JPS5538322A - S6,5'-cyclopyrimidine nucleoside derivative and its preparation - Google Patents

S6,5'-cyclopyrimidine nucleoside derivative and its preparation

Info

Publication number
JPS5538322A
JPS5538322A JP11133878A JP11133878A JPS5538322A JP S5538322 A JPS5538322 A JP S5538322A JP 11133878 A JP11133878 A JP 11133878A JP 11133878 A JP11133878 A JP 11133878A JP S5538322 A JPS5538322 A JP S5538322A
Authority
JP
Japan
Prior art keywords
formula
cyclopyrimidine
nucleoside derivative
cyclo
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11133878A
Other languages
Japanese (ja)
Inventor
Susumu Shibuya
Toru Ueda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Priority to JP11133878A priority Critical patent/JPS5538322A/en
Publication of JPS5538322A publication Critical patent/JPS5538322A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

NEW MATERIAL:An S6,5'-cyclopyrimidine nucleoside derivative of formula I (R is alkoxy, mercapto, or amino group; Z is H or protecting group).
EXAMPLE: S6,5'-cyclo-2',3'-O-isopropylidene-O2-methyluricine.
USE: Reagents for biochemical studies, e.g. synthetic substrates for studying the substrate specificity of the nucleic acid metabolic enzymes, such as DNA polymerase, and intermediates for the synthesis of triphosphate showing the inhibitory action on the DNA polymerase.
PROCESS: A novel 5-halogeno-S2,5'-cyclo-2-thiouridine of formula II (X is halogen; Z' is protecting group) is treated with an alkoxide to give the objective substance of formula I (R is alkoxy group).
COPYRIGHT: (C)1980,JPO&Japio
JP11133878A 1978-09-12 1978-09-12 S6,5'-cyclopyrimidine nucleoside derivative and its preparation Pending JPS5538322A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11133878A JPS5538322A (en) 1978-09-12 1978-09-12 S6,5'-cyclopyrimidine nucleoside derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11133878A JPS5538322A (en) 1978-09-12 1978-09-12 S6,5'-cyclopyrimidine nucleoside derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5538322A true JPS5538322A (en) 1980-03-17

Family

ID=14558656

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11133878A Pending JPS5538322A (en) 1978-09-12 1978-09-12 S6,5'-cyclopyrimidine nucleoside derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5538322A (en)

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