HK1018589A1 - Use of inhibitors of the sodium-hydrogen exchangerfor the production of a pharmaceutical for the tr eatment of disorders which are caused by protozoa - Google Patents

Use of inhibitors of the sodium-hydrogen exchangerfor the production of a pharmaceutical for the tr eatment of disorders which are caused by protozoa

Info

Publication number
HK1018589A1
HK1018589A1 HK99103255A HK99103255A HK1018589A1 HK 1018589 A1 HK1018589 A1 HK 1018589A1 HK 99103255 A HK99103255 A HK 99103255A HK 99103255 A HK99103255 A HK 99103255A HK 1018589 A1 HK1018589 A1 HK 1018589A1
Authority
HK
Hong Kong
Prior art keywords
exchangerfor
eatment
protozoa
disorders
inhibitors
Prior art date
Application number
HK99103255A
Other languages
English (en)
Inventor
Hans Jochen Lang
Michael Lanzer
Jochen Wiesner
Cecilia Sanchez
Stefan Wuensch
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of HK1018589A1 publication Critical patent/HK1018589A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
HK99103255A 1997-08-28 1999-07-28 Use of inhibitors of the sodium-hydrogen exchangerfor the production of a pharmaceutical for the tr eatment of disorders which are caused by protozoa HK1018589A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19737463A DE19737463A1 (de) 1997-08-28 1997-08-28 Verwendung von Inhibitoren des Natrium-Wasserstoff-Austauschers zur Herstellung eines Arzneimittels zur Behandlung von Erkrankungen, die durch Protozoen verursacht werden

Publications (1)

Publication Number Publication Date
HK1018589A1 true HK1018589A1 (en) 1999-12-30

Family

ID=7840411

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99103255A HK1018589A1 (en) 1997-08-28 1999-07-28 Use of inhibitors of the sodium-hydrogen exchangerfor the production of a pharmaceutical for the tr eatment of disorders which are caused by protozoa

Country Status (26)

Country Link
US (1) US6114393A (zh)
EP (1) EP0901788A3 (zh)
JP (1) JPH11171792A (zh)
KR (1) KR100567144B1 (zh)
CN (1) CN1244322C (zh)
AR (1) AR013949A1 (zh)
AU (1) AU738599B2 (zh)
BR (1) BR9803243A (zh)
CA (1) CA2246407A1 (zh)
CZ (1) CZ296815B6 (zh)
DE (1) DE19737463A1 (zh)
HK (1) HK1018589A1 (zh)
HR (1) HRP980468A2 (zh)
HU (1) HU225583B1 (zh)
ID (1) ID20794A (zh)
IL (1) IL125946A0 (zh)
MY (1) MY137406A (zh)
NO (1) NO320368B1 (zh)
NZ (1) NZ331566A (zh)
PL (1) PL191267B1 (zh)
RU (1) RU2225726C2 (zh)
SG (1) SG74074A1 (zh)
SK (1) SK285457B6 (zh)
TR (1) TR199801669A2 (zh)
TW (1) TW592690B (zh)
ZA (1) ZA987781B (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9224739D0 (en) * 1992-11-26 1993-01-13 Wellcome Found Medicaments
MXPA02006328A (es) * 1999-12-23 2002-12-13 Pfizer Prod Inc Forma de dosificacion de farmacos accionada por un hidrogel.
US7375138B2 (en) * 2002-05-18 2008-05-20 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
FR2840302B1 (fr) * 2002-06-03 2004-07-16 Aventis Pharma Sa Derives d'isoindolones, procede de preparation et intermediaire de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
US6878748B2 (en) 2002-06-13 2005-04-12 Aventis Pharma Deutschland Gmbh Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them
CA3069046A1 (en) * 2017-07-04 2019-01-10 Sanofi Ethynyl compounds, their preparation and their therapeutic use for the treatment of malaria

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1336871A (en) * 1970-01-02 1973-11-14 Wellcome Found Method for preparing biologically active substituted amidines
US4032655A (en) * 1974-05-15 1977-06-28 Bayer Aktiengesellschaft Phenylguanidines useful as anthelmintic agents
US4088780A (en) * 1974-05-15 1978-05-09 Bayer Aktiengesellschaft Substituted phenylguanidines and processes for their preparation and use
US4544670A (en) * 1982-08-24 1985-10-01 William H. Rorer, Inc. Method of treating coccidiosis with acyl guanidines
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
IN172842B (zh) * 1990-05-17 1993-12-11 Boots Pharmaceuticals Limited
ATE158589T1 (de) * 1991-11-22 1997-10-15 Yeda Res & Dev Nicht-peptidische surrogate der arg-gly-asp sequenz und entsprechende pharmazeutische zusammensetzungen
CZ284456B6 (cs) * 1992-02-15 1998-12-16 Hoechst Aktiengesellschaft Aminosubstituované benzoylguanidiny, způsob jejich přípravy, jejich použití jako léčiv a léčivo, které je obsahuje
GB9224739D0 (en) * 1992-11-26 1993-01-13 Wellcome Found Medicaments
DE4318658A1 (de) * 1993-06-04 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4318756A1 (de) * 1993-06-05 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19502644A1 (de) * 1995-01-28 1996-08-01 Merck Patent Gmbh 4-Amino-benzoylguanidin-Derivate
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
ES2216049T3 (es) * 1995-06-07 2004-10-16 Genaera Corporation Compuestos de aminosterol utiles como inhibidores del intercambiador de sodio/protones (nhe), metodos y composiciones farmaceuticas que emplean dichos inhibidores y procesos para evaluar la eficacia inhibidora de nhe de dichos compuestos.
DE19542306A1 (de) * 1995-11-14 1997-05-15 Hoechst Ag Sulfonylamino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
RU2225726C2 (ru) 2004-03-20
PL191267B1 (pl) 2006-04-28
CZ272998A3 (cs) 1999-03-17
NO983943D0 (no) 1998-08-27
CZ296815B6 (cs) 2006-06-14
EP0901788A2 (de) 1999-03-17
SK117498A3 (en) 1999-03-12
PL328265A1 (en) 1999-03-01
IL125946A0 (en) 1999-04-11
TR199801669A3 (tr) 1999-03-22
KR19990023905A (ko) 1999-03-25
HUP9801925A3 (en) 2004-11-29
NO320368B1 (no) 2005-11-28
SG74074A1 (en) 2000-07-18
JPH11171792A (ja) 1999-06-29
CN1209994A (zh) 1999-03-10
NZ331566A (en) 2001-03-30
DE19737463A1 (de) 1999-03-04
HU9801925D0 (en) 1998-10-28
CA2246407A1 (en) 1999-02-28
HU225583B1 (en) 2007-03-28
HRP980468A2 (en) 1999-06-30
EP0901788A3 (de) 2004-01-02
TR199801669A2 (xx) 1999-03-22
AU738599B2 (en) 2001-09-20
SK285457B6 (sk) 2007-02-01
ZA987781B (en) 1999-05-27
ID20794A (id) 1999-03-04
KR100567144B1 (ko) 2006-11-30
TW592690B (en) 2004-06-21
AR013949A1 (es) 2001-01-31
US6114393A (en) 2000-09-05
AU8189498A (en) 1999-03-11
HUP9801925A1 (hu) 2000-02-28
MY137406A (en) 2009-01-30
BR9803243A (pt) 2000-03-21
CN1244322C (zh) 2006-03-08
NO983943L (no) 1999-03-01

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090827