JPS57115184A - Preparation of optical active (s)-beta-aminoglutaric acid monoalkyl ester - Google Patents

Preparation of optical active (s)-beta-aminoglutaric acid monoalkyl ester

Info

Publication number
JPS57115184A
JPS57115184A JP55186819A JP18681980A JPS57115184A JP S57115184 A JPS57115184 A JP S57115184A JP 55186819 A JP55186819 A JP 55186819A JP 18681980 A JP18681980 A JP 18681980A JP S57115184 A JPS57115184 A JP S57115184A
Authority
JP
Japan
Prior art keywords
ester
aminoglutaric acid
optical active
group
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55186819A
Other languages
Japanese (ja)
Other versions
JPS644760B2 (en
Inventor
Hamao Umezawa
Masaji Ono
Junzo Hasegawa
Shigeki Hamaguchi
Masahiro Ogura
Hajime Kawarada
Kiyoshi Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Priority to JP55186819A priority Critical patent/JPS57115184A/en
Priority to US06/328,696 priority patent/US4415657A/en
Priority to GB8137930A priority patent/GB2090592B/en
Priority to DE19813150810 priority patent/DE3150810A1/en
Priority to BE0/206941A priority patent/BE891632A/en
Priority to FR8124534A priority patent/FR2497230A1/en
Publication of JPS57115184A publication Critical patent/JPS57115184A/en
Publication of JPS644760B2 publication Critical patent/JPS644760B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To prepare the titled optical active compound, by hydrolyzing one ester group of β-protected aminoglutaric acid dialkyl ester using a specific fungus, followed by releasing the amino-protecting group.
CONSTITUTION: A fungus (e.g., Candida arborea, IAM4147) belonging to the genus, Candida, Pichia, etc., capable of hydrolyzing selectively only one ester of a β-protected aminoglutaric acid dialkyl ester shown by the formulaI[R is 1W 4C alkyl; A is amino-protecting group (e.g., benzyl group, or benzyloxycarbonyl group) releasable by catalytic reduction or mild hydrolysis], is used. Namely, the culture solution of the fungus, its mold (treated mold) is blended with the compound shown by the formulaIin an aqueous medium, reacted at a pH of about 3W11 at about 15W50°C to form a monoalkyl ester, which is reduced so that the amino-protecting group is released, to give an optical active (S)-β- aminoglutaric acid monoalkyl ester shown by the formula II.
COPYRIGHT: (C)1982,JPO&Japio
JP55186819A 1980-12-30 1980-12-30 Preparation of optical active (s)-beta-aminoglutaric acid monoalkyl ester Granted JPS57115184A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP55186819A JPS57115184A (en) 1980-12-30 1980-12-30 Preparation of optical active (s)-beta-aminoglutaric acid monoalkyl ester
US06/328,696 US4415657A (en) 1980-12-30 1981-12-08 Process for preparation of an optically active monoalkyl ester of β-(S)-aminoglutaric acid
GB8137930A GB2090592B (en) 1980-12-30 1981-12-16 Process for preparation of an optically active monoalkyl ester of b-(s)-aminoglutaric acid
DE19813150810 DE3150810A1 (en) 1980-12-30 1981-12-22 METHOD FOR PRODUCING AN OPTICAL ACTIVE MONOALKYLESTER OF SS (S) AMINOGLUTAR ACID
BE0/206941A BE891632A (en) 1980-12-30 1981-12-28 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE MONOALKYL ESTERS OF ??? - (S) -AMINOGLUTARIC ACID
FR8124534A FR2497230A1 (en) 1980-12-30 1981-12-30 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE MONOALKYL ESTERS OF B- (S) -AMINOGLUTARIC ACID

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55186819A JPS57115184A (en) 1980-12-30 1980-12-30 Preparation of optical active (s)-beta-aminoglutaric acid monoalkyl ester

Publications (2)

Publication Number Publication Date
JPS57115184A true JPS57115184A (en) 1982-07-17
JPS644760B2 JPS644760B2 (en) 1989-01-26

Family

ID=16195147

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55186819A Granted JPS57115184A (en) 1980-12-30 1980-12-30 Preparation of optical active (s)-beta-aminoglutaric acid monoalkyl ester

Country Status (1)

Country Link
JP (1) JPS57115184A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984004543A1 (en) * 1983-05-09 1984-11-22 Sumitomo Chemical Co Process for preparing optically active benzyl alcohol compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984004543A1 (en) * 1983-05-09 1984-11-22 Sumitomo Chemical Co Process for preparing optically active benzyl alcohol compounds

Also Published As

Publication number Publication date
JPS644760B2 (en) 1989-01-26

Similar Documents

Publication Publication Date Title
FI890388A0 (en) Process for Preparation of (S) -ketoprofen
ES8202825A1 (en) Esters of hydroxylalkyl-purines, processes for preparing them and therapeutical composition containing these esters as active ingredients.
IE790175L (en) Cyano esters; optically active acids
IE790111L (en) 2-pyrrolidones and their conversion to amino acids
JPS57146593A (en) Preparation of ribofuranosyltriazole derivative
JPS56128774A (en) New physiologically active substance ebelactone and its preparation
JPS5794295A (en) Preparation of optically active ester and/or acid
JPS57115184A (en) Preparation of optical active (s)-beta-aminoglutaric acid monoalkyl ester
JPS562929A (en) Preparation of optically active cyclopentenolone
JPS57198098A (en) Preparation of optically active monoester monocarboxylic acid
JPS5214745A (en) Preparation of phenylcarbamic acid esters
JPS57145896A (en) Glycolipid and its preparation by fermentation
EP0321849A3 (en) Method for the enzymatic hydrolysis of alpha-aminoadipinyl monoamino compounds
JPS57212105A (en) Plant growth regulating agent
AU9004682A (en) Preparation of aminomethylphosphonic acid
JPS5536419A (en) 2-substituted adenosine derivative and its preparation
GR3001767T3 (en) Stable aqueous solution of vincristine sulfate
ES2170841T3 (en) PROCEDURE FOR THE PREPARATION OF 4,4,4-TRIFLUORO-3 (R) -THYL HYDROXY-BUTANOATE.
JPS6440453A (en) Racemization of optically active serine
JPS57152894A (en) Preparation of optically active carboxylic acid ester and optically active carboxylic acid
JPS5771395A (en) Preparation of optically active monoalkyl beta-(r)-aminoglutarate
JPS57152895A (en) Biochemical process for optical resolution of dl-pantolactone
JPS5424846A (en) Preparation of substituted phenylacetic acid
JPS57132891A (en) Preparation of optically active beta-(s)-aminoglutaric monoalkyl ester
JPS53118588A (en) Preparation of peptidase