HK1031255A1 - Use of anti-embryonic hemoglobin antibodies to identify fetal cells - Google Patents

Use of anti-embryonic hemoglobin antibodies to identify fetal cells

Info

Publication number
HK1031255A1
HK1031255A1 HK00108086A HK00108086A HK1031255A1 HK 1031255 A1 HK1031255 A1 HK 1031255A1 HK 00108086 A HK00108086 A HK 00108086A HK 00108086 A HK00108086 A HK 00108086A HK 1031255 A1 HK1031255 A1 HK 1031255A1
Authority
HK
Hong Kong
Prior art keywords
fetal
fetal cells
proteins
embryonic hemoglobin
determining
Prior art date
Application number
HK00108086A
Other languages
English (en)
Inventor
Mitchell Golbus
Original Assignee
Applied Imaging Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Imaging Inc filed Critical Applied Imaging Inc
Publication of HK1031255A1 publication Critical patent/HK1031255A1/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • G01N2800/368Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK00108086A 1996-10-21 2000-12-14 Use of anti-embryonic hemoglobin antibodies to identify fetal cells HK1031255A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/734,556 US5731156A (en) 1996-10-21 1996-10-21 Use of anti-embryonic hemoglobin antibodies to identify fetal cells
PCT/US1997/019447 WO1998018005A1 (en) 1996-10-21 1997-10-20 Use of anti-embryonic hemoglobin antibodies to identify fetal cells

Publications (1)

Publication Number Publication Date
HK1031255A1 true HK1031255A1 (en) 2001-06-08

Family

ID=24952172

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00108086A HK1031255A1 (en) 1996-10-21 2000-12-14 Use of anti-embryonic hemoglobin antibodies to identify fetal cells

Country Status (14)

Country Link
US (1) US5731156A (xx)
EP (1) EP1007965B1 (xx)
JP (1) JP4091123B2 (xx)
KR (1) KR100523381B1 (xx)
CN (1) CN1234117A (xx)
AT (1) ATE290210T1 (xx)
AU (1) AU735380B2 (xx)
BR (1) BR9712548A (xx)
CA (1) CA2269327A1 (xx)
DE (1) DE69732662T2 (xx)
HK (1) HK1031255A1 (xx)
IL (1) IL129382A (xx)
RU (1) RU2178703C2 (xx)
WO (1) WO1998018005A1 (xx)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509192B1 (en) * 1992-02-24 2003-01-21 Coulter International Corp. Quality control method
US5629147A (en) * 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
US6718053B1 (en) * 1996-11-27 2004-04-06 Chromavision Medical Systems, Inc. Method and apparatus for automated image analysis of biological specimens
JP2000501184A (ja) * 1995-11-30 2000-02-02 クロマビジョン メディカル システムズ,インコーポレイテッド 生体標本の自動画像分析の方法および装置
EP0974056B1 (en) * 1997-03-08 2005-11-02 The University of Dundee Prenatal diagnostic methods in vitro
US5962234A (en) * 1997-10-20 1999-10-05 Applied Imaging Corporation Use of anti-embryonic epsilon hemoglobin antibodies to identify fetal cells
CN1702459A (zh) * 1998-05-09 2005-11-30 伊康尼西斯公司 用于包括胎儿细胞的计算机所控制的稀少细胞的基于诊断的方法和装置
FR2781055B1 (fr) * 1998-07-09 2000-10-13 Immunotech Sa Reactif et methode pour la permeabilisation et l'identification des erythrocytes
WO2000071987A2 (en) * 1999-05-25 2000-11-30 John Philip Isolation and culturing of fetal cells
US6692952B1 (en) * 1999-11-10 2004-02-17 Massachusetts Institute Of Technology Cell analysis and sorting apparatus for manipulation of cells
DE10035433C2 (de) * 2000-07-20 2002-07-18 Tuma Wolfgang Schonende Hochanreicherung von fetalen Zellen aus pripherem Blut und Verwendung derselben
AU2002357588B2 (en) * 2001-12-11 2008-11-20 Netech Inc. Blood cell separation system
JP2006501449A (ja) 2002-09-27 2006-01-12 ザ ジェネラル ホスピタル コーポレーション 細胞分離のためのマイクロ流体デバイスおよびその使用
AU2003254755B2 (en) 2002-10-16 2007-12-20 Streck, Inc. Method and device for collecting and preserving cells for analysis
US20040214243A1 (en) * 2003-04-25 2004-10-28 Beckman Coulter, Inc. Differential determination of hemoglobins
US20070160503A1 (en) * 2003-06-13 2007-07-12 Palaniappan Sethu Microfluidic systems for size based removal of red blood cells and platelets from blood
EP1776449A4 (en) * 2004-03-03 2009-08-12 Gen Hospital Corp MAGNETIC DEVICE FOR ISOLATING CELLS AND BIOMOLECULES IN A MICROFLUIDIC ENVIRONMENT
US7653260B2 (en) * 2004-06-17 2010-01-26 Carl Zeis MicroImaging GmbH System and method of registering field of view
US8582924B2 (en) * 2004-06-30 2013-11-12 Carl Zeiss Microimaging Gmbh Data structure of an image storage and retrieval system
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US20070026414A1 (en) * 2005-07-29 2007-02-01 Martin Fuchs Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20070026415A1 (en) * 2005-07-29 2007-02-01 Martin Fuchs Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20070026417A1 (en) * 2005-07-29 2007-02-01 Martin Fuchs Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20070026413A1 (en) * 2005-07-29 2007-02-01 Mehmet Toner Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20070026416A1 (en) * 2005-07-29 2007-02-01 Martin Fuchs Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20090181421A1 (en) * 2005-07-29 2009-07-16 Ravi Kapur Diagnosis of fetal abnormalities using nucleated red blood cells
US20070059680A1 (en) * 2005-09-15 2007-03-15 Ravi Kapur System for cell enrichment
US20070059716A1 (en) * 2005-09-15 2007-03-15 Ulysses Balis Methods for detecting fetal abnormality
US20070059719A1 (en) * 2005-09-15 2007-03-15 Michael Grisham Business methods for prenatal Diagnosis
US20070059718A1 (en) * 2005-09-15 2007-03-15 Mehmet Toner Systems and methods for enrichment of analytes
US20070059781A1 (en) * 2005-09-15 2007-03-15 Ravi Kapur System for size based separation and analysis
US20070059774A1 (en) * 2005-09-15 2007-03-15 Michael Grisham Kits for Prenatal Testing
US20070059683A1 (en) * 2005-09-15 2007-03-15 Tom Barber Veterinary diagnostic system
WO2008143849A2 (en) * 2007-05-14 2008-11-27 Historx, Inc. Compartment segregation by pixel characterization using image data clustering
WO2008156669A1 (en) * 2007-06-15 2008-12-24 Historx, Inc. Method and system for standardizing microscope instruments
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) * 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
WO2009029810A1 (en) * 2007-08-31 2009-03-05 Historx, Inc. Automatic exposure time selection for imaging tissue
WO2009085745A1 (en) * 2007-12-20 2009-07-09 Cytyc Corporation Method for magnetic separation of red blood cells from a patient sample
EP2250497B1 (en) * 2008-02-18 2014-09-10 Genetic Technologies Limited Cell processing and/or enrichment methods
WO2010012002A1 (en) * 2008-07-25 2010-01-28 Saryna Medical Corporation Methods and systems for genetic analysis of fetal nucleated red blood cells
EP2335221B8 (en) * 2008-09-16 2016-05-25 Novartis AG Reproducible quantification of biomarker expression
US20100167271A1 (en) * 2008-12-30 2010-07-01 Streck, Inc. Method for screening blood using a preservative that may be in a substantially solid state form
US11634747B2 (en) * 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
US20100304978A1 (en) * 2009-01-26 2010-12-02 David Xingfei Deng Methods and compositions for identifying a fetal cell
US8231007B2 (en) * 2009-01-29 2012-07-31 Wark Rickey E Static classifier cage
DK2398912T3 (en) 2009-02-18 2017-10-30 Streck Inc Conservation of cell-free nucleic acids
AU2010239131A1 (en) * 2009-04-21 2011-11-17 Genetic Technologies Limited Methods for obtaining fetal genetic material
CN102483406A (zh) * 2009-06-24 2012-05-30 健康公司-拉姆巴姆 用于分离胎盘来源微粒的方法和试剂盒以及它们用于诊断胎儿疾病的应用
EP3103883A1 (en) * 2009-11-09 2016-12-14 Streck, Inc. Stabilization of rna in and extracting from intact cells within a blood sample
CN102762712A (zh) 2010-01-21 2012-10-31 百赛普有限公司 稀有细胞的磁性分离
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
JP5822913B2 (ja) * 2010-04-20 2015-11-25 ヴェンタナ メディカル システムズ, インク. 2色発色性インサイツハイブリダイゼーション
WO2012151391A2 (en) 2011-05-04 2012-11-08 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
ES2676556T3 (es) * 2011-12-23 2018-07-20 Depuy Synthes Products Llc Detección de células derivadas de tejido del cordón umbilical humano
CN104508122A (zh) * 2012-06-20 2015-04-08 赛璐拉有限公司 用于处理细胞群体的材料和方法
EP4008270A1 (en) 2012-06-22 2022-06-08 Preprogen LLC Method for obtaining fetal cells and fetal cellular components
SG10202110062SA (en) * 2012-11-27 2021-11-29 Childrens Medical Center Targeting Bcl11a Distal Regulatory Elements for Fetal Hemoglobin Reinduction
CA2907504C (en) * 2013-03-27 2023-01-17 Theranos, Inc. Methods, devices, and systems for sample analysis
EP3024323B1 (en) 2013-07-24 2022-10-19 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
CN104977284B (zh) * 2015-07-03 2018-05-29 石莹 一种胎儿有核红细胞的捕获及鉴定方法
KR101794218B1 (ko) * 2015-08-19 2017-11-07 인제대학교 산학협력단 비침습적 산전 진단을 위한 산모 혈액 내 유핵 적혈구의 농축 분리 방법
WO2017057076A1 (ja) * 2015-09-28 2017-04-06 富士フイルム株式会社 有核赤血球の取得方法および有核赤血球の識別方法
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
US11506655B2 (en) 2016-07-29 2022-11-22 Streck, Inc. Suspension composition for hematology analysis control
JP6234542B1 (ja) 2016-12-27 2017-11-22 株式会社 TL Genomics 胎児細胞由来染色体dnaの取得方法
US11666915B2 (en) 2017-10-19 2023-06-06 Tl Genomics Inc. Cell classification chip
CN109115584A (zh) * 2018-09-10 2019-01-01 首都医科大学附属北京妇产医院 一种检测红细胞中血红蛋白f的检测试剂及其应用
WO2021009682A1 (en) * 2019-07-15 2021-01-21 Menarini Biomarkers Singapore Pte Ltd Compositions and methods for isolating, detecting, and analyzing fetal cells
CN111948404B (zh) * 2020-08-03 2023-04-07 融智生物科技(青岛)有限公司 用于筛查地中海贫血的特征蛋白标记组合物、质谱模型及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU658132B2 (en) * 1989-11-13 1995-04-06 Children's Medical Center Corporation Non-invasive method for isolation and detection of fetal DNA
BR9306867A (pt) * 1992-07-17 1998-12-08 Aprogenex Inc Enriquecimento e identificação de células fetais do sangue materno para a hibridização in situ
US5457024A (en) * 1993-01-22 1995-10-10 Aprogenex, Inc. Isolation of fetal erythrocytes
WO1995003431A1 (en) * 1993-07-19 1995-02-02 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
US5580724A (en) * 1994-03-25 1996-12-03 Board Of Regents, The University Of Texas System Differential expansion of fetal stem cells in maternal circulation for use in prenatal genetic analysis

Also Published As

Publication number Publication date
AU735380B2 (en) 2001-07-05
CA2269327A1 (en) 1998-04-30
JP2001502805A (ja) 2001-02-27
IL129382A0 (en) 2000-02-17
WO1998018005A1 (en) 1998-04-30
EP1007965B1 (en) 2005-03-02
AU4920097A (en) 1998-05-15
EP1007965A1 (en) 2000-06-14
KR20000052662A (ko) 2000-08-25
DE69732662D1 (de) 2005-04-07
CN1234117A (zh) 1999-11-03
BR9712548A (pt) 1999-12-21
DE69732662T2 (de) 2005-12-29
EP1007965A4 (en) 2000-06-14
ATE290210T1 (de) 2005-03-15
IL129382A (en) 2002-09-12
US5731156A (en) 1998-03-24
RU2178703C2 (ru) 2002-01-27
JP4091123B2 (ja) 2008-05-28
KR100523381B1 (ko) 2005-10-24

Similar Documents

Publication Publication Date Title
HK1031255A1 (en) Use of anti-embryonic hemoglobin antibodies to identify fetal cells
Johnson et al. Fetal cell microchimerism in tissue from multiple sites in women with systemic sclerosis
Bianchi et al. Erythroid‐specific antibodies enhance detection of fetal nucleated erythrocytes in maternal blood
AU2010237203B2 (en) Methods for selecting oocytes and competent embryos with high potential for pregnancy outcome
WO2004087863A2 (en) Non-invasive prenatal genetic diagnosis using transcervical cells
ATE162631T1 (de) Ein nichtinvasives verfahren zur trennung und zum nachweis von fetaler dna
WO2002055985A3 (en) Methods and reagents for identifying rare fetal cells in the material circulation
DE68928535D1 (de) Isolierung von fetalen zellen aus mütterlichem blut zur ausführung von pränataler diagnostik
US20080108071A1 (en) Methods and Systems to Determine Fetal Sex and Detect Fetal Abnormalities
ATE351923T1 (de) Diagnostische methode zur identifizierung von fötaler dna in einer maternalen probe
WO1987003910A1 (en) Cellular method for determining tissue of origin
Zhong et al. Prenatal identification of fetal genetic traits
Mulivor et al. Origin of the alkaline phosphatases in amniotic fluid
MXPA96004278A (es) Expansion diferencial de celulas de baston fetalesen la circulacion materna para usarse en analisisgenetico prenatal.
JP2005506849A5 (xx)
GB2326943B (en) Detection of fetal red cells in maternal blood
Hamada et al. Mid‐trimester fetal sex determination from maternal peripheral blood by fluorescence in situ hybridization without enrichment of fetal cells
Zhang et al. Quantitative abnormalities of fetal trophoblast cells in maternal circulation in preeclampsia
US20060105353A1 (en) Non-invasive prenatal fetal cell diagnostic method
Christensen et al. Fetal cells in maternal blood: a comparison of methods for cell isolation and identification
Sonek et al. Identification of fetal aneuploidy with dual‐probe fluorescence in situ hybridization analysis in circulating trophoblasts after enrichment using a high‐sensitivity microfluidic platform
Tungwiwat et al. Accuracy of fetal gender detection using a conventional nested PCR assay of maternal plasma in daily practice
Abdelhanine et al. Using commercial enzyme immunoassay for measuring pregnancy-associated glycoproteins to diagnose pregnancy in dairy cows under field conditions in Algeria
Fukushima et al. The application of magnetic cell sorter (MACS) to detect fetal cells in maternal peripheral blood
CN118028093A (zh) 一种心肌梗死标志物的检测装置

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20091020