BR9712917A - Vacina pertussis acelular com toxóides diftérico e tetânico - Google Patents

Vacina pertussis acelular com toxóides diftérico e tetânico

Info

Publication number
BR9712917A
BR9712917A BR9712917-8A BR9712917A BR9712917A BR 9712917 A BR9712917 A BR 9712917A BR 9712917 A BR9712917 A BR 9712917A BR 9712917 A BR9712917 A BR 9712917A
Authority
BR
Brazil
Prior art keywords
diphtheria
pertussis
vaccine
pertussis vaccine
acellular pertussis
Prior art date
Application number
BR9712917-8A
Other languages
English (en)
Inventor
Patrick Florent
Jean Stephenne
Cristian Vandecasserie
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Publication of BR9712917A publication Critical patent/BR9712917A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
    • A61K39/0018—Combination vaccines based on acellular diphtheria-tetanus-pertussis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Patente de Invenção:<B>"VACINA PERTUSSIS ACELULAR COM TOXóIDES DIFTéRICO E TETâNICO"<D>. A invenção fornece uma vacina contra difteria, tétano e pertussis compreendendo uma baixa dose de cada dos toxóide diftérico (D), toxóide tetânico (T), toxina pertussis (PT), hemaglutinina filamentosa (FHA) e pertactin (69K). A vacina mantém uma capacidade de prevenir pertussis ao mesmo tempo que apresentando reatogenicidade excepcionalmente baixa. Também são fornecidas combinações de vacinas compreendendo antígenos adicionais.
BR9712917-8A 1996-11-07 1997-11-04 Vacina pertussis acelular com toxóides diftérico e tetânico BR9712917A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9623233.5A GB9623233D0 (en) 1996-11-07 1996-11-07 Vaccine composition
PCT/EP1997/006180 WO1998019702A1 (en) 1996-11-07 1997-11-04 Acellular pertussis vaccine with diphthriae- and tetanus-toxoids

Publications (1)

Publication Number Publication Date
BR9712917A true BR9712917A (pt) 1999-12-07

Family

ID=10802615

Family Applications (2)

Application Number Title Priority Date Filing Date
BR9712917-8A BR9712917A (pt) 1996-11-07 1997-11-04 Vacina pertussis acelular com toxóides diftérico e tetânico
BRPI9712917A BRPI9712917B8 (pt) 1996-11-07 1997-11-04 composição de vacina compreendendo toxóides diftérico, tetânico e pertussis.

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI9712917A BRPI9712917B8 (pt) 1996-11-07 1997-11-04 composição de vacina compreendendo toxóides diftérico, tetânico e pertussis.

Country Status (30)

Country Link
EP (2) EP1240905B3 (pt)
JP (1) JP3980652B2 (pt)
KR (1) KR100518044B1 (pt)
CN (1) CN1130226C (pt)
AR (1) AR011509A1 (pt)
AT (2) ATE222773T1 (pt)
AU (1) AU710475B2 (pt)
BR (2) BR9712917A (pt)
CA (1) CA2271008C (pt)
CO (1) CO4910171A1 (pt)
CY (2) CY2407B1 (pt)
CZ (1) CZ295954B6 (pt)
DE (3) DE69715031T2 (pt)
DK (2) DK1240905T5 (pt)
ES (2) ES2182131T3 (pt)
GB (1) GB9623233D0 (pt)
HK (2) HK1022638A1 (pt)
HU (1) HU224126B1 (pt)
IL (1) IL129530A (pt)
LU (1) LU91183I2 (pt)
NO (2) NO320186B1 (pt)
NZ (1) NZ335384A (pt)
PL (1) PL188460B1 (pt)
PT (2) PT941117E (pt)
SA (1) SA98181128B1 (pt)
SI (2) SI1240905T1 (pt)
TR (1) TR199900979T2 (pt)
TW (1) TW471971B (pt)
WO (1) WO1998019702A1 (pt)
ZA (1) ZA979984B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1004314A1 (fr) * 1998-11-26 2000-05-31 Pasteur Merieux MSD Vaccin T.d. Polio rappel pour une population vaccinée ou sensibilisée
KR100374813B1 (ko) * 2000-04-07 2003-03-03 녹십자백신 주식회사 디프테리아, 파상풍 톡소이드, 정제백일해 및비형간염표면항원을 포함한 4가 혼합백신 및 그 제조 방법
GB0108364D0 (en) * 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
KR100401423B1 (ko) * 2001-01-10 2003-10-17 주식회사 엘지생명과학 혼합 백신의 제조 방법
JP5007425B2 (ja) * 2006-01-30 2012-08-22 財団法人ヒューマンサイエンス振興財団 百日咳ワクチンの安全性評価方法
GB0616306D0 (en) * 2006-08-16 2006-09-27 Novartis Ag Vaccines
GB0822633D0 (en) * 2008-12-11 2009-01-21 Novartis Ag Formulation
MX2012002723A (es) 2009-09-02 2012-04-11 Novartis Ag Composiciones inmunogenicas que incluyen moduladores de la actividad de receptores tipo toll.
WO2012031140A1 (en) 2010-09-01 2012-03-08 Novartis Ag Adsorption of immunopotentiators to insoluble metal salts
EP2680885B8 (en) 2011-03-02 2018-07-25 GlaxoSmithKline Biologicals SA Combination vaccines with lower doses of antigen and/or adjuvant
CN102363041A (zh) * 2011-11-17 2012-02-29 成都欧林生物科技股份有限公司 不含防腐剂疫苗的制作工艺
EP2822581A2 (en) 2012-03-08 2015-01-14 Novartis AG Adjuvanted formulations of dtp booster vaccines
CN102793915B (zh) * 2012-07-25 2013-10-23 天津康希诺生物技术有限公司 一种无细胞百日咳疫苗的生产方法
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
JP2015525794A (ja) 2012-08-06 2015-09-07 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 乳児においてｒｓｖ及び百日咳菌に対する免疫応答を惹起するための方法
CN103100081A (zh) * 2012-12-26 2013-05-15 天津康希诺生物技术有限公司 一种多价联合疫苗
BR112015021523A8 (pt) 2013-03-08 2021-06-29 Crucell Holland Bv composição de uma vacina contra a tosse convulsa acelular, e, usos da composição e de antígenos da bordetella pertussis
AU2014304545A1 (en) 2013-08-05 2016-02-25 Glaxosmithkline Biologicals S.A. Combination immunogenic compositions
CN114748616A (zh) * 2022-05-23 2022-07-15 中国医学科学院医学生物学研究所 一种成人青少年用无细胞百白破联合疫苗及其制备方法
CN117417419B (zh) * 2023-01-10 2024-04-19 康希诺生物股份公司 一种百日咳毒素脱毒方法及无细胞百白破联合疫苗

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI861417A0 (fi) 1985-04-15 1986-04-01 Endotronics Inc Hepatitis b ytantigen framstaelld med rekombinant-dna-teknik, vaccin, diagnostiskt medel och cellinjer samt foerfaranden foer framstaellning daerav.
US4895800A (en) 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
AP56A (en) 1987-01-30 1989-09-26 Smithkline Biologicals S A Hepatitis B virus surface antigens and hybrid antigehs containing them.
EP0304578B1 (en) 1987-06-22 2001-10-24 Medeva Holdings Bv Peptide comprising hepatitis B surface antigen
ATE105858T1 (de) 1987-07-17 1994-06-15 Rhein Biotech Ges Fuer Biotech Dna-moleküle, die für fmdh-kontrollabschnitte und strukturgene für ein protein mit fmdh-aktivität kodieren, sowie deren anwendung.
SG48175A1 (en) 1989-07-25 1998-04-17 Smithkline Beecham Biolog Novel antigens and method for their preparation
GB9007024D0 (en) 1990-03-29 1990-05-30 Imperial College Novel vaccine
EP2289548A3 (en) 1992-05-23 2012-08-08 GlaxoSmithKline Biologicals S.A. Combined vaccines comprising hepatitis B surface antigen and other antigens

Also Published As

Publication number Publication date
JP2001503422A (ja) 2001-03-13
HK1050473B (zh) 2006-03-03
NO2006005I2 (no) 2010-04-12
LU91183I2 (fr) 2005-09-20
PT1240905E (pt) 2005-09-30
NO320186B1 (no) 2005-11-07
HU224126B1 (hu) 2005-05-30
EP1240905A1 (en) 2002-09-18
SI1240905T1 (en) 2005-10-31
NO992156D0 (no) 1999-05-04
AR011509A1 (es) 2000-08-30
CN1130226C (zh) 2003-12-10
CY2407B1 (en) 2004-09-10
SA98181128B1 (ar) 2006-03-25
IL129530A0 (en) 2000-02-29
ES2240647T7 (es) 2010-03-31
EP1240905B1 (en) 2005-05-11
CZ164099A3 (cs) 1999-10-13
DK0941117T3 (da) 2002-11-18
ES2240647T3 (es) 2005-10-16
GB9623233D0 (en) 1997-01-08
PL333127A1 (en) 1999-11-22
CN1236321A (zh) 1999-11-24
CA2271008C (en) 2008-07-22
CZ295954B6 (cs) 2005-12-14
JP3980652B2 (ja) 2007-09-26
NO2006005I1 (no) 2006-05-08
PT941117E (pt) 2002-12-31
AU5319698A (en) 1998-05-29
DE69733285D1 (de) 2005-06-16
AU710475B2 (en) 1999-09-23
BRPI9712917B1 (pt) 2019-12-03
EP0941117B1 (en) 2002-08-28
HUP9904287A1 (hu) 2000-04-28
PL188460B1 (pl) 2005-02-28
HK1050473A1 (en) 2003-06-27
DE69733285T3 (de) 2010-03-25
KR20000053092A (ko) 2000-08-25
ES2182131T3 (es) 2003-03-01
NZ335384A (en) 2000-10-27
ZA979984B (en) 1998-07-23
HUP9904287A3 (en) 2001-05-28
CO4910171A1 (es) 2000-04-24
KR100518044B1 (ko) 2005-09-30
TR199900979T2 (xx) 1999-07-21
CY2568B1 (en) 2008-07-02
DE69715031T2 (de) 2003-05-08
DK1240905T5 (da) 2010-01-11
EP1240905B3 (en) 2009-08-26
DE69715031D1 (de) 2002-10-02
EP0941117A1 (en) 1999-09-15
ATE222773T1 (de) 2002-09-15
DE122005000046I1 (de) 2005-12-29
SI0941117T1 (en) 2002-12-31
ATE295178T1 (de) 2005-05-15
CA2271008A1 (en) 1998-05-14
WO1998019702A1 (en) 1998-05-14
HK1022638A1 (en) 2000-08-18
IL129530A (en) 2005-11-20
DK1240905T3 (da) 2005-07-18
DE69733285T2 (de) 2006-01-12
BRPI9712917B8 (pt) 2021-05-25
TW471971B (en) 2002-01-11
NO992156L (no) 1999-05-04

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Legal Events

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B06A Patent application procedure suspended [chapter 6.1 patent gazette]
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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B25D Requested change of name of applicant approved

Owner name: GLAXOSMITHKLINE BIOLOGICALS S.A. (BE)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

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