JPS5540624A - 1-(2-deoxy-2-alkylthio-beta-d-arabinofuranosyl)pyrimidine derivative and its preparation - Google Patents

1-(2-deoxy-2-alkylthio-beta-d-arabinofuranosyl)pyrimidine derivative and its preparation

Info

Publication number
JPS5540624A
JPS5540624A JP11350178A JP11350178A JPS5540624A JP S5540624 A JPS5540624 A JP S5540624A JP 11350178 A JP11350178 A JP 11350178A JP 11350178 A JP11350178 A JP 11350178A JP S5540624 A JPS5540624 A JP S5540624A
Authority
JP
Japan
Prior art keywords
compound
arabinofuranosyl
deoxy
alkylthio
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11350178A
Other languages
Japanese (ja)
Inventor
Susumu Shibuya
Toru Ueda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Priority to JP11350178A priority Critical patent/JPS5540624A/en
Publication of JPS5540624A publication Critical patent/JPS5540624A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I or II(R1 is alkoxy or OH; R2 is H or protecting group; R3 is alkyl; R4 is OH, SH, alkylthio or NH2).
EXAMPLE: 1-(2-Deoxy-2-methylthio-β-D-arabinofuranosyl)-O2-methyluracil.
USE: Reagent for biochemical research. Possible anti-tumor and anti-viral agent. An intermediate of 5'-triphosphoric acid derivative which is expected as an inhibitor of DNA-synthetase. A reagent for the investigation of the metabolism of a nucleic acid- relating substance such as an anti-viral agent, 1-(2-deoxy-2-methoxy-β-D-arabinofuranosyl)uracil, etc.
PROCESS: An objective compound IV is prepared by reacting a compound III with an alkali and an alkylating agent in a protonic solvent. The compound IV can be converted to another objective compound V by hydrolysis, and further converted to the other objective compound VI by protecting the OH groups and reacting with phosphoric sulfide.
COPYRIGHT: (C)1980,JPO&Japio
JP11350178A 1978-09-14 1978-09-14 1-(2-deoxy-2-alkylthio-beta-d-arabinofuranosyl)pyrimidine derivative and its preparation Pending JPS5540624A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11350178A JPS5540624A (en) 1978-09-14 1978-09-14 1-(2-deoxy-2-alkylthio-beta-d-arabinofuranosyl)pyrimidine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11350178A JPS5540624A (en) 1978-09-14 1978-09-14 1-(2-deoxy-2-alkylthio-beta-d-arabinofuranosyl)pyrimidine derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5540624A true JPS5540624A (en) 1980-03-22

Family

ID=14613916

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11350178A Pending JPS5540624A (en) 1978-09-14 1978-09-14 1-(2-deoxy-2-alkylthio-beta-d-arabinofuranosyl)pyrimidine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5540624A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6248787A (en) * 1985-08-28 1987-03-03 Iida Sangyo Kk Hot-melt type thermosetting body sealer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6248787A (en) * 1985-08-28 1987-03-03 Iida Sangyo Kk Hot-melt type thermosetting body sealer

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