HK1062305A1 - Concatameric immunoadhesion - Google Patents
Concatameric immunoadhesionInfo
- Publication number
- HK1062305A1 HK1062305A1 HK04103532A HK04103532A HK1062305A1 HK 1062305 A1 HK1062305 A1 HK 1062305A1 HK 04103532 A HK04103532 A HK 04103532A HK 04103532 A HK04103532 A HK 04103532A HK 1062305 A1 HK1062305 A1 HK 1062305A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- proteins
- soluble
- dimeric
- terminus
- host cells
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 abstract 8
- 108090000623 proteins and genes Proteins 0.000 abstract 8
- 239000013613 expression plasmid Substances 0.000 abstract 2
- 238000003259 recombinant expression Methods 0.000 abstract 2
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 102000018071 Immunoglobulin Fc Fragments Human genes 0.000 abstract 1
- 108010091135 Immunoglobulin Fc Fragments Proteins 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 102000035122 glycosylated proteins Human genes 0.000 abstract 1
- 108091005608 glycosylated proteins Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70507—CD2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2001-0045028A KR100453877B1 (ko) | 2001-07-26 | 2001-07-26 | 연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 TNFR/Fc 융합 단백질, 상기 단백질을 코딩하는 DNA, 상기 DNA를 포함하는벡터, 및 상기 벡터에 의한 형질전환체 |
PCT/KR2002/001427 WO2003010202A1 (en) | 2001-07-26 | 2002-07-26 | Concatameric immunoadhesion |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1062305A1 true HK1062305A1 (en) | 2004-10-29 |
Family
ID=36638258
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK04103532A HK1062305A1 (en) | 2001-07-26 | 2004-05-19 | Concatameric immunoadhesion |
Country Status (12)
Country | Link |
---|---|
US (3) | US7229962B2 (xx) |
EP (1) | EP1362062B1 (xx) |
JP (1) | JP4288159B2 (xx) |
KR (1) | KR100453877B1 (xx) |
CN (1) | CN1293098C (xx) |
AT (1) | ATE294817T1 (xx) |
AU (1) | AU2002313952B2 (xx) |
CA (1) | CA2429384C (xx) |
DE (1) | DE60203996T2 (xx) |
ES (1) | ES2239242T3 (xx) |
HK (1) | HK1062305A1 (xx) |
WO (1) | WO2003010202A1 (xx) |
Families Citing this family (95)
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2001
- 2001-07-26 KR KR10-2001-0045028A patent/KR100453877B1/ko active IP Right Grant
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- 2002-07-26 JP JP2003515561A patent/JP4288159B2/ja not_active Expired - Lifetime
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- 2002-07-26 DE DE60203996T patent/DE60203996T2/de not_active Expired - Lifetime
- 2002-07-26 AT AT02753273T patent/ATE294817T1/de active
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Also Published As
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WO2003010202A1 (en) | 2003-02-06 |
EP1362062B1 (en) | 2005-05-04 |
CA2429384C (en) | 2012-08-07 |
EP1362062A4 (en) | 2004-04-14 |
JP4288159B2 (ja) | 2009-07-01 |
US20090011466A1 (en) | 2009-01-08 |
DE60203996T2 (de) | 2006-01-19 |
KR20030010189A (ko) | 2003-02-05 |
AU2002313952B2 (en) | 2003-11-27 |
ATE294817T1 (de) | 2005-05-15 |
CN1524092A (zh) | 2004-08-25 |
EP1362062A1 (en) | 2003-11-19 |
KR100453877B1 (ko) | 2004-10-20 |
US20030195338A1 (en) | 2003-10-16 |
US20100278827A1 (en) | 2010-11-04 |
DE60203996D1 (de) | 2005-06-09 |
US8372961B2 (en) | 2013-02-12 |
US7229962B2 (en) | 2007-06-12 |
CN1293098C (zh) | 2007-01-03 |
JP2004521655A (ja) | 2004-07-22 |
US7670602B2 (en) | 2010-03-02 |
ES2239242T3 (es) | 2005-09-16 |
CA2429384A1 (en) | 2003-02-06 |
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