JPS5538321A - S6,2'-cyclopyrimidine nucleoside derivative and its preparation - Google Patents

S6,2'-cyclopyrimidine nucleoside derivative and its preparation

Info

Publication number
JPS5538321A
JPS5538321A JP11133778A JP11133778A JPS5538321A JP S5538321 A JPS5538321 A JP S5538321A JP 11133778 A JP11133778 A JP 11133778A JP 11133778 A JP11133778 A JP 11133778A JP S5538321 A JPS5538321 A JP S5538321A
Authority
JP
Japan
Prior art keywords
formula
cyclopyrimidine
nucleoside derivative
preparation
cyclo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11133778A
Other languages
Japanese (ja)
Inventor
Susumu Shibuya
Toru Ueda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Priority to JP11133778A priority Critical patent/JPS5538321A/en
Publication of JPS5538321A publication Critical patent/JPS5538321A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:An S6,2'-cyclopyrimidine nucleoside derivative of formula I (R is alkoxy, OH, mercapto, or amino group).
EXAMPLE: S6,2'-cyclo-β-D-arabinofuranosyl-O2-methyluracil.
USE: Reagents for biochemical studies, e.g. synthetic substrates for studying the substrate specificity of the nucleic acid metabolic enzymes, such as DNA polymerase, and intermediates for the synthesis of triphosphate showing the inhibitory action on the DNA polymerase.
PROCESS: A 5-halogeno-S2-2'-cyclo-2-thiouridine of formula II (X is halogen) is treated with an alkoxide to give a compound of formula I (R is alkoxy group).
COPYRIGHT: (C)1980,JPO&Japio
JP11133778A 1978-09-12 1978-09-12 S6,2'-cyclopyrimidine nucleoside derivative and its preparation Pending JPS5538321A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11133778A JPS5538321A (en) 1978-09-12 1978-09-12 S6,2'-cyclopyrimidine nucleoside derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11133778A JPS5538321A (en) 1978-09-12 1978-09-12 S6,2'-cyclopyrimidine nucleoside derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5538321A true JPS5538321A (en) 1980-03-17

Family

ID=14558632

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11133778A Pending JPS5538321A (en) 1978-09-12 1978-09-12 S6,2'-cyclopyrimidine nucleoside derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5538321A (en)

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