ZA9810218B - Isoquinoline derivatives for use against cns disorders - Google Patents

Isoquinoline derivatives for use against cns disorders

Info

Publication number
ZA9810218B
ZA9810218B ZA9810218A ZA9810218A ZA9810218B ZA 9810218 B ZA9810218 B ZA 9810218B ZA 9810218 A ZA9810218 A ZA 9810218A ZA 9810218 A ZA9810218 A ZA 9810218A ZA 9810218 B ZA9810218 B ZA 9810218B
Authority
ZA
South Africa
Prior art keywords
cns disorders
use against
isoquinoline derivatives
against cns
isoquinoline
Prior art date
Application number
ZA9810218A
Inventor
Thierry Godel
Walter Hunkeler
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA9810218B publication Critical patent/ZA9810218B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9810218A 1997-11-10 1998-11-09 Isoquinoline derivatives for use against cns disorders ZA9810218B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97119650 1997-11-10

Publications (1)

Publication Number Publication Date
ZA9810218B true ZA9810218B (en) 1999-05-10

Family

ID=8227597

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9810218A ZA9810218B (en) 1997-11-10 1998-11-09 Isoquinoline derivatives for use against cns disorders

Country Status (4)

Country Link
AR (1) AR016005A1 (en)
AU (1) AU1558899A (en)
WO (1) WO1999024022A2 (en)
ZA (1) ZA9810218B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000069437A1 (en) 1999-05-18 2000-11-23 Synaptic Pharmaceutical Corporation Use of agonists or antagonists of the 5-ht7 receptor to treat disorders of the bladder
EP1676844A1 (en) 2004-12-28 2006-07-05 Laboratorios Del Dr. Esteve, S.A. 5-HT7 receptor antagonists
US7928121B2 (en) 2002-02-19 2011-04-19 Laboratorios Del Dr. Esteve, S.A. 5-HT7 receptor antagonists
AU2003252738A1 (en) * 2002-08-09 2004-02-25 Ajinomoto Co., Inc. Remedy for intestinal diseases and visceral pain
US7553965B2 (en) 2002-11-07 2009-06-30 Laboratories Del Dr. Esteve, S.A. 5-HT7 receptor antagonists
EP1676840A1 (en) 2004-12-28 2006-07-05 Laboratorios Del Dr. Esteve, S.A. 5-HT7 Receptor antagonists
GB0311201D0 (en) 2003-05-15 2003-06-18 Merck Sharp & Dohme Therapeutic agents
CN103788089A (en) 2003-09-17 2014-05-14 詹森药业有限公司 Fused heterocyclic compounds as serotonin receptor modulators
EP1630158A1 (en) 2004-08-18 2006-03-01 Laboratorios Del Dr. Esteve, S.A. 5-HT7 receptor antagonists
US7211584B2 (en) 2004-08-18 2007-05-01 Laboratorios Del Dr. Esteve, S.A. 5-HT7 receptor ligands
ES2257168B1 (en) 2004-08-18 2007-06-01 Laboratorios Del Dr Esteve, S.A. 5-HT7 RECEIVER LIGANDS.
US7211585B2 (en) 2004-08-18 2007-05-01 Laboratorios Del Dr. Esteve, S.A. 5-HT7 receptor antagonists
US7598255B2 (en) 2005-08-04 2009-10-06 Janssen Pharmaceutica Nv Pyrimidine compounds as serotonin receptor modulators
EP2149373A1 (en) 2008-08-01 2010-02-03 Laboratorios Del. Dr. Esteve, S.A. 5HT7 receptor ligands and compositions comprising the same
EP2151777A1 (en) 2008-08-01 2010-02-10 Laboratorios Del. Dr. Esteve, S.A. Method for screening of 5HT7 receptor ligands based on a new pharmacophore model and a descriptor's profile filter
WO2012162814A1 (en) * 2011-06-01 2012-12-06 Mcmaster University Novel antibacterial combination therapy
US8883796B2 (en) 2013-02-08 2014-11-11 Korea Institute Of Science And Technology Biphenyl derivatives, pharmaceutical composition comprising the same, and preparation method thereof
US9663464B2 (en) 2015-02-24 2017-05-30 Korea Institute Of Science And Technology Carbazole derivatives acting on 5-HT7 receptor
WO2017070229A1 (en) 2015-10-19 2017-04-27 Board Of Regents, The University Of Texas System Piperazinyl norbenzomorphan compounds and methods for using the same
US10954217B2 (en) 2016-04-29 2021-03-23 Board Of Regents, The University Of Texas System Sigma receptor binders
KR101917264B1 (en) 2016-12-22 2018-11-13 한국과학기술연구원 Azepine derivaties acting on 5-HT7 receptor ligand

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2426046A1 (en) * 1978-05-18 1979-12-14 Synthelabo TETRAHYDRO-ISOQUINOLEINE DERIVATIVE, ITS PREPARATION AND THERAPEUTIC APPLICATION
US4963563A (en) * 1989-10-13 1990-10-16 Abbott Laboratories 6-substituted-1,2,3,4-tetrahydroisoquinolines
ZA9610738B (en) * 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
JP4117506B2 (en) * 1996-05-01 2008-07-16 エヌピーエス ファーマシューティカルズ インコーポレイテッド Inorganic ion active compound

Also Published As

Publication number Publication date
AU1558899A (en) 1999-05-31
AR016005A1 (en) 2001-05-30
WO1999024022A3 (en) 1999-07-22
WO1999024022A2 (en) 1999-05-20

Similar Documents

Publication Publication Date Title
ZA9810218B (en) Isoquinoline derivatives for use against cns disorders
HRP970478B1 (en) Indazole derivatives
PL339911A1 (en) Transaction effecting apparatus
IL113844A0 (en) Quinoline derivatives
EP0719765A3 (en) Phenylbenzimidazole derivatives
HK1039124B (en) Phthalzaine derivatives phosphodiesterase 4 inhibitors
PL341392A1 (en) Triazinic compounds for treating cns disorders
GB9404378D0 (en) Quinoline derivatives
HUP0003180A3 (en) Phenylethylamine derivatives
GB9402275D0 (en) Quinoline derivatives
SG82014A1 (en) The use of aryl-cyclohexylamine derivatives against cns disorders
GB9413150D0 (en) Quinoline derivatives
HU9700273D0 (en) Tetrahydroisoquinoline derivatives
HU9800889D0 (en) New naphtylpiperazine derivatives
HU9800051V0 (en) Connecting arrangement for tram
GB9403729D0 (en) Amine derivatives
GB2314014B (en) Closure-arrangements for loose-covers
EP0912516A4 (en) Anticonvulsant pyridinyl benzamide derivatives
SI1049672T1 (en) Azetidinecarboxamide derivatives for treating cns disorders
SI1049670T1 (en) Azetidinecarboxamide derivatives for treating cns disorders
IL119852A0 (en) Phenylethylamine derivatives
TW330671U (en) Improved pipe for shower head
IL120509A0 (en) Phenylethylamine derivatives
IL120510A0 (en) Phenylethylamine derivatives
GB9617308D0 (en) Benzamide derivatives