HK1060357A1 - Beta-lactam compounds, process for reproducing thesame and serum cholesterol-lowering agents contai ning the same - Google Patents

Beta-lactam compounds, process for reproducing thesame and serum cholesterol-lowering agents contai ning the same

Info

Publication number
HK1060357A1
HK1060357A1 HK04103348A HK04103348A HK1060357A1 HK 1060357 A1 HK1060357 A1 HK 1060357A1 HK 04103348 A HK04103348 A HK 04103348A HK 04103348 A HK04103348 A HK 04103348A HK 1060357 A1 HK1060357 A1 HK 1060357A1
Authority
HK
Hong Kong
Prior art keywords
group
carbon atoms
chain
thesame
reproducing
Prior art date
Application number
HK04103348A
Other languages
English (en)
Inventor
Hiroshi Tomiyama
Masayuki Yokota
Atsushi Noda
Akira Ohno
Original Assignee
Kotobuki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kotobuki Pharmaceutical Co Ltd filed Critical Kotobuki Pharmaceutical Co Ltd
Publication of HK1060357A1 publication Critical patent/HK1060357A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
HK04103348A 2001-02-23 2004-05-12 Beta-lactam compounds, process for reproducing thesame and serum cholesterol-lowering agents contai ning the same HK1060357A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001048202 2001-02-23
JP2001128031 2001-04-25
PCT/JP2002/001481 WO2002066464A1 (en) 2001-02-23 2002-02-20 β-LACTAM COMPOUNDS, PROCESS FOR REPODUCING THE SAME AND SERUM CHOLESTEROL-LOWERING AGENTS CONTAINING THE SAME

Publications (1)

Publication Number Publication Date
HK1060357A1 true HK1060357A1 (en) 2004-08-06

Family

ID=26609978

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04103348A HK1060357A1 (en) 2001-02-23 2004-05-12 Beta-lactam compounds, process for reproducing thesame and serum cholesterol-lowering agents contai ning the same

Country Status (18)

Country Link
US (1) US7045515B2 (ja)
EP (1) EP1362855B1 (ja)
JP (1) JP4229701B2 (ja)
KR (1) KR100721639B1 (ja)
CN (1) CN1273467C (ja)
AT (1) ATE374769T1 (ja)
AU (1) AU2002237522B2 (ja)
BR (1) BRPI0206193B1 (ja)
CA (1) CA2438961C (ja)
DE (1) DE60222742T2 (ja)
DK (1) DK1362855T3 (ja)
ES (1) ES2294101T3 (ja)
HK (1) HK1060357A1 (ja)
MX (1) MXPA03005073A (ja)
PT (1) PT1362855E (ja)
RU (1) RU2301799C2 (ja)
TW (1) TWI291957B (ja)
WO (1) WO2002066464A1 (ja)

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AR059021A1 (es) * 2006-01-18 2008-03-05 Schering Corp Moduladores de receptores cannabinoides
JP4880348B2 (ja) * 2006-04-25 2012-02-22 壽製薬株式会社 アズレン誘導体及びそれを有効成分とする血清コレステロール低下剤
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EP2061767B1 (de) 2006-08-08 2014-12-17 Sanofi Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung
CN101583612A (zh) * 2006-09-15 2009-11-18 先灵公司 治疗脂质代谢障碍的氮杂环丁酮衍生物
US7638526B2 (en) * 2006-09-15 2009-12-29 Schering Corporation Azetidine derivatives useful in treating pain, diabetes and disorders of lipid metabolism
KR20090071589A (ko) 2006-09-15 2009-07-01 쉐링 코포레이션 통증 및 지질 대사 장애의 치료에 유용한 아제티딘 및 아제티돈 유도체
MX2009002924A (es) * 2006-09-15 2009-05-28 Schering Corp Derivados de azetidinona espirociclica para el tratamiento de trastornos del metabolismo de los lipidos, el dolor, la diabetes y otros trastornos.
US20100035857A1 (en) * 2006-12-20 2010-02-11 Devita Robert J Anti-hypercholesterolemic compounds
DE102007005045B4 (de) 2007-01-26 2008-12-18 Sanofi-Aventis Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2008130616A2 (en) * 2007-04-19 2008-10-30 Schering Corporation Diaryl morpholines as cb1 modulators
MX2010000334A (es) * 2007-06-28 2010-04-22 Intervet Int Bv Piperazinas sustituidas como antagonistas de cannabinoides 1.
WO2009005671A2 (en) * 2007-06-28 2009-01-08 Schering Corporation Substituted piperazines as cb1 antagonists
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102007054497B3 (de) 2007-11-13 2009-07-23 Sanofi-Aventis Deutschland Gmbh Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
US8470841B2 (en) 2008-07-09 2013-06-25 Sanofi Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
US20110245209A1 (en) 2008-12-16 2011-10-06 Schering Corporation Pyridopyrimidine derivatives and methods of use thereof
US20110243940A1 (en) 2008-12-16 2011-10-06 Schering Corporation Bicyclic pyranone derivatives and methods of use thereof
WO2010100255A1 (en) 2009-03-06 2010-09-10 Lipideon Biotechnology Ag Pharmaceutical hypocholesterolemic compositions
CN101993403B (zh) 2009-08-11 2012-07-11 浙江海正药业股份有限公司 氮杂环丁酮类化合物及医药应用
RU2012111354A (ru) 2009-08-26 2013-10-10 Санофи Новые кристаллические гидраты фторгликозидов, содержащие их фармацевтические препараты и их использование
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683700B1 (de) 2011-03-08 2015-02-18 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8710050B2 (en) 2011-03-08 2014-04-29 Sanofi Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683698B1 (de) 2011-03-08 2017-10-04 Sanofi Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683702B1 (de) 2011-03-08 2014-12-24 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683703B1 (de) 2011-03-08 2015-05-27 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120053A1 (de) 2011-03-08 2012-09-13 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8846666B2 (en) 2011-03-08 2014-09-30 Sanofi Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
CN104860980B (zh) * 2015-04-23 2018-06-19 上海弈柯莱生物医药科技有限公司 一种用于合成依折麦布的中间体及其制备方法和应用
EP3942048A1 (en) 2019-03-20 2022-01-26 Regeneron Pharmaceuticals, Inc. Treatment of increased lipid levels with sterol regulatory element binding transcription factor 1 (srebf1) inhibitors
CA3133002A1 (en) 2019-03-20 2020-09-24 Regeneron Pharmaceuticals, Inc. Treatment of increased lipid levels with sterol regulatory element binding protein cleavage-activating protein (scap) inhibitors

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Also Published As

Publication number Publication date
DK1362855T3 (da) 2008-01-28
MXPA03005073A (es) 2003-09-05
DE60222742D1 (de) 2007-11-15
BR0206193A (pt) 2004-02-03
RU2301799C2 (ru) 2007-06-27
CN1273467C (zh) 2006-09-06
CA2438961C (en) 2010-02-16
KR20030076690A (ko) 2003-09-26
AU2002237522B2 (en) 2007-08-02
TWI291957B (en) 2008-01-01
ATE374769T1 (de) 2007-10-15
JPWO2002066464A1 (ja) 2004-06-17
WO2002066464A1 (en) 2002-08-29
ES2294101T3 (es) 2008-04-01
RU2003128424A (ru) 2005-01-27
US7045515B2 (en) 2006-05-16
BRPI0206193B1 (pt) 2016-05-24
CA2438961A1 (en) 2002-08-29
PT1362855E (pt) 2007-12-04
JP4229701B2 (ja) 2009-02-25
KR100721639B1 (ko) 2007-05-23
EP1362855B1 (en) 2007-10-03
CN1492865A (zh) 2004-04-28
DE60222742T2 (de) 2008-07-17
EP1362855A4 (en) 2005-02-23
EP1362855A1 (en) 2003-11-19
US20040063929A1 (en) 2004-04-01

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20170220