JPS5536419A - 2-substituted adenosine derivative and its preparation - Google Patents

2-substituted adenosine derivative and its preparation

Info

Publication number
JPS5536419A
JPS5536419A JP10965578A JP10965578A JPS5536419A JP S5536419 A JPS5536419 A JP S5536419A JP 10965578 A JP10965578 A JP 10965578A JP 10965578 A JP10965578 A JP 10965578A JP S5536419 A JPS5536419 A JP S5536419A
Authority
JP
Japan
Prior art keywords
compound
alkoxy
preparation
antiviral activity
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10965578A
Other languages
Japanese (ja)
Other versions
JPS633875B2 (en
Inventor
Toru Ueda
Akira Matsuda
Yuji Nomoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Priority to JP10965578A priority Critical patent/JPS5536419A/en
Publication of JPS5536419A publication Critical patent/JPS5536419A/en
Publication of JPS633875B2 publication Critical patent/JPS633875B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I (R1 is O or imino; R2 is alkoxy, OH or NH2).
EXAMPLE: Adenosine-2-carboximic acid methyl ester.
USE: A reagent for biochemistry. A synthetic intermediate of a compound having bioactivity such as antiviral activity. For example, a synthetic substrate for the biochemical or pharmacological investigation of the activity of enzyme which concerns with metabolism of nucleic acid-relating substance in living body. 2-Methyladenosine having antiviral activity can be derived from its 2-carboxylic acid derivative.
PROCESS: Reaction of a compound II (Y, Z are H or protecting groups) with an alkoxide gives an objective compound III (R2a is alkoxy), which can be hydrolyzed to another objective compound IV by acid hydrolysis. The R2a of the compound IV can be converted to OH by alkali hydrolysis of the compound IV.
COPYRIGHT: (C)1980,JPO&Japio
JP10965578A 1978-09-08 1978-09-08 2-substituted adenosine derivative and its preparation Granted JPS5536419A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10965578A JPS5536419A (en) 1978-09-08 1978-09-08 2-substituted adenosine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10965578A JPS5536419A (en) 1978-09-08 1978-09-08 2-substituted adenosine derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS5536419A true JPS5536419A (en) 1980-03-14
JPS633875B2 JPS633875B2 (en) 1988-01-26

Family

ID=14515785

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10965578A Granted JPS5536419A (en) 1978-09-08 1978-09-08 2-substituted adenosine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5536419A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5852223A (en) * 1981-09-21 1983-03-28 Ajinomoto Co Inc Deaminase inhibitor
WO2001027131A1 (en) * 1999-10-14 2001-04-19 Pfizer Limited Purine derivatives
WO2001027130A1 (en) * 1999-10-14 2001-04-19 Pfizer Limited Purine derivatives
WO2000077018A3 (en) * 1999-06-15 2001-12-06 Pfizer Ltd Purine derivatives

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113260984A (en) 2018-12-28 2021-08-13 京瓷办公信息系统株式会社 Monitoring system, monitoring method, and monitoring program

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5852223A (en) * 1981-09-21 1983-03-28 Ajinomoto Co Inc Deaminase inhibitor
JPH0155250B2 (en) * 1981-09-21 1989-11-22 Ajinomoto Kk
WO2000077018A3 (en) * 1999-06-15 2001-12-06 Pfizer Ltd Purine derivatives
US6900309B1 (en) 1999-06-15 2005-05-31 Pfizer Inc Purine derivatives
WO2001027131A1 (en) * 1999-10-14 2001-04-19 Pfizer Limited Purine derivatives
WO2001027130A1 (en) * 1999-10-14 2001-04-19 Pfizer Limited Purine derivatives

Also Published As

Publication number Publication date
JPS633875B2 (en) 1988-01-26

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