HK1014946A1 - Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings - Google Patents

Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings

Info

Publication number
HK1014946A1
HK1014946A1 HK99100058A HK99100058A HK1014946A1 HK 1014946 A1 HK1014946 A1 HK 1014946A1 HK 99100058 A HK99100058 A HK 99100058A HK 99100058 A HK99100058 A HK 99100058A HK 1014946 A1 HK1014946 A1 HK 1014946A1
Authority
HK
Hong Kong
Prior art keywords
alkyl
halo
aryl
methyl
phenyloxazolidinones
Prior art date
Application number
HK99100058A
Other languages
English (en)
Inventor
Douglas K Hutchinson
Michael D Ennis
Robert L Hoffman
Richard C Thomas
Toni-Jo Poel
Michael Robert Barbachyn
Steven J Brickner
David J Anderson
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21704418&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1014946(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of HK1014946A1 publication Critical patent/HK1014946A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
HK99100058A 1995-09-01 1999-01-07 Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings HK1014946A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US314995P 1995-09-01 1995-09-01
PCT/US1996/012766 WO1997009328A1 (en) 1995-09-01 1996-08-13 Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings

Publications (1)

Publication Number Publication Date
HK1014946A1 true HK1014946A1 (en) 1999-10-08

Family

ID=21704418

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99100058A HK1014946A1 (en) 1995-09-01 1999-01-07 Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings

Country Status (27)

Country Link
US (7) US5968962A (ru)
EP (1) EP0856002B1 (ru)
JP (1) JPH11512386A (ru)
KR (1) KR100463772B1 (ru)
CN (1) CN1072222C (ru)
AT (1) ATE207487T1 (ru)
AU (1) AU716493B2 (ru)
BR (1) BR9610474A (ru)
CA (1) CA2228647A1 (ru)
CZ (1) CZ49398A3 (ru)
DE (1) DE69616366T2 (ru)
DK (1) DK0856002T3 (ru)
ES (1) ES2165516T3 (ru)
FI (1) FI980452A (ru)
HK (1) HK1014946A1 (ru)
HU (1) HUP9901979A3 (ru)
MX (1) MX9801578A (ru)
NO (1) NO311520B1 (ru)
NZ (1) NZ315469A (ru)
PL (1) PL186524B1 (ru)
PT (1) PT856002E (ru)
RU (1) RU2175324C2 (ru)
SK (1) SK283487B6 (ru)
TW (1) TW419468B (ru)
UA (1) UA52620C2 (ru)
WO (1) WO1997009328A1 (ru)
ZA (1) ZA966935B (ru)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997009328A1 (en) * 1995-09-01 1997-03-13 Pharmacia & Upjohn Company Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
CN1211384C (zh) * 1997-07-11 2005-07-20 法玛西雅厄普约翰美国公司 噻二唑基和噁二唑基苯基噁唑烷酮抗菌剂
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
US6083967A (en) * 1997-12-05 2000-07-04 Pharmacia & Upjohn Company S-oxide and S,S-dioxide tetrahydrothiopyran phenyloxazolidinones
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
AU764184B2 (en) 1998-01-23 2003-08-14 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
CN1311787A (zh) * 1998-06-05 2001-09-05 阿斯特拉曾尼卡有限公司 噁唑烷酮衍生物、其制备方法以及含有它们的药物组合物
CN1142158C (zh) 1999-02-01 2004-03-17 法玛西雅厄普约翰美国公司 制备环状含硫氟的噁唑烷酮的方法
SI1149089T1 (en) * 1999-02-01 2003-10-31 Pharmacia & Upjohn Company PROCESS TO PREPARE TETRAHYDROTHIOPYRAN-o-FLUORINATED CARBAMATES
MY120189A (en) 1999-11-04 2005-09-30 Upjohn Co Sultam and sultone derived oxazolidinones
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
HUP0203869A2 (hu) * 1999-12-21 2003-07-28 Pharmacia & Upjohn Co. Szulfoximin funkcionalitással rendelkező oxazolidinok és alkalmazásuk mikrobaellenes szerként, a vegyületeket tartalmazó gyógyszerkészítmények
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
MY127336A (en) 2000-03-22 2006-11-30 Upjohn Co Container for linezolid iv solution
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
PE20020044A1 (es) 2000-06-16 2002-01-30 Upjohn Co Tiazina oxazolidinona
DK1301207T3 (da) 2000-06-30 2005-10-10 Pharmacia & Upjohn Co Llc Sammensætninger til behandling af bakterieinfektioner indeholdende en oxazolidinonforbindelse, sulbactam og ampicillin
GB0108764D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
DE60212959T2 (de) * 2001-04-07 2007-02-15 Astrazeneca Ab Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika
ATE374463T1 (de) * 2001-04-20 2007-10-15 Pharmacia & Upjohn Co Llc Verfahren zur herstellung von oxazolidinonen
MXPA03009643A (es) 2001-04-20 2004-05-21 Upjohn Co Un metodo para la preparacion de oxazolidinonas.
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
EP1451164A2 (en) * 2001-07-12 2004-09-01 PHARMACIA & UPJOHN COMPANY Amide derivatives having improved solubility
US7125568B2 (en) * 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
BR0307103A (pt) * 2002-01-24 2004-12-28 Upjohn Co Dihidrotiazina e dihidrotiopirano oxazolidinovas antimicrobianas
TW200302095A (en) * 2002-01-25 2003-08-01 Upjohn Co Oxazolidinone cotherapy
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
BR0308806A (pt) * 2002-03-29 2005-01-04 Upjohn Co Uso de oxazolidinonas para tratar infecções do tipo pé diabético
WO2003097640A1 (en) * 2002-05-22 2003-11-27 Orchid Chemicals & Pharmaceuticals Ltd. Oxazolidinone derivatives as antibacterial agents
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
TW200404069A (en) * 2002-06-28 2004-03-16 Upjohn Co Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent
CA2491287A1 (en) * 2002-08-12 2004-02-19 Pharmacia & Upjohn Company N-aryl-2-oxazolidinones and their derivatives
ES2271660T3 (es) * 2002-11-21 2007-04-16 PHARMACIA & UPJOHN COMPANY LLC Derivados de n-(4-piperazin-1-il)-fenil-2-oxazolidinona-5-carboxamida y compuestos relacionados como agentes antibacterianos.
DE10300111A1 (de) 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
WO2004069244A1 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Oxazolidinone derivatives n-substituted by a bicyclic ring, for use as antibacterial agents
EP1594865A2 (en) * 2003-02-07 2005-11-16 Warner-Lambert Company LLC Antibacterial agents
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
EP1625124A1 (en) * 2003-05-06 2006-02-15 Ranbaxy Laboratories, Ltd. Oxazolidinone derivatives as antimicrobials
WO2004113329A1 (en) * 2003-06-20 2004-12-29 Orchid Chemicals And Pharmaceuticals Ltd. Oxazole derivatives as antibacterial agents
US7304050B2 (en) 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
US7265140B2 (en) 2003-09-23 2007-09-04 Pfizer Inc Acyloxymethylcarbamate prodrugs of oxazolidinones
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
WO2005082892A2 (en) * 2004-02-17 2005-09-09 Dr. Reddy's Laboratories Ltd. Triazole compounds as antibacterial agents and pharmaceutical compositions containing them
JP2008509126A (ja) * 2004-08-06 2008-03-27 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 抗菌剤としてオキシインドールを含有するオキサゾリジノン類
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
DE102005045518A1 (de) 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
PL1934208T3 (pl) 2005-10-04 2011-09-30 Bayer Ip Gmbh Nowa polimorficzna postać 5-chloro-N-({ (5S)-2-okso-3-[4-( 3-okso-4-morfolinylo)-fenylo]-1,3-oksazolidyn-5-ylo}-metylo)-2-tiofenokarboksamidu
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
CN103497173A (zh) 2006-03-31 2014-01-08 财团法人乙卯研究所 具有杂环的新化合物
WO2008039534A2 (en) * 2006-09-27 2008-04-03 Amberwave Systems Corporation Quantum tunneling devices and circuits with lattice- mismatched semiconductor structures
WO2008143649A2 (en) * 2006-12-04 2008-11-27 Dr. Reddy's Laboratories Limited Novel oxazolidinone compounds as antiinfective agents
US7978614B2 (en) * 2007-01-11 2011-07-12 Foundry Network, LLC Techniques for detecting non-receipt of fault detection protocol packets
CL2008001003A1 (es) * 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
WO2009044777A1 (ja) 2007-10-02 2009-04-09 Research Foundation Itsuu Laboratory ７員ヘテロ環を有するオキサゾリジノン誘導体
KR101023174B1 (ko) * 2008-09-24 2011-03-18 주식회사 레고켐 바이오사이언스 사이클릭 아미독심 또는 사이클릭 아미드라존 기를 가지는 신규한 옥사졸리디논 유도체 및 이를 함유하는 의약 조성물
CA2743971A1 (en) 2008-11-20 2010-05-27 Panacea Biotec Ltd. Novel antimicrobials
AU2011300365A1 (en) * 2010-09-07 2013-05-02 Symed Labs Limited Processes for the preparation of 4-{4-[5(S)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl} morpholin-3-one
AR093396A1 (es) * 2012-11-09 2015-06-03 Syngenta Participations Ag Derivados de dihidrotiofeno como compuestos insecticidas
WO2020147504A1 (en) * 2019-01-18 2020-07-23 Merck Sharp & Dohme Corp. Oxazolidinone compounds and methods of use thereof as antibacterial agents
CA3217423A1 (en) 2021-06-16 2022-12-22 Jeffrey M. Schkeryantz Azetidinyl compounds comprising a carboxylic acid group for the treatment of neurodegenerative diseases
CN115724823B (zh) * 2021-08-27 2023-11-24 中国科学院大连化学物理研究所 一种制备二氢噻吩衍生物的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1252101A (ru) * 1969-03-18 1971-11-03
FR2356422A1 (fr) * 1976-03-01 1978-01-27 Delalande Sa Nouveaux hydroxymethyl-5 oxazolidinone-2, leur procede de preparation et leur application en therapeutique
FR2380780A2 (fr) * 1977-02-22 1978-09-15 Delalande Sa Application en therapeutique des hydroxymethyl-5 oxazolidinones-2, notamment comme antidepresseurs
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
JPS59118721A (ja) * 1982-12-25 1984-07-09 Nippon Zeon Co Ltd カルボキシル化合物の製造方法
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
DE3544601A1 (de) * 1984-12-18 1986-06-19 C.S. Kaseihin Co. Inc., Tokio/Tokyo Verfahren zur herstellung von siliciumhaltigen isocyanatverbindungen
US5130316A (en) * 1988-07-29 1992-07-14 Du Pont Merck Pharmaceutical Company Aminomethyloxooxazlidinyl arylbenzene derivatives useful as antibacterial agents
US5254577A (en) * 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
EP0610265B1 (en) * 1991-11-01 1996-12-27 PHARMACIA & UPJOHN COMPANY Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5668286A (en) * 1994-03-15 1997-09-16 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions containing them
DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
WO1997009328A1 (en) * 1995-09-01 1997-03-13 Pharmacia & Upjohn Company Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
EP0984947B8 (en) * 1997-05-30 2005-06-15 Pharmacia & Upjohn Company LLC Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9717807D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
CN1142158C (zh) * 1999-02-01 2004-03-17 法玛西雅厄普约翰美国公司 制备环状含硫氟的噁唑烷酮的方法
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents

Also Published As

Publication number Publication date
SK283487B6 (sk) 2003-08-05
TW419468B (en) 2001-01-21
WO1997009328A1 (en) 1997-03-13
EP0856002A1 (en) 1998-08-05
FI980452A0 (fi) 1998-02-27
PL186524B1 (pl) 2004-01-30
NO980855L (no) 1998-04-30
DE69616366D1 (de) 2001-11-29
US20050054683A1 (en) 2005-03-10
AU716493B2 (en) 2000-02-24
JPH11512386A (ja) 1999-10-26
US6043266A (en) 2000-03-28
DE69616366T2 (de) 2002-07-04
CN1197457A (zh) 1998-10-28
HUP9901979A3 (en) 2000-03-28
PT856002E (pt) 2002-04-29
US6051716A (en) 2000-04-18
US6358942B1 (en) 2002-03-19
CZ49398A3 (cs) 1998-08-12
CN1072222C (zh) 2001-10-03
MX9801578A (es) 1998-08-30
BR9610474A (pt) 1999-03-02
US5968962A (en) 1999-10-19
UA52620C2 (ru) 2003-01-15
SK19598A3 (en) 1998-11-04
CA2228647A1 (en) 1997-03-13
EP0856002B1 (en) 2001-10-24
KR100463772B1 (ko) 2005-11-09
ZA966935B (en) 1998-02-16
NO980855D0 (no) 1998-02-27
RU2175324C2 (ru) 2001-10-27
AU6718196A (en) 1997-03-27
NO311520B1 (no) 2001-12-03
FI980452A (fi) 1998-02-27
DK0856002T3 (da) 2002-02-11
ES2165516T3 (es) 2002-03-16
NZ315469A (en) 2000-01-28
US6166056A (en) 2000-12-26
US6313307B1 (en) 2001-11-06
PL325152A1 (en) 1998-07-06
KR19990044238A (ko) 1999-06-25
HUP9901979A2 (hu) 2000-02-28
ATE207487T1 (de) 2001-11-15

Similar Documents

Publication Publication Date Title
HK1014946A1 (en) Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings
NO20011479D0 (no) Nye amidderivater, fremstilling derav og anvendelse som medikamenter og farmasøytiske sammensetninger inneholdende disse
AU636012B2 (en) N-(4-piperidinyl)(dihydrobenzofuran or dihydro-2h-benzopyran )carboxamide derivatives
HUT62280A (en) Process for producing benzofuran, benzothiophene, indole and indolizine derivatives and pharmaceutical compositions comprising same
IL116387A0 (en) Use of 5-acyl-1,4-dihydropyridines
ATE187714T1 (de) 2-cyano-3,5-dihydroxy-hex-2-en-carbonsäure- amidderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20060813