HK1071572A1 - PyrazoloÄ1,5-AÜpyrimidine compounds as cyclin dependent kinase inhibitors - Google Patents

PyrazoloÄ1,5-AÜpyrimidine compounds as cyclin dependent kinase inhibitors

Info

Publication number
HK1071572A1
HK1071572A1 HK05104747A HK05104747A HK1071572A1 HK 1071572 A1 HK1071572 A1 HK 1071572A1 HK 05104747 A HK05104747 A HK 05104747A HK 05104747 A HK05104747 A HK 05104747A HK 1071572 A1 HK1071572 A1 HK 1071572A1
Authority
HK
Hong Kong
Prior art keywords
aüpyrimidine
compounds
kinase inhibitors
dependent kinase
cyclin dependent
Prior art date
Application number
HK05104747A
Other languages
English (en)
Inventor
Timothy J Guzi
Kamil Paruch
Ronald J Doll
Michael P Dwyer
Carmen S Alvarez
Tin-Yau Chan
Vincent Madison
Thierry O Fischmann
Lawrence W Dillard
Vinh D Tran
Zhen Min He
Ray Anthony James
Haengsoon Park
Viyyoor Moopil Girijavallabhan
Chad Knutson
Original Assignee
Schering Corp
Pharmacopeia Drug Discovery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp, Pharmacopeia Drug Discovery filed Critical Schering Corp
Publication of HK1071572A1 publication Critical patent/HK1071572A1/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
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    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • A61P7/06—Antianaemics
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Psychology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
HK05104747A 2002-09-04 2005-06-07 PyrazoloÄ1,5-AÜpyrimidine compounds as cyclin dependent kinase inhibitors HK1071572A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40802902P 2002-09-04 2002-09-04
PCT/US2003/027491 WO2004026229A2 (en) 2002-09-04 2003-09-03 Pyrazolo[1,5-a]pyrimidines compounds as cyclin dependent kinase inhibitors

Publications (1)

Publication Number Publication Date
HK1071572A1 true HK1071572A1 (en) 2005-07-22

Family

ID=32030632

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05104747A HK1071572A1 (en) 2002-09-04 2005-06-07 PyrazoloÄ1,5-AÜpyrimidine compounds as cyclin dependent kinase inhibitors

Country Status (19)

Country Link
US (2) US7067661B2 (de)
EP (1) EP1534712B1 (de)
JP (2) JP4790265B2 (de)
KR (1) KR20050033659A (de)
CN (1) CN1701073B (de)
AR (1) AR041133A1 (de)
AT (1) ATE362474T1 (de)
AU (1) AU2003298571B2 (de)
CA (1) CA2497544C (de)
DE (1) DE60313872T2 (de)
ES (1) ES2283868T3 (de)
HK (1) HK1071572A1 (de)
MX (1) MXPA05002572A (de)
MY (2) MY145332A (de)
NZ (1) NZ539161A (de)
PE (1) PE20041000A1 (de)
TW (1) TWI329645B (de)
WO (1) WO2004026229A2 (de)
ZA (1) ZA200501846B (de)

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AR041133A1 (es) 2005-05-04
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