auf DNA-Basis
EP2644707B1 (de) 2008-04-30 2015-06-03 Integrated Dna Technologies, Inc. RNase-H basierte Assays unter Verwendung von RNA Monomeren
US20140255925A9 (en) * 2008-04-30 2014-09-11 Integrated Dna Technologies Modified rnase h enzymes and their uses
JP5809059B2 (ja) 2008-11-03 2015-11-10 カパ バイオシステムズ， インコーポレイテッド 改変ａ型ｄｎａポリメラーゼ
IN2012DN05145A (de) 2009-11-19 2015-10-23 Solis Biodyne
US20110250598A1 (en) 2010-04-12 2011-10-13 Ulrike Fischer Detergent free polymerases
US9315787B2 (en) 2011-01-14 2016-04-19 Kapa Biosystems, Inc. Modified DNA polymerases for improved amplification
WO2012135053A2 (en) 2011-03-25 2012-10-04 Integrated Dna Technologies, Inc. Rnase h-based assays utilizing modified rna monomers
WO2012146260A1 (de) 2011-04-23 2012-11-01 Biolytix Ag Herstellung und verwendung von proteinen in der molekularbiologie
US9567628B2 (en) 2011-06-08 2017-02-14 Life Technologies Corporation Polymerization of nucleic acids using proteins having low isoelectric points
ES2692894T3 (es) 2011-06-08 2018-12-05 Life Technologies Corporation Diseño y desarrollo de nuevos detergentes para su uso en sistemas de PCR
EP3063129B1 (de) 2013-10-25 2019-04-17 Life Technologies Corporation Neuartige verbindungen zur verwendung in pcr-systemen und anwendungen davon
CN107208074B (zh) * 2014-12-16 2021-06-15 生命技术公司 聚合酶组合物和制造与使用其的方法
ES2759477T3 (es) 2015-05-29 2020-05-11 Hoffmann La Roche Un procedimiento de inactivación de microbios por anhídrido citracónico
WO2017090684A1 (ja) * 2015-11-27 2017-06-01 国立大学法人九州大学 Ｄｎａポリメラーゼ変異体
GB201604876D0 (en) * 2016-03-22 2016-05-04 Uni I Tromsø Norges Arktiske Uni Marine DNA polymerases
CN108265039B (zh) * 2016-12-30 2020-07-14 天津强微特生物科技有限公司 一种突变TaqDNA聚合酶及其纯化方法
WO2018183612A1 (en) * 2017-03-29 2018-10-04 Editas Medicine, Inc. Nucleic acid mutagenesis methods
US11299776B2 (en) * 2017-05-10 2022-04-12 Board Of Regents, The University Of Texas System Methods and devices related to amplifying nucleic acid at a variety of temperatures
CN111684064A (zh) 2018-01-19 2020-09-18 生物辐射实验室股份有限公司 突变dna聚合酶
GB201812428D0 (en) * 2018-07-31 2018-09-12 Bg Res Ltd Improved method for pathogen detection
BR112022021086A2 (pt) 2020-04-30 2022-12-13 Stab Vida Investig E Servicos Em Ciencias Biologicas Lda Sistema integrado para a detecção e identificação de sequências específicas de ácidos nucleicos e método de utilização do sistema integrado
US11649441B2 (en) * 2020-10-07 2023-05-16 Abclonal Science, Inc. Taq DNA polymerase mutants for probe qPCR
WO2023122291A2 (en) * 2021-12-23 2023-06-29 Sherlock Biosciences, Inc. Methods for polypeptide purification
CN116024320A (zh) * 2022-07-13 2023-04-28 上海翔琼生物技术有限公司 一种用于检测核酸的荧光定量pcr方法

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CA2409775C (en) 2001-12-03 2010-07-13 F. Hoffmann-La Roche Ag Reversibly modified thermostable enzymes for dna synthesis and amplification in vitro

Also Published As

Publication number Publication date
KR20050025266A (ko) 2005-03-14
MXPA04007721A (es) 2005-07-12
US20050037412A1 (en) 2005-02-17
CN1590543B (zh) 2010-05-12
ES2278249T3 (es) 2007-08-01
DK1507002T3 (da) 2007-04-10
CA2474734C (en) 2010-07-13
AU2004203649B2 (en) 2006-01-12
CA2474734A1 (en) 2005-02-12
CN1590543A (zh) 2005-03-09
DE602004003755T2 (de) 2007-10-11
SG109552A1 (en) 2005-03-30
JP3929061B2 (ja) 2007-06-13
JP2005058236A (ja) 2005-03-10
EP1507002A2 (de) 2005-02-16
EP1507002A3 (de) 2005-07-27
KR100626578B1 (ko) 2006-09-25
US7972830B2 (en) 2011-07-05
EP1507002B1 (de) 2006-12-20
ATE348881T1 (de) 2007-01-15
DE602004003755D1 (de) 2007-02-01
AU2004203649A1 (en) 2005-03-03
BRPI0403221A (pt) 2005-07-12

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190812