DE60203996D1 - Concatamere immunadhäsion - Google Patents

Concatamere immunadhäsion

Info

Publication number
DE60203996D1
DE60203996D1 DE60203996T DE60203996T DE60203996D1 DE 60203996 D1 DE60203996 D1 DE 60203996D1 DE 60203996 T DE60203996 T DE 60203996T DE 60203996 T DE60203996 T DE 60203996T DE 60203996 D1 DE60203996 D1 DE 60203996D1
Authority
DE
Germany
Prior art keywords
proteins
soluble
dimeric
terminus
host cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60203996T
Other languages
English (en)
Other versions
DE60203996T2 (de
Inventor
Yong-Hoon Chung
Ji-Woong Han
Hye-Ja Lee
Eun-Yong Choi
Jin-Mi Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medexgen Inc
Original Assignee
Medexgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medexgen Inc filed Critical Medexgen Inc
Application granted granted Critical
Publication of DE60203996D1 publication Critical patent/DE60203996D1/de
Publication of DE60203996T2 publication Critical patent/DE60203996T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70507—CD2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
DE60203996T 2001-07-26 2002-07-26 Concatamere immunadhäsion Expired - Lifetime DE60203996T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2001-0045028A KR100453877B1 (ko) 2001-07-26 2001-07-26 연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
KR2001045028 2001-07-26
PCT/KR2002/001427 WO2003010202A1 (en) 2001-07-26 2002-07-26 Concatameric immunoadhesion

Publications (2)

Publication Number Publication Date
DE60203996D1 true DE60203996D1 (de) 2005-06-09
DE60203996T2 DE60203996T2 (de) 2006-01-19

Family

ID=36638258

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60203996T Expired - Lifetime DE60203996T2 (de) 2001-07-26 2002-07-26 Concatamere immunadhäsion

Country Status (12)

Country Link
US (3) US7229962B2 (de)
EP (1) EP1362062B1 (de)
JP (1) JP4288159B2 (de)
KR (1) KR100453877B1 (de)
CN (1) CN1293098C (de)
AT (1) ATE294817T1 (de)
AU (1) AU2002313952B2 (de)
CA (1) CA2429384C (de)
DE (1) DE60203996T2 (de)
ES (1) ES2239242T3 (de)
HK (1) HK1062305A1 (de)
WO (1) WO2003010202A1 (de)

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US20100278827A1 (en) 2010-11-04
KR20030010189A (ko) 2003-02-05
ES2239242T3 (es) 2005-09-16
EP1362062A4 (de) 2004-04-14
AU2002313952B2 (en) 2003-11-27
US20030195338A1 (en) 2003-10-16
KR100453877B1 (ko) 2004-10-20
JP4288159B2 (ja) 2009-07-01
US20090011466A1 (en) 2009-01-08
HK1062305A1 (en) 2004-10-29
DE60203996T2 (de) 2006-01-19
CN1524092A (zh) 2004-08-25
US7229962B2 (en) 2007-06-12
US8372961B2 (en) 2013-02-12
ATE294817T1 (de) 2005-05-15
EP1362062A1 (de) 2003-11-19
CA2429384A1 (en) 2003-02-06
CA2429384C (en) 2012-08-07
WO2003010202A1 (en) 2003-02-06
CN1293098C (zh) 2007-01-03

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