HK1036653A1 - Improved immunodiagnostic assays using reducing agents. - Google Patents

Improved immunodiagnostic assays using reducing agents.

Info

Publication number
HK1036653A1
HK1036653A1 HK01105349A HK01105349A HK1036653A1 HK 1036653 A1 HK1036653 A1 HK 1036653A1 HK 01105349 A HK01105349 A HK 01105349A HK 01105349 A HK01105349 A HK 01105349A HK 1036653 A1 HK1036653 A1 HK 1036653A1
Authority
HK
Hong Kong
Prior art keywords
recombinant protein
purification
recombinant
reducing agents
dtt
Prior art date
Application number
HK01105349A
Other languages
English (en)
Inventor
Geert Maertens
Joost Louwagie
Alfons Bosman
Erwin Sablon
Maan Zrein
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8237028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1036653(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Publication of HK1036653A1 publication Critical patent/HK1036653A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
HK01105349A 1998-04-17 2001-07-31 Improved immunodiagnostic assays using reducing agents. HK1036653A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98870087 1998-04-17
PCT/EP1999/002547 WO1999054735A1 (en) 1998-04-17 1999-04-15 Improved immunodiagnostic assays using reducing agents

Publications (1)

Publication Number Publication Date
HK1036653A1 true HK1036653A1 (en) 2002-01-11

Family

ID=8237028

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01105349A HK1036653A1 (en) 1998-04-17 2001-07-31 Improved immunodiagnostic assays using reducing agents.

Country Status (22)

Country Link
US (1) US7935490B2 (ja)
EP (2) EP1471074B1 (ja)
JP (2) JP2002512370A (ja)
KR (1) KR20010042807A (ja)
CN (1) CN1305589A (ja)
AT (2) ATE278960T1 (ja)
AU (1) AU751362B2 (ja)
BR (1) BRPI9909678B8 (ja)
CA (2) CA2324970C (ja)
CY (1) CY1108424T1 (ja)
CZ (1) CZ298268B6 (ja)
DE (2) DE69920895T3 (ja)
DK (2) DK1071955T4 (ja)
ES (2) ES2230851T5 (ja)
HK (1) HK1036653A1 (ja)
HU (1) HUP0101719A3 (ja)
IL (1) IL138791A0 (ja)
PL (1) PL343469A1 (ja)
PT (2) PT1071955E (ja)
TR (4) TR200101647T2 (ja)
WO (1) WO1999054735A1 (ja)
ZA (1) ZA200005445B (ja)

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EP1090033B2 (en) * 1998-06-24 2007-12-19 Innogenetics N.V. Particles of hcv envelope proteins: use for vaccination
JP5175417B2 (ja) * 2000-08-17 2013-04-03 トリペップ アクチ ボラゲット リバビリンを含むワクチンおよびその使用方法
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
EP1417298A2 (en) 2001-04-24 2004-05-12 Innogenetics N.V. Core-glycosylated hcv envelope proteins
JP2004108914A (ja) * 2002-09-18 2004-04-08 Kudo Norio コラーゲンの測定方法
JP2006516955A (ja) * 2002-11-08 2006-07-13 イノジェネティックス・ナムローゼ・フェンノートシャップ Ｅ１ペプチド及びｎｓ３ペプチドを含むｈｃｖワクチン組成物
US20050014136A1 (en) * 2003-05-28 2005-01-20 Innogenetics N.V. Modified HCV NS5
US8546075B2 (en) * 2003-10-28 2013-10-01 Advanced Life Science Institute, Inc. Method of detecting hepatitis C virus
JP2009543099A (ja) * 2006-07-07 2009-12-03 ポール・コーポレーション 親和性捕捉中の変性剤の使用
MX2010000745A (es) * 2007-07-16 2010-05-20 Pfizer Procedimientos para mejorar un indice de marcador genomico de animales lecheros y productos lacteos.
BRPI0816776A2 (pt) * 2007-09-12 2019-09-24 Pfizer métodos para usar marcadores genéticos e interações epistáticas relacionadas
MX2010003610A (es) * 2007-10-03 2010-04-30 Pfizer Marcadores geneticos para ganado astado y sin cuernos, y metodos relacionados.
CA2708273A1 (en) * 2007-12-17 2009-07-09 Pfizer Inc. Methods of improving genetic profiles of dairy animals and products
WO2010006604A1 (en) * 2008-07-16 2010-01-21 Radiometer Medical Aps High capacity solid phase
CN102081018A (zh) * 2009-11-30 2011-06-01 希森美康株式会社 样品的预处理方法及hcv的免疫测定方法
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
US10088483B2 (en) 2014-10-29 2018-10-02 Abbott Laboratories Subject anti-HCV antibody detection assays employing NS3 capture peptides
CN109870581B (zh) * 2017-12-04 2021-05-04 厦门万泰凯瑞生物技术有限公司 一种定量检测HBsAg的试剂盒及方法
CN109678954B (zh) * 2018-12-29 2022-01-07 山东莱博生物科技有限公司 一对能够特异性识别hcv ns3蛋白的单克隆抗体及其应用
CN110988362B (zh) * 2019-12-20 2023-11-14 迈克生物股份有限公司 抗组蛋白抗体测定试剂、试剂盒及其使用方法
CN112225783B (zh) * 2020-09-16 2021-08-31 东莞市朋志生物科技有限公司 Hcv重组抗原及其突变体
CN112285361B (zh) * 2020-09-27 2023-12-05 中国人民解放军空军军医大学 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂
CN113219169B (zh) * 2021-05-22 2021-12-17 北京金诺百泰生物技术有限公司 生物检测用封闭剂及其制备方法、包被板及应用该包被板的试剂盒
CN115112897B (zh) * 2021-12-10 2024-11-01 中山大学附属第八医院（深圳福田） 一种用于鉴别抗体检测生物学假阳性的方法

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EP0139526A2 (en) * 1983-10-20 1985-05-02 Warner-Lambert Company An insolubilized stable specific binding protein
US4616078A (en) * 1985-04-08 1986-10-07 Eli Lilly And Company Process for purifying proinsulin-like materials
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Also Published As

Publication number Publication date
EP1471074A3 (en) 2004-11-10
TR200101647T2 (tr) 2002-06-21
EP1071955B1 (en) 2004-10-06
TR200003024T2 (tr) 2000-12-21
US7935490B2 (en) 2011-05-03
ATE401340T1 (de) 2008-08-15
EP1071955A1 (en) 2001-01-31
CA2324970A1 (en) 1999-10-28
ES2230851T3 (es) 2005-05-01
CZ298268B6 (cs) 2007-08-08
DE69920895D1 (de) 2004-11-11
BR9909678A (pt) 2000-12-19
JP3974620B2 (ja) 2007-09-12
DK1071955T4 (da) 2009-06-15
CA2658218C (en) 2014-10-28
AU3817199A (en) 1999-11-08
CN1305589A (zh) 2001-07-25
DK1471074T3 (da) 2008-11-17
EP1071955B2 (en) 2009-02-18
PL343469A1 (en) 2001-08-13
BRPI9909678B8 (pt) 2021-05-25
KR20010042807A (ko) 2001-05-25
DK1071955T3 (da) 2005-02-07
ZA200005445B (en) 2003-01-06
TR200202213T2 (tr) 2002-11-21
ES2230851T5 (es) 2009-06-25
ATE278960T1 (de) 2004-10-15
US20060263854A1 (en) 2006-11-23
PT1071955E (pt) 2005-02-28
JP2005185285A (ja) 2005-07-14
CA2324970C (en) 2009-06-30
JP2002512370A (ja) 2002-04-23
CY1108424T1 (el) 2014-04-09
DE69920895T3 (de) 2009-09-03
EP1471074B1 (en) 2008-07-16
IL138791A0 (en) 2001-10-31
TR200101648T2 (tr) 2002-06-21
CZ20003819A3 (cs) 2001-10-17
ES2310701T3 (es) 2009-01-16
WO1999054735A1 (en) 1999-10-28
EP1471074A2 (en) 2004-10-27
CA2658218A1 (en) 1999-10-28
HUP0101719A2 (hu) 2001-09-28
DE69939132D1 (de) 2008-08-28
AU751362B2 (en) 2002-08-15
PT1471074E (pt) 2008-10-23
BR9909678B1 (pt) 2013-11-12
HUP0101719A3 (en) 2006-05-29
DE69920895T2 (de) 2005-10-13

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20170415