HK1050473B - 含有白喉和破傷風毒素的無細胞百日咳疫苗 - Google Patents

含有白喉和破傷風毒素的無細胞百日咳疫苗

Info

Publication number
HK1050473B
HK1050473B HK03101055.7A HK03101055A HK1050473B HK 1050473 B HK1050473 B HK 1050473B HK 03101055 A HK03101055 A HK 03101055A HK 1050473 B HK1050473 B HK 1050473B
Authority
HK
Hong Kong
Prior art keywords
toxoids
diphtheriae
tetanus
pertussis vaccine
acellular pertussis
Prior art date
Application number
HK03101055.7A
Other languages
English (en)
Other versions
HK1050473A1 (en
Inventor
Florent Patrick
Stephenne Jean
Vandecasserie Christian
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of HK1050473A1 publication Critical patent/HK1050473A1/xx
Publication of HK1050473B publication Critical patent/HK1050473B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/08Clostridium, e.g. Clostridium tetani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0016Combination vaccines based on diphtheria-tetanus-pertussis
    • A61K39/0018Combination vaccines based on acellular diphtheria-tetanus-pertussis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/05Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K2039/10Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
HK03101055.7A 1996-11-07 2000-03-10 含有白喉和破傷風毒素的無細胞百日咳疫苗 HK1050473B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9623233.5A GB9623233D0 (en) 1996-11-07 1996-11-07 Vaccine composition
HK00101495A HK1022638A1 (en) 1996-11-07 2000-03-10 Acellular pertussis vaccine with diphthriae-and tetanustoxoids

Publications (2)

Publication Number Publication Date
HK1050473A1 HK1050473A1 (en) 2003-06-27
HK1050473B true HK1050473B (zh) 2006-03-03

Family

ID=10802615

Family Applications (2)

Application Number Title Priority Date Filing Date
HK00101495A HK1022638A1 (en) 1996-11-07 2000-03-10 Acellular pertussis vaccine with diphthriae-and tetanustoxoids
HK03101055.7A HK1050473B (zh) 1996-11-07 2000-03-10 含有白喉和破傷風毒素的無細胞百日咳疫苗

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK00101495A HK1022638A1 (en) 1996-11-07 2000-03-10 Acellular pertussis vaccine with diphthriae-and tetanustoxoids

Country Status (30)

Country Link
EP (2) EP1240905B3 (zh)
JP (1) JP3980652B2 (zh)
KR (1) KR100518044B1 (zh)
CN (1) CN1130226C (zh)
AR (1) AR011509A1 (zh)
AT (2) ATE222773T1 (zh)
AU (1) AU710475B2 (zh)
BR (2) BRPI9712917B8 (zh)
CA (1) CA2271008C (zh)
CO (1) CO4910171A1 (zh)
CY (2) CY2407B1 (zh)
CZ (1) CZ295954B6 (zh)
DE (3) DE69715031T2 (zh)
DK (2) DK0941117T3 (zh)
ES (2) ES2182131T3 (zh)
GB (1) GB9623233D0 (zh)
HK (2) HK1022638A1 (zh)
HU (1) HU224126B1 (zh)
IL (1) IL129530A (zh)
LU (1) LU91183I2 (zh)
NO (2) NO320186B1 (zh)
NZ (1) NZ335384A (zh)
PL (1) PL188460B1 (zh)
PT (2) PT941117E (zh)
SA (1) SA98181128B1 (zh)
SI (2) SI0941117T1 (zh)
TR (1) TR199900979T2 (zh)
TW (1) TW471971B (zh)
WO (1) WO1998019702A1 (zh)
ZA (1) ZA979984B (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1004314A1 (fr) * 1998-11-26 2000-05-31 Pasteur Merieux MSD Vaccin T.d. Polio rappel pour une population vaccinée ou sensibilisée
KR100374813B1 (ko) * 2000-04-07 2003-03-03 녹십자백신 주식회사 디프테리아, 파상풍 톡소이드, 정제백일해 및비형간염표면항원을 포함한 4가 혼합백신 및 그 제조 방법
GB0108364D0 (en) * 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
KR100401423B1 (ko) * 2001-01-10 2003-10-17 주식회사 엘지생명과학 혼합 백신의 제조 방법
JP5007425B2 (ja) * 2006-01-30 2012-08-22 財団法人ヒューマンサイエンス振興財団 百日咳ワクチンの安全性評価方法
GB0616306D0 (en) * 2006-08-16 2006-09-27 Novartis Ag Vaccines
GB0822633D0 (en) * 2008-12-11 2009-01-21 Novartis Ag Formulation
CN102844047B (zh) 2009-09-02 2017-04-05 诺华股份有限公司 含tlr活性调节剂的免疫原性组合物
US20120177681A1 (en) 2010-09-01 2012-07-12 Manmohan Singh Formulation of immunopotentiators
CA2828844C (en) 2011-03-02 2020-07-14 Novartis Ag Combination vaccines with lower doses of antigen and/or adjuvant
CN102363041A (zh) * 2011-11-17 2012-02-29 成都欧林生物科技股份有限公司 不含防腐剂疫苗的制作工艺
WO2013132041A2 (en) 2012-03-08 2013-09-12 Novartis Ag Adjuvanted formulations of booster vaccines
CN102793915B (zh) * 2012-07-25 2013-10-23 天津康希诺生物技术有限公司 一种无细胞百日咳疫苗的生产方法
CA2879939A1 (en) 2012-08-06 2014-02-13 Glaxosmithkline Biologicals S.A. Novel method
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
CN103100081A (zh) * 2012-12-26 2013-05-15 天津康希诺生物技术有限公司 一种多价联合疫苗
ES2597832T3 (es) 2013-03-08 2017-01-23 Janssen Vaccines & Prevention B.V. Vacuna acelular contra la tosferina
CA2919773A1 (en) 2013-08-05 2015-02-12 Glaxosmithkline Biologicals S.A. Combination immunogenic compositions
CN114748616A (zh) * 2022-05-23 2022-07-15 中国医学科学院医学生物学研究所 一种成人青少年用无细胞百白破联合疫苗及其制备方法
CN117417419B (zh) * 2023-01-10 2024-04-19 康希诺生物股份公司 一种百日咳毒素脱毒方法及无细胞百白破联合疫苗

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI861417A0 (fi) 1985-04-15 1986-04-01 Endotronics Inc Hepatitis b ytantigen framstaelld med rekombinant-dna-teknik, vaccin, diagnostiskt medel och cellinjer samt foerfaranden foer framstaellning daerav.
US4895800A (en) 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
ZA88488B (en) 1987-01-30 1988-10-26 Smith Kline Rit Hepatitis b virus surface antigens and hybrid antigens containing them
EP0304578B1 (en) 1987-06-22 2001-10-24 Medeva Holdings Bv Peptide comprising hepatitis B surface antigen
DE3789866T2 (de) 1987-07-17 1994-09-22 Rhein Biotech Proz & Prod Gmbh DNA-Moleküle, die für FMDH-Kontrollabschnitte und Strukturgene für ein Protein mit FMDH-Aktivität kodieren, sowie deren Anwendung.
SG48175A1 (en) 1989-07-25 1998-04-17 Smithkline Beecham Biolog Novel antigens and method for their preparation
GB9007024D0 (en) 1990-03-29 1990-05-30 Imperial College Novel vaccine
HU220236B (hu) 1992-05-23 2001-11-28 Smithkline Beecham Biologicals S.A. Hepatitis B felszíni antigént és egyéb antigéneket tartalmazó, kombinált oltóanyagok

Also Published As

Publication number Publication date
EP1240905B3 (en) 2009-08-26
EP1240905B1 (en) 2005-05-11
HK1022638A1 (en) 2000-08-18
ES2182131T3 (es) 2003-03-01
ATE222773T1 (de) 2002-09-15
HU224126B1 (hu) 2005-05-30
PL333127A1 (en) 1999-11-22
DE69733285T3 (de) 2010-03-25
TR199900979T2 (xx) 1999-07-21
NO992156L (no) 1999-05-04
DE69715031D1 (de) 2002-10-02
DK1240905T5 (da) 2010-01-11
NO2006005I1 (no) 2006-05-08
CY2407B1 (en) 2004-09-10
ES2240647T7 (es) 2010-03-31
DE69715031T2 (de) 2003-05-08
BR9712917A (pt) 1999-12-07
PL188460B1 (pl) 2005-02-28
IL129530A (en) 2005-11-20
JP3980652B2 (ja) 2007-09-26
CN1130226C (zh) 2003-12-10
BRPI9712917B1 (pt) 2019-12-03
NO2006005I2 (no) 2010-04-12
NO320186B1 (no) 2005-11-07
AR011509A1 (es) 2000-08-30
NO992156D0 (no) 1999-05-04
JP2001503422A (ja) 2001-03-13
DE69733285T2 (de) 2006-01-12
ZA979984B (en) 1998-07-23
HUP9904287A3 (en) 2001-05-28
CN1236321A (zh) 1999-11-24
ATE295178T1 (de) 2005-05-15
CA2271008C (en) 2008-07-22
DE69733285D1 (de) 2005-06-16
CZ164099A3 (cs) 1999-10-13
DE122005000046I1 (de) 2005-12-29
TW471971B (en) 2002-01-11
CZ295954B6 (cs) 2005-12-14
DK1240905T3 (da) 2005-07-18
WO1998019702A1 (en) 1998-05-14
AU710475B2 (en) 1999-09-23
ES2240647T3 (es) 2005-10-16
SI1240905T1 (en) 2005-10-31
KR100518044B1 (ko) 2005-09-30
AU5319698A (en) 1998-05-29
BRPI9712917B8 (pt) 2021-05-25
SA98181128B1 (ar) 2006-03-25
DK0941117T3 (da) 2002-11-18
EP1240905A1 (en) 2002-09-18
SI0941117T1 (en) 2002-12-31
CO4910171A1 (es) 2000-04-24
PT941117E (pt) 2002-12-31
HUP9904287A1 (hu) 2000-04-28
NZ335384A (en) 2000-10-27
PT1240905E (pt) 2005-09-30
GB9623233D0 (en) 1997-01-08
LU91183I2 (fr) 2005-09-20
EP0941117A1 (en) 1999-09-15
CA2271008A1 (en) 1998-05-14
HK1050473A1 (en) 2003-06-27
CY2568B1 (en) 2008-07-02
EP0941117B1 (en) 2002-08-28
KR20000053092A (ko) 2000-08-25
IL129530A0 (en) 2000-02-29

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20161104