HK1007442A1 - Electrochemiluminescent assays - Google Patents

Electrochemiluminescent assays

Info

Publication number
HK1007442A1
HK1007442A1 HK98106428A HK98106428A HK1007442A1 HK 1007442 A1 HK1007442 A1 HK 1007442A1 HK 98106428 A HK98106428 A HK 98106428A HK 98106428 A HK98106428 A HK 98106428A HK 1007442 A1 HK1007442 A1 HK 1007442A1
Authority
HK
Hong Kong
Prior art keywords
electrochemiluminescent
analyte
different
same
electrochemiluminescent assays
Prior art date
Application number
HK98106428A
Other languages
English (en)
Inventor
Richard J Massey
Michael J Powell
Paul A Mied
Peter Feng
Leopoldo Della Ciana
Walter J Dressick
Mohindar S Poonian
Original Assignee
Igen Int Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Igen Int Inc filed Critical Igen Int Inc
Publication of HK1007442A1 publication Critical patent/HK1007442A1/xx

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/002Osmium compounds
    • C07F15/0026Osmium compounds without a metal-carbon linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046Ruthenium compounds
    • C07F15/0053Ruthenium compounds without a metal-carbon linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/30Electrochemically active labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Reproductive Health (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Luminescent Compositions (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
HK98106428A 1986-04-30 1998-06-24 Electrochemiluminescent assays HK1007442A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85835486A 1986-04-30 1986-04-30

Publications (1)

Publication Number Publication Date
HK1007442A1 true HK1007442A1 (en) 1999-04-09

Family

ID=25328109

Family Applications (2)

Application Number Title Priority Date Filing Date
HK98106428A HK1007442A1 (en) 1986-04-30 1998-06-24 Electrochemiluminescent assays
HK98115071A HK1013653A1 (en) 1986-04-30 1998-12-23 Electroluminescent compounds and intermediates in their synthesis

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK98115071A HK1013653A1 (en) 1986-04-30 1998-12-23 Electroluminescent compounds and intermediates in their synthesis

Country Status (13)

Country Link
EP (3) EP0265519B1 (fr)
JP (6) JPH0737464B2 (fr)
KR (1) KR960016340B1 (fr)
AT (2) ATE212030T1 (fr)
AU (2) AU644150B2 (fr)
CA (1) CA1339465C (fr)
DE (2) DE3751516T2 (fr)
DK (1) DK173025B1 (fr)
FI (1) FI102017B (fr)
HK (2) HK1007442A1 (fr)
IL (1) IL82411A0 (fr)
NO (1) NO176071C (fr)
WO (1) WO1987006706A1 (fr)

Families Citing this family (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635347A (en) * 1986-04-30 1997-06-03 Igen, Inc. Rapid assays for amplification products
US6271041B1 (en) * 1986-04-30 2001-08-07 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US6451225B1 (en) 1986-04-30 2002-09-17 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US6165729A (en) * 1986-04-30 2000-12-26 Hyperion Catalysis International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US6881536B1 (en) * 1986-04-30 2005-04-19 Bioveris Corporation Particle based electrochemiluminescent assays
US5770459A (en) * 1986-04-30 1998-06-23 Igen International, Inc. Methods and apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence detection
US6881589B1 (en) 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
US5935779A (en) * 1988-11-03 1999-08-10 Igen International Inc. Methods for improved particle electrochemiluminescence assay
US6702986B1 (en) 1988-04-29 2004-03-09 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US5746974A (en) * 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
US5705402A (en) * 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
EP0441894B1 (fr) * 1988-11-03 1997-12-10 Igen, Inc. Reaction electrochimioluminescente utilisant un reducteur derive d'une amine
WO1990005301A1 (fr) * 1988-11-03 1990-05-17 Igen, Inc. Analyses electrochimioluminescentes
US5962218A (en) * 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
JPH0363571A (ja) * 1989-08-02 1991-03-19 Chisso Corp 大腸菌群の検査キット
IL100867A (en) * 1991-02-06 1995-12-08 Igen Inc Method and device for improved luminescence testing
IL100866A (en) * 1991-02-06 1995-10-31 Igen Inc Luminescence test method and device based on magnetic tiny particles, containing many magnets
ZA92803B (en) 1991-02-06 1992-11-25 Igen Inc Method and apparatus for magnetic microparticulate based luminescene asay including plurality of magnets
ATE184320T1 (de) * 1991-07-10 1999-09-15 Igen Int Inc Verfahren für verbesserte lumineszenz-assays unter verwendung von teilchenkonzentration und chemilumineszenznachweis
DK0567635T3 (da) * 1991-11-15 2000-09-25 Igen Int Inc Hurtige assays for amplifikationsprodukter
ZA929351B (en) * 1991-12-11 1993-06-04 Igen Inc Electrochemiluminescent label for DNA assays.
FR2699170B1 (fr) * 1992-12-15 1995-07-28 Asulab Sa Complexes d'un métal de transition à ligands 2,2'-bipyridine substitués par au moins un radical ammonium alkyle, leur procédé de fabrication et leur application comme médiateur redox.
US5541113A (en) * 1993-09-22 1996-07-30 Beckman Instruments, Inc. Method for detecting an analyte using an electrochemical luminescent transition metal label
DE59507438D1 (de) * 1994-07-25 2000-01-20 Roche Diagnostics Gmbh Hydrophile metallkomplexe
CA2704228C (fr) * 1995-03-10 2013-10-22 Meso Scale Technologies, Llc Essai par electrochimioluminescence multispecifique et multirangee
US6319670B1 (en) 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
WO1996041175A1 (fr) 1995-06-07 1996-12-19 Igen, Inc. Dosage immunologique d'enzymes par electrochimioluminescence
EP0791821A4 (fr) * 1995-09-12 1999-10-27 Eisai Co Ltd Procede et appareil de detection d'electrochemiluminescence
US7885697B2 (en) 2004-07-13 2011-02-08 Dexcom, Inc. Transcutaneous analyte sensor
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US6862465B2 (en) 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US6613583B1 (en) 1997-06-27 2003-09-02 Igen International, Inc. Electrochemiluminescent label based on multimetallic assemblies
DE19803528A1 (de) * 1998-01-30 1999-08-05 Roche Diagnostics Gmbh Verfahren zur Analyse einer Probe mittels eines Elektrochemolumineszenz-Bindungsreaktion-Tests
DE19811582A1 (de) * 1998-03-17 1999-09-23 Roche Diagnostics Gmbh Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen
DE19828441A1 (de) * 1998-06-25 1999-12-30 Roche Diagnostics Gmbh Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
US6214552B1 (en) 1998-09-17 2001-04-10 Igen International, Inc. Assays for measuring nucleic acid damaging activities
US6312896B1 (en) 1998-09-17 2001-11-06 Igen Inaternational, Inc. Assays for measuring nucleic acid binding proteins and enzyme activities
US7041807B1 (en) 1999-06-23 2006-05-09 Caprion Pharmaceuticals, Inc. Antibodies to a YYX epitope of a mammalian prion protein
CA2451789C (fr) 2001-06-29 2012-03-27 Meso Scale Technologies, Llc. Plaques d'epreuve, systemes lecteurs et methodes de mesures de tests par luminescence
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
EP3021106B8 (fr) 2001-07-30 2019-03-27 Meso Scale Technologies, LLC Procédés d'utilisation d'un électrode de test dotée de couches de lipides/protéines immobilisées pour des mesures de test de luminescence
EP1436598B1 (fr) 2001-09-10 2013-11-27 Meso Scale Technologies LLC Tampon de dosage, compositions contenant ce tampon et procedes d'utilisation correspondants
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
US20040072236A1 (en) 2002-09-27 2004-04-15 Neil Cashman PrPSc -interacting molecules and uses thereof
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
US7715893B2 (en) 2003-12-05 2010-05-11 Dexcom, Inc. Calibration techniques for a continuous analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US8060173B2 (en) 2003-08-01 2011-11-15 Dexcom, Inc. System and methods for processing analyte sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US7519408B2 (en) 2003-11-19 2009-04-14 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US20100168543A1 (en) 2003-08-01 2010-07-01 Dexcom, Inc. System and methods for processing analyte sensor data
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
US7955261B2 (en) 2003-08-01 2011-06-07 Dexcom, Inc. System and methods for processing analyte sensor data
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US8233959B2 (en) 2003-08-22 2012-07-31 Dexcom, Inc. Systems and methods for processing analyte sensor data
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8774886B2 (en) 2006-10-04 2014-07-08 Dexcom, Inc. Analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP2316331B1 (fr) 2003-12-09 2016-06-29 Dexcom, Inc. Traitement de signal pour capteur d'analyte continu
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
ITTO20040372A1 (it) * 2004-06-01 2004-09-01 Giuseppe Caputo Composti luminescenti aventi un braccio di legame funzionalizzato.
CN101057145B (zh) 2004-06-23 2014-10-22 得克萨斯系统大学评议会 使用双粒子复合体检测生物分子的方法和组合物
US7640048B2 (en) 2004-07-13 2009-12-29 Dexcom, Inc. Analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US20060270922A1 (en) 2004-07-13 2006-11-30 Brauker James H Analyte sensor
WO2006038686A1 (fr) * 2004-10-07 2006-04-13 Matsushita Electric Industrial Co., Ltd. Procédé de détection de gène et appareil de détection de gène
EP1893990B1 (fr) 2005-06-03 2018-05-02 Board of Regents of the University of Texas System Electrochimie et chimioluminescence electrogeneree avec une electrode faradique unique
WO2007055302A1 (fr) * 2005-11-10 2007-05-18 National University Corporation University Of Toyama Procede d'evaluation des proprietes de liaison entre un biomateriau et un materiau de liaison de biomateriaux
US20080306434A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
EP4098177A1 (fr) 2007-10-09 2022-12-07 DexCom, Inc. Système d'administration d'insuline intégré avec un capteur de glucose en continu
EP2217608B1 (fr) * 2007-11-21 2012-09-05 Bio-Rad Laboratories, Inc. Complexes de métaux photoluminescents pour une coloration de protéines
CA2715628A1 (fr) 2008-02-21 2009-08-27 Dexcom, Inc. Systemes et procedes pour traiter, transmettre et afficher des donnees de detecteur
DK2271938T3 (da) 2008-04-11 2014-05-12 Univ Texas Fremgangsmåde og apparat til nanopartikel-elektrogenereret kemiluminescens-amplifikation
AU2009244904B2 (en) * 2008-05-08 2014-04-17 Board Of Regents Of The University Of Texas System Luminescent nanostructured materials for use in electrogenerated chemiluminescence
AU2014203680B2 (en) * 2008-05-08 2015-03-05 Board Of Regents Of The University Of Texas System Luminescent nanostructured materials for use in electrogenerated chemiluminescence
US8264347B2 (en) 2008-06-24 2012-09-11 Trelleborg Sealing Solutions Us, Inc. Seal system in situ lifetime measurement
FR2939895B1 (fr) * 2008-12-15 2011-01-14 Commissariat Energie Atomique Procede de detection non intrusive d'element chimique
EP3925533B1 (fr) 2009-04-30 2024-04-10 DexCom, Inc. Rapports de performances associés à des données de détecteur continues à partir de périodes multiples de temps d'analyse
WO2012005588A2 (fr) 2010-07-07 2012-01-12 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg Nouveaux biomarqueurs pour détecter la perte neuronale
WO2012107420A1 (fr) * 2011-02-09 2012-08-16 Roche Diagnostics Gmbh Nouveaux complexes à base d'iridium pour électrochimiluminescence
US20120265036A1 (en) 2011-04-15 2012-10-18 Dexcom, Inc. Advanced analyte sensor calibration and error detection
MX347611B (es) 2011-06-19 2017-05-04 Abogen Inc Dispositivos, soluciones y metodos para recoleccion de muestras.
AU2012280022A1 (en) * 2011-07-07 2014-01-09 Dupont Nutrition Biosciences Aps Assay
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US9075042B2 (en) 2012-05-15 2015-07-07 Wellstat Diagnostics, Llc Diagnostic systems and cartridges
CA2879093C (fr) 2012-08-02 2020-10-20 F. Hoffmann-La Roche Ag Complexes bis-iridium pour la fabrication d'etiquettes-livrets
US9481903B2 (en) 2013-03-13 2016-11-01 Roche Molecular Systems, Inc. Systems and methods for detection of cells using engineered transduction particles
EP3699592A1 (fr) 2013-03-13 2020-08-26 Geneweave Biosciences Inc. Particules de transduction non réplicative et systèmes de rapporteur basé sur des particules de transduction
US9540675B2 (en) 2013-10-29 2017-01-10 GeneWeave Biosciences, Inc. Reagent cartridge and methods for detection of cells
CA2947704A1 (fr) * 2014-04-10 2015-10-15 Dna Genotek Inc. Procede et systeme pour la lyse microbienne a l'aide de periodates
EP3230739B1 (fr) 2014-12-08 2019-01-23 F.Hoffmann-La Roche Ag Procédé de mesure de la vitamine d
TR201909273T4 (tr) 2015-08-20 2019-07-22 Hoffmann La Roche Bir pegile analit spesifik bağlanma ajanının kullanıldığı partikül bazlı immünolojik test.
US10351893B2 (en) 2015-10-05 2019-07-16 GeneWeave Biosciences, Inc. Reagent cartridge for detection of cells
KR102437995B1 (ko) 2016-03-07 2022-08-29 에프. 호프만-라 로슈 아게 항-p53 항체의 검출
JP7039481B2 (ja) 2016-03-11 2022-03-22 エフ.ホフマン-ラ ロシュ アーゲー 電気化学発光検出における分枝鎖アミン
WO2018141768A1 (fr) 2017-02-02 2018-08-09 Roche Diagnostics Gmbh Dosage immunologique utilisant au moins deux agents de liaison spécifiques à un analyte pegylés
US11077444B2 (en) 2017-05-23 2021-08-03 Roche Molecular Systems, Inc. Packaging for a molecular diagnostic cartridge
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US11943876B2 (en) 2017-10-24 2024-03-26 Dexcom, Inc. Pre-connected analyte sensors
EP3781600A1 (fr) 2018-04-18 2021-02-24 F. Hoffmann-La Roche AG Nouveaux anticorps anti-thymidine kinase
JP7488812B2 (ja) * 2018-05-21 2024-05-22 ケムクリン ダイアグノスティックス (シャンハイ) カンパニー リミテッド 化学発光免疫分析測定法及び該方法を使用するシステム、試薬キット
CN112639475A (zh) 2018-08-31 2021-04-09 豪夫迈·罗氏有限公司 Dlbcl的预后指数中的胸苷激酶(tk-1)
EP4004551A1 (fr) 2019-07-22 2022-06-01 F. Hoffmann-La Roche AG Substance p en tant que biomarqueur du sang pour le diagnostic non invasif de l'endométriose
CN114144676A (zh) 2019-07-22 2022-03-04 豪夫迈·罗氏有限公司 S100a6作为血液生物标志物用于子宫内膜异位症的非侵入性诊断
CN114144673A (zh) 2019-07-22 2022-03-04 豪夫迈·罗氏有限公司 S100a8作为血液生物标志物用于子宫内膜异位症的非侵入性诊断
CN114144675A (zh) 2019-07-22 2022-03-04 豪夫迈·罗氏有限公司 S100a9作为血液生物标志物用于子宫内膜异位症的非侵入性诊断
EP4004552A1 (fr) 2019-07-22 2022-06-01 F. Hoffmann-La Roche AG S100a12 en tant que biomarqueur sanguin pour le diagnostic non invasif de l'endométriose
JP2023502360A (ja) 2019-11-15 2023-01-24 エフ.ホフマン-ラ ロシュ アーゲー 患者試料における質量分析測定のためのβ-ラクタム抗生物質の誘導体化
US20220057362A1 (en) 2020-08-21 2022-02-24 Meso Scale Technologies, Llc Auxiliary Electrodes and Methods for Using and Manufacturing the Same
WO2022090455A1 (fr) 2020-11-02 2022-05-05 F. Hoffmann-La Roche Ag Anticorps nucléocapsidiques du sars-cov-2
WO2022207628A1 (fr) 2021-03-30 2022-10-06 F. Hoffmann-La Roche Ag Scf comme biomarqueur sanguin pour le diagnostic non invasif de l'endométriose
JP2024511867A (ja) 2021-04-01 2024-03-15 エフ. ホフマン-ラ ロシュ アーゲー 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのpsp94
CN117337394A (zh) 2021-05-17 2024-01-02 豪夫迈·罗氏有限公司 sFRP4作为血液生物标志物用于子宫腺肌病的非侵入性诊断
IL310671A (en) 2021-08-13 2024-04-01 Meso Scale Technologies Llc Electrochemical cell devices and manufacturing methods
WO2023072904A1 (fr) 2021-10-26 2023-05-04 F. Hoffmann-La Roche Ag Anticorps monoclonaux spécifiques du rbd du sars-cov-2
US20230213476A1 (en) 2022-01-04 2023-07-06 Meso Scale Technologies, Llc. Electrochemical cell devices and methods of manufacturing
WO2023131594A1 (fr) 2022-01-05 2023-07-13 F. Hoffmann-La Roche Ag Dérivatisation de composés dans des échantillons de patients pour la pharmacovigilance thérapeutique (tdm)
WO2023247752A1 (fr) 2022-06-23 2023-12-28 F. Hoffmann-La Roche Ag Procédé de diagnostic de l'endométriose et de classification du stade de l'endométriose
WO2024017982A1 (fr) 2022-07-22 2024-01-25 F. Hoffmann-La Roche Ag Leukotriène a4 hydrolase (lta4h) en tant que biomarqueur (sang) pour le diagnostic du syndrome des ovaires polykystiques
WO2024017985A1 (fr) 2022-07-22 2024-01-25 F. Hoffmann-La Roche Ag Protéine 1 de liaison au facteur de croissance des fibroblastes (fgfbp1) utilisée en tant que biomarqueur (sanguin) pour le diagnostic du syndrome des ovaires polykystiques
WO2024017983A1 (fr) 2022-07-22 2024-01-25 F. Hoffmann-La Roche Ag Protéine de type météorine (metrnl) utilisée en tant que biomarqueur (sang) pour le diagnostic du syndrome des ovaires polykystiques

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL49685A (en) * 1976-05-31 1978-10-31 Technion Res & Dev Foundation Specific binding assay method for determining the concentration of materials and reagent means therefor
US4233144A (en) * 1979-04-16 1980-11-11 Technicon Instruments Corporation Electrode for voltammetric immunoassay
US4280815A (en) * 1979-06-18 1981-07-28 Technicon Instruments Corporation Electrochemiluminescent immunoassay and apparatus therefor
WO1981001883A1 (fr) * 1979-12-19 1981-07-09 Electro Nucleonics Systeme de substrat a amplification chimique de la luminescence chimique pour l'immunochimie
US4293310A (en) * 1980-03-14 1981-10-06 University Of Pittsburgh Photoelectrochemical immunoassay
EP0063810B1 (fr) * 1981-04-29 1986-03-05 Ciba-Geigy Ag Dispositif et trousses pour les analyses immunologiques
US4514508A (en) * 1982-07-06 1985-04-30 Biond Inc. Assaying for a multiplicity of antigens or antibodies with a detection compound
GB2135773B (en) * 1983-01-31 1985-12-04 Boots Celltech Diagnostics Enzyme inhibitor labelled immunoassay
EP0139373A1 (fr) * 1983-08-26 1985-05-02 The Regents Of The University Of California Système pour immunoessais multiples
IL75464A (en) * 1984-06-12 1990-08-31 Orgenics Ltd Method and apparatus for multi-analyte assay
CA1340372C (fr) * 1984-07-09 1999-02-02 John D. Clements Production d'une sous-unite d'enterotoxine lt-b d'e. coli
DK365785A (da) * 1984-09-17 1986-03-18 Hoffmann La Roche Metalcomplexer
US4617265A (en) * 1984-09-19 1986-10-14 Board Of Regents, University Of Texas System Colony blot assay for enterotoxigenic bacteria
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US5120662A (en) * 1989-05-09 1992-06-09 Abbott Laboratories Multilayer solid phase immunoassay support and method of use

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DK173025B1 (da) 1999-11-15
JP2003128689A (ja) 2003-05-08
DK16293A (da) 1993-02-12
WO1987006706A1 (fr) 1987-11-05
JP2648474B2 (ja) 1997-08-27
DE3752345T2 (de) 2002-08-22
JPH01500146A (ja) 1989-01-19
AU605158B2 (en) 1991-01-10
JPH11101800A (ja) 1999-04-13
AU644150B2 (en) 1993-12-02
JPH07309836A (ja) 1995-11-28
FI875732A (fi) 1987-12-28
HK1013653A1 (en) 1999-09-03
JP2674957B2 (ja) 1997-11-12
ATE212030T1 (de) 2002-02-15
FI102017B1 (fi) 1998-09-30
EP0265519A1 (fr) 1988-05-04
DK16293D0 (da) 1993-02-12
EP0658564B1 (fr) 2002-01-16
FI875732A0 (fi) 1987-12-28
AU685071B2 (en) 1998-01-15
DE3751516D1 (de) 1995-10-19
EP0265519A4 (fr) 1990-05-14
EP0647849A3 (fr) 1996-05-15
NO176071C (no) 1995-01-25
IL82411A0 (en) 1987-11-30
NO875476D0 (no) 1987-12-29
ATE127923T1 (de) 1995-09-15
AU7433891A (en) 1991-08-08
KR880701379A (ko) 1988-07-26
JPH09118688A (ja) 1997-05-06
EP0265519B1 (fr) 1995-09-13
JP3509812B2 (ja) 2004-03-22
JP3476679B2 (ja) 2003-12-10
CA1339465C (fr) 1997-09-16
KR960016340B1 (ko) 1996-12-09
DE3751516T2 (de) 1996-02-15
AU7581687A (en) 1987-11-24
JPH07267972A (ja) 1995-10-17
EP0658564A1 (fr) 1995-06-21
NO875476L (no) 1988-02-23
NO176071B (no) 1994-10-17
AU5754094A (en) 1994-05-12
DE3752345D1 (de) 2002-02-21
JPH0737464B2 (ja) 1995-04-26
JP3349279B2 (ja) 2002-11-20
FI102017B (fi) 1998-09-30
EP0647849A2 (fr) 1995-04-12

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