HK1048318B - 取代的3-苯基-5-烷氧基-1，3，4-噁二唑-2-酮及其作為脂酶抑制劑的用途 - Google Patents

取代的3-苯基-5-烷氧基-1，3，4-噁二唑-2-酮及其作為脂酶抑制劑的用途 Download PDF

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Publication number
HK1048318B
HK1048318B HK03100568.9A HK03100568A HK1048318B HK 1048318 B HK1048318 B HK 1048318B HK 03100568 A HK03100568 A HK 03100568A HK 1048318 B HK1048318 B HK 1048318B
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HK
Hong Kong
Prior art keywords
substituted
alkyl
phenyl
unsubstituted
oxadiazol
Prior art date
Application number
HK03100568.9A
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English (en)
Chinese (zh)
Other versions
HK1048318A1 (en
Inventor
S‧佩特里
S‧佩特裡
K‧舍恩芬杰
G‧穆勒
K‧舍恩芬傑
K-H‧巴林豪斯
Original Assignee
萨诺费－阿文蒂斯德国有限公司
薩諾費-阿文蒂斯德國有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 萨诺费－阿文蒂斯德国有限公司, 薩諾費-阿文蒂斯德國有限公司 filed Critical 萨诺费－阿文蒂斯德国有限公司
Publication of HK1048318A1 publication Critical patent/HK1048318A1/xx
Publication of HK1048318B publication Critical patent/HK1048318B/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK03100568.9A 1999-09-04 2000-08-22 取代的3-苯基-5-烷氧基-1，3，4-噁二唑-2-酮及其作為脂酶抑制劑的用途 HK1048318B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19942354.7 1999-09-04
DE19942354A DE19942354A1 (de) 1999-09-04 1999-09-04 Substituierte 3-Phenyl-5-alkoxi-1,3,4-oxdiazol-2-one, ihre Herstellung und Verwendung in Arzneimitteln
PCT/EP2000/008150 WO2001017981A1 (de) 1999-09-04 2000-08-22 Substituierte 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-one und ihre verwendung als lipase-hemmer

Publications (2)

Publication Number Publication Date
HK1048318A1 HK1048318A1 (en) 2003-03-28
HK1048318B true HK1048318B (zh) 2004-12-10

Family

ID=7920884

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03100568.9A HK1048318B (zh) 1999-09-04 2000-08-22 取代的3-苯基-5-烷氧基-1，3，4-噁二唑-2-酮及其作為脂酶抑制劑的用途

Country Status (30)

Country Link
US (1) US6596742B1 (https=)
EP (1) EP1214302B1 (https=)
JP (1) JP2003508522A (https=)
KR (1) KR100723817B1 (https=)
CN (1) CN1152024C (https=)
AR (1) AR032430A1 (https=)
AT (1) ATE253059T1 (https=)
AU (1) AU781330B2 (https=)
BR (1) BR0013765A (https=)
CA (1) CA2383731A1 (https=)
CZ (1) CZ2002772A3 (https=)
DE (2) DE19942354A1 (https=)
DK (1) DK1214302T3 (https=)
EE (1) EE04811B1 (https=)
ES (1) ES2204685T3 (https=)
HK (1) HK1048318B (https=)
HR (1) HRP20020187A2 (https=)
HU (1) HUP0202988A3 (https=)
IL (2) IL148275A0 (https=)
MX (1) MXPA02001834A (https=)
NO (1) NO323129B1 (https=)
NZ (1) NZ517551A (https=)
PL (1) PL197314B1 (https=)
PT (1) PT1214302E (https=)
RU (1) RU2265600C2 (https=)
SK (1) SK285924B6 (https=)
TR (1) TR200200553T2 (https=)
WO (1) WO2001017981A1 (https=)
YU (1) YU10402A (https=)
ZA (1) ZA200201594B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10102265C1 (de) * 2001-01-18 2002-08-08 Aventis Pharma Gmbh Substituierte 3-Phenyl-5-alkoxi-1,3,4-oxdiazol-2-one, ihre Herstellung und Verwendung in Arzneistoffen
DE10208987A1 (de) * 2002-02-28 2003-09-11 Aventis Pharma Gmbh Substituierte 3-Phenyl-5-alkoxi-1,3,4-oxidiazol-2-one, ihre Herstellung und Verwendung in Arzneistoffen
DE10208986A1 (de) * 2002-02-28 2003-09-11 Aventis Pharma Gmbh Verwendung substituierter 3-Phenyl-5-alkoxi-1,3,4-oxdiazol-2-one zur Herstellung von Arzneimitteln mit hemmender Wirkung an der pankreatischen Lipase
US6900233B2 (en) 2002-02-28 2005-05-31 Aventis Pharma Deutschland Gmbh Substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadiazol-2-ones, pharmaceutical composition and method for treating obesity thereof
DE10247680B4 (de) * 2002-10-12 2005-09-01 Aventis Pharma Deutschland Gmbh Neue bicyclische Inhibitoren der Hormon Sensitiven Lipase
US7208504B2 (en) 2002-10-12 2007-04-24 Sanofi-Aventis Deutschland Gmbh Bicyclic inhibitors of hormone sensitive lipase
MX2007004488A (es) * 2004-10-13 2007-09-11 Wyeth Corp Analogos de anilino-pirimidina n-bencenosulfonilo sustituidos.
EP2178821A2 (en) * 2007-07-12 2010-04-28 Deviris Inc. Hormone sensitive lipase modulators and methods of use
BRPI0821482A2 (pt) * 2007-12-27 2015-07-14 Bial Portela & Ca Sa 3-n-fenil-1,3,4-oxadiazolona 5-o-substituída, seu uso, sua composição e seu processo de preparação
AR074978A1 (es) 2008-12-23 2011-03-02 Bial Portela & Ca Sa 3-n-aril-1,3,4-oxadiazolonas 5-o-sustituidas para uso en el tratamiento del dolor y procedimiento de obtencion
US8501768B2 (en) * 2011-05-17 2013-08-06 Hoffmann-La Roche Inc. Hexahydrocyclopentapyrrolone, hexahydropyrrolopyrrolone, octahydropyrrolopyridinone and octahydropyridinone compounds
CN114163351B (zh) * 2020-09-11 2024-01-23 江苏优嘉植物保护有限公司 噁虫酮中间体2-(2-甲氧基)苯肼甲酸甲酯合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB518042A (en) 1937-09-15 1940-02-15 Ljungstroms Angturbin Ab Improvements in elastic fluid turbines of the double rotation type
US4076824A (en) 1975-02-03 1978-02-28 Rhone-Poulenc Industries Anthelmintic oxadiazolinone derivatives
FR2299328A1 (fr) 1975-02-03 1976-08-27 Rhone Poulenc Ind Derives de l'alcoyloxy-5 phenyl-3 oxyde azo
FR2299028A1 (fr) 1975-02-03 1976-08-27 Rhone Poulenc Ind Nouvea
DK156439C (da) 1980-09-15 1990-01-22 Shell Int Research 7-substituerede 2,3-dihydrobenzofuranderivater samt pesticidpraeparater indeholdende disse og en fremgangsmaade til bekaempelse af skadelige organismer
EP0067471B1 (en) 1981-06-15 1985-11-06 Shell Internationale Researchmaatschappij B.V. 7-substituted 2,3-dihydrobenzofurans, their preparation and their use as pesticides or as chemical intermediates
JPS60115502A (ja) * 1983-11-28 1985-06-22 Mitsubishi Chem Ind Ltd 殺虫剤
DE3931843A1 (de) 1989-09-23 1991-04-04 Bayer Ag Substituierte 1,3,4-oxa(thia)diazolinone verfahren zu ihrer herstellung und ihre verwendung der bekaempfung von endoparasiten
US5236939A (en) 1989-09-23 1993-08-17 Bayer Aktiengesellschaft Substituted 1,3,4-oxa(thia)diazolinones process for their preparation and their use of combating endoparasites
US5641796A (en) * 1994-11-01 1997-06-24 Eli Lilly And Company Oral hypoglycemic agents

Also Published As

Publication number Publication date
KR20020024336A (ko) 2002-03-29
ATE253059T1 (de) 2003-11-15
NZ517551A (en) 2003-10-31
SK285924B6 (sk) 2007-11-02
IL148275A0 (en) 2002-09-12
CZ2002772A3 (cs) 2002-05-15
EP1214302B1 (de) 2003-10-29
HUP0202988A2 (hu) 2002-12-28
DK1214302T3 (da) 2004-02-16
EP1214302A1 (de) 2002-06-19
IL148275A (en) 2008-08-07
CN1371369A (zh) 2002-09-25
MXPA02001834A (es) 2002-08-12
PT1214302E (pt) 2004-03-31
NO20021007D0 (no) 2002-02-28
HUP0202988A3 (en) 2004-12-28
CA2383731A1 (en) 2001-03-15
ZA200201594B (en) 2003-04-30
CN1152024C (zh) 2004-06-02
TR200200553T2 (tr) 2002-06-21
JP2003508522A (ja) 2003-03-04
US6596742B1 (en) 2003-07-22
ES2204685T3 (es) 2004-05-01
KR100723817B1 (ko) 2007-06-04
PL353214A1 (en) 2003-11-03
NO323129B1 (no) 2007-01-08
RU2265600C2 (ru) 2005-12-10
YU10402A (sh) 2004-11-25
AR032430A1 (es) 2003-11-12
BR0013765A (pt) 2002-04-30
HK1048318A1 (en) 2003-03-28
AU781330B2 (en) 2005-05-19
EE04811B1 (et) 2007-04-16
HRP20020187A2 (en) 2004-02-29
DE50004274D1 (de) 2003-12-04
SK3012002A3 (en) 2002-06-04
EE200200109A (et) 2003-06-16
AU7411200A (en) 2001-04-10
PL197314B1 (pl) 2008-03-31
DE19942354A1 (de) 2001-03-08
NO20021007L (no) 2002-02-28
WO2001017981A1 (de) 2001-03-15

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090822