HK1018078A1 - Recombinant sendai virus - Google Patents

Recombinant sendai virus

Info

Publication number
HK1018078A1
HK1018078A1 HK99103083A HK99103083A HK1018078A1 HK 1018078 A1 HK1018078 A1 HK 1018078A1 HK 99103083 A HK99103083 A HK 99103083A HK 99103083 A HK99103083 A HK 99103083A HK 1018078 A1 HK1018078 A1 HK 1018078A1
Authority
HK
Hong Kong
Prior art keywords
sendai virus
recombinant sendai
virus
transfecting
regenerating
Prior art date
Application number
HK99103083A
Other languages
English (en)
Inventor
Yoshiyuki Nagai
Atsushi Kato
Fukashi Murai
Tsuneaki Sakata
Mamoru Hasegawa
Tatsuo Shioda
Original Assignee
Dnavec Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dnavec Research Inc filed Critical Dnavec Research Inc
Publication of HK1018078A1 publication Critical patent/HK1018078A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18811Sendai virus
    • C12N2760/18841Use of virus, viral particle or viral elements as a vector
    • C12N2760/18843Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18811Sendai virus
    • C12N2760/18851Methods of production or purification of viral material
    • C12N2760/18852Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK99103083A 1995-11-01 1999-07-17 Recombinant sendai virus HK1018078A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28541795 1995-11-01
PCT/JP1996/003069 WO1997016539A1 (fr) 1995-11-01 1996-10-22 Virus sendai recombinant

Publications (1)

Publication Number Publication Date
HK1018078A1 true HK1018078A1 (en) 1999-12-10

Family

ID=17691258

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99103083A HK1018078A1 (en) 1995-11-01 1999-07-17 Recombinant sendai virus

Country Status (11)

Country Link
US (2) US7101685B2 (fr)
EP (1) EP0863202B1 (fr)
KR (1) KR100525687B1 (fr)
CN (1) CN1143892C (fr)
AT (1) ATE470704T1 (fr)
AU (1) AU7335296A (fr)
CA (1) CA2236378C (fr)
DE (1) DE69638196D1 (fr)
DK (1) DK0863202T3 (fr)
HK (1) HK1018078A1 (fr)
WO (1) WO1997016539A1 (fr)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7335296A (en) * 1995-11-01 1997-05-22 Dnavec Research Inc. Recombinant sendai virus
ES2313503T3 (es) * 1998-05-18 2009-03-01 Seiko Epson Corporation Aparato de impresion de chorro de tinta y cartucho de tinta para el mismo.
US7241617B2 (en) * 1998-07-03 2007-07-10 Dnavec Research, Inc. Sendai viral vectors comprising foreign genes inserted between the R1 and R2 Loci
KR20010074631A (ko) * 1998-07-03 2001-08-04 가부시끼가이샤 디나벡 겡뀨쇼 신경세포용 (-)쇄 rna 바이러스 벡터
US6828138B1 (en) * 1998-08-11 2004-12-07 Dnavec Research Inc. Recombinant sendai virus vector including a gene encoding a chemokine
US6544785B1 (en) 1998-09-14 2003-04-08 Mount Sinai School Of Medicine Of New York University Helper-free rescue of recombinant negative strand RNA viruses
EP1013667B1 (fr) * 1998-11-09 2006-10-11 Nippon Biologicals, Inc. Procédé de production de cytokines grâce à un système d'expression de virus sendai
US6490775B1 (en) * 1999-04-23 2002-12-10 Veri-Tek Inc. Press operation verification system
US7226786B2 (en) 1999-05-18 2007-06-05 Dnavec Research Inc. Envelope gene-deficient Paramyxovirus vector
US20030166252A1 (en) * 1999-05-18 2003-09-04 Kaio Kitazato Paramyxovirus-derived RNP
WO2000070070A1 (fr) * 1999-05-18 2000-11-23 Dnavec Research Inc. Vecteur de virus paramyxoviridae defectueux dans un gene enveloppe
ES2288866T3 (es) 1999-09-06 2008-02-01 Dnavec Research, Inc. Paramixovirus que contienen una secuencia de inicio de la transcripcion modificada.
US7314614B1 (en) 1999-11-02 2008-01-01 Dnavec Research, Inc. Recombinant sendai virus vector for introducing exogenous genes to airway epithelia
JP4838962B2 (ja) * 1999-11-02 2011-12-14 株式会社ディナベック研究所 気道上皮細胞への外因性遺伝子導入用組換えセンダイウイルスベクター
ATE351915T1 (de) 1999-11-02 2007-02-15 Dnavec Research Inc Rekombinanter sendaivirus-vektor für die einführung von fremdgenen ins epithel der atemwege
CN1418252A (zh) * 2000-01-19 2003-05-14 株式会社载体研究所 副粘病毒属载体在血管内基因转移中的用途
JPWO2001072340A1 (ja) 2000-03-30 2004-01-08 株式会社ディナベック研究所 センダイウイルスベクターを用いたaidsウイルスワクチン
JP2001275684A (ja) * 2000-03-31 2001-10-09 Nippon Medical Research Kk 組換え体イヌジステンパーウイルスおよびその作製方法
CA2322057A1 (fr) 2000-05-18 2001-11-18 Dnavec Research Inc. Paramyxovirus utilises comme vecteurs pour le transfert de genes etrangers
AU2001264824A1 (en) * 2000-06-01 2001-12-11 St. Jude Children's Research Hospital Vaccine and gene therapy vector and methods of use thereof
KR100807016B1 (ko) * 2000-06-01 2008-02-25 가부시키가이샤 디나벡크 겐큐쇼 헤마글루티닌 활성을 갖는 막단백질을 포함하는 슈도타입레트로바이러스 벡터
CA2414077A1 (fr) * 2000-06-27 2002-01-03 Dnavec Research Inc. Vecteur viral pour l'introduction d'un gene dans des cellules renales
WO2002031138A1 (fr) * 2000-10-06 2002-04-18 Dnavec Research Inc. Vecteur de paramyxovirus permettant de transferer un gene etranger dans le muscle squelettique
JP2002142770A (ja) * 2000-11-08 2002-05-21 Dnavec Research Inc 循環系への遺伝子送達用パラミクソウイルスベクター
AU2002224113A1 (en) 2000-11-27 2002-06-03 Dnavec Research Inc. Paramyxovirus vector encoding angiogenesis gene and utilization thereof
US6596206B2 (en) * 2001-03-30 2003-07-22 Picoliter Inc. Generation of pharmaceutical agent particles using focused acoustic energy
CN1678345B (zh) 2002-04-26 2013-09-11 米迪缪尼有限公司 制备流感病毒的多质粒系统
US7465456B2 (en) 2002-04-26 2008-12-16 Medimmune, Llc Multi plasmid system for the production of influenza virus
JPWO2003092738A1 (ja) * 2002-04-30 2005-09-08 株式会社ディナベック研究所 ヘマグルチニン活性を低下させた薬剤または遺伝子運搬組成物
US20050191617A1 (en) * 2002-06-03 2005-09-01 Makoto Inoue Pramyxovirusl vectors encoding antibody and utilization thereof
AU2003261931A1 (en) * 2002-09-04 2004-03-29 Dnavec Research Inc. Process for producing virus vector containing membrane protein having sialic acid-binding activitiy in envelope with the use of gram-positive bacterium-origin neuraminidase
JPWO2004038029A1 (ja) * 2002-10-24 2006-02-23 株式会社ディナベック研究所 T細胞に遺伝子を導入する方法
EP2581093B1 (fr) 2003-06-16 2015-03-18 MedImmune, LLC Hémagglutinine de la grippe et variantes de la neuraminidase
KR20060028432A (ko) * 2003-06-30 2006-03-29 가부시키가이샤 디나벡크 겐큐쇼 고변이영역이 개변된 유전자를 탑재하는 마이너스가닥 rna 바이러스 벡터
KR101279748B1 (ko) * 2003-11-04 2013-07-04 가부시키가이샤 디나벡크 겐큐쇼 유전자 도입된 수상세포의 제조방법
DE602004027537D1 (fr) 2003-12-23 2010-07-15 Medimmune Inc
AU2005205441A1 (en) 2004-01-13 2005-07-28 Dnavec Research Inc. Gene therapy for tumor using minus-strand RNA virus vector encoding immunostimulating cytokine
AU2005206410A1 (en) 2004-01-22 2005-08-04 Dnavec Research Inc. Method of producing minus strand RNA virus vector with the use of hybrid promoter containing cytomegalovirus enhancer and avian beta-actin promoter
JPWO2005071085A1 (ja) * 2004-01-22 2007-09-06 株式会社ディナベック研究所 ウイルスベクターの製造方法
JPWO2005087269A1 (ja) * 2004-03-16 2008-01-24 株式会社ディナベック研究所 腫瘍増殖を抑制する方法
CN1957084A (zh) * 2004-03-23 2007-05-02 株式会社载体研究所 与组织的维持和/或修复相关联的骨髓相关细胞
EP1771552B1 (fr) 2004-05-25 2012-08-01 MedImmune Vaccines, Inc. Variantes d'hémagglutinine influenza et de neuraminidase
JP5296983B2 (ja) * 2004-06-24 2013-09-25 株式会社ディナベック研究所 Rnaウイルスが導入された樹状細胞を含む抗癌剤
DE102005006388A1 (de) * 2005-02-11 2006-08-24 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Replikationsdefiziente RNA-Viren als Impfstoffe
EP2471552B1 (fr) 2005-03-08 2015-05-06 MedImmune, LLC Virus de la grippe réassortis
KR20080016955A (ko) 2005-06-14 2008-02-22 디나벡크 가부시키가이샤 항체의 제작방법
SI1950307T1 (sl) 2005-10-28 2016-02-29 Id Pharma Co., Ltd. Transfer gena v epitelijsko matično celico dihalnih poti z uporabo lentivirusnega vektorja, psevdotipiziranega z RNA virusnim spike proteinom
JPWO2007083644A1 (ja) * 2006-01-17 2009-06-11 ディナベック株式会社 新規タンパク質発現系
CA2654033A1 (fr) 2006-05-31 2007-12-06 Dnavec Corporation Agent therapeutique pour la maladie d'alzheimer
CN101517079A (zh) * 2006-07-13 2009-08-26 生物载体株式会社 非复制型副粘病毒科病毒载体
WO2008133701A1 (fr) 2006-07-21 2008-11-06 Medimmune, Llc. Procédés et compositions permettant d'accroître la capacité de réplication d'un virus de la grippe
KR101559184B1 (ko) 2006-08-09 2015-10-13 메디뮨 엘엘씨 인플루엔자 헤마글루티닌 및 뉴라미니다제 변이체
EP2077326A4 (fr) 2006-09-04 2010-11-10 Kyowa Hakko Kirin Co Ltd Nouvel acide nucléique
EP2415783B1 (fr) 2006-10-16 2016-12-14 Genelux Corporation Souches de virus de vaccin modifiées pour une utilisation pour le diagnostic et procédé thérapeutique
WO2008084319A2 (fr) 2006-12-18 2008-07-17 Kyowa Hakko Kirin Co., Ltd. Nouvel acide nucléique
CN101646768A (zh) 2007-02-07 2010-02-10 生物载体株式会社 减毒负链rna病毒
US9145564B2 (en) * 2007-04-13 2015-09-29 National Institute Of Advanced Industrial Science And Technology Persistently infective Sendai virus vector
US20100203027A1 (en) 2007-04-27 2010-08-12 Kyushu Univeristy National University Viral vector for gene therapy
EP2069484B1 (fr) 2007-06-18 2014-08-13 MedImmune, LLC Virus B de la grippe présentant des modifications du polypeptide de l'hémagglutinine
EP2208499A4 (fr) 2007-10-03 2011-12-28 Kyowa Hakko Kirin Co Ltd Acide nucléique capable de réguler la prolifération d'une cellule
JPWO2009148137A1 (ja) 2008-06-04 2011-11-04 協和発酵キリン株式会社 肥満細胞の脱顆粒を制御する核酸
CA2730408A1 (fr) 2008-07-11 2010-01-14 Chin-Fen Yang Variants de l'hemagglutinine et de la neuraminidase de la grippe
EP2322611B1 (fr) 2008-07-16 2016-06-01 IP Pharma Co., Ltd. Procédé de fabrication d'une cellule reprogrammée utilisant un vecteur viral chromosomiquement non intégré
CN102272302B (zh) 2008-10-31 2015-04-15 生物载体株式会社 增强重组蛋白表达的方法
AU2010213966B2 (en) 2009-02-12 2015-01-22 Medimmune, Llc Influenza hemagglutinin and neuraminidase variants
JP2009268471A (ja) * 2009-08-07 2009-11-19 Dnavec Research Inc センダイウイルスベクターを用いたワクチンおよびワクチンタンパク質
EP2522360B1 (fr) 2010-01-08 2016-11-16 Kyoto University Vaccin pour le traitement de la tauopathie
CN103189508B (zh) 2010-08-30 2016-08-10 生物载体株式会社 用于诱导多能性干细胞的组合物及其用途
CN102205118B (zh) * 2011-03-25 2013-05-22 天津济命生生物科技有限公司 一种生物制品及其制备方法
ES2689797T3 (es) 2011-04-28 2018-11-15 St. Jude Children's Research Vacuna de virus Sendai modificado y vector para la obtención de imágenes
US9951349B2 (en) * 2011-09-27 2018-04-24 Yale University Compositions and methods for transient expression of recombinant RNA
RU2519763C9 (ru) 2012-11-26 2015-04-27 Ольга Вячеславовна Матвеева Метод иммунотерапии онкологических заболеваний и фармацевтические композиции на основе онколитического вируса сендай
AU2014324233B2 (en) 2013-09-24 2020-07-23 Id Pharma Co., Ltd. Method for improving efficiency of inducing pluripotent stem cell
CN110234347A (zh) 2016-11-17 2019-09-13 国立传染病研究所长代表日本国 使用了非感染性副粘病毒粒子的传染病疫苗
WO2019017438A1 (fr) 2017-07-21 2019-01-24 株式会社Idファーマ Polynucléotide destiné à modifier une séquence cible et son utilisation
EP3744847A4 (fr) 2018-01-22 2021-12-08 Japan as Represented by The Director-General of National Institute of Infectious Diseases Antigène vaccinal sélectif induisant les lymphocytes t cd8-positifs
CN112538498B (zh) * 2020-04-20 2023-04-25 梅尔顿(深圳)生物医药技术有限公司 重组仙台病毒的构建方法及其应用
WO2022050419A1 (fr) 2020-09-04 2022-03-10 Heartseed株式会社 Agent améliorant la qualité des cellules ips, procédé de production de cellules ips, cellules ips, et composition pour la production de cellules ips
US20240060051A1 (en) 2020-12-25 2024-02-22 Kyoto University Method for Producing Naive Human IPS Cells From Somatic Cells
WO2023227758A1 (fr) 2022-05-25 2023-11-30 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Vaccin à antigénicité anti-vecteur réduite

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5217879A (en) * 1989-01-12 1993-06-08 Washington University Infectious Sindbis virus vectors
US5166057A (en) * 1989-08-28 1992-11-24 The Mount Sinai School Of Medicine Of The City University Of New York Recombinant negative strand rna virus expression-systems
AU7007491A (en) 1990-02-02 1991-08-08 Schweiz. Serum- & Impfinstitut Bern Cdna corresponding to the genome of negative-strand rna viruses, and process for the production of infectious negative-strand rna viruses
JP3029272B2 (ja) * 1990-05-29 2000-04-04 邦忠 下遠野 構造蛋白質遺伝子、組換えベクター、組換えウイルス、ポリペプチドおよびポリペプチドの製造方法
US5665362A (en) * 1990-09-25 1997-09-09 Cantab Pharmaceuticals Research Limited Viral vaccines
US5173414A (en) * 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5318898A (en) * 1991-04-02 1994-06-07 Genetics Institute, Inc. Production of recombinant bone-inducing proteins
JPH0585943A (ja) * 1991-07-18 1993-04-06 Tonen Corp 組換えワクシニアウイルスを用いる非a非b型肝炎ウイルス遺伝子の発現および非a非b型肝炎ワクチン
US5445953A (en) * 1991-08-26 1995-08-29 Immuno Aktiengesellschaft Direct molecular cloning of a modified poxvirus genome
JPH05301895A (ja) * 1992-04-22 1993-11-16 Nippon Zeon Co Ltd ハイブリッド抗原タンパク質、それを発現する組み換えウイルス、及びその製造方法
ZA937164B (en) 1992-09-28 1994-05-23 Commw Scient Ind Res Org Delivery system
ES2210273T5 (es) * 1994-07-18 2010-03-29 Conzelmann, Karl-Klaus, Prof. Dr. Virus con arn de cadena negativa no segmentado recombinante infeccioso.
US5716821A (en) * 1994-09-30 1998-02-10 Uab Research Foundation Prevention and treatment of respiratory tract disease
US5789229A (en) 1994-09-30 1998-08-04 Uab Research Foundation Stranded RNA virus particles
DE69510207T3 (de) 1995-08-09 2007-02-15 Schweiz. Serum- & Impfinstitut Bern Verfahren zur Herstellung von infektiösen minussträngigen RNA-Viren
EP1325960A3 (fr) * 1995-10-31 2004-09-15 Dnavec Research Inc. Vécteur viral a polarité négative avec capacité de replication autonome
AU7335296A (en) * 1995-11-01 1997-05-22 Dnavec Research Inc. Recombinant sendai virus
CA2253595A1 (fr) 1996-05-01 1997-11-06 The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services Production de transfectants viraux au moyen de proteines nucleocapsidiales derivees d'adn de recombinaison
AT405939B (de) 1997-02-24 1999-12-27 Immuno Ag Verfahren zur inaktivierung von lipidumhüllten viren
US6231868B1 (en) * 1997-09-30 2001-05-15 University Of Maryland-Biotechnology Institute Method for generating nonpathogenic infections birnavirus from synthetic RNA transcripts
US7241617B2 (en) * 1998-07-03 2007-07-10 Dnavec Research, Inc. Sendai viral vectors comprising foreign genes inserted between the R1 and R2 Loci
US6828138B1 (en) 1998-08-11 2004-12-07 Dnavec Research Inc. Recombinant sendai virus vector including a gene encoding a chemokine
EP1013667B1 (fr) * 1998-11-09 2006-10-11 Nippon Biologicals, Inc. Procédé de production de cytokines grâce à un système d'expression de virus sendai
US7226786B2 (en) * 1999-05-18 2007-06-05 Dnavec Research Inc. Envelope gene-deficient Paramyxovirus vector
US20030166252A1 (en) * 1999-05-18 2003-09-04 Kaio Kitazato Paramyxovirus-derived RNP
CN1418252A (zh) * 2000-01-19 2003-05-14 株式会社载体研究所 副粘病毒属载体在血管内基因转移中的用途
JPWO2001072340A1 (ja) * 2000-03-30 2004-01-08 株式会社ディナベック研究所 センダイウイルスベクターを用いたaidsウイルスワクチン
CA2322057A1 (fr) * 2000-05-18 2001-11-18 Dnavec Research Inc. Paramyxovirus utilises comme vecteurs pour le transfert de genes etrangers
CA2414077A1 (fr) * 2000-06-27 2002-01-03 Dnavec Research Inc. Vecteur viral pour l'introduction d'un gene dans des cellules renales
WO2002031138A1 (fr) * 2000-10-06 2002-04-18 Dnavec Research Inc. Vecteur de paramyxovirus permettant de transferer un gene etranger dans le muscle squelettique
AU2002224113A1 (en) * 2000-11-27 2002-06-03 Dnavec Research Inc. Paramyxovirus vector encoding angiogenesis gene and utilization thereof
JPWO2004038029A1 (ja) 2002-10-24 2006-02-23 株式会社ディナベック研究所 T細胞に遺伝子を導入する方法
WO2004067752A1 (fr) 2003-01-31 2004-08-12 Dnavec Research Inc. Vecteur de papimyvirus codant pour un ribozyme et son utilisation
KR20060028432A (ko) * 2003-06-30 2006-03-29 가부시키가이샤 디나벡크 겐큐쇼 고변이영역이 개변된 유전자를 탑재하는 마이너스가닥 rna 바이러스 벡터
KR101279748B1 (ko) 2003-11-04 2013-07-04 가부시키가이샤 디나벡크 겐큐쇼 유전자 도입된 수상세포의 제조방법
AU2005205441A1 (en) * 2004-01-13 2005-07-28 Dnavec Research Inc. Gene therapy for tumor using minus-strand RNA virus vector encoding immunostimulating cytokine
JPWO2005071085A1 (ja) * 2004-01-22 2007-09-06 株式会社ディナベック研究所 ウイルスベクターの製造方法
AU2005206410A1 (en) * 2004-01-22 2005-08-04 Dnavec Research Inc. Method of producing minus strand RNA virus vector with the use of hybrid promoter containing cytomegalovirus enhancer and avian beta-actin promoter
CN1957084A (zh) * 2004-03-23 2007-05-02 株式会社载体研究所 与组织的维持和/或修复相关联的骨髓相关细胞
JP5296983B2 (ja) * 2004-06-24 2013-09-25 株式会社ディナベック研究所 Rnaウイルスが導入された樹状細胞を含む抗癌剤

Also Published As

Publication number Publication date
DE69638196D1 (de) 2010-07-22
KR19990067271A (ko) 1999-08-16
US7442544B2 (en) 2008-10-28
CN1143892C (zh) 2004-03-31
KR100525687B1 (ko) 2005-11-25
EP0863202B1 (fr) 2010-06-09
US20020098576A1 (en) 2002-07-25
CA2236378A1 (fr) 1997-05-09
ATE470704T1 (de) 2010-06-15
EP0863202A4 (fr) 1999-03-03
CA2236378C (fr) 2011-01-25
WO1997016539A1 (fr) 1997-05-09
US20050266566A1 (en) 2005-12-01
US7101685B2 (en) 2006-09-05
CN1207124A (zh) 1999-02-03
AU7335296A (en) 1997-05-22
DK0863202T3 (da) 2010-09-27
EP0863202A1 (fr) 1998-09-09

Similar Documents

Publication Publication Date Title
HK1018078A1 (en) Recombinant sendai virus
HK1018287A1 (en) (-)-strand rna virus vector having autonomously replicating activity
WO1996013597A3 (fr) Adenovirus recombine et ses procedes d'utilisation
EP1312679B8 (fr) Virus MVA recombinants et leur utilisation
PL333070A1 (en) Infectious clones of rna viruses and vaccines based on them
CA2104396A1 (fr) Particules virales ayant une specificite d'hote modifiee
ATE411818T1 (de) Rekombinantes,virales vektorsystem
WO1997005255A3 (fr) Virus auxiliaires pour la preparation de vecteurs viraux recombinants
BR9711998A (pt) Herpesvìrus saimiri como vetor viral.
WO1994013812A3 (fr) Nouveaux genes de l'entomopoxvirus, nouvelles proteines et leurs procedes d'utilisation
CA2037677A1 (fr) Methode de production d'un gene exogene ou son produit dans les cellules vegetales
JO1885B1 (en) A method for purifying surface serum for viral hepatitis B, consisting of Bryce 2 peptide
WO2003025187A8 (fr) Expression genique amelioree a l'aide de vecteurs
AU5958694A (en) Synthetic herpes simplex virus promoters
DE69839269D1 (de) Infektiöse vektoren und pflanzenklone, die sich von turnip mosaikvirus herleiten
FI98466B (fi) FSME-viruksen läntisen alatyypin eristettyjä DNA- ja RNA-molekyylejä, näitä sisältäviä vektoreita ja soluviljelmiä sekä menetelmä näiden koodittamien peptidien valmistamiseksi
ES8703519A1 (es) Procedimiento para la formacion de hibridos celulares

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20141022