HK1038691B - Antibiotic compositions for treatment of the eye - Google Patents

Antibiotic compositions for treatment of the eye Download PDF

Info

Publication number
HK1038691B
HK1038691B HK02100003.3A HK02100003A HK1038691B HK 1038691 B HK1038691 B HK 1038691B HK 02100003 A HK02100003 A HK 02100003A HK 1038691 B HK1038691 B HK 1038691B
Authority
HK
Hong Kong
Prior art keywords
inflammatory agent
agent comprises
use according
dexamethasone
topical composition
Prior art date
Application number
HK02100003.3A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1038691A1 (en
Inventor
Cagle Gerald
L. Abshire Robert
W. Stroman David
M. Yanni John
Original Assignee
Alcon, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26799441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1038691(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon, Inc. filed Critical Alcon, Inc.
Priority to HK04102444.4A priority Critical patent/HK1059572B/en
Publication of HK1038691A1 publication Critical patent/HK1038691A1/en
Publication of HK1038691B publication Critical patent/HK1038691B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK02100003.3A 1998-09-30 1999-09-29 Antibiotic compositions for treatment of the eye HK1038691B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HK04102444.4A HK1059572B (en) 1998-09-30 2002-01-02 Antibiotic compositions containing moxifloxacin for treatment of the eye

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US102504 1979-12-11
US102506 1987-09-28
US10250698P 1998-09-30 1998-09-30
US10250498P 1998-09-30 1998-09-30
PCT/US1999/022622 WO2000018386A2 (en) 1998-09-30 1999-09-29 Antibiotic compositions for treatment of the eye, ear and nose

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK04102444.4A Division HK1059572B (en) 1998-09-30 2002-01-02 Antibiotic compositions containing moxifloxacin for treatment of the eye

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK04102444.4A Addition HK1059572B (en) 1998-09-30 2002-01-02 Antibiotic compositions containing moxifloxacin for treatment of the eye

Publications (2)

Publication Number Publication Date
HK1038691A1 HK1038691A1 (en) 2002-03-28
HK1038691B true HK1038691B (en) 2004-04-23

Family

ID=26799441

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02100003.3A HK1038691B (en) 1998-09-30 1999-09-29 Antibiotic compositions for treatment of the eye

Country Status (18)

Country Link
EP (5) EP2796138B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (5) JP2002525317A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR101463243B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (2) CN100374114C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (2) AR020661A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (2) ATE254458T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU762827B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BRPI9914151B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (3) CA2342211C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CY (3) CY1111404T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE69912972T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (5) DK1117401T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (4) ES2207307T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK1038691B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (5) PT1384478E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TR (2) TR200100883T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TWI222361B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2000018386A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (37)

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Publication number Priority date Publication date Assignee Title
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
DE19937115A1 (de) 1999-08-06 2001-02-08 Bayer Ag Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
WO2001022936A1 (en) 1999-09-24 2001-04-05 Alcon Universal Ltd. Topical suspension formulations containing ciprofloxacin and dexamethasone
DE19962470A1 (de) * 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
WO2001089495A2 (en) * 2000-05-19 2001-11-29 Alcon Laboratories, Inc. Antibiotic compositions containing quinolone derivatives for treatment of the eye, ear and nose
CA2412575C (en) 2000-07-26 2009-12-29 Onkar N. Singh Improved process for manufacturing compositions containing ciprofloxacin and hydrocortisone
JPWO2002040028A1 (ja) * 2000-11-16 2004-03-18 わかもと製薬株式会社 抗菌ゲル化点眼剤
AU2002228660A1 (en) 2000-12-20 2002-07-01 Alcon, Inc Use of amidoamines to treat or prevent acanthamoeba and fungal infections
AU2002226926A1 (en) * 2000-12-20 2002-07-01 Alcon, Inc. Antifungal compositions containing an antibiotic and one or more amidoamines
EP1429780B1 (en) 2001-09-21 2005-12-21 Alcon, Inc. Method of treating middle ear infections
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
ES2424676T3 (es) 2003-09-10 2013-10-07 Kyorin Pharmaceutical Co., Ltd. Derivado de ácido 7-(3-ciclopropilaminometil-1-pirrolidinil 4-sustituido)quinoloncarboxílico
WO2006015545A1 (fr) * 2004-08-11 2006-02-16 Shenzhen Tys R & D Co., Ltd. Capsule de gelatine de moxifloxacin et procede pour sa preparation
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TWI544934B (zh) * 2008-06-09 2016-08-11 愛爾康研究有限公司 含有氟喹諾酮抗生素藥物之經改良藥學組成物
AU2010266120B2 (en) * 2009-07-02 2014-02-06 Curofin Pharma Gmbh Compositions comprising finafloxacin and methods for treating ophthalmic, otic, or nasal infections
MX337419B (es) * 2010-01-07 2016-03-03 Univ Minnesota Metodos y composiciones para aplicar moxifloxacina al oido.
BR112014012885A2 (pt) 2011-12-06 2017-06-13 Alcon Res Ltd composição de gel celulósica com estabilidade de viscosidade aperfeiçoada
RU2472507C1 (ru) * 2012-02-01 2013-01-20 Закрытое акционерное общество "Брынцалов-А" Водный состав на основе моксифлоксацина для парентерального введения
US9504691B2 (en) 2012-12-06 2016-11-29 Alcon Research, Ltd. Finafloxacin suspension compositions
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
CN104224802B (zh) * 2014-09-19 2017-12-12 南京优科生物医药研究有限公司 一种盐酸莫西沙星滴耳剂及其制备方法
RU2595837C2 (ru) * 2014-09-29 2016-08-27 Открытое Акционерное Общество "Татхимфармпрепараты" Состав и способ получения глазных капель
US20180311225A1 (en) * 2015-10-29 2018-11-01 Teika Pharmaceutical Co., Ltd. External preparation
WO2019193513A1 (en) * 2018-04-03 2019-10-10 Hyderabad Eye Research Foundation Mucoadhesive drug delivery system for ocular administration of fluoroquinolone antibiotics
IT201900005280A1 (it) * 2019-04-05 2020-10-05 Ntc S R L Composizione otologica
CA3182196A1 (en) * 2020-06-10 2021-12-16 Anthony Sampietro Compositions and uses in method for post-operative ocular care
CN116270662A (zh) * 2021-12-03 2023-06-23 苏州欧康维视生物科技有限公司 盐酸莫西沙星地塞米松磷酸钠滴眼液
KR102656260B1 (ko) 2022-10-14 2024-04-09 주식회사태준제약 목시플록사신을 포함하는 안과용 조성물

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JPH085779B2 (ja) * 1989-09-22 1996-01-24 杏林製薬株式会社 フレロキサシン点眼液
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JP3337218B2 (ja) 1992-05-06 2002-10-21 アルコン ラボラトリーズ，インコーポレイテッド 眼科用組成物におけるホウ酸塩−ポリオール複合体の使用
DE4424369A1 (de) * 1994-07-11 1996-01-18 Bayer Ag Pyrido[3,2,1.i,j][3,1]benzoxazinderivate
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ATE214931T1 (de) * 1995-06-06 2002-04-15 Bayer Ag Antibakterielle präparate für die ohren ohne irritierende, sensibilisierende und ototoxische wirkungen
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AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
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Also Published As

Publication number Publication date
ES2602956T3 (es) 2017-02-23
DE69943287D1 (de) 2011-04-28
JP5563041B2 (ja) 2014-07-30
JP2014144982A (ja) 2014-08-14
PT1384478E (pt) 2011-05-12
AU762827B2 (en) 2003-07-03
BRPI9914151B1 (pt) 2017-10-03
JP2013018799A (ja) 2013-01-31
TR200100883T2 (tr) 2001-10-22
ATE254458T1 (de) 2003-12-15
DE69912972T2 (de) 2004-04-22
WO2000018386A2 (en) 2000-04-06
CY1115916T1 (el) 2017-01-25
EP1384478B1 (en) 2011-03-16
CY1111404T1 (el) 2015-08-05
EP2796138B1 (en) 2016-08-17
JP2012067141A (ja) 2012-04-05
PT1117401E (pt) 2004-03-31
DK2269602T3 (en) 2014-12-15
CA2342211A1 (en) 2000-04-06
EP1384478A1 (en) 2004-01-28
AU1310100A (en) 2000-04-17
KR20010075138A (ko) 2001-08-09
CA2774207A1 (en) 2000-04-06
DK1117401T3 (da) 2004-02-23
AR020661A1 (es) 2002-05-22
HK1150769A1 (en) 2012-01-13
CN100374114C (zh) 2008-03-12
BRPI9914151B8 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2021-05-25
ES2526521T3 (es) 2015-01-13
JP2002525317A (ja) 2002-08-13
KR101463243B1 (ko) 2014-12-17
DK2301541T3 (da) 2014-09-01
CN1650863A (zh) 2005-08-10
EP2796138A1 (en) 2014-10-29
ES2519190T3 (es) 2014-11-06
CN1320035A (zh) 2001-10-31
AR081393A2 (es) 2012-08-29
EP2301541A1 (en) 2011-03-30
PT2269602E (pt) 2014-12-29
EP1117401B1 (en) 2003-11-19
WO2000018386A3 (en) 2000-06-08
ES2207307T3 (es) 2004-05-16
HK1059572A1 (en) 2004-07-09
JP2009007375A (ja) 2009-01-15
CA2342211C (en) 2009-05-26
BR9914151A (pt) 2001-06-26
PT2796138T (pt) 2016-09-22
ATE501732T1 (de) 2011-04-15
EP2301541B1 (en) 2014-08-20
EP2269602A1 (en) 2011-01-05
DK2796138T3 (en) 2016-12-05
TR200704370T2 (tr) 2007-11-21
CY1115759T1 (el) 2017-01-25
EP1117401A2 (en) 2001-07-25
PT2301541E (pt) 2014-10-29
TWI222361B (en) 2004-10-21
CA2659064A1 (en) 2000-04-06
HK1150756A1 (en) 2012-01-13
HK1038691A1 (en) 2002-03-28
DK1384478T3 (da) 2011-05-23
EP2269602B1 (en) 2014-11-19
DE69912972D1 (de) 2003-12-24
CN1184968C (zh) 2005-01-19

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